1981 …2024

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2020

High-fat diet induces endoplasmic reticulum stress to promote chondrocyte apoptosis in mouse knee joints

Tan, L., Harper, L., McNulty, M. A., Carlson, C. S. & Yammani, R. R., Jan 1 2020, (Accepted/In press) In : FASEB Journal.

Research output: Contribution to journalArticle

Open Access

Naturally occurring osteoarthritis in male mice with an extended lifespan

Ewart, D., Harper, L., Gravely, A., Miller, R. A., Carlson, C. S. & Loeser, R. F., Jan 2 2020, In : Connective Tissue Research. 61, 1, p. 95-103 9 p.

Research output: Contribution to journalArticle

1 Scopus citations
2019

Evaluation of the Suitability of Miniature Pigs as an Animal Model of Juvenile Osteochondritis Dissecans

Tóth, F., Johnson, C. P., Mills, B., Nissi, M. J., Nykänen, O., Ellermann, J., Ludwig, K. D., Tompkins, M. & Carlson, C. S., Oct 1 2019, In : Journal of Orthopaedic Research. 37, 10, p. 2130-2137 8 p.

Research output: Contribution to journalArticle

1 Scopus citations
2018

Effects of Monoclonal Antibodies against Nerve Growth Factor on Healthy Bone and Joint Tissues in Mice, Rats, and Monkeys: Histopathologic, Biomarker, and Microcomputed Tomographic Assessments

Gropp, K. E., Carlson, C. S., Evans, M. G., Bagi, C. M., Reagan, W. J., Hurst, S. I., Shelton, D. L. & Zorbas, M. A., Jun 1 2018, In : Toxicologic Pathology. 46, 4, p. 408-420 13 p.

Research output: Contribution to journalArticle

2 Scopus citations

Expression of p16INK 4a is a biomarker of chondrocyte aging but does not cause osteoarthritis

Diekman, B. O., Sessions, G. A., Collins, J. A., Knecht, A. K., Strum, S. L., Mitin, N. K., Carlson, C. S., Loeser, R. F. & Sharpless, N. E., Aug 2018, In : Aging cell. 17, 4, e12771.

Research output: Contribution to journalArticle

Open Access
15 Scopus citations
1 Scopus citations

Juvenile osteochondritis dissecans of the knee is a result of failure of the blood supply to growth cartilage and osteochondrosis

Olstad, K., Shea, K. G., Cannamela, P. C., Polousky, J. D., Ekman, S., Ytrehus, B. & Carlson, C. S., Dec 2018, In : Osteoarthritis and Cartilage. 26, 12, p. 1691-1698 8 p.

Research output: Contribution to journalArticle

2 Scopus citations

Quantitative MRI helps to detect hip ischemia: Preclinical model of legg-calvé-perthes disease

Johnson, C. P., Wang, L., Tóth, F., Aruwajoye, O., Carlson, C. S., Kim, H. K. W. & Ellermann, J. M., Nov 2018, In : Radiology. 289, 2, p. 386-395 10 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations
2017

Dystrophic Mineralization of Costal Cartilage in Hartley Guinea Pigs

Schauer, A. M., Schucker, A. & Carlson, C. S., Apr 1 2017, In : Toxicologic Pathology. 45, 3, p. 435-439 5 p.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations

Proliferative Cartilaginous Lesions in the Calcaneal Tendons of huNOG Mice

MacLeod, A. M., Treuting, P. M. & Carlson, C. S., Oct 1 2017, In : Toxicologic Pathology. 45, 7, p. 952-956 5 p.

Research output: Contribution to journalArticle

Quantification and biodistribution of iron oxide nanoparticles in the primary clearance organs of mice using T1 contrast for heating

Zhang, J., Ring, H. L., Hurley, K. R., Shao, Q., Carlson, C. S., Idiyatullin, D., Manuchehrabadi, N., Hoopes, P. J., Haynes, C. L., Bischof, J. C. & Garwood, M., Aug 2017, In : Magnetic resonance in medicine. 78, 2, p. 702-712 11 p.

Research output: Contribution to journalArticle

Open Access
20 Scopus citations
Open Access
16 Scopus citations

Reduced Osteoarthritis Severity in Aged Mice With Deletion of Macrophage Migration Inhibitory Factor

Rowe, M. A., Harper, L. R., McNulty, M. A., Lau, A. G., Carlson, C. S., Leng, L., Bucala, R. J., Miller, R. A. & Loeser, R. F., Feb 1 2017, In : Arthritis and Rheumatology. 69, 2, p. 352-361 10 p.

Research output: Contribution to journalArticle

Open Access
13 Scopus citations

The Effect of Surgical Technique and Spacer Texture on Bone Regeneration: A Caprine Study Using the Masquelet Technique

Luangphakdy, V., Elizabeth Pluhar, G., Piuzzi, N. S., D’Alleyrand, J. C., Carlson, C. S., Bechtold, J. E., Forsberg, J. & Muschler, G. F., Oct 1 2017, In : Clinical orthopaedics and related research. 475, 10, p. 2575-2585 11 p.

Research output: Contribution to journalArticle

Open Access
7 Scopus citations

Wnt10b and Dkk-1 gene therapy differentially influenced trabecular bone architecture, soft tissue integrity, and osteophytosis in a skeletally mature rat model of osteoarthritis

Mason, J. B., Gurda, B. L., Hankenson, K. D., Harper, L. R., Carlson, C. S., Wilson, J. M. & Richardson, D. W., Nov 2 2017, In : Connective Tissue Research. 58, 6, p. 542-552 11 p.

Research output: Contribution to journalArticle

1 Scopus citations
2016

Osteochondrosis prevalence and severity at 12 and 24 weeks of age in commercial pigs with and without organic-complexed trace mineral supplementation

Tóth, F., Torrison, J. L., Harper, L., Bussieres, D., Wilson, M. E., Crenshaw, T. D. & Carlson, C. S., Sep 2016, In : Journal of animal science. 94, 9, p. 3817-3825 9 p.

Research output: Contribution to journalArticle

6 Scopus citations

Oxidative stress promotes peroxiredoxin hyperoxidation and attenuates pro-survival signaling in aging chondrocytes

Collins, J. A., Wood, S. T., Nelson, K. J., Rowe, M. A., Carlson, C. S., Chubinskaya, S., Poole, L. B., Furdui, C. M. & Loeser, R. F., Mar 25 2016, In : Journal of Biological Chemistry. 291, 13, p. 6641-6654 14 p.

Research output: Contribution to journalArticle

29 Scopus citations
2015

An Update on the Pathogenesis of Osteochondrosis

Olstad, K., Ekman, S. & Carlson, C. S., Sep 24 2015, In : Veterinary pathology. 52, 5, p. 785-802 18 p.

Research output: Contribution to journalArticle

31 Scopus citations

Bone Disease in the Common Marmoset: Radiographic and Histological Findings

Olson, E. J., Shaw, G. C., Hutchinson, E. K., Schultz-Darken, N., Bolton, I. D., Parker, J. B., Morrison, J. M., Baxter, V. K., Pate, K. A. M., Mankowski, J. L. & Carlson, C. S., Sep 24 2015, In : Veterinary pathology. 52, 5, p. 883-893 11 p.

Research output: Contribution to journalArticle

3 Scopus citations

Improved visualization of cartilage canals using quantitative susceptibility mapping

Nissi, M. J., Tóth, F., Wang, L., Carlson, C. S., Ellermann, J. M. & Kim, J. E., Jul 13 2015, In : PloS one. 10, 7, e0132167.

Research output: Contribution to journalArticle

20 Scopus citations

Multiparametric MRI of epiphyseal cartilage necrosis (osteochondrosis) with histological validation in a goat model

Wang, L., Nissi, M. J., Tóth, F., Shaver, J., Johnson, C. P., Zhang, J., Garwood, M., Carlson, C. S. & Ellermann, J. M., Oct 16 2015, In : PloS one. 10, 10, e0140400.

Research output: Contribution to journalArticle

10 Scopus citations

Novel Application of Magnetic Resonance Imaging Demonstrates Characteristic Differences in Vasculature at Predilection Sites of Osteochondritis Dissecans

Tóth, F., Nissi, M. J., Ellermann, J. M., Wang, L., Shea, K. G., Polousky, J. & Carlson, C. S., Oct 1 2015, In : American Journal of Sports Medicine. 43, 10, p. 2522-2527 6 p.

Research output: Contribution to journalArticle

21 Scopus citations

Osteochondrosis Can Lead to Formation of Pseudocysts and True Cysts in the Subchondral Bone of Horses

Olstad, K., Østevik, L., Carlson, C. S. & Ekman, S., Sep 24 2015, In : Veterinary pathology. 52, 5, p. 862-872 11 p.

Research output: Contribution to journalArticle

6 Scopus citations
23 Scopus citations
2014

Susceptibility weighted imaging of cartilage canals in porcine epiphyseal growth cartilage ex vivo and in vivo

Nissi, M. J., Toth, F., Zhang, J., Schmitter, S., Benson, M., Carlson, C. S. & Ellermann, J. M., Jun 2014, In : Magnetic resonance in medicine. 71, 6, p. 2197-2205 9 p.

Research output: Contribution to journalArticle

19 Scopus citations
2013

Disease Progression and Phasic Changes in Gene Expression in a Mouse Model of Osteoarthritis

Loeser, R. F., Olex, A. L., McNulty, M. A., Carlson, C. S., Callahan, M., Ferguson, C. & Fetrow, J. S., Jan 28 2013, In : PloS one. 8, 1, e54633.

Research output: Contribution to journalArticle

61 Scopus citations
17 Scopus citations

Local Morphological Response of the Distal Femoral Articular-Epiphyseal Cartilage Complex of Young Foals to Surgical Stab Incision and Potential Relevance to Cartilage Injury and Repair in Children

Olstad, K., Hendrickson, E. H. S., Ekman, S., Carlson, C. S. & Dolvik, N. I., Jul 1 2013, In : Cartilage. 4, 3, p. 239-248 10 p.

Research output: Contribution to journalArticle

5 Scopus citations

MRI rotating frame relaxation measurements for articular cartilage assessment

Ellermann, J., Ling, W., Nissi, M. J., Arendt, E., Carlson, C. S., Garwood, M., Michaeli, S. & Mangia, S., Nov 1 2013, In : Magnetic Resonance Imaging. 31, 9, p. 1537-1543 7 p.

Research output: Contribution to journalArticle

25 Scopus citations

Non-terminal animal model of post-traumatic osteoarthritis induced by acute joint injury

Boyce, M. K., Trumble, T. N., Carlson, C. S., Groschen, D. M., Merritt, K. A. & Brown, M. P., May 1 2013, In : Osteoarthritis and Cartilage. 21, 5, p. 746-755 10 p.

Research output: Contribution to journalArticle

17 Scopus citations

Serum albumin and body weight as biomarkers for the antemortem identification of bone and gastrointestinal disease in the common marmoset

Baxter, V. K., Shaw, G. C., Sotuyo, N. P., Carlson, C. S., Olson, E. J., Christine Zink, M., Mankowski, J. L., Adams, R. J., Hutchinson, E. K. & Metcalf Pate, K. A., Dec 6 2013, In : PloS one. 8, 12, e82747.

Research output: Contribution to journalArticle

12 Scopus citations

Tissue mineral concentrations and osteochondrosis lesions in prolific sows across parities 0 through

Crenshaw, T. D., Schneider, D. K., Carlson, C. S., Parker, J. B., Sonderman, J. P., Ward, T. L. & Wilson, M. E., Mar 1 2013, In : Journal of animal science. 91, 3, p. 1255-1269 15 p.

Research output: Contribution to journalArticle

3 Scopus citations
38 Scopus citations
2012

GEP constitutes a negative feedback loop with MyoD and acts as a novel mediator in controlling skeletal muscle differentiation

Wang, D., Bai, X., Tian, Q., Lai, Y., Lin, E. A., Shi, Y., Mu, X., Feng, J. Q., Carlson, C. S. & Liu, C. J., Jun 1 2012, In : Cellular and Molecular Life Sciences. 69, 11, p. 1855-1873 19 p.

Research output: Contribution to journalArticle

10 Scopus citations

Histopathology of naturally occurring and surgically induced osteoarthritis in mice

McNulty, M. A., Loeser, R. F., Davey, C., Callahan, M. F., Ferguson, C. M. & Carlson, C. S., Aug 1 2012, In : Osteoarthritis and Cartilage. 20, 8, p. 949-956 8 p.

Research output: Contribution to journalArticle

40 Scopus citations

Inflammation, apoptosis, and necrosis induced by neoadjuvant fas ligand gene therapy improves survival of dogs with spontaneous bone cancer

Modiano, J. F., Bellgrau, D., Cutter, G. R., Lana, S. E., Ehrhart, N. P., Ehrhart, E., Wilke, V. L., Charles, J. B., Munson, S., Scott, M. C., Pozniak, J., Carlson, C. S., Schaack, J. & Duke, R. C., Dec 2012, In : Molecular Therapy. 20, 12, p. 2234-2243 10 p.

Research output: Contribution to journalArticle

25 Scopus citations

Microarray analysis reveals age-related differences in gene expression during the development of osteoarthritis in mice

Loeser, R. F., Olex, A. L., McNulty, M. A., Carlson, C. S., Callahan, M. F., Ferguson, C. M., Chou, J., Leng, X. & Fetrow, J. S., Mar 1 2012, In : Arthritis and rheumatism. 64, 3, p. 705-717 13 p.

Research output: Contribution to journalArticle

123 Scopus citations
3 Scopus citations

The oncogene LRF is a survival factor in chondrosarcoma and contributes to tumor malignancy and drug resistance

Kumari, R., Li, H., Haudenschild, D. R., Fierro, F., Carlson, C. S., Overn, P., Gupta, L., Gupta, K., Nolta, J., Yik, J. H. N. & Di Cesare, P. E., Nov 1 2012, In : Carcinogenesis. 33, 11, p. 2076-2083 8 p.

Research output: Contribution to journalArticle

12 Scopus citations
2011

A comprehensive histological assessment of osteoarthritis lesions in mice

McNulty, M. A., Loeser, R. F., Davey, C. S., Callahan, M. F., Ferguson, C. M. & Carlson, C. S., Oct 1 2011, In : Cartilage. 2, 4, p. 354-363 10 p.

Research output: Contribution to journalArticle

23 Scopus citations

Development of a fracture osteomyelitis model in the rat femur

Robinson, D. A., Bechtold, J. E., Carlson, C. S., Evans, R. B. & Conzemius, M. G., Jan 1 2011, In : Journal of Orthopaedic Research. 29, 1, p. 131-137 7 p.

Research output: Contribution to journalArticle

10 Scopus citations

Early lesions of articular osteochondrosis in the distal femur of foals

Olstad, K., Ytrehus, B., Ekman, S., Carlson, C. S. & Dolvik, N. I., Nov 29 2011, In : Veterinary pathology. 48, 6, p. 1165-1175 11 p.

Research output: Contribution to journalArticle

41 Scopus citations

Inhibition of angiogenesis and suppression of colorectal cancer metastatic to the liver using the Sleeping Beauty Transposon System

Belur, L. R., Podetz-Pedersen, K. M., Sorenson, B. S., Hsu, A. H., Parker, J. B., Carlson, C. S., Saltzman, D. A., Ramakrishnan, S. & McIvor, R. S., Feb 10 2011, In : Molecular Cancer. 10, 14.

Research output: Contribution to journalArticle

28 Scopus citations
2010

Anti-tumor immune response correlates with neurological symptoms in a dog with spontaneous astrocytoma treated by gene and vaccine therapy

Pluhar, L., Grogan, P. T., Seiler, C., Goulart, M., SantaCruz, K. S., Carlson, C. S., Chen, W., Olin, M. R., Lowenstein, P. R., Castro, M. G., Haines, S. J. & Ohlfest, J. R., Apr 26 2010, In : Vaccine. 28, 19, p. 3371-3378 8 p.

Research output: Contribution to journalArticle

34 Scopus citations

Effect of intra-articular pressurization associated with arthroscopy on the immature physis: Investigation in an animal model

Deal, D. N., Ma, J., Apel, P., Novak, V., Carlson, C. S., Parker, J. B., Olson, E. J., Rieser, G. R., Smith, T. L. & Shilt, J. S., Jan 1 2010, In : Journal of Pediatric Orthopaedics. 30, 1, p. 21-25 5 p.

Research output: Contribution to journalArticle

The novel carbohydrate tumor antigen C2-O-sLex is upregulated in canine gastric carcinomas

Janke, L., Carlson, C. S. & St. Hill, C. A., Jul 16 2010, In : Veterinary pathology. 47, 3, p. 455-461 7 p.

Research output: Contribution to journalArticle

5 Scopus citations

The OARSI histopathology initiative - recommendations for histological assessments of osteoarthritis in the rat

Gerwin, N., Bendele, A. M., Glasson, S. & Carlson, C. S., Oct 1 2010, In : Osteoarthritis and Cartilage. 18, SUPPL. 3, p. S24-S34

Research output: Contribution to journalArticle

209 Scopus citations
2009

A Comparative Analysis of 7.0-Tesla Magnetic Resonance Imaging and Histology Measurements of Knee Articular Cartilage in a Canine Posterolateral Knee Injury Model: A Preliminary Analysis

Pepin, S. R., Griffith, C. J., Wijdicks, C. A., Goerke, U., McNulty, M. A., Parker, J. B., Carlson, C. S., Ellermann, J. & Laprade, R. F., Nov 1 2009, In : American Journal of Sports Medicine. 37, 1_suppl, p. 119S-124S

Research output: Contribution to journalArticle

14 Scopus citations