Research Output per year
Research Output 1986 2019
- 50 - 100 out of 123 results
- Type (ascending)
Expression, purification and characterization of recombinant mouse translation initiation factor eIF4E as a dihydrofolate reductase (DHFR) fusion protein
Ghosh, P., Cheng, J., Chou, T. F., Jia, Y., Avdulov, S. V., Bitterman, P. B., Polunovsky, V. A. & Wagner, C. R., Aug 1 2008, In : Protein Expression and Purification. 60, 2, p. 132-139 8 p.Research output: Contribution to journal › Article
Fluorescent tumour imaging of type I IGF receptor in vivo: comparison of antibody-conjugated quantum dots and small-molecule fluorophore
Zhang, H., Zeng, X., Li, Q., Gaillard-Kelly, M., Wagner, C. R. & Yee, D., Jul 7 2009, In : British Journal of Cancer. 101, 1, p. 71-79 9 p.Research output: Contribution to journal › Article
Future research directions in idiopathic pulmonary fibrosis: Summary of a National Heart, Lung, and Blood Institute Working Group
Crystal, R. G., Bitterman, P. B., Mossman, B., Schwarz, M. I., Sheppard, D., Almasy, L., Chapman, H. A., Friedman, S. L., King, T. E., Leinwand, L. A., Liotta, L., Martin, G. R., Schwartz, D. A., Schultz, G. S., Wagner, C. R. & Musson, R. A., Jul 15 2002, In : American journal of respiratory and critical care medicine. 166, 2, p. 236-246 11 p.Research output: Contribution to journal › Article
Hamster Monomorphic Arylamine N-Acetyltransferase: Expression in Escherichia coli and Purification
Bergstrom, C. P., Wagner, C. R., Ann, D. K. & Hanna, P. E., Feb 1 1995, In : Protein Expression and Purification. 6, 1, p. 45-55 11 p.Research output: Contribution to journal › Article
HINT1 protein: A new therapeutic target to enhance opioid antinociception and block mechanical allodynia
Garzón, J., Herrero-Labrador, R., Rodríguez-Muñoz, M., Shah, R., Vicente-Sánchez, A., Wagner, C. R. & Sánchez-Blázquez, P., Feb 2015, In : Neuropharmacology. 89, p. 412-423 12 p.Research output: Contribution to journal › Article
Human arylamine N-acetyltransferase 1: In vitro and intracellular inactivation by nitrosoarene metabolites of toxic and carcinogenic arylamines
Liu, L., Wagner, C. R. & Hanna, P. E., Oct 1 2008, In : Chemical research in toxicology. 21, 10, p. 2005-2016 12 p.Research output: Contribution to journal › Article
Identification of the amino acid-AZT-phosphoramidase by affinity T7 phage display selection
Cheng, J., Zhou, X., Chou, T. F., Ghosh, B., Liu, B. & Wagner, C. R., Dec 8 2009, In : Bioorganic and Medicinal Chemistry Letters. 19, 22, p. 6379-6381 3 p.Research output: Contribution to journal › Article
Impact of the C-terminal loop of histidine triad nucleotide binding protein 1 (Hint1) on substrate specificity
Chou, T. F., Sham, Y. Y. & Wagner, C. R., Nov 13 2007, In : Biochemistry. 46, 45, p. 13074-13079 6 p.Research output: Contribution to journal › Article
Induction of the p53 tumor suppressor in cancer cells through inhibition of cap-dependent translation
Harris, B. R. E., Wang, D., Zhang, Y., Ferrari, M., Okon, A., Cleary, M. P., Wagner, C. R. & Yang, D., May 1 2018, In : Molecular and cellular biology. 38, 10, e00367.Research output: Contribution to journal › Article
Inhibition by divalent metal ions of human histidine triad nucleotide binding protein1 (hHint1), a regulator of opioid analgesia and neuropathic pain
Shah, R., Chou, T. F., Maize, K. M., Strom, A., Finzel, B. C. & Wagner, C. R., Sep 23 2017, In : Biochemical and Biophysical Research Communications. 491, 3, p. 760-766 7 p.Research output: Contribution to journal › Article
Inhibition of CMP-sialic acid transport into golgi vesicles by nucleoside monophosphates
Chiaramonte, M., Koviach, J. L., Moore, C., Iyer, V. V., Wagner, C. R., Halcomb, R. L., Miller, W., Melançon, P. & Kuchta, R. D., Nov 27 2001, In : Biochemistry. 40, 47, p. 14260-14267 8 p.Research output: Contribution to journal › Article
Inhibition of HINT1 Modulates Spinal Nociception and NMDA Evoked Behavior in Mice
Shah, R. M., Peterson, C., Strom, A., Dillenburg, M., Finzel, B., Kitto, K. F., Fairbanks, C., Wilcox, G. & Wagner, C. R., Oct 16 2019, In : ACS Chemical Neuroscience. 10, 10, p. 4385-4393 9 p.Research output: Contribution to journal › Article
In vivo evaluation of site-specifically PEGylated chemically self-assembled protein nanostructures
Shah, R., Petersburg, J., Gangar, A. C., Fegan, A., Wagner, C. R. & Kumarapperuma, S. C., Jul 5 2016, In : Molecular Pharmaceutics. 13, 7, p. 2193-2203 11 p.Research output: Contribution to journal › Article
Irreversible inactivation of arylamine N-acetyltransferases in the presence of N-hydroxy-4-acetylaminobiphenyl: A comparison of human and hamster enzymes
Wang, H., Wagner, C. R. & Hanna, P. E., Feb 1 2005, In : Chemical research in toxicology. 18, 2, p. 183-197 15 p.Research output: Contribution to journal › Article
Isoform-selective inactivation of human arylamine N-acetyltransferases by reactive metabolites of carcinogenic arylamines
Liu, L., Wagner, C. R. & Hanna, P. E., Dec 21 2009, In : Chemical research in toxicology. 22, 12, p. 1962-1974 13 p.Research output: Contribution to journal › Article
Kinetic mechanism of human histidine triad nucleotide binding protein 1
Zhou, X., Chou, T. F., Aubol, B. E., Park, C. J., Wolfenden, R., Adams, J. & Wagner, C. R., May 21 2013, In : Biochemistry. 52, 20, p. 3588-3600 13 p.Research output: Contribution to journal › Article
Lysyl-tRNA synthetase-generated lysyl-adenylate is a substrate for histidine triad nucleotide binding proteins
Chou, T. F. & Wagner, C. R., Feb 16 2007, In : Journal of Biological Chemistry. 282, 7, p. 4719-4727 9 p.Research output: Contribution to journal › Article
Mass Spectrometric Investigation of the Mechanism of Inactivation of Hamster Arylamine N-Acetyltransferase 1 by N-Hydroxy-2-Acetylaminofluorene
Guo, Z., Wagner, C. R. & Hanna, P. E., Mar 1 2004, In : Chemical research in toxicology. 17, 3, p. 275-286 12 p.Research output: Contribution to journal › Article
Molecular Basis for Nonadditive Mutational Effects in Escherichia coli Dihydrofolate Reductase
Wagner, C. R., Huang, Z., Singleton, S. F. & Benkovic, S. J., Jan 1 1995, In : Biochemistry. 34, 48, p. 15671-15680 10 p.Research output: Contribution to journal › Article
Molecular modeling of geometries, charge distributions, and binding energies of small, druglike molecules containing nitrogen heterocycles and exocyclic amino groups in the gas phase and in aqueous solution
White, B. R., Wagner, C. R., Trahlar, D. G. & Amin, E. A., Oct 14 2008, In : Journal of Chemical Theory and Computation. 4, 10, p. 1718-1732 15 p.Research output: Contribution to journal › Article
Monitoring the Intracellular Metabolism of Nucleoside Phosphoramidate Pronucleotides by 31P NMR
Kim, J., Drontle, D. P. & Wagner, C. R., Mar 26 2004, In : Nucleosides, Nucleotides and Nucleic Acids. 23, 1-2, p. 483-493 11 p.Research output: Contribution to journal › Article
Multivalent Ligand Binding to Cell Membrane Antigens: Defining the Interplay of Affinity, Valency, and Expression Density
Csizmar, C. M., Petersburg, J. R., Perry, T. J., Rozumalski, L., Hackel, B. J. & Wagner, C. R., Jan 9 2019, In : Journal of the American Chemical Society. 141, 1, p. 251-261 11 p.Research output: Contribution to journal › Article
NMR-based Model Reveals the Structural Determinants of Mammalian Arylamine N-Acetyltransferase Substrate Specificity
Zhang, N., Liu, L., Liu, F., Wagner, C. R., Hanna, P. E. & Walters, K. J., Oct 13 2006, In : Journal of Molecular Biology. 363, 1, p. 188-200 13 p.Research output: Contribution to journal › Article
Nonadditivity of Mutational Effects at the Folate Binding Site of Escherichia coli Dihydrofolate Reductase
Huang, Z., Wagner, C. R. & Benkovic, S. J., Sep 1 1994, In : Biochemistry. 33, 38, p. 11576-11585 10 p.Research output: Contribution to journal › Article
Nontoxic chemical interdiction of the epithelial-to-mesenchymal transition by targeting cap-dependent translation
Ghosh, B., Benyumov, A., Ghosh, P., Jia, Y., Avdulov, S. V., Dahlberg, P. S., Peterson, M., Smith, K., Polunovsky, V. A., Bitterman, P. B. & Wagner, C. R., May 15 2009, In : ACS Chemical Biology. 4, 5, p. 367-377 11 p.Research output: Contribution to journal › Article
Over-expression, purification, and characterization of recombinant human arylamine N-acetyltransferase 1
Wang, H., Vath, G. M., Kawamura, A., Bates, C. A., Sim, E., Hanna, P. E. & Wagner, C. R., Feb 1 2005, In : Protein Journal. 24, 2, p. 65-77 13 p.Research output: Contribution to journal › Article
Overexpression and large-scale purification of recombinant hamster polymorphic arylamine N-acetyltransferase as a dihydrofolate reductase fusion protein
Sticha, K. R. K., Sieg, C. A., Bergstrom, C. P., Hanna, P. E. & Wagner, C. R., Jan 1 1997, In : Protein Expression and Purification. 10, 1, p. 141-153 13 p.Research output: Contribution to journal › Article
Pharmacokinetics of amino acid phosphoramidate monoesters of zidovudine in rats
Song, H., Griesgraber, G. W., Wagner, C. R. & Zimmerman, C. L., May 2 2002, In : Antimicrobial agents and chemotherapy. 46, 5, p. 1357-1363 7 p.Research output: Contribution to journal › Article
Phospholipid autoxidation
Porter, N. A. & Wagner, C. R., Jan 1 1986, In : Advances in Free Radical Biology and Medicine. 2, 2, p. 283-323 41 p.Research output: Contribution to journal › Article
Phosphoramidate pronucleotides: A comparison of the phosphoramidase substrate specificity of human and Escherichia coli histidine triad nucleotide binding proteins
Chou, T. F., Baraniak, J., Kaczmarek, R., Zhou, X., Cheng, J., Ghosh, B. & Wagner, C. R., Mar 1 2007, In : Molecular pharmaceutics. 4, 2, p. 208-217 10 p.Research output: Contribution to journal › Article
Potent growth inhibitory activity of zidovudine on cultured human breast cancer cells and rat mammary tumors
Wagner, C. R., Ballato, G., Akanni, A. O., McIntee, E. J., Larson, R. S., Chang, S. L. & Abul-Hajj, Y. J., Jun 15 1997, In : Cancer Research. 57, 12, p. 2341-2345 5 p.Research output: Contribution to journal › Article
Probing the catalytic potential of the hamster arylamine N-acetyltransferase 2 catalytic triad by site-directed mutagenesis of the proximal conserved residue, Tyr190
Zhou, X., Zhang, N., Liu, L., Walters, K. J., Hanna, P. E. & Wagner, C. R., Dec 1 2009, In : FEBS Journal. 276, 23, p. 6928-6941 14 p.Research output: Contribution to journal › Article
Probing the Impact of the echinT C-Terminal Domain on Structure and Catalysis
Bardaweel, S., Pace, J., Chou, T. F., Cody, V. & Wagner, C. R., Dec 10 2010, In : Journal of Molecular Biology. 404, 4, p. 627-638 12 p.Research output: Contribution to journal › Article
Probing the mechanism of hamster arylamine N-acetyltransferase 2 acetylation by active site modification, site-directed mutagenesis, and pre-steady state and steady state kinetic studies
Wang, H., Vath, G. M., Gleason, K. J., Hanna, P. E. & Wagner, C. R., Jun 29 2004, In : Biochemistry. 43, 25, p. 8234-8246 13 p.Research output: Contribution to journal › Article
Probing the Molecular Basis of Resistance to Pyrimethamine by Site-Directed Mutagenesis
Wagner, C. R. & Benkovic, S. J., Jul 1 1992, In : Journal of Medicinal Chemistry. 35, 15, p. 2912-2915 4 p.Research output: Contribution to journal › Article
Programmable self-assembly of antibody-oligonucleotide conjugates as small molecule and protein carriers
Gangar, A., Fegan, A., Kumarapperuma, S. C. & Wagner, C. R., Feb 15 2012, In : Journal of the American Chemical Society. 134, 6, p. 2895-2897 3 p.Research output: Contribution to journal › Article
Pronucleotides: Toward the in vivo delivery of antiviral and anticancer nucleotides
Wagner, C. R., Iyer, V. V. & McIntee, E. J., Nov 9 2000, In : Medicinal Research Reviews. 20, 6, p. 417-451 35 p.Research output: Contribution to journal › Article
Prosthetic antigen receptors
Shen, J., Vallera, D. A. & Wagner, C. R., Aug 19 2015, In : Journal of the American Chemical Society. 137, 32, p. 10108-10111 4 p.Research output: Contribution to journal › Article
Protein interface remodeling in a chemically induced protein dimer
White, B. R., Carlson, J. C. T., Kerns, J. L. & Wagner, C. R., Jul 1 2012, In : Journal of Molecular Recognition. 25, 7, p. 393-403 11 p.Research output: Contribution to journal › Article
Reversible Re-programing of Cell-Cell Interactions
Gabrielse, K., Gangar, A., Kumar, N., Lee, J. C., Fegan, A., Shen, J. J., Li, Q., Vallera, D. & Wagner, C. R., May 12 2014, In : Angewandte Chemie - International Edition. 53, 20, p. 5112-5116 5 p.Research output: Contribution to journal › Article
Role of cathepsin A and lysosomes in the intracellular activation of novel antipapillomavirus agent GS-9191
Birkus, G., Kutty, N., Frey, C. R., Shribata, R., Chou, T., Wagner, C. R., McDermott, M. & Cihlar, T., May 1 2011, In : Antimicrobial agents and chemotherapy. 55, 5, p. 2166-2173 8 p.Research output: Contribution to journal › Article
Self-assembly of antibodies by chemical induction
Li, Q., Hapka, D., Chen, H., Vallera, D. A. & Wagner, C. R., Dec 15 2008, In : Angewandte Chemie - International Edition. 47, 52, p. 10179-10182 4 p.Research output: Contribution to journal › Article
Simultaneous dual protein labeling using a triorthogonal reagent
Rashidian, M., Kumarapperuma, S. C., Gabrielse, K., Fegan, A., Wagner, C. R. & Distefano, M. D., Nov 6 2013, In : Journal of the American Chemical Society. 135, 44, p. 16388-16396 9 p.Research output: Contribution to journal › Article
Site directed mutagenesis: a tool for enzyme mechanism dissection
Wagner, C. R. & Benkovic, S. J., Jan 1 1990, In : Trends in Biotechnology. 8, C, p. 263-270 8 p.Research output: Contribution to journal › Article
Small-molecule inhibition of oncogenic eukaryotic protein translation in mesothelioma cells
Chen, E. Z., Jacobson, B. A., Patel, M. R., Okon, A. M., Li, S., Xiong, K., Vaidya, A. J., Bitterman, P. B., Wagner, C. R. & Kratzke, R. A., Jan 1 2014, In : Investigational New Drugs. 32, 4, p. 598-603 6 p.Research output: Contribution to journal › Article
Structural characterization of human histidine triad nucleotide-binding protein 2, a member of the histidine triad superfamily
Maize, K. M., Wagner, C. R. & Finzel, B. C., Jul 1 2013, In : FEBS Journal. 280, 14, p. 3389-3398 10 p.Research output: Contribution to journal › Article
Structure and Functional Characterization of Human Histidine Triad Nucleotide-Binding Protein 1 Mutations Associated with Inherited Axonal Neuropathy with Neuromyotonia
Shah, R. M., Maize, K. M., West, H. T., Strom, A. M., Finzel, B. C. & Wagner, C. R., Aug 17 2018, In : Journal of Molecular Biology. 430, 17, p. 2709-2721 13 p.Research output: Contribution to journal › Article
Switch-on fluorescent/FRET probes to study human histidine triad nucleotide binding protein 1 (hHint1), a novel target for opioid tolerance and neuropathic pain
Shah, R., Zhou, A. & Wagner, C. R., Jan 1 2017, In : Organic and Biomolecular Chemistry. 15, 48, p. 10230-10237 8 p.Research output: Contribution to journal › Article
Synthesis, in vitro anti-breast cancer activity, and intracellular decomposition of amino acid methyl ester and alkyl amide phosphoramidate monoesters of 3'-azido-3'-deoxythymidine (AZT)
Iyer, V. V., Griesgraber, G. W., Radmer, M. R., McIntee, E. J. & Wagner, C. R., Jun 1 2000, In : Journal of Medicinal Chemistry. 43, 11, p. 2266-2274 9 p.Research output: Contribution to journal › Article
Synthesis and antiviral activity of amino acid carbamate derivatives of AZT
Chang, S. L., Griesgraber, G., Abraham, T. W., Garg, T., Song, H., Zimmerman, C. L. & Wagner, C. R., Jan 1 2000, In : Nucleosides, Nucleotides and Nucleic Acids. 19, 1-2, p. 87-100 14 p.Research output: Contribution to journal › Article