1982 …2020

Research output per year

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Research Output

Article

Ligation of CD137 receptor prevents and reverses established anergy of CD8+ cytolytic T lymphocytes in vivo

Wilcox, R. A., Tamada, K., Flies, D. B., Zhu, G., Chapoval, A. I., Blazar, B. R., Kast, W. M. & Chen, L., Jan 1 2004, In : Blood. 103, 1, p. 177-184 8 p.

Research output: Contribution to journalArticle

74 Scopus citations

Ligation of OX40 (CD134) regulates graft-versus-host disease (GVHD) and graft rejection in allogeneic bone marrow transplant recipients

Blazar, B. R., Sharpe, A. H., Chen, A. I., Panoskaltsis-Mortari, A., Lees, C., Akiba, H., Yagita, H., Killeen, N. & Taylor, P. A., May 1 2003, In : Blood. 101, 9, p. 3741-3748 8 p.

Research output: Contribution to journalArticle

83 Scopus citations
32 Scopus citations

Lipid composition of whole brain and cerebellum in hurler syndrome (MPS IH) mice

Heinecke, K. A., Peacock, B. N., Blazar, B. R., Tolar, J. & Seyfried, T. N., Sep 1 2011, In : Neurochemical Research. 36, 9, p. 1669-1676 8 p.

Research output: Contribution to journalArticle

8 Scopus citations
47 Scopus citations

Long-term outcome of Hurler syndrome following bone marrow transplantation

Whitley, C. B., Belani, K. G., Chang, P. N., Summers, C. G., Blazar, B. R., Tsai, M. Y., Latchaw, R. E., Ramsay, N. K. C. & Kersey, J. H., Jan 1 1993, In : American Journal of Medical Genetics. 46, 2, p. 209-218 10 p.

Research output: Contribution to journalArticle

157 Scopus citations
Open Access
6 Scopus citations

Low-dose IL-2 selectively activates subsets of CD4+ Tregs and NK cells

Hirakawa, M., Matos, T. R., Liu, H., Koreth, J., Kim, H. T., Paul, N. E., Murase, K., Whangbo, J., Alho, A. C., Nikiforow, S., Cutler, C., Ho, V. T., Armand, P., Alyea, E. P., Antin, J. H., Blazar, B. R., Lacerda, J. F., Soiffer, R. J. & Ritz, J., Nov 3 2016, In : JCI insight. 1, 18, p. e89278

Research output: Contribution to journalArticle

Low-dose interleukin-2 therapy restores regulatory T cell homeostasis in patients with chronic graft-versus-host disease

Matsuoka, K. I., Koreth, J., Kim, H. T., Bascug, G., McDonough, S., Kawano, Y., Murase, K., Cutler, C., Ho, V. T., Alyea, E. P., Armand, P., Blazar, B. R., Antin, J. H., Soiffer, R. J. & Ritz, J., Apr 3 2013, In : Science Translational Medicine. 5, 179, 179ra43.

Research output: Contribution to journalArticle

259 Scopus citations

Low dose subcutaneous interleukin-2 after autologous transplantation generates sustained in vivo natural killer cell activity

Miller, J. S., Tessmer-Tuck, J., Pierson, B. A., Weisdorf, D., McGlave, P., Blazar, B. R., Katsanis, E., Verfaillie, C., Lebkowski, J., Radford, J. & Burns, L. J., Apr 1997, In : Biology of Blood and Marrow Transplantation. 3, 1, p. 34-44 11 p.

Research output: Contribution to journalArticle

73 Scopus citations

Low EGF in myeloablative allotransplantation: Association with severe acute GvHD in BMT CTN 0402

Holtan, S. G., Newell, L. F., Cutler, C., Verneris, M. R., Defor, T. E., Wu, J., Howard, A., Macmillan, M. L., Antin, J. H., Blazar, B. R., Weisdorf, D. J. & Panoskaltsis-Mortari, A., Sep 1 2017, In : Bone marrow transplantation. 52, 9, p. 1300-1303 4 p.

Research output: Contribution to journalArticle

Open Access
6 Scopus citations
4 Scopus citations

L-selectinhi but not the L-selectinlo CD4 +25+ T-regulatory cells are potent inhibitors of GVHD and BM graft rejection

Taylor, P. A., Panoskaltsis-Mortari, A., Swedin, J. M., Lucas, P. J., Gress, R. E., Levine, B. L., June, C. H., Serody, J. S. & Blazar, B. R., Dec 1 2004, In : Blood. 104, 12, p. 3804-3812 9 p.

Research output: Contribution to journalArticle

278 Scopus citations

L-selectin is dispensable for T regulatory cell function postallogeneic bone marrow transplantation

Carlson, M. J., Fulton, L. M., Coghill, J. M., West, M. L., Burgents, J. E., Wan, Y., Panoskaltsis-Mortari, A., Tedder, T. F., Blazar, B. R. & Serody, J. S., Dec 2010, In : American Journal of Transplantation. 10, 12, p. 2596-2603 8 p.

Research output: Contribution to journalArticle

7 Scopus citations

Lung parenchyma-derived IL-6 promotes IL-17A-dependent acute lung injury after allogeneic stem cell transplantation

Varelias, A., Gartlan, K. H., Kreijveld, E., Olver, S. D., Lor, M., Kuns, R. D., Lineburg, K. E., Teal, B. E., Raffelt, N. C., Cheong, M., Alexander, K. A., Koyama, M., Markey, K. A., Sturgeon, E., Leach, J., Reddy, P., Kennedy, G. A., Yanik, G. A., Blazar, B. R., Tey, S. K. & 4 others, Clouston, A. D., MacDonald, K. P. A., Cooke, K. R. & Hill, G. R., Apr 9 2015, In : Blood. 125, 15, p. 2435-2444 10 p.

Research output: Contribution to journalArticle

45 Scopus citations

Lymphodepletion followed by donor lymphocyte infusion (DLI) causes significantly more acute graft-versus-host disease than DLI alone

Miller, J. S., Weisdorf, D. J., Burns, L. J., Slungaard, A., Wagner, J. E., Verneris, M. R., Cooley, S., Wangen, R., Fautsch, S. K., Nicklow, R., DeFor, T. & Blazar, B. R., Oct 1 2007, In : Blood. 110, 7, p. 2761-2763 3 p.

Research output: Contribution to journalArticle

68 Scopus citations

mAbs to Bacillus anthracis capsular antigen for immunoprotection in anthrax and detection of antigenemia

Kozel, T. R., Murphy, W. J., Brandt, S., Blazar, B. R., Lovchik, J. A., Thorkildson, P., Percival, A. & Lyons, C. R., Apr 6 2004, In : Proceedings of the National Academy of Sciences of the United States of America. 101, 14, p. 5042-5047 6 p.

Research output: Contribution to journalArticle

86 Scopus citations

Maintenance of CD4 T cell fitness through regulation of Foxo1

Newton, R. H., Shrestha, S., Sullivan, J. M., Yates, K. B., Compeer, E. B., Ron-Harel, N., Blazar, B. R., Bensinger, S. J., Haining, W. N., Dustin, M. L., Campbell, D. J., Chi, H. & Turka, L. A., Aug 1 2018, In : Nature immunology. 19, 8, p. 838-848 11 p.

Research output: Contribution to journalArticle

Open Access
16 Scopus citations

Male donor-derived cells in the brains of female sex-mismatched bone marrow transplant recipients: A Y-chromosome specific in situ hybridization study

Unger, E. R., Sung, J. H., Manivel, J. C., Chenggis, M. L., Blazar, B. R. & Krivit, W., Sep 1993, In : Journal of neuropathology and experimental neurology. 52, 5, p. 460-470 11 p.

Research output: Contribution to journalArticle

147 Scopus citations

Massive ex vivo expansion of human natural regulatory T cells (T regs) with minimal loss of in vivo functional activity

Hippen, K. L., Merkel, S. C., Schirm, D. K., Sieben, C. M., Sumstad, D., Kadidlo, D. M., McKenna, D. H., Bromberg, J. S., Levine, B. L., Riley, J. L., June, C. H., Scheinberg, P., Douek, D. C., Miller, J. S., Wagner, J. E. & Blazar, B. R., May 18 2011, In : Science Translational Medicine. 3, 83, 83ra41.

Research output: Contribution to journalArticle

228 Scopus citations

Mechanisms of donor-specific transfusion tolerance: Preemptive induction of clonal T-cell exhaustion via indirect presentation

Quezada, S. A., Fuller, B., Jarvinen, L. Z., Gonzalez, M., Blazar, B. R., Rudensky, A. Y., Strom, T. B. & Noelle, R. J., Sep 1 2003, In : Blood. 102, 5, p. 1920-1926 7 p.

Research output: Contribution to journalArticle

86 Scopus citations

Mesenchymal cells isolated after acute lung injury manifest an enhanced proliferative phenotype

Chen, B., Polunovsky, V., White, J., Blazar, B., Nakhleh, R., Jessurun, J., Peterson, M. & Bitterman, P., 1992, In : Journal of Clinical Investigation. 90, 5, p. 1778-1785 8 p.

Research output: Contribution to journalArticle

46 Scopus citations
16 Scopus citations

Mesenchymal stromal cells shape the MDS microenvironment by inducing suppressive monocytes that dampen NK cell function

Sarhan, D., Wang, J., Arvindam, U. S., Hallstrom, C., Verneris, M. R., Grzywacz, B., Warlick, E., Blazar, B. R. & Miller, J. S., Mar 12 2020, In : JCI Insight. 5, 5, e130155.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Metabolic reprogramming augments potency of human pSTAT3-inhibited iTregs to suppress alloreactivity

Walton, K., Fernandez, M. R., Sagatys, E. M., Reff, J., Kim, J., Lee, M. C., Kiluk, J. V., Hui, J. Y. C., McKenna, D., Hupp, M., Forster, C., Linden, M. A., Lawrence, N. J., Lawrence, H. R., Pidala, J., Pavletic, S. Z., Blazar, B. R., Sebti, S. M., Cleveland, J. L., Anasetti, C. & 1 others, Betts, B. C., May 7 2020, In : JCI Insight. 5, 9, e136437.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

MHC Class II Antigen Presentation by the Intestinal Epithelium Initiates Graft-versus-Host Disease and Is Influenced by the Microbiota

Koyama, M., Mukhopadhyay, P., Schuster, I. S., Henden, A. S., Hülsdünker, J., Varelias, A., Vetizou, M., Kuns, R. D., Robb, R. J., Zhang, P., Blazar, B. R., Thomas, R., Begun, J., Waddell, N., Trinchieri, G., Zeiser, R., Clouston, A. D., Degli-Esposti, M. A. & Hill, G. R., Nov 19 2019, In : Immunity. 51, 5, p. 885-898.e7

Research output: Contribution to journalArticle

10 Scopus citations

Microbial translocation is a cause of systemic immune activation in chronic HIV infection

Brenchley, J. M., Price, D. A., Schacker, T. W., Asher, T. E., Silvestri, G., Rao, S., Kazzaz, Z., Bornstein, E., Lambotte, O., Altmann, D., Blazar, B. R., Rodriguez, B., Teixeira-Johnson, L., Landay, A., Martin, J. N., Hecht, F. M., Picker, L. J., Lederman, M. M., Deeks, S. G. & Douek, D. C., Dec 1 2006, In : Nature Medicine. 12, 12, p. 1365-1371 7 p.

Research output: Contribution to journalArticle

2323 Scopus citations

MicroRNA-155 modulates acute graft-versus-host disease by impacting T cell expansion, migration, and effector function

Zitzer, N. C., Snyder, K., Meng, X., Taylor, P. A., Efebera, Y. A., Devine, S. M., Blazar, B. R., Garzon, R. & Ranganathan, P., Jun 15 2018, In : Journal of Immunology. 200, 12, p. 4170-4179 10 p.

Research output: Contribution to journalArticle

Open Access
8 Scopus citations

MicroRNA-17-92 is required for T-cell and B-cell pathogenicity in chronic graft-versus-host disease in mice

Wu, Y., Schutt, S., Paz, K., Zhang, M., Flynn, R. P., Bastian, D., Hanief Sofi, M., Nguyen, H., Dai, M., Liu, C., Chang, Y. J., Blazar, B. R. & Yu, X. Z., Apr 26 2018, In : Blood. 131, 17, p. 1974-1986 13 p.

Research output: Contribution to journalArticle

Open Access
9 Scopus citations

MicroRNAs control the maintenance of thymic epithelia and their competence for T lineage commitment and thymocyte selection

Zuklys, S., Mayer, C. E., Zhanybekova, S., Stefanski, H. E., Nusspaumer, G., Gill, J., Barthlott, T., Chappaz, S., Nitta, T., Dooley, J., Nogales-Cadenas, R., Takahama, Y., Finke, D., Liston, A., Blazar, B. R., Pascual-Montano, A. & Hollände, G. A., Oct 15 2012, In : Journal of Immunology. 189, 8, p. 3894-3904 11 p.

Research output: Contribution to journalArticle

42 Scopus citations
71 Scopus citations

Minicircle DNA is superior to plasmid DNA in eliciting antigen-specific CD8 + T-cell responses

Dietz, W. M., Skinner, N. E. B., Hamilton, S. E., Jund, M. D., Heitfeld, S. M., Litterman, A. J., Hwu, P., Chen, Z. Y., Salazar, A. M., Ohlfest, J. R., Blazar, B. R., Pennell, C. A. & Osborn, M. J., Aug 2013, In : Molecular Therapy. 21, 8, p. 1526-1535 10 p.

Research output: Contribution to journalArticle

38 Scopus citations

Minimal PD-1 expression in mouse and human NK cells under diverse conditions

Judge, S. J., Dunai, C., Aguilar, E. G., Vick, S. C., Sturgill, I. R., Khuat, L. T., Stoffel, K. M., Van Dyke, J., Longo, D. L., Darrow, M. A., Anderson, S. K., Blazar, B. R., Monjazeb, A. M., Serody, J. S., Canter, R. J. & Murphy, W. J., Jun 1 2020, In : Journal of Clinical Investigation. 130, 6, p. 3051-3068 18 p.

Research output: Contribution to journalArticle

Open Access
6 Scopus citations

Minimum information about T regulatory cells: A step toward reproducibility and standardization

Fuchs, A., Gliwinski, M., Grageda, N., Spiering, R., Abbas, A. K., Appel, S., Bacchetta, R., Battaglia, M., Berglund, D., Blazar, B., Bluestone, J. A., Bornhäuser, M., Brinke, A. T., Brusko, T. M., Cools, N., Cuturi, M. C., Geissler, E., Giannoukakis, N., Golab, K., Hafler, D. A. & 41 others, van Ham, S. M., Hester, J., Hippen, K., Di Ianni, M., Ilic, N., Isaacs, J., Issa, F., Iwaszkiewicz-Grzes, D., Jaeckel, E., Joosten, I., Klatzmann, D., Koenen, H., Kooten, C. V., Korsgren, O., Kretschmer, K., Levings, M., Marek-Trzonkowska, N. M., Martinez-Llordella, M., Miljkovic, D., Mills, K. H. G., Miranda, J. P., Piccirillo, C. A., Putnam, A. L., Ritter, T., Roncarolo, M. G., Sakaguchi, S., Sánchez-Ramón, S., Sawitzki, B., Sofronic-Milosavljevic, L., Sykes, M., Tang, Q., Vives-Pi, M., Waldmann, H., Witkowski, P., Wood, K. J., Gregori, S., Hilkens, C. M. U., Lombardi, G., Lord, P., Martinez-Caceres, E. M. & Trzonkowski, P., Jan 15 2018, In : Frontiers in immunology. 8, JAN, 1844.

Research output: Contribution to journalArticle

Open Access
16 Scopus citations

miR-142-3p regulates autophagy by targeting ATG16L1 in thymic-derived regulatory T cell (tTreg)

Lu, Y., Gao, J., Zhang, S., Gu, J., Lu, H., Xia, Y., Zhu, Q., Qian, X., Zhang, F., Zhang, C., Shen, H., Hippen, K. L., Blazar, B. R., Lu, L. & Wang, X., Feb 19 2018, In : Cell death & disease. 9, 3, 1 p.

Research output: Contribution to journalArticle

Open Access
17 Scopus citations

MiR-146b antagomir-treated human Tregs acquire increased GVHD inhibitory potency

Lu, Y., Hippen, K. L., Lemire, A. L., Gu, J., Wang, W., Ni, X., Ranganathan, P., Levine, B. L., Riley, J. L., June, C. H., Turka, L. A., Munn, D. H., Garzon, R., Lu, L. & Blazar, B. R., Sep 8 2016, In : Blood. 128, 10, p. 1424-1435 12 p.

Research output: Contribution to journalArticle

Open Access
22 Scopus citations

miR-221 and miR-155 regulate human dendritic cell development, apoptosis, and IL-12 production through targeting of p27 kip1, KPC1, and SOCS-1

Lu, C., Huang, X., Zhang, X., Roensch, K., Cao, Q., Nakayama, K. I., Blazar, B. R., Zeng, Y. & Zhou, X., Apr 21 2011, In : Blood. 117, 16, p. 4293-4303 11 p.

Research output: Contribution to journalArticle

201 Scopus citations

Mitochondrial Integrity Regulated by Lipid Metabolism Is a Cell-Intrinsic Checkpoint for Treg Suppressive Function

Field, C. S., Baixauli, F., Kyle, R. L., Puleston, D. J., Cameron, A. M., Sanin, D. E., Hippen, K. L., Loschi, M., Thangavelu, G., Corrado, M., Edwards-Hicks, J., Grzes, K. M., Pearce, E. J., Blazar, B. R. & Pearce, E. L., Feb 4 2020, In : Cell Metabolism. 31, 2, p. 422-437.e5

Research output: Contribution to journalArticle

Open Access
9 Scopus citations

Modification of T cell responses by stem cell mobilization requires direct signaling of the T cell by G-CSF and IL-10

MacDonald, K. P. A., Le Texier, L., Zhang, P., Morris, H., Kuns, R. D., Lineburg, K. E., Leveque, L., Don, A. L., Markey, K. A., Vuckovic, S., Bagger, F. O., Boyle, G. M., Blazar, B. R. & Hill, G. R., Apr 1 2014, In : Journal of Immunology. 192, 7, p. 3180-3189 10 p.

Research output: Contribution to journalArticle

24 Scopus citations

Modulation of immune checkpoints and graft-versus-leukemia in allogeneic transplants by antagonizing vasoactive intestinal peptide signaling

Li, J. M., Petersen, C. T., Li, J. X., Panjwani, R., Chandra, D. J., Giver, C. R., Blazar, B. R. & Waller, E. K., Dec 1 2016, In : Cancer Research. 76, 23, p. 6802-6815 14 p.

Research output: Contribution to journalArticle

Open Access
6 Scopus citations
20 Scopus citations
4 Scopus citations

Monomeric annexin A2 is an oxygen-regulated toll-like receptor 2 ligand and adjuvant

Andersen, B. M., Xia, J., Epstein, A. L., Ohlfest, J. R., Chen, W., Blazar, B. R., Pennell, C. A. & Olin, M. R., Feb 16 2016, In : Journal for ImmunoTherapy of Cancer. 4, 1, 11.

Research output: Contribution to journalArticle

Open Access
9 Scopus citations

Mouse Ly49G2+ NK cells dominate early responses during both immune reconstitution and activation independently of MHC

Barao, I., Alvarez, M., Ames, E., Orr, M. T., Stefanski, H. E., Blazar, B. R., Lanier, L. L., Anderson, S. K., Redelman, D. & Murphy, W. J., Jun 30 2011, In : Blood. 117, 26, p. 7032-7041 10 p.

Research output: Contribution to journalArticle

33 Scopus citations

Multipotent adult progenitor cells can suppress graft-versus-host disease via prostaglandin E2 synthesis and only if localized to sites of allopriming

Highfill, S. L., Kelly, R. M., O'Shaughnessy, M. J., Zhou, Q., Xia, L., Panoskaltsis-Mortari, A., Taylor, P. A., Tolar, J. & Blazar, B. R., 2009, In : Blood. 114, 3, p. 693-701 9 p.

Research output: Contribution to journalArticle

48 Scopus citations

Murine chronic graft-versus-host disease proteome profiling discovers CCL15 as a novel biomarker in patients

Du, J., Flynn, R., Paz, K., Ren, H. G., Ogata, Y., Zhang, Q., Gafken, P. R., Storer, B. E., Roy, N. H., Burkhardt, J. K., Mathews, W., Tolar, J., Lee, S. J., Blazar, B. R. & Paczesny, S., Apr 12 2018, In : Blood. 131, 15, p. 1743-1754 12 p.

Research output: Contribution to journalArticle

Open Access
10 Scopus citations
60 Scopus citations

Murine γ/δ-expressing T cells affect alloengraftment via the recognition of nonclassical major histocompatibility complex class Ib antigens

Blazar, B. R., Taylor, P. A., Bluestone, J. A. & Vallera, D. A., May 15 1996, In : Blood. 87, 10, p. 4463-4472 10 p.

Research output: Contribution to journalArticle

Open Access
31 Scopus citations

Myeloablative hematopoietic cell transplantation for acute lymphoblastic leukemia: Analysis of graft sources and long-term outcome

Tomblyn, M. B., Arora, M., Baker, K. S., Blazar, B. R., Brunstein, C. G., Burns, L. J., Defor, T. E., Dusenbery, K. E., Kaufman, D. S., Kersey, J. H., MacMillan, M. L., McGlave, P. B., Miller, J. S., Orchard, P. J., Slungaard, A., Tomblyn, M. R., Vercellotti, G. M., Verneris, M. R., Wagner, J. E. & Weisdorf, D. J., Aug 1 2009, In : Journal of Clinical Oncology. 27, 22, p. 3634-3641 8 p.

Research output: Contribution to journalArticle

63 Scopus citations