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Burckhard Seelig

19972021
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Fingerprint The Fingerprint is created by mining the titles and abstracts of the person's research outputs and projects/funding awards to create an index of weighted terms from discipline-specific thesauri.

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Projects 2009 2021

Evolvability of proteins and the emergence of new functions

Seelig, B.

Nat'l Aeronautics & Space Admin. (NASA)

6/15/18 → 6/14/21

Project: Research project

Protein

Generating and understanding de novo enzyme functionalit

Seelig, B.

Human Frontier Science Program

10/1/17 → 9/30/20

Project: Research project

enzymes
proteins

Evolution of Primordial Peptides, Proteins and the Genet

Seelig, B.

Simons Foundation

4/1/15 → 3/31/20

Project: Research project

genetic code
peptides
proteins

Developing Methods to Engineer Therapeutic Proteases

Seelig, B.

NIH Nat'l Inst of Allergy & Infect Dis

1/5/15 → 12/31/18

Project: Research project

Peptide Hydrolases
Therapeutics

Developing a synthetic evolution approach to create de n

Seelig, B.

NIH NIGMS NATL INST OF GENERAL

8/1/14 → 4/30/19

Project: Research project

enzyme

Research Output 1997 2019

Genetic Code Evolution Investigated through the Synthesis and Characterisation of Proteins from Reduced-Alphabet Libraries

Newton, M. S., Morrone, D. J., Lee, K-H. & Seelig, B., Mar 15 2019, In : ChemBioChem. 20, 6, p. 846-856 11 p.

Research output: Contribution to journal › Article

Genetic Code
Molecular Evolution
Libraries
Amino Acids
Proteins
3 Citations (Scopus)

ZFN, TALEN and CRISPR-Cas9 mediated homology directed gene insertion in Arabidopsis: A disconnect between somatic and germinal cells

Shan, Q., Baltes, N. J., Atkins, P. A., Kirkland, E. R., Zhang, Y., Baller, J. A., Lowder, L. G., Malzahn, A. A., Haugner, J. C., Seelig, B., Voytas, D. F. & Qi, Y., Dec 20 2018, In : Journal of Genetics and Genomics. 45, 12, p. 681-684 4 p.

Research output: Contribution to journal › Letter

Clustered Regularly Interspaced Short Palindromic Repeats
Insertional Mutagenesis
Arabidopsis
Transcription Activator-Like Effector Nucleases
1 Citation (Scopus)

Extensive libraries of gene truncation variants generated by in vitro transposition

Morelli, A., Cabezas, Y., Mills, L. J. & Seelig, B., Jan 1 2017, In : Nucleic acids research. 45, 10, e78.

Research output: Contribution to journal › Article

Open Access
Gene Library
Libraries
Nucleic Acids
Amino Acids
Enzymes

Multifunctional enzymes from reduced genomes – model proteins for simple primordial metabolism?

Seelig, B., Aug 1 2017, In : Molecular Microbiology. 105, 4, p. 505-507 3 p.

Research output: Contribution to journal › Comment/debate

Multifunctional Enzymes
Genome
Enzymes
Proteins
Metabolic Networks and Pathways
1 Citation (Scopus)

Highly efficient recombinant production and purification of streptococcal cysteine protease streptopain with increased enzymatic activity

Lane, M. D. & Seelig, B., May 1 2016, In : Protein Expression and Purification. 121, p. 66-72 7 p.

Research output: Contribution to journal › Article

streptopain
Cysteine Proteases
Streptococcus pyogenes
Virulence Factors
Proteins