Projects per year
Personal profile
Expertise related to UN SDGs
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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The Fingerprint is created by mining the titles and abstracts of the person's research outputs and projects/funding awards to create an index of weighted terms from discipline-specific thesauri.
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Projects
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Chemical biology of Peptide Regulation of Opioid Receptor Function
Haskell-Luevano, C. & Portoghese, P. S.
5/1/20 → 2/28/25
Project: Research project
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Novel Melanocortin Receptor Probe Discovery
NIH Natl Inst of Diabetes/Dig/Kidney Dis
4/1/16 → 3/31/21
Project: Research project
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Discovery of Opioid Receptor Endogenous Allosteric Modul
Winston & Maxine Wallin Neuro Disc Fund
1/1/18 → 12/31/18
Project: Research project
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Defensins as Melanocortin Ligands
NIH Natl Inst of Diabetes/Dig/Kidney Dis
10/1/15 → 11/30/17
Project: Research project
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Defensins as Melanocortin Ligands
NIH Natl Inst of Diabetes/Dig/Kidney Dis
12/1/12 → 11/30/15
Project: Research project
Research output
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Discovery of Molecular Interactions of the Human Melanocortin-4 Receptor (hMC4R) Asp189 (D189) Amino Acid with the Endogenous G-Protein-Coupled Receptor (GPCR) Antagonist Agouti-Related Protein (AGRP) Provides Insights to AGRP's Inverse Agonist Pharmacology at the hMC4R
Ericson, M. D., Haslach, E. M., Schnell, S. M., Freeman, K. T., Xiang, Z. M., Portillo, F. P., Speth, R., Litherland, S. A. & Haskell-Luevano, C., Feb 3 2021, In: ACS Chemical Neuroscience. 12, 3, p. 542-556 15 p.Research output: Contribution to journal › Article › peer-review
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Multiresidue Tetrapeptide Substitutions Yield a 140-fold Selective Melanocortin-3 over Melanocortin-4 Receptor Agonist
Ericson, M. D., Shaikh, R., Larson, C. M., Freeman, K. T. & Haskell-Luevano, C., Jan 14 2021, In: ACS Medicinal Chemistry Letters. 12, 1, p. 115-120 6 p.Research output: Contribution to journal › Article › peer-review
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Comparative intracerebroventricular and intrathecal administration of a nanomolar macrocyclic melanocortin receptor agonist MDE6- 5-2c (c[Pro-His-DPhe-Arg-Trp-Dap-Ala-DPro]) decreases food intake in mice
Haskell-Luevano, C., Adank, D. N., Lunzer, M. M., Ericson, M. D., Koeperich, Z. M., Wilber, S. L. & Fleming, K. A., Oct 7 2020, In: ACS Chemical Neuroscience. 11, 19, p. 3051-3063 13 p.Research output: Contribution to journal › Article › peer-review
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Incorporation of Agouti-Related Protein (AgRP) Human Single Nucleotide Polymorphisms (SNPs) in the AgRP-Derived Macrocyclic Scaffold c[Pro-Arg-Phe-Phe-Asn-Ala-Phe- d Pro] Decreases Melanocortin-4 Receptor Antagonist Potency and Results in the Discovery of Melanocortin-5 Receptor Antagonists
Koerperich, Z. M., Ericson, M. D., Freeman, K. T., Speth, R. C., Pogozheva, I. D., Mosberg, H. I. & Haskell-Luevano, C., Mar 12 2020, In: Journal of medicinal chemistry. 63, 5, p. 2194-2208 15 p.Research output: Contribution to journal › Article › peer-review
2 Scopus citations -
Peptoid NPhe4in AGRP-Based c[Pro1-Arg2-Phe3-Phe4-Xxx5-Ala6-Phe7-DPro8] Scaffolds Maintain Mouse MC4R Antagonist Potency
Ericson, M. D., Freeman, K. T. & Haskell-Luevano, C., Oct 8 2020, In: ACS Medicinal Chemistry Letters. 11, 10, p. 1942-1948 7 p.Research output: Contribution to journal › Article › peer-review
2 Scopus citations