1997 …2025

Research output per year

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Research Output

2020

Progesterone and Breast Cancer: an NCI Workshop Report

Sathyamoorthy, N. & Lange, C. A., Feb 1 2020, In : Hormones and Cancer. 11, 1

Research output: Contribution to journalEditorial

Open Access
2019

Phosphorylated progesterone receptor isoforms mediate opposing stem cell and proliferative breast cancer cell fates

Truong, T. H., Dwyer, A. R., Diep, C. H., Hu, H., Hagen, K. M. & Lange, C. A., Jan 1 2019, In : Endocrinology. 160, 2, p. 430-446 17 p.

Research output: Contribution to journalArticle

Open Access
6 Scopus citations
2018

Cancer stem cell phenotypes in ER+ breast cancer models are promoted by PELP1/AIB1 complexes

Truong, T. H., Hu, H., Temiz, N. A., Hagen, K. M., Girard, B. J., Brady, N. J., Schwertfeger, K. L., Lange, C. A. & Ostrander, J. H., Apr 1 2018, In : Molecular Cancer Research. 16, 4, p. 707-719 13 p.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Deciphering Steroid Receptor Crosstalk in Hormone-Driven Cancers

Truong, T. H. & Lange, C. A., Dec 1 2018, In : Endocrinology. 159, 12, p. 3897-3907 11 p.

Research output: Contribution to journalArticle

Open Access
7 Scopus citations

NOTCH3 expression is linked to breast cancer seeding and distant metastasis

Leontovich, A. A., Jalalirad, M., Salisbury, J. L., Mills, L., Haddox, C., Schroeder, M., Tuma, A., Guicciardi, M. E., Zammataro, L., Gambino, M. W., Amato, A., Di Leonardo, A., McCubrey, J., Lange, C. A., Liu, M., Haddad, T., Goetz, M., Boughey, J., Sarkaria, J., Wang, L. & 3 others, Ingle, J. N., Galanis, E. & D'Assoro, A. B., Sep 4 2018, In : Breast Cancer Research. 20, 1, 105.

Research output: Contribution to journalArticle

Open Access
9 Scopus citations
5 Scopus citations

Taxol induces brk-dependent prosurvival phenotypes in TNBC cells through an AhR/GR/HIF-driven signaling axis

Anderson, T. M. R., Ma, S., Kerkvliet, C. P., Peng, Y., Helle, T. M., Krutilina, R. I., Raj, G. V., Cidlowski, J. A., Ostrander, J. H., Schwertfeger, K. L., Seagroves, T. N. & Lange, C. A., Nov 2018, In : Molecular Cancer Research. 16, 11, p. 1761-1772 12 p.

Research output: Contribution to journalArticle

Open Access
2017

Development of a test that measures real-time HER2 signaling function in live breast cancer cell lines and primary cells

Huang, Y., Burns, D. J., Rich, B. E., MacNeil, I. A., Dandapat, A., Soltani, S. M., Myhre, S., Sullivan, B. F., Lange, C. A., Furcht, L. T. & Laing, L. G., Mar 16 2017, In : BMC Cancer. 17, 1, 199.

Research output: Contribution to journalArticle

Open Access
6 Scopus citations

Editorial: Towards Improving the Science of Hormones and Cancer

Lange, C. A., Feb 1 2017, In : Hormones and Cancer. 8, 1

Research output: Contribution to journalEditorial

Open Access

Pathway-based discovery of genetic interactions in breast cancer

Wang, W., Xu, Z. Z., Costanzo, M., Boone, C., Lange, C. A. & Myers, C. L., Sep 2017, In : PLoS genetics. 13, 9, e1006973.

Research output: Contribution to journalArticle

11 Scopus citations

Posttranslationally modified progesterone receptors direct ligand-specific expression of breast cancer stem cell-associated gene programs

Knutson, T. P., Truong, T. H., Ma, S., Brady, N. J., Sullivan, M. E., Raj, G., Schwertfeger, K. & Lange, C. A., Apr 17 2017, In : Journal of Hematology and Oncology. 10, 1, 89.

Research output: Contribution to journalArticle

Open Access
17 Scopus citations
2016
9 Scopus citations

A functional signal profiling test for identifying a subset of HER2-negative breast cancers with abnormally amplified HER2 signaling activity

Huang, Y., Burns, D. J., Rich, B. E., MacNeil, I. A., Dandapat, A., Soltani, S. M., Myhre, S., Sullivan, B. F., Furcht, L. T., Lange, C. A., Hurvitz, S. A. & Laing, L. G., Jan 1 2016, In : Oncotarget. 7, 48, p. 78577-78590 14 p.

Research output: Contribution to journalArticle

2 Scopus citations

Breast tumor kinase (Brk/PTK6) is induced by HIF, glucocorticoid receptor, and PELP1-mediated stress signaling in triple-negative breast cancer

Regan Anderson, T. M., Ma, S. H., Raj, G. V., Cidlowski, J. A., Helle, T. M., Knutson, T. P., Krutilina, R. I., Seagroves, T. N. & Lange, C. A., Mar 15 2016, In : Cancer Research. 76, 6, p. 1653-1663 11 p.

Research output: Contribution to journalArticle

13 Scopus citations

Modifications to glucocorticoid and progesterone receptors alter cell fate in breast cancer

Leehy, K. A., Regan Anderson, T. M., Daniel, A. R., Lange, C. A. & Ostrander, J. H., Apr 2016, In : Journal of molecular endocrinology. 56, 3, p. R99-R114

Research output: Contribution to journalReview article

10 Scopus citations
11 Scopus citations

Tumour and cellular distribution of activated forms of PR in breast cancers: A novel immunohistochemical analysis of a large clinical cohort

Bonneterre, J., Bosq, J., Jamme, P., Valent, A., Gilles, E. M., Zukiwski, A. A., Fuqua, S. A. W., Lange, C. A. & O'Shaughnessy, J., Jul 2016, In : ESMO Open. 1, 4, e000072.

Research output: Contribution to journalArticle

6 Scopus citations
2015

Minireview: Deciphering the cellular functions of PELP1

Ravindranathan, P., Lange, C. A. & Raj, G. V., Sep 1 2015, In : Molecular Endocrinology. 29, 9, p. 1222-1229 8 p.

Research output: Contribution to journalReview article

6 Scopus citations

Progesterone action in breast, uterine, and ovarian cancers

Diep, C., Daniel, A. R., Mauro, L. J., Knutson, T. P. & Lange, C. A., Jan 13 2015, In : Journal of molecular endocrinology. 54, 2, p. R31-R53

Research output: Contribution to journalReview article

75 Scopus citations

Progesterone receptor-B enhances estrogen responsiveness of breast cancer cells via scaffolding PELP1-and estrogen receptor-containing transcription complexes

Daniel, A. R., Gaviglio, A. L., Knutson, T. P., Ostrander, J. H., D'Assoro, A. B., Ravindranathan, P., Peng, Y., Raj, G. V., Yee, D. & Lange, C. A., Jan 22 2015, In : Oncogene. 34, 4, p. 506-515 10 p.

Research output: Contribution to journalArticle

61 Scopus citations

Statement of principle

Cefalu, W. T., Nair, K. S., Seaquist, E. R., Zierath, J., Boulton, A. J. M., LeRoith, D., Harrell, R. M., Grunberger, G., Wartofsky, L., Gore, A. C., Wierman, M. E., Hammes, S. R., Lange, C. A. & Santen, R. J., Feb 1 2015, In : Hormones & cancer. 6, 1, 1 p.

Research output: Contribution to journalEditorial

2014

Aurora-A mitotic kinase induces endocrine resistance through down-regulation of ERα expression in initially ERα+ breast cancer cells

Opyrchal, M., Salisbury, J. L., Zhang, S., McCubrey, J., Hawse, J., Goetz, M. P., Lomberk, G. A., Haddad, T., Degnim, A., Lange, C., Ingle, J. N., Galanis, E. & D'Assoro, A. B., May 9 2014, In : PloS one. 9, 5, e96995.

Research output: Contribution to journalArticle

13 Scopus citations

Hormones and Cancer is Alive and Well at ICE/ENDO 2014

Lange, C. A., Jun 2014, In : Hormones and Cancer. 5, 3, p. 125-126 2 p.

Research output: Contribution to journalEditorial

Lost in Translation: Can We Afford to Miss the Trees for the Forest?

Hammes, S. R. & Lange, C. A., Aug 2014, In : Hormones and Cancer. 5, 4, p. 203-206 4 p.

Research output: Contribution to journalEditorial

1 Scopus citations

Molecular determinants of context-dependent progesterone receptor action in breast cancer

Hagan, C. R. & Lange, C. A., Feb 20 2014, In : BMC medicine. 12, 1, 32.

Research output: Contribution to journalReview article

43 Scopus citations

Molecular determinants of context-dependent progesterone receptor action in breast cancer

Hagan, C. R. & Lange, C. A., Jan 1 2014, Cancer Cell Signaling: Targeting Signaling Pathways Toward Therapeutic Approaches to Cancer. Apple Academic Press, p. 231-252 22 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

PELP1: A review of PELP1 interactions, signaling, and biology

Girard, B. J., Daniel, A. R., Lange, C. A. & Ostrander, J. H., Jan 25 2014, In : Molecular and Cellular Endocrinology. 382, 1, p. 642-651 10 p.

Research output: Contribution to journalReview article

25 Scopus citations

Progesterone receptor-cyclin D1 complexes induce cell cycle-dependent transcriptional programs in breast cancer cells

Dressing, G. E., Knutson, T. P., Schiewer, M. J., Daniel, A. R., Hagan, C. R., Diep, C. H., Knudsen, K. E. & Lange, C. A., 2014, In : Molecular Endocrinology. 28, 4, p. 442-457 16 p.

Research output: Contribution to journalArticle

21 Scopus citations

Progesterone regulation of tissue factor depends on MEK1/2 activation and requires the proline-rich site on progesterone receptor

Bravo, M. L., Pinto, M. P., Gonzalez, I., Oliva, B., Kato, S., Cuello, M. A., Lange, C. A. & Owen, G. I., Jan 1 2014, In : Endocrine. 48, 1, p. 309-320 12 p.

Research output: Contribution to journalArticle

4 Scopus citations

Reprint of: Policy decisions on endocrine disruptors should be based on science across disciplines: A response to Dietrich, et al.

Gore, A. C., Balthazart, J., Bikle, D., Carpenter, D. O., Crews, D., Czernichow, P., Diamanti-Kandarakis, E., Dores, R. M., Grattan, D., Hof, P. R., Hollenberg, A. N., Lange, C., Lee, A. V., Levine, J. E., Millar, R. P., Nelson, R. J., Porta, M., Poth, M., Power, D. M., Prins, G. S. & 13 others, Ridgway, E. C., Rissman, E. F., Romijn, J. A., Sawchenko, P. E., Sly, P. D., Söder, O., Taylor, H. S., Tena-Sempere, M., Vaudry, H., Wallen, K., Wang, Z., Wartofsky, L. & Watson, C. S., Jan 1 2014, In : Frontiers in Neuroendocrinology. 35, 1, p. 2-5 4 p.

Research output: Contribution to journalEditorial

1 Scopus citations

Reprint of: Policy decisions on endocrine disruptors should be based on science across disciplines: A response to Dietrich et al.

Gore, A. C., Balthazart, J., Bikle, D., Carpenter, D. O., Crews, D., Czernichow, P., Diamanti-Kandarakis, E., Dores, R. M., Grattan, D., Hof, P. R., Hollenberg, A. N., Lange, C., Lee, A. V., Levine, J. E., Millar, R. P., Nelson, R. J., Porta, M., Poth, M., Power, D. M., Prins, G. S. & 13 others, Ridgway, E. C., Rissman, E. F., Romijn, J. A., Sawchenko, P. E., Sly, P. D., Söder, O., Taylor, H. S., Tena-Sempere, M., Vaudry, H., Wallen, K., Wang, Z., Wartofsky, L. & Watson, C. S., Feb 2014, In : Hormones and Behavior. 65, 2, p. 190-193 4 p.

Research output: Contribution to journalEditorial

3 Scopus citations

Statement of principle

Cefalu, W. T., Nair, K. S., Seaquist, E. R., Zierath, J., Boulton, A. J. M., LeRoith, D., Mack Harrell, R., Grunberger, G., Wartofsky, L., Gore, A. C., Wierman, M. E., Hammes, S. R., Lange, C. A. & Santen, R. J., Jan 1 2014, In : Endocrine reviews. 35, 6, 1 p.

Research output: Contribution to journalEditorial

Statement of principle

Cefalu, W. T., Nair, K. S., Seaquist, E. R., Zierath, J., Boulton, A. J. M., LeRoith, D., Harrell, R. M., Grunberger, G., Wartofsky, L., Gore, A. C., Wierman, M. E., Hammes, S. R., Lange, C. A. & Santen, R. J., Dec 1 2014, In : Journal of Clinical Endocrinology and Metabolism. 99, 12, 1 p.

Research output: Contribution to journalEditorial

1 Scopus citations

Tracking progesterone receptor-mediated actions in breast cancer

Knutson, T. P. & Lange, C. A., Apr 2014, In : Pharmacology and Therapeutics. 142, 1, p. 114-125 12 p.

Research output: Contribution to journalReview article

34 Scopus citations
2013
29 Scopus citations

Breast tumor kinase (Brk/PTK6) is a mediator of hypoxia- associated breast cancer progression

Anderson, T. M. R., Peacock, D. L., Daniel, A. R., Hubbard, G. K., Lofgren, K. A., Girard, B. J., Schorg, A., Hoogewijs, D., Wenger, R. H., Seagroves, T. N. & Lange, C. A., Sep 15 2013, In : Cancer Research. 73, 18, p. 5810-5820 11 p.

Research output: Contribution to journalArticle

26 Scopus citations

Dynamic Regulation of Steroid Hormone Receptor Transcriptional Activity by Reversible SUMOylation

Knutson, T. P. & Lange, C. A., 2013, Vitamins and Hormones. Academic Press Inc., p. 227-261 35 p. (Vitamins and Hormones; vol. 93).

Research output: Chapter in Book/Report/Conference proceedingChapter

7 Scopus citations

Policy decisions on endocrine disruptors should be based on science across disciplines: A response to Dietrich et al

Gore, A. C., Balthazart, J., Bikle, D., Carpenter, D. O., Crews, D., Czernichow, P., Diamanti-Kandarakis, E., Dores, R. M., Grattan, D., Hof, P. R., Hollenberg, A. N., Lange, C., Lee, A. V., Levine, J. E., Millar, R. P., Nelson, R. J., Porta, M., Poth, M., Power, D. M., Prins, G. S. & 13 others, Ridgway, E. C., Rissman, E. F., Romijn, J. A., Sawchenko, P. E., Sly, P. D., Söder, O., Taylor, H. S., Tena-Sempere, M., Vaudry, H., Wallen, K., Wang, Z., Wartofsky, L. & Watson, C. S., Nov 1 2013, In : Andrology. 1, 6, p. 802-805 4 p.

Research output: Contribution to journalLetter

Policy decisions on endocrine disruptors should be based on science across disciplines: A response to Dietrich et al.

Gore, A. C., Balthazart, J., Bikle, D., Carpenter, D. O., Crews, D., Czernichow, P., Diamanti-Kandarakis, E., Dores, R. M., Grattan, D., Hof, P. R., Hollenberg, A. N., Lange, C., Lee, A. V., Levine, J. E., Millar, R. P., Nelson, R. J., Porta, M., Poth, M., Power, D. M., Prins, G. S. & 13 others, Ridgway, E. C., Rissman, E. F., Romijn, J. A., Sawchenko, P. E., Sly, P. D., Söder, O., Taylor, H. S., Tena-Sempere, M., Vaudry, H., Wallen, K., Wang, Z., Wartofsky, L. & Watson, C. S., Dec 1 2013, In : European Journal of Endocrinology. 169, 6, p. E1-E4

Research output: Contribution to journalReview article

4 Scopus citations

Policy decisions on endocrine disruptors should be based on science across disciplines: A response to dietrich et al.

Gore, A. C., Balthazart, J., Bikle, D., Carpenter, D. O., Crews, D., Czernichow, P., Diamanti-Kandarakis, E., Dores, R. M., Grattan, D., Hof, P. R., Hollenberg, A. N., Lange, C., Lee, A. V., Levine, J. E., Millar, R. P., Nelson, R. J., Porta, M., Poth, M., Power, D. M., Prins, G. S. & 13 others, Ridgway, E. C., Rissman, E. F., Romijn, J. A., Sawchenko, P. E., Sly, P. D., Söder, O., Taylor, H. S., Tena-Sempere, M., Vaudry, H., Wallen, K., Wang, Z., Wartofsky, L. & Watson, C. S., Nov 1 2013, In : Hormone Research in Paediatrics. 80, 5, p. 305-308 4 p.

Research output: Contribution to journalReview article

1 Scopus citations

Policy decisions on endocrine disruptors should be based on science across disciplines: A response to Dietrich et al.

Gore, A. C., Balthazart, J., Bikle, D., Carpenter, D. O., Crews, D., Czernichow, P., Diamanti-Kandarakis, E., Dores, R. M., Grattan, D., Hof, P. R., Hollenberg, A. N., Lange, C., Lee, A. V., Levine, J. E., Millar, R. P., Nelson, R. J., Porta, M., Poth, M., Power, D. M., Prins, G. S. & 13 others, Ridgway, E. C., Rissman, E. F., Romijn, J. A., Sawchenko, P. E., Sly, P. D., Söder, O., Taylor, H. S., Tena-Sempere, M., Vaudry, H., Wallen, K., Wang, Z., Wartofsky, L. & Watson, C. S., Nov 1 2013, In : Endocrinology. 154, 11, p. 3957-3960 4 p.

Research output: Contribution to journalReview article

24 Scopus citations

Progesterone receptors induce FOXO1-dependent senescence in ovarian cancer cells

Diep, C. H., Charles, N. J., Gilks, C. B., Kalloger, S. E., Argenta, P. A. & Lange, C. A., May 1 2013, In : Cell Cycle. 12, 9, p. 1433-1449 17 p.

Research output: Contribution to journalArticle

44 Scopus citations

Updates from the Editors

Lange, C. A., Hankinson, S. E. & Tilley, W. D., Apr 23 2013, In : Hormones and Cancer. 4, 3, p. 121-122 2 p.

Research output: Contribution to journalEditorial

2012

Hormones and Cancer: A Bright Future

Lange, C. A., Apr 1 2012, In : Hormones and Cancer. 3, 1-2, p. 1-2 2 p.

Research output: Contribution to journalEditorial

Mechanisms of HGF/Met Signaling to Brk and Sam68 in Breast Cancer Progression

Locatelli, A., Lofgren, K. A., Daniel, A. R., Castro, N. E. & Lange, C. A., Apr 1 2012, In : Hormones and Cancer. 3, 1-2, p. 14-25 12 p.

Research output: Contribution to journalReview article

29 Scopus citations

Phosphorylated and sumoylation-deficient progesterone receptors drive proliferative gene signatures during breast cancer progression

Knutson, T. P., Daniel, A. R., Fan, D., Silverstein, K. A. T., Covington, K. R., Fuqua, S. A. W. & Lange, C. A., Jun 14 2012, In : Breast Cancer Research. 14, 3, R95.

Research output: Contribution to journalArticle

67 Scopus citations

Progesterone promotes focal adhesion formation and migration in breast cancer cells through induction of protease-activated receptor-1

Diaz, J., Aranda, E., Henriquez, S., Quezada, M., Espinoza, E., Bravo, M. L., Oliva, B., Lange, S., Villalon, M., Jones, M., Brosens, J. J., Kato, S., Cuello, M. A., Knutson, T. P., Lange, C. A., Leyton, L. & Owen, G. I., Aug 1 2012, In : Journal of Endocrinology. 214, 2, p. 165-175 11 p.

Research output: Contribution to journalArticle

19 Scopus citations

Role of phosphorylation in progesterone receptor signaling and specificity

Hagan, C. R., Daniel, A. R., Dressing, G. E. & Lange, C. A., Jun 24 2012, In : Molecular and Cellular Endocrinology. 357, 1-2, p. 43-49 7 p.

Research output: Contribution to journalReview article

42 Scopus citations
2011

ck2-dependent phosphorylation of progesterone receptors (PR) on ser81 regulates PR-B isoform-specific target gene expression in breast cancer cells

Hagan, C. R., Regan, T. M., Dressing, G. E. & Lange, C. A., Jun 1 2011, In : Molecular and cellular biology. 31, 12, p. 2439-2452 14 p.

Research output: Contribution to journalArticle

46 Scopus citations