1982 …2020

Research output per year

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Research Output

2009

Engineering lymphocyte subsets: Tools, trials and tribulations

June, C. H., Blazar, B. R. & Riley, J. L., Oct 1 2009, In : Nature Reviews Immunology. 9, 10, p. 704-716 13 p.

Research output: Contribution to journalReview article

158 Scopus citations

Expression of telomerase and telomere length are unaffected by either age or limb regeneration in Danio rerio

Lund, T. C., Glass, T. J., Tolar, J. & Blazar, B. R., Nov 6 2009, In : PloS one. 4, 11, e7688.

Research output: Contribution to journalArticle

37 Scopus citations

Ex vivo expanded non-human primate regulatory t cells suppress xeno-antigenic responses through both cytokine-and contact-dependent pathways

Johnson, J. L., Hennessy, E. A., Pahuja, A., Graham, M., Blazar, B. R., Hering, B. J. & Bansal-Pakala, P., 2009, In : Xenotransplantation. 16, 5, p. 387 1 p.

Research output: Contribution to journalArticle

Ex vivo inhibition of NF-κB signaling in alloreactive T-cells prevents graft-versus-host disease

O'Shaughnessy, M. J., Vogtenhuber, C., Sun, K., Sitcheran, R., Baldwin, A. S., Murphy, W. J., Dang, L., Jaffee, B., Palmer, E., Serody, J. S. & Blazar, B. R., Mar 1 2009, In : American Journal of Transplantation. 9, 3, p. 452-462 11 p.

Research output: Contribution to journalArticle

14 Scopus citations
5 Scopus citations

Genetic trickery - Escape of leukemia from immune attack

Barrett, J. & Blazar, B. R., Jul 30 2009, In : New England Journal of Medicine. 361, 5, p. 524-525 2 p.

Research output: Contribution to journalEditorial

5 Scopus citations

Human T Regulatory Cell Therapy: Take a Billion or So and Call Me in the Morning

Riley, J. L., June, C. H. & Blazar, B. R., May 22 2009, In : Immunity. 30, 5, p. 656-665 10 p.

Research output: Contribution to journalReview article

318 Scopus citations

IL-21 blockade reduces graft-versus-host disease mortality by supporting inducible T regulatory cell generation

Bucher, C., Koch, L., Vogtenhuber, C., Goren, E., Munger, M., Panoskaltsis-Mortari, A., Sivakumar, P. & Blazar, B. R., Dec 17 2009, In : Blood. 114, 26, p. 5375-5384 10 p.

Research output: Contribution to journalArticle

102 Scopus citations
36 Scopus citations

Inactivation of the adenosine A2A receptor protects apolipoprotein E-deficient mice from atherosclerosis

Wang, H., Zhang, W., Zhu, C., Bucher, C., Blazar, B. R., Zhang, C., Chen, J. F., Linden, J., Wu, C. & Huo, Y., Jul 1 2009, In : Arteriosclerosis, thrombosis, and vascular biology. 29, 7, p. 1046-1052 7 p.

Research output: Contribution to journalArticle

49 Scopus citations

Inducing the tryptophan catabolic pathway, indoleamine 2,3-dioxygenase (IDO), for suppression of graft-versus-host disease (GVHD) lethality

Koch, L. K., Bucher, C., Panoskaltsis-Mortari, A., Mellor, A. L., Munn, D. H. & Blazar, B. R., Dec 3 2009, In : Blood. 114, 24, p. 5062-5070 9 p.

Research output: Contribution to journalArticle

98 Scopus citations

In vitro differentiated TH17 cells mediate lethal acute graft-versus-host disease with severe cutaneous and pulmonary pathologic manifestations

Carlson, M. J., West, M. L., Coghill, J. M., Panoskaltsis-Mortari, A., Blazar, B. R. & Serody, J. S., Feb 5 2009, In : Blood. 113, 6, p. 1365-1374 10 p.

Research output: Contribution to journalArticle

217 Scopus citations
16 Scopus citations

Multipotent adult progenitor cells can suppress graft-versus-host disease via prostaglandin E2 synthesis and only if localized to sites of allopriming

Highfill, S. L., Kelly, R. M., O'Shaughnessy, M. J., Zhou, Q., Xia, L., Panoskaltsis-Mortari, A., Taylor, P. A., Tolar, J. & Blazar, B. R., Nov 20 2009, In : Blood. 114, 3, p. 693-701 9 p.

Research output: Contribution to journalArticle

48 Scopus citations

Myeloablative hematopoietic cell transplantation for acute lymphoblastic leukemia: Analysis of graft sources and long-term outcome

Tomblyn, M. B., Arora, M., Baker, K. S., Blazar, B. R., Brunstein, C. G., Burns, L. J., Defor, T. E., Dusenbery, K. E., Kaufman, D. S., Kersey, J. H., MacMillan, M. L., McGlave, P. B., Miller, J. S., Orchard, P. J., Slungaard, A., Tomblyn, M. R., Vercellotti, G. M., Verneris, M. R., Wagner, J. E. & Weisdorf, D. J., Aug 1 2009, In : Journal of Clinical Oncology. 27, 22, p. 3634-3641 8 p.

Research output: Contribution to journalArticle

63 Scopus citations
99 Scopus citations

Pig embryonic pancreatic tissue as a source for transplantation in diabetes: Transient treatment with anti-LFA1, anti-CD48, and FTY720 enables long-term graft maintenance in mice with only mild ongoing immunosuppression

Tchorsh-Yutsis, D., Hecht, G., Aronovich, A., Shezen, E., Klionsky, Y., Rosen, C., Bitcover, R., Eventov-Friedman, S., Katchman, H., Cohen, S., Tal, O., Milstein, O., Yagita, H., Blazar, B. R. & Reisner, Y., Jul 1 2009, In : Diabetes. 58, 7, p. 1585-1594 10 p.

Research output: Contribution to journalArticle

24 Scopus citations

PKCθ is required for alloreactivity and GVHD but not for immune responses toward leukemia and infection in mice

Valenzuela, J. O., Iclozan, C., Hossain, M. S., Prlic, M., Hopewell, E., Bronk, C. C., Wang, J., Celis, E., Engelman, R. W., Blazar, B. R., Bevan, M. J., Waller, E. K., Yu, X. Z. & Beg, A. A., Dec 1 2009, In : Journal of Clinical Investigation. 119, 12, p. 3774-3786 13 p.

Research output: Contribution to journalArticle

56 Scopus citations

Promising Progression-Free Survival for Patients Low and Intermediate Grade Lymphoid Malignancies after Nonmyeloablative Umbilical Cord Blood Transplantation

Brunstein, C. G., Cantero, S., Cao, Q., Majhail, N., McClune, B., Burns, L. J., Tomblyn, M., Miller, J. S., Blazar, B. R., McGlave, P. B., Weisdorf, D. J. & Wagner, J. E., Feb 1 2009, In : Biology of Blood and Marrow Transplantation. 15, 2, p. 214-222 9 p.

Research output: Contribution to journalArticle

37 Scopus citations
213 Scopus citations
8 Scopus citations

Sleeping Beauty-Mediated Transposition in Stem Cells

Wilber, A., Tolar, J., Blazar, B. R., Verfaillie, C. M., Lakshmipathy, U., Kaufman, D. S. & McIvor, R. S., Apr 17 2009, Emerging Technology Platforms for Stem Cells. John Wiley & Sons, Inc., p. 341-362 22 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

172 Scopus citations
2008

CD28 costimulation is essential for human T regulatory expansion and function

Golovina, T. N., Mikheeva, T., Suhoski, M. M., Aqui, N. A., Tai, V. C., Shan, X., Liu, R., Balcarcel, R. R., Fisher, N., Levine, B. L., Carroll, R. G., Warner, N., Blazar, B. R., June, C. H. & Riley, J. L., Aug 15 2008, In : Journal of Immunology. 181, 4, p. 2855-2868 14 p.

Research output: Contribution to journalArticle

112 Scopus citations

Circulating anticoagulant glycosaminoglycans in mucopolysaccharidosis type I

Tolar, J., Orchard, P. J., Key, N. S. & Blazar, B. R., May 1 2008, In : Journal of Thrombosis and Haemostasis. 6, 5, p. 893-895 3 p.

Research output: Contribution to journalArticle

5 Scopus citations

Combination Therapy Using IL-2 and Anti-CD25 Results in Augmented Natural Killer Cell-Mediated Antitumor Responses

Hallett, W. H. D., Ames, E., Álvarez, M., Barao, I., Taylor, P. A., Blazar, B. R. & Murphy, W. J., Oct 1 2008, In : Biology of Blood and Marrow Transplantation. 14, 10, p. 1088-1099 12 p.

Research output: Contribution to journalArticle

33 Scopus citations

Cytotoxic T cells reactive to an immunodominant leukemia-associated antigen can be specifically primed and expanded by combining a specific priming step with nonspecific large-scale expansion

Ghosh, A., Wolenski, M., Klein, C., Welte, K., Blazar, B. R. & Sauer, M. G., Feb 1 2008, In : Journal of Immunotherapy. 31, 2, p. 121-131 11 p.

Research output: Contribution to journalArticle

12 Scopus citations

Dendritic cell programming by cytomegalovirus stunts naive T cell responses via the PD-L1/PD-1 pathway

Benedict, C. A., Loewendorf, A., Garcia, Z., Blazar, B. R. & Janssen, E. M., Apr 1 2008, In : Journal of Immunology. 180, 7, p. 4836-4847 12 p.

Research output: Contribution to journalArticle

66 Scopus citations

Effects of donor T-cell trafficking and priming site on graft-versus-host disease induction by naive and memory phenotype CD4 T cells

Anderson, B. E., Taylor, P. A., McNiff, J. M., Jain, D., Demetris, A. J., Panoskaltsis-Mortari, A., Ager, A., Blazar, B. R., Shlomchik, W. D. & Shlomchik, M. J., May 15 2008, In : Blood. 111, 10, p. 5242-5251 10 p.

Research output: Contribution to journalArticle

59 Scopus citations

Expanded nonhuman primate Tregs exhibit a unique gene expression signature and potently downregulate alloimmune responses

Anderson, A., Martens, C. L., Hendrix, R., Stempora, L. L., Miller, W. P., Hamby, K., Russell, M., Strobert, E., Blazar, B. R., Pearson, T. C., Larsen, C. P. & Kean, L. S., Nov 1 2008, In : American Journal of Transplantation. 8, 11, p. 2252-2264 13 p.

Research output: Contribution to journalArticle

16 Scopus citations

Indoleamine 2,3-dioxygenase is a critical regulator of acute graft-versus-host disease lethality

Jasperson, L. K., Bucher, C., Panoskaltsis-Mortari, A., Taylor, P. A., Mellor, A. L., Munn, D. H. & Blazar, B. R., Mar 15 2008, In : Blood. 111, 6, p. 3257-3265 9 p.

Research output: Contribution to journalArticle

111 Scopus citations

Induction of transplantation tolerance by combining non-myeloablative conditioning with delivery of alloantigen by T cells

Tian, C., Yuan, X., Bagley, J., Blazar, B. R., Sayegh, M. H. & Iacomini, J., May 1 2008, In : Clinical Immunology. 127, 2, p. 130-137 8 p.

Research output: Contribution to journalArticle

8 Scopus citations

In situ identification of allospecific B cells using pentamers

Panoskaltsis-Mortari, A., Taylor, P. A., Riddle, M. J., Shlomchik, M. A. & R.Blazar, B., Apr 1 2008, In : Blood. 111, 7, p. 3904-3905 2 p.

Research output: Contribution to journalLetter

2 Scopus citations
71 Scopus citations
45 Scopus citations

Memory T cells in GVHD and GVL.

Anderson, B. E., Zheng, H., Taylor, P. A., Matte-Martone, C., McNiff, J. M., Jain, D., Demetris, A. J., Panoskaltsis-Mortari, A., Ager, A., Blazar, B. R., Shlomchik, M. J. & Shlomchik, W. D., Jan 2008, In : Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation. 14, 1 Suppl 1, p. 19-20 2 p.

Research output: Contribution to journalReview article

10 Scopus citations

Outgrowth of CD4low/negCD25+ T cells with suppressor function in CD4+CD25+ T cell cultures upon polyclonal stimulation ex vivo

Vogtenhuber, C., O'Shaughnessy, M. J., Vignali, D. A. A. & Blazar, B. R., Dec 15 2008, In : Journal of Immunology. 181, 12, p. 8767-8775 9 p.

Research output: Contribution to journalArticle

10 Scopus citations

Regulatory and conventional CD4+ T cells show differential effects correlating with PD-1 and B7-H1 expression after immunotherapy

Alderson, K. L., Zhou, Q., Berner, V., Wilkins, D. E. C., Weiss, J. M., Blazar, B. R., Welniak, L. A., Wiltrout, R. H., Redelman, D. & Murphy, W. J., Mar 1 2008, In : Journal of Immunology. 180, 5, p. 2981-2988 8 p.

Research output: Contribution to journalArticle

20 Scopus citations

Response: The role of G-CSF on the risk of graft-versus-host disease after donor lymphocyte infusions

Miller, J. S. & Blazar, B. R., May 15 2008, In : Blood. 111, 10, p. 5256-5257 2 p.

Research output: Contribution to journalLetter

Sleeping beauty transposon-mediated engineering of human primary T cells for therapy of CD19+ lymphoid malignancies

Huang, X., Guo, H., Kang, J., Choi, S., Zhou, T. C., Tammana, S., Lees, C. J., Li, Z. Z., Milone, M., Levine, B. L., Tolar, J., June, C. H., McIvor, R. S., Wagner, J. E., Blazar, B. R. & Zhou, X., Mar 2008, In : Molecular Therapy. 16, 3, p. 580-589 10 p.

Research output: Contribution to journalArticle

97 Scopus citations

Targeting of the CNS in MPS-IH using a nonviral transferrin-α-L-iduronidase fusion gene product

Osborn, M. J., McElmurry, R. T., Peacock, B., Tolar, J. & Blazar, B. R., Aug 1 2008, In : Molecular Therapy. 16, 8, p. 1459-1466 8 p.

Research output: Contribution to journalArticle

35 Scopus citations

The indoleamine 2,3-dioxygenase pathway is essential for human plasmacytoid dendritic cell-induced adaptive T regulatory cell generation

Chen, W., Liang, X., Peterson, A. J., Munn, D. H. & Blazar, B. R., Jan 1 2008, In : Journal of Immunology. 181, 8, p. 5396-5404 9 p.

Research output: Contribution to journalArticle

294 Scopus citations

Thymic stromal lymphopoietin is not necessary or sufficient to mediate the thymopoietic effects of keratinocyte growth factor [8]

Guimond, M., Leonard, W. J., Spolski, R., Rossi, S. W., Veenstra, R. G., Hollander, G. A., Mackall, C. L. & Blazar, B. R., Jan 15 2008, In : Blood. 111, 2, p. 969-970 2 p.

Research output: Contribution to journalLetter

4 Scopus citations

TLR agonists regulate alloresponses and uncover a critical role for donor APCs in allogeneic bone marrow rejection

Taylor, P. A., Ehrhardt, M. J., Lees, C. J., Panoskaltsis-Mortari, A., Krieg, A. M., Sharpe, A. H., Murphy, W. J., Serody, J. S., Hemmi, H., Akira, S., Levy, R. B. & Blazar, B. R., Oct 15 2008, In : Blood. 112, 8, p. 3508-3516 9 p.

Research output: Contribution to journalArticle

56 Scopus citations

Transgene expression and silencing in a tick cell line: A model system for functional tick genomics

Kurtti, T. J., Mattila, J. T., Herron, M. J., Felsheim, R. F., Baldridge, G. D., Burkhardt, N. Y., Blazar, B. R., Hackett, P. B., Meyer, J. M. & Munderloh, U. G., Oct 1 2008, In : Insect Biochemistry and Molecular Biology. 38, 10, p. 963-968 6 p.

Research output: Contribution to journalArticle

17 Scopus citations

Transient blockade of the inducible costimulator pathway generates long-term tolerance to factor VIII after nonviral gene transfer into hemophilia A mice

Peng, B., Ye, P., Blazar, B. R., Freeman, G. J., Rawlings, D. J., Ochs, H. D. & Miao, C. H., Sep 1 2008, In : Blood. 112, 5, p. 1662-1672 11 p.

Research output: Contribution to journalArticle

46 Scopus citations

Umbilical cord blood regulatory T-cell expansion and functional effects of tumor necrosis factor receptor family members OX40 and 4-1BB expressed on artificial antigen-presenting cells

Hippen, K. L., Harker-Murray, P., Porter, S. B., Merkel, S. C., Londer, A., Taylor, D. K., Bina, M., Panoskaltsis-Mortari, A., Rubinstein, P., Van Rooijen, N., Golovina, T. N., Suhoski, M. M., Miller, J. S., Wagner, J. E., June, C. H., Riley, J. L. & Blazar, B. R., Oct 1 2008, In : Blood. 112, 7, p. 2847-2857 11 p.

Research output: Contribution to journalArticle

109 Scopus citations
32 Scopus citations
2007

A new murine model for bronchiolitis obliterans post-bone marrow transplant

Panoskaltsis-Mortari, A., Tram, K. V., Price, A. P., Wendt, C. H. & Blazar, B. R., Oct 1 2007, In : American journal of respiratory and critical care medicine. 176, 7, p. 713-723 11 p.

Research output: Contribution to journalArticle

72 Scopus citations