1986 …2020

Research output per year

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Research Output

2005

Synthesis and evaluation of potential inhibitors of eIF4E cap binding to 7-methyl GTP

Ghosh, P., Park, C., Peterson, M. S., Bitterman, P. B., Polunovsky, V. A. & Wagner, C. R., Apr 15 2005, In : Bioorganic and Medicinal Chemistry Letters. 15, 8, p. 2177-2180 4 p.

Research output: Contribution to journalArticle

31 Scopus citations
2006

Arylamine N-acetyltransferase Aggregation and Constitutive Ubiquitylation

Liu, F., Zhang, N., Zhou, X., Hanna, P. E., Wagner, C. R., Koepp, D. M. & Walters, K. J., Aug 18 2006, In : Journal of Molecular Biology. 361, 3, p. 482-492 11 p.

Research output: Contribution to journalArticle

32 Scopus citations

Characterization of a radiolabeled small molecule targeting leukocyte function-associated antigen-1 expression in lymphoma and leukemia

Poria, R. B., Norenberg, J. P., Anderson, T. L., Erion, J., Wagner, C. R., Arterburn, J. B. & Larson, R. S., Nov 20 2006, In : Cancer Biotherapy and Radiopharmaceuticals. 21, 5, p. 418-426 9 p.

Research output: Contribution to journalArticle

5 Scopus citations

Chemically controlled self-assembly of protein nanorings

Carlson, J. C. T., Jena, S. S., Flenniken, M., Chou, T. F., Siegel, R. A. & Wagner, C. R., Jun 14 2006, In : Journal of the American Chemical Society. 128, 23, p. 7630-7638 9 p.

Research output: Contribution to journalArticle

115 Scopus citations

NMR-based Model Reveals the Structural Determinants of Mammalian Arylamine N-Acetyltransferase Substrate Specificity

Zhang, N., Liu, L., Liu, F., Wagner, C. R., Hanna, P. E. & Walters, K. J., Oct 13 2006, In : Journal of Molecular Biology. 363, 1, p. 188-200 13 p.

Research output: Contribution to journalArticle

39 Scopus citations
2007

Arylamine N-acetyltransferase I

Minchin, R. F., Hanna, P. E., Dupret, J. M., Wagner, C. R., Rodrigues-Lima, F. & Butcher, N. J., Sep 11 2007, In : International Journal of Biochemistry and Cell Biology. 39, 11, p. 1999-2005 7 p.

Research output: Contribution to journalShort survey

59 Scopus citations

Arylamine N-acetyltransferases: Characterization of the substrate specificities and molecular interactions of environmental arylamines with human NAT1 and NAT2

Liu, L., Von Vett, A., Zhang, N., Walters, K. J., Wagner, C. R. & Hanna, P. E., Sep 1 2007, In : Chemical research in toxicology. 20, 9, p. 1300-1308 9 p.

Research output: Contribution to journalArticle

32 Scopus citations

Engineered monomeric human histidine triad nucleotide-binding protein 1 hydrolyzes fluorogenic acyl-adenylate and lysyl-tRNA synthetase-generated lysyl-adenylate

Chou, T. F., Tikh, I. B., Horta, B. A. C., Ghosh, B., De Alencastro, R. B. & Wagner, C. R., May 18 2007, In : Journal of Biological Chemistry. 282, 20, p. 15137-15147 11 p.

Research output: Contribution to journalArticle

28 Scopus citations

Evidence that Human Histidine Triad Nucleotide Binding Protein 3 (Hint3) is a Distinct Branch of the Histidine Triad (HIT) Superfamily

Chou, T. F., Cheng, J., Tikh, I. B. & Wagner, C. R., Nov 2 2007, In : Journal of Molecular Biology. 373, 4, p. 978-989 12 p.

Research output: Contribution to journalArticle

7 Scopus citations

Impact of the C-terminal loop of histidine triad nucleotide binding protein 1 (Hint1) on substrate specificity

Chou, T. F., Sham, Y. Y. & Wagner, C. R., Nov 13 2007, In : Biochemistry. 46, 45, p. 13074-13079 6 p.

Research output: Contribution to journalArticle

12 Scopus citations

Lysyl-tRNA synthetase-generated lysyl-adenylate is a substrate for histidine triad nucleotide binding proteins

Chou, T. F. & Wagner, C. R., Feb 16 2007, In : Journal of Biological Chemistry. 282, 7, p. 4719-4727 9 p.

Research output: Contribution to journalArticle

45 Scopus citations

Phosphoramidate pronucleotides: A comparison of the phosphoramidase substrate specificity of human and Escherichia coli histidine triad nucleotide binding proteins

Chou, T. F., Baraniak, J., Kaczmarek, R., Zhou, X., Cheng, J., Ghosh, B. & Wagner, C. R., Mar 1 2007, In : Molecular pharmaceutics. 4, 2, p. 208-217 10 p.

Research output: Contribution to journalArticle

60 Scopus citations
2008

A letter from the editors. RE: Impact factors

Amidon, G. L., Wagner, C. R. & Lee, K. D., Jul 1 2008, In : Molecular Pharmaceutics. 5, 4, 1 p.

Research output: Contribution to journalEditorial

Enzyme nanorings

Chou, T. F., So, C., White, B. R., Carlson, J. C. T., Sarikaya, M. & Wagner, C. R., Dec 23 2008, In : ACS nano. 2, 12, p. 2519-2525 7 p.

Research output: Contribution to journalArticle

34 Scopus citations

Expression, purification and characterization of recombinant mouse translation initiation factor eIF4E as a dihydrofolate reductase (DHFR) fusion protein

Ghosh, P., Cheng, J., Chou, T. F., Jia, Y., Avdulov, S., Bitterman, P. B., Polunovsky, V. A. & Wagner, C. R., Aug 1 2008, In : Protein Expression and Purification. 60, 2, p. 132-139 8 p.

Research output: Contribution to journalArticle

7 Scopus citations
23 Scopus citations
10 Scopus citations

Self-assembly of antibodies by chemical induction

Li, Q., Hapka, D., Chen, H., Vallera, D. A. & Wagner, C. R., Dec 15 2008, In : Angewandte Chemie - International Edition. 47, 52, p. 10179-10182 4 p.

Research output: Contribution to journalArticle

20 Scopus citations

Fluorescent tumour imaging of type I IGF receptor in vivo: comparison of antibody-conjugated quantum dots and small-molecule fluorophore

Zhang, H., Zeng, X., Li, Q., Gaillard-Kelly, M., Wagner, C. R. & Yee, D., Jul 7 2009, In : British Journal of Cancer. 101, 1, p. 71-79 9 p.

Research output: Contribution to journalArticle

45 Scopus citations

Identification of the amino acid-AZT-phosphoramidase by affinity T7 phage display selection

Cheng, J., Zhou, X., Chou, T. F., Ghosh, B., Liu, B. & Wagner, C. R., Dec 8 2009, In : Bioorganic and Medicinal Chemistry Letters. 19, 22, p. 6379-6381 3 p.

Research output: Contribution to journalArticle

11 Scopus citations

Isoform-selective inactivation of human arylamine N-acetyltransferases by reactive metabolites of carcinogenic arylamines

Liu, L., Wagner, C. R. & Hanna, P. E., Dec 21 2009, In : Chemical research in toxicology. 22, 12, p. 1962-1974 13 p.

Research output: Contribution to journalArticle

24 Scopus citations

Nontoxic chemical interdiction of the epithelial-to-mesenchymal transition by targeting cap-dependent translation

Ghosh, B., Benyumov, A., Ghosh, P., Jia, Y., Avdulov, S. V., Dahlberg, P. S., Peterson, M., Smith, K., Polunovsky, V. A., Bitterman, P. B. & Wagner, C. R., May 15 2009, In : ACS Chemical Biology. 4, 5, p. 367-377 11 p.

Research output: Contribution to journalArticle

61 Scopus citations

Probing the catalytic potential of the hamster arylamine N-acetyltransferase 2 catalytic triad by site-directed mutagenesis of the proximal conserved residue, Tyr190

Zhou, X., Zhang, N., Liu, L., Walters, K. J., Hanna, P. E. & Wagner, C. R., Dec 1 2009, In : FEBS Journal. 276, 23, p. 6928-6941 14 p.

Research output: Contribution to journalArticle

3 Scopus citations
2010

Chemically controlled protein assembly: Techniques and applications

Fegan, A., White, B., Carlson, J. C. T. & Wagner, C. R., Jun 9 2010, In : Chemical Reviews. 110, 6, p. 3315-3336 22 p.

Research output: Contribution to journalArticle

159 Scopus citations

Chemically self-assembled antibody nanorings (CSANs): Design and characterization of an anti-CD3 IgM biomimetic

Li, Q., So, C. R., Fegan, A., Cody, V., Sarikaya, M., Vallera, D. A. & Wagner, C. R., Dec 8 2010, In : Journal of the American Chemical Society. 132, 48, p. 17247-17257 11 p.

Research output: Contribution to journalArticle

50 Scopus citations

Design, synthesis and evaluation of analogs of initiation factor 4E (eIF4E) cap-binding antagonist Bn7-GMP

Jia, Y., Chiu, T. L., Amin, E. A., Polunovsky, V., Bitterman, P. B. & Wagner, C. R., Apr 1 2010, In : European Journal of Medicinal Chemistry. 45, 4, p. 1304-1313 10 p.

Research output: Contribution to journalArticle

31 Scopus citations

DHFR Fusion proteins for the cellular delivery of methotrexate labeled oligonucleotides

Fegan, A., Kumarapperuma, S. C. & Wagner, C. R., Dec 1 2010, 7th Annual Conference on Foundations of Nanoscience: Self-Assembled Architectures and Devices, FNANO 2010. p. 27-28 2 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Probing the Impact of the echinT C-Terminal Domain on Structure and Catalysis

Bardaweel, S., Pace, J., Chou, T. F., Cody, V. & Wagner, C. R., Dec 10 2010, In : Journal of Molecular Biology. 404, 4, p. 627-638 12 p.

Research output: Contribution to journalArticle

13 Scopus citations
2011

Chemically induced self-assembly of enzyme nanorings.

White, B. R., Li, Q. & Wagner, C. R., Sep 15 2011, In : Methods in molecular biology (Clifton, N.J.). 743, p. 17-26 10 p.

Research output: Contribution to journalArticle

E. coli Histidine triad nucleotide binding protein 1 (echint) is a catalytic regulator of d-alanine dehydrogenase (dada) activity in vivo

Bardaweel, S., Ghosh, B., Chou, T. F., Sadowsky, M. J. & Wagner, C. R., Jul 11 2011, In : PloS one. 6, 7, e20897.

Research output: Contribution to journalArticle

8 Scopus citations

Role of cathepsin A and lysosomes in the intracellular activation of novel antipapillomavirus agent GS-9191

Birkus, G., Kutty, N., Frey, C. R., Shribata, R., Chou, T., Wagner, C., McDermott, M. & Cihlar, T., May 1 2011, In : Antimicrobial agents and chemotherapy. 55, 5, p. 2166-2173 8 p.

Research output: Contribution to journalArticle

13 Scopus citations
2012

Blood-nanoparticle interactions and in Vivo biodistribution: Impact of surface peg and ligand properties

Shah, N. B., Vercellotti, G. M., White, J. G., Fegan, A., Wagner, C. R. & Bischof, J. C., Aug 6 2012, In : Molecular pharmaceutics. 9, 8, p. 2146-2155 10 p.

Research output: Contribution to journalArticle

84 Scopus citations

Cap-Dependent Translation Initiation Factor eIF4E: An Emerging Anticancer Drug Target

Jia, Y., Polunovsky, V., Bitterman, P. B. & Wagner, C. R., Jul 1 2012, In : Medicinal Research Reviews. 32, 4, p. 786-814 29 p.

Research output: Contribution to journalReview article

69 Scopus citations

Chemically self-assembled antibody nanostructures as potential drug carriers

Fegan, A., Kumarapperuma, S. C. & Wagner, C. R., Nov 5 2012, In : Molecular pharmaceutics. 9, 11, p. 3218-3227 10 p.

Research output: Contribution to journalArticle

16 Scopus citations

Programmable self-assembly of antibody-oligonucleotide conjugates as small molecule and protein carriers

Gangar, A., Fegan, A., Kumarapperuma, S. C. & Wagner, C. R., Feb 15 2012, In : Journal of the American Chemical Society. 134, 6, p. 2895-2897 3 p.

Research output: Contribution to journalArticle

11 Scopus citations

Protein interface remodeling in a chemically induced protein dimer

White, B. R., Carlson, J. C. T., Kerns, J. L. & Wagner, C. R., Jul 1 2012, In : Journal of Molecular Recognition. 25, 7, p. 393-403 11 p.

Research output: Contribution to journalArticle

Synthesis and evaluation of potential inhibitors of human and Escherichia coli histidine triad nucleotide binding proteins

Bardaweel, S. K., Ghosh, B. & Wagner, C. R., Jan 1 2012, In : Bioorganic and Medicinal Chemistry Letters. 22, 1, p. 558-560 3 p.

Research output: Contribution to journalArticle

2 Scopus citations
2013

A highly efficient catalyst for oxime ligation and hydrazone-oxime exchange suitable for bioconjugation

Rashidian, M., Mahmoodi, M. M., Shah, R., Dozier, J. K., Wagner, C. R. & Distefano, M. D., Mar 20 2013, In : Bioconjugate Chemistry. 24, 3, p. 333-342 10 p.

Research output: Contribution to journalArticle

83 Scopus citations

Distinct Translational Control in CD4+ T Cell Subsets

Bjur, E., Larsson, O., Yurchenko, E., Zheng, L., Gandin, V., Topisirovic, I., Li, S., Wagner, C. R., Sonenberg, N. & Piccirillo, C. A., May 1 2013, In : PLoS genetics. 9, 5, e1003494.

Research output: Contribution to journalArticle

36 Scopus citations

Kinetic mechanism of human histidine triad nucleotide binding protein 1

Zhou, X., Chou, T. F., Aubol, B. E., Park, C. J., Wolfenden, R., Adams, J. & Wagner, C. R., May 21 2013, In : Biochemistry. 52, 20, p. 3588-3600 13 p.

Research output: Contribution to journalArticle

16 Scopus citations

Simultaneous dual protein labeling using a triorthogonal reagent

Rashidian, M., Kumarapperuma, S. C., Gabrielse, K., Fegan, A., Wagner, C. R. & Distefano, M. D., Nov 6 2013, In : Journal of the American Chemical Society. 135, 44, p. 16388-16396 9 p.

Research output: Contribution to journalArticle

30 Scopus citations

Structural characterization of human histidine triad nucleotide-binding protein 2, a member of the histidine triad superfamily

Maize, K. M., Wagner, C. R. & Finzel, B. C., Jul 1 2013, In : FEBS Journal. 280, 14, p. 3389-3398 10 p.

Research output: Contribution to journalArticle

17 Scopus citations

Targeted delivery of antisense oligonucleotides by chemically self-assembled nanostructures

Gangar, A., Fegan, A., Kumarapperuma, S. C., Huynh, P., Benyumov, A. & Wagner, C. R., Sep 3 2013, In : Molecular Pharmaceutics. 10, 9, p. 3514-3518 5 p.

Research output: Contribution to journalArticle

6 Scopus citations
42 Scopus citations
2014

Cap-dependent translation initiation factor, eIF4E, is the target for Ouabain-mediated inhibition of HIF-1α

Cao, J., He, L., Lin, G., Hu, C., Dong, R., Zhang, J., Zhu, H., Hu, Y., Wagner, C. R., He, Q. & Yang, B., May 1 2014, In : Biochemical Pharmacology. 89, 1, p. 20-30 11 p.

Research output: Contribution to journalArticle

16 Scopus citations

Reversible Re-programing of Cell-Cell Interactions

Gabrielse, K., Gangar, A., Kumar, N., Lee, J. C., Fegan, A., Shen, J. J., Li, Q., Vallera, D. & Wagner, C. R., May 12 2014, In : Angewandte Chemie - International Edition. 53, 20, p. 5112-5116 5 p.

Research output: Contribution to journalArticle

17 Scopus citations

Small-molecule inhibition of oncogenic eukaryotic protein translation in mesothelioma cells

Chen, E. Z., Jacobson, B. A., Patel, M. R., Okon, A. M., Li, S., Xiong, K., Vaidya, A. J., Bitterman, P. B., Wagner, C. R. & Kratzke, R. A., Aug 2014, In : Investigational New Drugs. 32, 4, p. 598-603 6 p.

Research output: Contribution to journalArticle

11 Scopus citations