Projects per year
Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Research Interest Keywords
- bacteria
- Klebsiella
- gram-negative bacteria
- immunology
- host-microbe interactions
- host-pathogen interactions
- bacteremia
- bloodstream infection
- Sepsis
- pneumonia
- Pulmonary Fibrosis
- neutrophils
- macrophages
- innate immunity
- Pathogenesis
Fingerprint
The Fingerprint is created by mining the titles and abstracts of the person's research outputs and projects/funding awards to create an index of weighted terms from discipline-specific thesauri.
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Collaborations and top research areas from the last five years
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Projects
- 1 Active
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Defining macrophage defense during Klebsiella pneumoniae bacteremia
Holmes, C. (PI)
NIH NATIONAL INST OF ALLERGY & INFECT DI
6/11/25 → 5/31/27
Project: Research project
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Pathogenesis of gram-negative bacteremia
Holmes, C. L., Anderson, M. T., Mobley, H. L. T. & Bachman, M. A., 2021, In: Clinical microbiology reviews. 34, 2, e00234-20.Research output: Contribution to journal › Review article › peer-review
Open Access201 Scopus citations -
Klebsiella pneumoniae causes bacteremia using factors that mediate tissue-specific fitness and resistance to oxidative stress
Holmes, C. L., Wilcox, A. E., Forsyth, V., Smith, S. N., Moricz, B. S., Unverdorben, L. V., Mason, S., Wu, W., Zhao, L., Mobley, H. L. T. & Bachman, M. A., Jul 2023, In: PLoS pathogens. 19, 7 July, e1011233.Research output: Contribution to journal › Article › peer-review
Open Access21 Scopus citations -
Patterns of Klebsiella pneumoniae bacteremic dissemination from the lung
Holmes, C. L., Dailey, K. G., Hullahalli, K., Wilcox, A. E., Mason, S., Moricz, B. S., Unverdorben, L. V., Balazs, G. I., Waldor, M. K. & Bachman, M. A., Dec 2025, In: Nature communications. 16, 1, 785.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations -
Bloodstream infections: mechanisms of pathogenesis and opportunities for intervention
Holmes, C. L., Albin, O. R., Mobley, H. L. T. & Bachman, M. A., Apr 2025, In: Nature Reviews Microbiology. 23, 4, p. 210-224 15 p., e0242921.Research output: Contribution to journal › Review article › peer-review
45 Scopus citations -
The ADP-Heptose Biosynthesis Enzyme GmhB is a Conserved Gram-Negative Bacteremia Fitness Factor
Holmes, C. L., Smith, S. N., Gurczynski, S. J., Severin, G. B., Unverdorben, L. V., Vornhagen, J., Mobley, H. L. T. & Bachman, M. A., Jul 2022, In: Infection and immunity. 90, 7Research output: Contribution to journal › Article › peer-review
Open Access15 Scopus citations