If you made any changes in Pure, your changes will be visible here soon.

Research Output 1981 2020

2020
1 Citation (Scopus)

Naturally occurring osteoarthritis in male mice with an extended lifespan

Ewart, D., Harper, L., Gravely, A., Miller, R. A., Carlson, C. S. & Loeser, R. F., Jan 2 2020, In : Connective Tissue Research. 61, 1, p. 95-103 9 p.

Research output: Contribution to journalArticle

Osteoarthritis
Cartilage
Articular Cartilage
Testing
Nutrition
2019
1 Citation (Scopus)

Evaluation of the Suitability of Miniature Pigs as an Animal Model of Juvenile Osteochondritis Dissecans

Tóth, F., Johnson, C. P., Mills, B., Nissi, M. J., Nykänen, O., Ellermann, J., Ludwig, K. D., Tompkins, M. & Carlson, C. S., Oct 1 2019, In : Journal of Orthopaedic Research. 37, 10, p. 2130-2137 8 p.

Research output: Contribution to journalArticle

Osteochondritis Dissecans
Swine
Animal Models
Thigh
Growth Plate
Legg-Calve-Perthes Disease
Growth Plate
Thigh
Wounds and Injuries
Cartilage
2018
1 Citation (Scopus)

Effects of Monoclonal Antibodies against Nerve Growth Factor on Healthy Bone and Joint Tissues in Mice, Rats, and Monkeys: Histopathologic, Biomarker, and Microcomputed Tomographic Assessments

Gropp, K. E., Carlson, C. S., Evans, M. G., Bagi, C. M., Reagan, W. J., Hurst, S. I., Shelton, D. L. & Zorbas, M. A., Jun 1 2018, In : Toxicologic Pathology. 46, 4, p. 408-420 13 p.

Research output: Contribution to journalArticle

Biomarkers
Nerve Growth Factor
Haplorhini
Rats
Bone
13 Citations (Scopus)

Expression of p16INK 4a is a biomarker of chondrocyte aging but does not cause osteoarthritis

Diekman, B. O., Sessions, G. A., Collins, J. A., Knecht, A. K., Strum, S. L., Mitin, N. K., Carlson, C. S., Loeser, R. F. & Sharpless, N. E., Aug 2018, In : Aging cell. 17, 4, e12771.

Research output: Contribution to journalArticle

Open Access
Chondrocytes
Osteoarthritis
Biomarkers
Phenotype
Cartilage
1 Citation (Scopus)
Osteochondritis Dissecans
Growth Plate
Cadaver
Necrosis
Osteochondrosis
1 Citation (Scopus)

Juvenile osteochondritis dissecans of the knee is a result of failure of the blood supply to growth cartilage and osteochondrosis

Olstad, K., Shea, K. G., Cannamela, P. C., Polousky, J. D., Ekman, S., Ytrehus, B. & Carlson, C. S., Dec 2018, In : Osteoarthritis and Cartilage. 26, 12, p. 1691-1698 8 p.

Research output: Contribution to journalArticle

Osteochondritis Dissecans
Osteochondrosis
Cartilage
Knee
Blood

Quantitative MRI helps to detect hip ischemia: Preclinical model of legg-calvé-perthes disease

Johnson, C. P., Wang, L., Tóth, F., Aruwajoye, O., Carlson, C. S., Kim, H. K. W. & Ellermann, J. M., Nov 2018, In : Radiology. 289, 2, p. 386-395 10 p.

Research output: Contribution to journalArticle

Open Access
Legg-Calve-Perthes Disease
Thigh
Hip
Growth Plate
Ischemia
2017

Bones, Joints, Tendons, and Ligaments

Olson, E. J. & Carlson, C. S., Jan 1 2017, Pathologic Basis of Veterinary Disease Expert Consult. Elsevier Inc., p. 954-1008.e2

Research output: Chapter in Book/Report/Conference proceedingChapter

ligaments
tendons
Ligaments
joints (animal)
Tendons

Dystrophic Mineralization of Costal Cartilage in Hartley Guinea Pigs

Schauer, A. M., Schucker, A. & Carlson, C. S., Apr 1 2017, In : Toxicologic Pathology. 45, 3, p. 435-439 5 p.

Research output: Contribution to journalArticle

Cartilage
Guinea Pigs
Animals
Skeletal Muscle
Animal Disease Models
4 Citations (Scopus)
Osteochondritis Dissecans
Osteochondrosis
Goats
Necrosis
Cartilage

Proliferative Cartilaginous Lesions in the Calcaneal Tendons of huNOG Mice

MacLeod, A. M., Treuting, P. M. & Carlson, C. S., Oct 1 2017, In : Toxicologic Pathology. 45, 7, p. 952-956 5 p.

Research output: Contribution to journalArticle

Achilles Tendon
Tendons
Swelling
Bone
Tissue
20 Citations (Scopus)

Quantification and biodistribution of iron oxide nanoparticles in the primary clearance organs of mice using T1 contrast for heating

Zhang, J., Ring, H. L., Hurley, K. R., Shao, Q., Carlson, C. S., Idiyatullin, D., Manuchehrabadi, N., Hoopes, P. J., Haynes, C. L., Bischof, J. C. & Garwood, M., Aug 2017, In : Magnetic resonance in medicine. 78, 2, p. 702-712 11 p.

Research output: Contribution to journalArticle

Open Access
Nanoparticles
Heating
Fever
Iron
Magnetic Fields
16 Citations (Scopus)
Open Access
Osteochondritis Dissecans
Goats
Cartilage
Thigh
Magnetic Resonance Imaging
12 Citations (Scopus)

Reduced Osteoarthritis Severity in Aged Mice With Deletion of Macrophage Migration Inhibitory Factor

Rowe, M. A., Harper, L. R., McNulty, M. A., Lau, A. G., Carlson, C. S., Leng, L., Bucala, R. J., Miller, R. A. & Loeser, R. F., Feb 1 2017, In : Arthritis and Rheumatology. 69, 2, p. 352-361 10 p.

Research output: Contribution to journalArticle

Open Access
Macrophage Migration-Inhibitory Factors
Osteoarthritis
Chondrocytes
Tibial Meniscus
Cartilage
6 Citations (Scopus)

The Effect of Surgical Technique and Spacer Texture on Bone Regeneration: A Caprine Study Using the Masquelet Technique

Luangphakdy, V., Elizabeth Pluhar, G., Piuzzi, N. S., D’Alleyrand, J. C., Carlson, C. S., Bechtold, J. E., Forsberg, J. & Muschler, G. F., Oct 1 2017, In : Clinical orthopaedics and related research. 475, 10, p. 2575-2585 11 p.

Research output: Contribution to journalArticle

Open Access
Bone Regeneration
Membranes
Osteogenesis
Bone and Bones
Periosteum
1 Citation (Scopus)

Wnt10b and Dkk-1 gene therapy differentially influenced trabecular bone architecture, soft tissue integrity, and osteophytosis in a skeletally mature rat model of osteoarthritis

Mason, J. B., Gurda, B. L., Hankenson, K. D., Harper, L. R., Carlson, C. S., Wilson, J. M. & Richardson, D. W., Nov 2 2017, In : Connective Tissue Research. 58, 6, p. 542-552 11 p.

Research output: Contribution to journalArticle

Gene therapy
Osteoarthritis
Genetic Therapy
Rats
Bone
2016
6 Citations (Scopus)

Osteochondrosis prevalence and severity at 12 and 24 weeks of age in commercial pigs with and without organic-complexed trace mineral supplementation

Tóth, F., Torrison, J. L., Harper, L., Bussieres, D., Wilson, M. E., Crenshaw, T. D. & Carlson, C. S., Sep 2016, In : Journal of animal science. 94, 9, p. 3817-3825 9 p.

Research output: Contribution to journalArticle

Osteochondrosis
osteochondrosis
Trace Elements
trace elements
Swine
29 Citations (Scopus)

Oxidative stress promotes peroxiredoxin hyperoxidation and attenuates pro-survival signaling in aging chondrocytes

Collins, J. A., Wood, S. T., Nelson, K. J., Rowe, M. A., Carlson, C. S., Chubinskaya, S., Poole, L. B., Furdui, C. M. & Loeser, R. F., Mar 25 2016, In : Journal of Biological Chemistry. 291, 13, p. 6641-6654 14 p.

Research output: Contribution to journalArticle

Peroxiredoxins
Oxidative stress
Chondrocytes
Oxidative Stress
Aging of materials
2015
31 Citations (Scopus)

An Update on the Pathogenesis of Osteochondrosis

Olstad, K., Ekman, S. & Carlson, C. S., Sep 24 2015, In : Veterinary pathology. 52, 5, p. 785-802 18 p.

Research output: Contribution to journalArticle

Osteochondrosis
osteochondrosis
lesions (animal)
bone formation
Osteogenesis
3 Citations (Scopus)

Bone Disease in the Common Marmoset: Radiographic and Histological Findings

Olson, E. J., Shaw, G. C., Hutchinson, E. K., Schultz-Darken, N., Bolton, I. D., Parker, J. B., Morrison, J. M., Baxter, V. K., Pate, K. A. M., Mankowski, J. L. & Carlson, C. S., Sep 24 2015, In : Veterinary pathology. 52, 5, p. 883-893 11 p.

Research output: Contribution to journalArticle

bone diseases
Callithrix
Callithrix jacchus
Bone Diseases
lesions (animal)
20 Citations (Scopus)

Improved visualization of cartilage canals using quantitative susceptibility mapping

Nissi, M. J., Tóth, F., Wang, L., Carlson, C. S., Ellermann, J. M. & Kim, J. E., Jul 13 2015, In : PloS one. 10, 7, e0132167.

Research output: Contribution to journalArticle

Cartilage
Canals
cartilage
Visualization
image analysis
10 Citations (Scopus)

Multiparametric MRI of epiphyseal cartilage necrosis (osteochondrosis) with histological validation in a goat model

Wang, L., Nissi, M. J., Tóth, F., Shaver, J., Johnson, C. P., Zhang, J., Garwood, M., Carlson, C. S. & Ellermann, J. M., Oct 16 2015, In : PloS one. 10, 10, e0140400.

Research output: Contribution to journalArticle

Osteochondrosis
osteochondrosis
growth plate
Growth Plate
Cartilage
1 Citation (Scopus)

No Bones About It: The Challenges and Rewards of Osteopathology

Gunson, D. E., Carlson, C. S. & Gropp, K. E., Sep 24 2015, In : Veterinary pathology. 52, 5, p. 766-769 4 p.

Research output: Contribution to journalEditorial

Veterinary Pathology
bone diseases
Bone Diseases
Reward
bones
21 Citations (Scopus)

Novel Application of Magnetic Resonance Imaging Demonstrates Characteristic Differences in Vasculature at Predilection Sites of Osteochondritis Dissecans

Tóth, F., Nissi, M. J., Ellermann, J. M., Wang, L., Shea, K. G., Polousky, J. & Carlson, C. S., Oct 1 2015, In : American Journal of Sports Medicine. 43, 10, p. 2522-2527 6 p.

Research output: Contribution to journalArticle

Osteochondritis Dissecans
Osteochondrosis
Magnetic Resonance Imaging
Swine
Blood Vessels
6 Citations (Scopus)

Osteochondrosis Can Lead to Formation of Pseudocysts and True Cysts in the Subchondral Bone of Horses

Olstad, K., Østevik, L., Carlson, C. S. & Ekman, S., Sep 24 2015, In : Veterinary pathology. 52, 5, p. 862-872 11 p.

Research output: Contribution to journalArticle

Osteochondrosis
Bone Cysts
osteochondrosis
lesions (animal)
Horses
23 Citations (Scopus)
Osteochondrosis
Cartilage
Magnetic resonance
Goats
Femur
2014
1 Citation (Scopus)

Pathology in practice

Taulescu, M. A., Carlson, C. S., Amorim, I. F., De Fatima Gärtner, M., Fãrcaş, L., Gal, A. F. & Cãtoi, C., Nov 15 2014, In : Journal of the American Veterinary Medical Association. 245, 10, p. 1103-1105 3 p.

Research output: Contribution to journalComment/debate

19 Citations (Scopus)

Susceptibility weighted imaging of cartilage canals in porcine epiphyseal growth cartilage ex vivo and in vivo

Nissi, M. J., Toth, F., Zhang, J., Schmitter, S., Benson, M., Carlson, C. S. & Ellermann, J. M., Jun 2014, In : Magnetic resonance in medicine. 71, 6, p. 2197-2205 9 p.

Research output: Contribution to journalArticle

Growth Plate
Cartilage
Swine
Growth
Stifle
2013
49 Citations (Scopus)

Articular osteochondrosis: A comparison of naturally-occurring human and animal disease

McCoy, A. M., Toth, F., Dolvik, N. I., Ekman, S., Ellermann, J. M., Olstad, K., Ytrehus, B. & Carlson, C. S., Nov 1 2013, In : Osteoarthritis and Cartilage. 21, 11, p. 1638-1647 10 p.

Research output: Contribution to journalReview article

Osteochondrosis
Animal Diseases
Animals
Joints
Orthopedics

Cause of spinal cord compression in a dog

Wuenschmann, A., Carlson, C., Chalkley, M. & Kovi, R., Jun 1 2013, In : Journal of the American Veterinary Medical Association. 242, 11, p. 1474-1475 2 p.

Research output: Contribution to journalLetter

Extramedullary Hematopoiesis
Dog Diseases
Choristoma
Spinal Cord Compression
dog diseases
60 Citations (Scopus)

Disease Progression and Phasic Changes in Gene Expression in a Mouse Model of Osteoarthritis

Loeser, R. F., Olex, A. L., McNulty, M. A., Carlson, C. S., Callahan, M., Ferguson, C. & Fetrow, J. S., Jan 28 2013, In : PloS one. 8, 1, e54633.

Research output: Contribution to journalArticle

osteoarthritis
disease course
Gene expression
Osteoarthritis
Disease Progression
17 Citations (Scopus)
Osteochondrosis
Cartilage
Swine
Magnetic Resonance Imaging
Barium
5 Citations (Scopus)

Local Morphological Response of the Distal Femoral Articular-Epiphyseal Cartilage Complex of Young Foals to Surgical Stab Incision and Potential Relevance to Cartilage Injury and Repair in Children

Olstad, K., Hendrickson, E. H. S., Ekman, S., Carlson, C. S. & Dolvik, N. I., Jul 1 2013, In : Cartilage. 4, 3, p. 239-248 10 p.

Research output: Contribution to journalArticle

Growth Plate
Cartilage
Articular Cartilage
Thigh
Osteogenesis
25 Citations (Scopus)

MRI rotating frame relaxation measurements for articular cartilage assessment

Ellermann, J., Ling, W., Nissi, M. J., Arendt, E., Carlson, C. S., Garwood, M., Michaeli, S. & Mangia, S., Nov 1 2013, In : Magnetic Resonance Imaging. 31, 9, p. 1537-1543 7 p.

Research output: Contribution to journalArticle

Cartilage
Articular Cartilage
Magnetic resonance imaging
Trypsin
Magnetization
17 Citations (Scopus)

Non-terminal animal model of post-traumatic osteoarthritis induced by acute joint injury

Boyce, M. K., Trumble, T., Carlson, C. S., Groschen, D. M., Merritt, K. A. & Brown, M. P., May 1 2013, In : Osteoarthritis and Cartilage. 21, 5, p. 746-755 10 p.

Research output: Contribution to journalArticle

Cartilage
Osteoarthritis
Animals
Animal Models
Joints
12 Citations (Scopus)

Serum albumin and body weight as biomarkers for the antemortem identification of bone and gastrointestinal disease in the common marmoset

Baxter, V. K., Shaw, G. C., Sotuyo, N. P., Carlson, C. S., Olson, E. J., Christine Zink, M., Mankowski, J. L., Adams, R. J., Hutchinson, E. K. & Metcalf Pate, K. A., Dec 6 2013, In : PloS one. 8, 12, e82747.

Research output: Contribution to journalArticle

bone diseases
Callithrix
Callithrix jacchus
Gastrointestinal Diseases
Callitrichidae
3 Citations (Scopus)

Tissue mineral concentrations and osteochondrosis lesions in prolific sows across parities 0 through

Crenshaw, T. D., Schneider, D. K., Carlson, C. S., Parker, J. B., Sonderman, J. P., Ward, T. L. & Wilson, M. E., Mar 1 2013, In : Journal of animal science. 91, 3, p. 1255-1269 15 p.

Research output: Contribution to journalArticle

Osteochondrosis
osteochondrosis
Parity
lesions (animal)
mineral content
38 Citations (Scopus)
Osteochondritis Dissecans
Osteochondrosis
Growth Plate
Cartilage
Canals
2012
9 Citations (Scopus)

GEP constitutes a negative feedback loop with MyoD and acts as a novel mediator in controlling skeletal muscle differentiation

Wang, D., Bai, X., Tian, Q., Lai, Y., Lin, E. A., Shi, Y., Mu, X., Feng, J. Q., Carlson, C. S. & Liu, C. J., Jun 1 2012, In : Cellular and Molecular Life Sciences. 69, 11, p. 1855-1873 19 p.

Research output: Contribution to journalArticle

Skeletal Muscle
Myoblasts
Skeletal Muscle Fibers
MyoD Protein
Transcription Factors
40 Citations (Scopus)

Histopathology of naturally occurring and surgically induced osteoarthritis in mice

McNulty, M. A., Loeser, R. F., Davey, C., Callahan, M. F., Ferguson, C. M. & Carlson, C. S., Aug 1 2012, In : Osteoarthritis and Cartilage. 20, 8, p. 949-956 8 p.

Research output: Contribution to journalArticle

Cartilage
Osteoarthritis
Articular Cartilage
Joints
Tissue
23 Citations (Scopus)

Inflammation, apoptosis, and necrosis induced by neoadjuvant fas ligand gene therapy improves survival of dogs with spontaneous bone cancer

Modiano, J. F., Bellgrau, D., Cutter, G. R., Lana, S. E., Ehrhart, N. P., Ehrhart, E., Wilke, V. L., Charles, J. B., Munson, S., Scott, M. C., Pozniak, J., Carlson, C. S., Schaack, J. & Duke, R. C., Dec 2012, In : Molecular Therapy. 20, 12, p. 2234-2243 10 p.

Research output: Contribution to journalArticle

Bone Neoplasms
Fas Ligand Protein
Genetic Therapy
Necrosis
Dogs
123 Citations (Scopus)

Microarray analysis reveals age-related differences in gene expression during the development of osteoarthritis in mice

Loeser, R. F., Olex, A. L., McNulty, M. A., Carlson, C. S., Callahan, M. F., Ferguson, C. M., Chou, J., Leng, X. & Fetrow, J. S., Mar 1 2012, In : Arthritis and rheumatism. 64, 3, p. 705-717 13 p.

Research output: Contribution to journalArticle

Microarray Analysis
Osteoarthritis
Joints
Gene Expression
Genes
3 Citations (Scopus)
ras Genes
Plasma Cells
B-Lymphocytes
Multiple Myeloma
Neoplasms
12 Citations (Scopus)

The oncogene LRF is a survival factor in chondrosarcoma and contributes to tumor malignancy and drug resistance

Kumari, R., Li, H., Haudenschild, D. R., Fierro, F., Carlson, C. S., Overn, P., Gupta, L., Gupta, K., Nolta, J., Yik, J. H. N. & Di Cesare, P. E., Nov 1 2012, In : Carcinogenesis. 33, 11, p. 2076-2083 8 p.

Research output: Contribution to journalArticle

Chondrosarcoma
Oncogenes
Drug Resistance
Lymphoma
Survival
2011
23 Citations (Scopus)

A comprehensive histological assessment of osteoarthritis lesions in mice

McNulty, M. A., Loeser, R. F., Davey, C. S., Callahan, M. F., Ferguson, C. M. & Carlson, C. S., Oct 1 2011, In : Cartilage. 2, 4, p. 354-363 10 p.

Research output: Contribution to journalArticle

Stifle
Osteoarthritis
Joints
Cartilage
Principal component analysis
10 Citations (Scopus)

Development of a fracture osteomyelitis model in the rat femur

Robinson, D. A., Bechtold, J. E., Carlson, C. S., Evans, R. B. & Conzemius, M. G., Jan 1 2011, In : Journal of Orthopaedic Research. 29, 1, p. 131-137 7 p.

Research output: Contribution to journalArticle

Osteomyelitis
Femur
Staphylococcus aureus
Stem Cells
Closed Fractures
41 Citations (Scopus)

Early lesions of articular osteochondrosis in the distal femur of foals

Olstad, K., Ytrehus, B., Ekman, S., Carlson, C. S. & Dolvik, N. I., Nov 29 2011, In : Veterinary pathology. 48, 6, p. 1165-1175 11 p.

Research output: Contribution to journalArticle

Osteochondrosis
osteochondrosis
femur
foals
cartilage
28 Citations (Scopus)

Inhibition of angiogenesis and suppression of colorectal cancer metastatic to the liver using the Sleeping Beauty Transposon System

Belur, L. R., Podetz-Pedersen, K. M., Sorenson, B. S., Hsu, A. H., Parker, J. B., Carlson, C. S., Saltzman, D. A., Ramakrishnan, S. & McIvor, R. S., Feb 10 2011, In : Molecular Cancer. 10, 14.

Research output: Contribution to journalArticle

Beauty
Colorectal Neoplasms
Plasmids
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Liver
2010
34 Citations (Scopus)

Anti-tumor immune response correlates with neurological symptoms in a dog with spontaneous astrocytoma treated by gene and vaccine therapy

Pluhar, L., Grogan, P. T., Seiler, C., Goulart, M., SantaCruz, K. S., Carlson, C. S., Chen, W., Olin, M. R., Lowenstein, P. R., Castro, M. G., Haines, S. J. & Ohlfest, J. R., Apr 26 2010, In : Vaccine. 28, 19, p. 3371-3378 8 p.

Research output: Contribution to journalArticle

Active Immunotherapy
Astrocytoma
Genetic Therapy
signs and symptoms (animals and humans)
vaccination