1982 …2020

Research output per year

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Research Output

Article

161533 TriKE stimulates NK-cell function to overcome myeloid-derived suppressor cells in MDS

Sarhan, D., Brandt, L., Felices, M., Guldevall, K., Lenvik, T., Hinderlie, P., Curtsinger, J., Warlick, E., Spellman, S. R., Blazar, B. R., Weisdorf, D. J., Cooley, S., Vallera, D. A., Onfelt, B. & Miller, J. S., Jun 26 2018, In : Blood Advances. 2, 12, p. 1459-1469 11 p.

Research output: Contribution to journalArticle

Open Access
17 Scopus citations

4-1BB and CD28 signaling plays a synergistic role in redirecting umbilical cord blood t cells against b-cell malignancies

Tammana, S., Huang, X., Wong, M., Milone, M. C., Ma, L., Levine, B. L., June, C. H., Wagner, J. E., Blazar, B. R. & Zhou, X., Jan 1 2010, In : Human gene therapy. 21, 1, p. 75-86 12 p.

Research output: Contribution to journalArticle

97 Scopus citations

Abnormal function of the bone marrow microenvironment in chronic myelogenous leukemia: Role of malignant stromal macrophages

Bhatia, R., McGlave, P. B., Dewald, G. W., Blazar, B. R. & Verfaillie, C. M., Jan 1 1995, In : Blood. 85, 12, p. 3636-3645 10 p.

Research output: Contribution to journalArticle

154 Scopus citations

Abnormal T cell-dependent B-cell responses in SCID mice receiving allogeneic bone marrow in utero

Waldschmidt, T. J., Panoskaltsis-Mortari, A., Mc Elmurry, R. T., Tygrett, L. T., Taylor, P. A. & Blazar, B. R., Dec 15 2002, In : Blood. 100, 13, p. 4557-4564 8 p.

Research output: Contribution to journalArticle

19 Scopus citations

A Bortezomib-Based Regimen Offers Promising Survival and Graft-versus-Host Disease Prophylaxis in Myeloablative HLA-Mismatched and Unrelated Donor Transplantation: A Phase II Trial

Koreth, J., Kim, H. T., Lange, P. B., Bindra, B., Reynolds, C. G., Chammas, M. J., Armand, P., Cutler, C. S., Ho, V. T., Glotzbecker, B., Nikiforow, S., Ritz, J., Blazar, B. R., Soiffer, R. J., Antin, J. H. & Alyea, E. P., Nov 2015, In : Biology of Blood and Marrow Transplantation. 21, 11, p. 1907-1913 7 p.

Research output: Contribution to journalArticle

17 Scopus citations

Absence of a facilitory role for NK 1.1-positive donor cells in engraftment across a major histocompatibility barrier in mice

Blazar, B. R., Soderling, C. C. B., Koo, G. C. & Vallera, D. A., May 1988, In : Transplantation. 45, 5, p. 876-883 8 p.

Research output: Contribution to journalArticle

29 Scopus citations

Absence of host tumor necrosis factor receptor 1 attenuates manifestations of idiopathic pneumonia syndrome

Shukla, M., Yang, S., Milla, C., Panoskaltsis-Mortari, A., Blazar, B. R. & Haddad, I. Y., May 1 2005, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 288, 5 32-5, p. L942-L949

Research output: Contribution to journalArticle

19 Scopus citations

Acceleration of idiopathic pneumonia syndrome (IPS) in the absence of donor MIP-1α (CCL3) after allogeneic BMT in mice

Panoskaltsis-Mortari, A., Hermanson, J. R., Taras, E., Wangensteen, O. D., Serody, J. S. & Blazar, B. R., May 1 2003, In : Blood. 101, 9, p. 3714-3721 8 p.

Research output: Contribution to journalArticle

30 Scopus citations

A confirmation of chronic graft-versus-host disease prediction using allogeneic HY antibodies following sex-mismatched hematopoietic cell transplantation

Paul, J., Nakasone, H., Sahaf, B., Wu, F., Wang, K., Ho, V., Wu, J., Kim, H., Blazar, B., Ritz, J., Howard, A., Cutler, C. & Miklos, D., Jun 30 2019, In : Haematologica. 104, 7, p. e314-e317

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

A correlation between conditioning and engraftment in recipients of MHC-mismatched T cell-depleted murine bone marrow transplants

Soderling, C. C. B., Song, C. W., Blazar, B. R. & Vallera, D. A., Dec 1 1985, In : Journal of Immunology. 135, 2, p. 941-946 6 p.

Research output: Contribution to journalArticle

99 Scopus citations

A critical role for CD48 antigen in regulating alloengraftment and lymphohematopoietic recovery after bone marrow transplantation

Blazar, B. R., Taylor, P. A., Panoskaltsis-Mortari, A., Yagita, H., Bromberg, J. S. & Vallera, D. A., Dec 1 1998, In : Blood. 92, 11, p. 4453-4463 11 p.

Research output: Contribution to journalArticle

17 Scopus citations

A critical role for donor-derived IL-22 in cutaneous chronic GVHD

Gartlan, K. H., Bommiasamy, H., Paz, K., Wilkinson, A. N., Owen, M., Reichenbach, D. K., Banovic, T., Wehner, K., Buchanan, F., Varelias, A., Kuns, R. D., Chang, K., Fedoriw, Y., Shea, T., Coghill, J., Zaiken, M., Plank, M. W., Foster, P. S., Clouston, A. D., Blazar, B. R. & 2 others, Serody, J. S. & Hill, G. R., Apr 2018, In : American Journal of Transplantation. 18, 4, p. 810-820 11 p.

Research output: Contribution to journalArticle

Open Access
13 Scopus citations

Activated protein C ameliorates chronic graft-versus-host disease by PAR1-dependent biased cell signaling on T cells

Sinha, R. K., Flynn, R., Zaiken, M., Paz, K., Gavin, A. L., Nemazee, D., Fernández, J. A., Xu, X., Griffin, J. H. & Blazar, B. R., Aug 29 2019, In : Blood. 134, 9, p. 776-781 6 p.

Research output: Contribution to journalArticle

2 Scopus citations

Activation of p53 in Immature Myeloid Precursor Cells Controls Differentiation into Ly6c+CD103+ Monocytic Antigen-Presenting Cells in Tumors

Sharma, M. D., Rodriguez, P. C., Koehn, B. H., Baban, B., Cui, Y., Guo, G., Shimoda, M., Pacholczyk, R., Shi, H., Lee, E. J., Xu, H., Johnson, T. S., He, Y., Mergoub, T., Venable, C., Bronte, V., Wolchok, J. D., Blazar, B. R. & Munn, D. H., Jan 16 2018, In : Immunity. 48, 1, p. 91-106.e6

Research output: Contribution to journalArticle

Open Access
31 Scopus citations

Activation of thymic regeneration in mice and humans following androgen blockade

Sutherland, J. S., Goldberg, G. L., Hammett, M. V., Uldrich, A. P., Berzins, S. P., Heng, T. S., Blazar, B. R., Millar, J. L., Malin, M. A., Chidgey, A. P. & Boyd, R. L., Aug 15 2005, In : Journal of Immunology. 175, 4, p. 2741-2753 13 p.

Research output: Contribution to journalArticle

312 Scopus citations

Acute graft-versus-host disease: From the bench to the bedside

Socié, G. & Blazar, B. R., Nov 12 2009, In : Blood. 114, 20, p. 4327-4336 10 p.

Research output: Contribution to journalArticle

195 Scopus citations
147 Scopus citations

Acute graft-versus-host disease following unrelated donor marrow transplantation: Failure of conventional therapy

Roy, J., Mc Glave, P. B., Filipovich, A. H., Miller, W. J., Blazar, B. R., Ramsay, N. K., Kersey, J. H. & Weisdorf, D. J., Jan 1 1992, In : Bone marrow transplantation. 10, 1, p. 77-82 6 p.

Research output: Contribution to journalArticle

70 Scopus citations

Acute graft-versus-host disease is regulated by an IL-17–sensitive microbiome

Varelias, A., Ormerod, K. L., Bunting, M. D., Koyama, M., Gartlan, K. H., Kuns, R. D., Lachner, N., Locke, K. R., Lim, C. Y., Henden, A. S., Zhang, P., Clouston, A. D., Hasnain, S. Z., McGuckin, M. A., Blazar, B. R., MacDonald, K. P. A., Hugenholtz, P. & Hill, G. R., Apr 13 2017, In : Blood. 129, 15, p. 2172-2185 14 p.

Research output: Contribution to journalArticle

Open Access
34 Scopus citations

Acute upper gastrointestinal graft-versus-host disease: Clinical significance and response to immunosuppressive therapy

Weisdorf, D. J., Snover, D. C., Haake, R., Miller, W. J., McGlave, P. B., Blazar, B., Ramsey, N. K. C., Kersey, J. H. & Filipovich, A., Jan 1 1990, In : Blood. 76, 3, p. 624-629 6 p.

Research output: Contribution to journalArticle

141 Scopus citations
32 Scopus citations

Adaptive NK cell reconstitution is associated with better clinical outcomes

Cichocki, F., Taras, E., Chiuppesi, F., Wagner, J. E., Blazar, B. R., Brunstein, C., Luo, X., Diamond, D. J., Cooley, S., Weisdorf, D. J. & Miller, J. S., Jan 24 2019, In : JCI Insight. 4, 2, Y.

Research output: Contribution to journalArticle

Open Access
11 Scopus citations

Adaptive NK cells resist regulatory T-cell suppression driven by IL37

Sarhan, D., Hippen, K. L., Lemire, A., Hying, S., Luo, X., Lenvik, T., Curtsinger, J., Davis, Z., Zhang, B., Cooley, S., Cichocki, F., Blazar, B. R. & Miller, J. S., Jul 2018, In : Cancer Immunology Research. 6, 7, p. 766-775 10 p.

Research output: Contribution to journalArticle

Open Access
17 Scopus citations

Adaptive NK cells with low TIGIT expression are inherently resistant to myeloid-derived suppressor cells

Sarhan, D., Cichocki, F., Zhang, B., Yingst, A., Spellman, S. R., Cooley, S., Verneris, M. R., Blazar, B. R. & Miller, J. S., Oct 1 2016, In : Cancer Research. 76, 19, p. 5696-5706 11 p.

Research output: Contribution to journalArticle

Open Access
52 Scopus citations

A deletion/insertion polymorphism in the human BCR gene on chromosome 22

Rubin, C. M., Blazar, B. R., Hooberman, A. L., Dickler, M. N., Miller, B. A. & Westbrook, C. A., Sep 12 1988, In : Nucleic acids research. 16, 17, 1 p.

Research output: Contribution to journalArticle

5 Scopus citations

Adeno-associated virus-mediated delivery of a mutant endostatin in combination with carboplatin treatment inhibits orthotopic growth of ovarian cancer and improves long-term survival

Subramanian, I. V., Nguyen, T. M. B., Truskinovsky, A. M., Tolar, J., Blazar, B. R. & Ramakrishnan, S., Apr 15 2006, In : Cancer Research. 66, 8, p. 4319-4328 10 p.

Research output: Contribution to journalArticle

36 Scopus citations

Adenosine receptor A2a deficiency in leukocytes increases arterial neointima formation in apolipoprotein E-deficient mice

Wang, H., Zhang, W., Tang, R., Zhu, C., Bucher, C., Blazar, B. R., Geng, J. G., Zhang, C., Linden, J., Wu, C. & Huo, Y., May 1 2010, In : Arteriosclerosis, thrombosis, and vascular biology. 30, 5, p. 915-922 8 p.

Research output: Contribution to journalArticle

16 Scopus citations

Adiposity induces lethal cytokine storm after systemic administration of stimulatory immunotherapy regimens in aged mice

Mirsoian, A., Bouchlaka, M. N., Sckisel, G. D., Chen, M., Pai, C. C. S., Maverakis, E., Spencer, R. G., Fishbein, K. W., Siddiqui, S., Monjazeb, A. M., Martin, B., Maudsley, S., Hesdorffer, C., Ferrucci, L., Longo, D. L., Blazar, B. R., Wiltrout, R. H., Taub, D. D. & Murphy, W. J., Jan 1 2014, In : Journal of Experimental Medicine. 211, 12, p. 2373-2383 11 p.

Research output: Contribution to journalArticle

54 Scopus citations

Administration of either anti-CD40 or interleukin-12 following lethal total body irradiation induces acute lethal toxicity affecting the gut

Hixon, J. A., Anver, M. R., Blazar, B. R., Panoskaltsis-Mortari, A., Wiltrout, R. H. & Murphy, W. J., Jan 1 2002, In : Biology of Blood and Marrow Transplantation. 8, 6, p. 316-325 10 p.

Research output: Contribution to journalArticle

Open Access
17 Scopus citations
Open Access
49 Scopus citations

A Functional Bioluminescent Zebrafish Screen for Enhancing Hematopoietic Cell Homing

Astuti, Y., Kramer, A. C., Blake, A. L., Blazar, B. R., Tolar, J., Taisto, M. E. & Lund, T. C., Jan 10 2017, In : Stem Cell Reports. 8, 1, p. 177-190 14 p.

Research output: Contribution to journalArticle

Open Access
5 Scopus citations

Aging predisposes to acute inflammatory induced pathology after tumor immunotherapy

Bouchlaka, M. N., Sckisel, G. D., Chen, M., Mirsoian, A., Zamora, A. E., Maverakis, E., Wilkins, D. E. C., Alderson, K. L., Hsiao, H. H., Weiss, J. M., Monjazeb, A. M., Hesdorffer, C., Ferrucci, L., Longo, D. L., Blazar, B. R., Wiltrout, R. H., Redelman, D., Taub, D. D. & Murphy, W. J., Oct 1 2013, In : Journal of Experimental Medicine. 210, 11, p. 2223-2237 15 p.

Research output: Contribution to journalArticle

67 Scopus citations

Allogeneic bone marrow transplantation for x–linkd lymhoproliferative syndrome

Filipovich, A. H., Blazar, B. R., Ramsay, N. K. C., Kersey, J. H., Zelkowitz, L., Harada, S. & Purtilo, D. T., Aug 1986, In : Transplantation. 42, 2, p. 222-224 3 p.

Research output: Contribution to journalArticle

20 Scopus citations
49 Scopus citations

A low frequency of pancreatic islet insulin-expressing cells derived from cord blood stem cell allografts in humans

Huang, C. J., Butler, A. E., Moran, A., Rao, P. N., Wagner, J. E., Blazar, B. R., Rizza, R. A., Manivel, J. C. & Butler, P. C., May 1 2011, In : Diabetologia. 54, 5, p. 1066-1074 9 p.

Research output: Contribution to journalArticle

7 Scopus citations

Alpha phenyl-tert-butyl nitrone (PBN) protects syngeneic marrow transplant recipients from the lethal cytokine syndrome occurring after agonistic CD40 antibody administration

Gendelman, M., Halligan, N., Komorowski, R., Logan, B., Murphy, W. J., Blazar, B. R., Pritchard, K. A. & Drobyski, W. R., Jan 1 2005, In : Blood. 105, 1, p. 428-431 4 p.

Research output: Contribution to journalArticle

9 Scopus citations

Alteration of Tumor Metabolism by CD4+ T Cells Leads to TNF-α-Dependent Intensification of Oxidative Stress and Tumor Cell Death

Habtetsion, T., Ding, Z. C., Pi, W., Li, T., Lu, C., Chen, T., Xi, C., Spartz, H., Liu, K., Hao, Z., Mivechi, N., Huo, Y., Blazar, B. R., Munn, D. H. & Zhou, G., Aug 7 2018, In : Cell Metabolism. 28, 2, p. 228-242.e6

Research output: Contribution to journalArticle

Open Access
9 Scopus citations

Altered B-cell homeostasis and excess BAFF in human chronic graft-versus-host disease

Sarantopoulos, S., Stevenson, K. E., Kim, H. T., Cutler, C. S., Bhuiya, N. S., Schowalter, M., Ho, V. T., Alyea, E. P., Koreth, J., Blazar, B. R., Soiffer, R. J., Antin, J. H. & Ritz, J., Nov 17 2009, In : Blood. 113, 16, p. 3865-3874 10 p.

Research output: Contribution to journalArticle

200 Scopus citations

Altered T-cell receptor + CD28-mediated signaling and blocked cell cycle progression in interleukin 10 and transforming growth factor-β-treated alloreactive T cells that do not induce graft-versus-host disease

Boussiotis, V. A., Chen, Z. M., Zeller, J. C., Murphy, W. J., Berezovskaya, A., Narula, S., Roncarolo, M. G. & Blazar, B. R., Jan 15 2001, In : Blood. 97, 2, p. 565-571 7 p.

Research output: Contribution to journalArticle

42 Scopus citations
55 Scopus citations

Amelioration of epidermolysis bullosa by transfer of wild-type bone marrow cells

Tolar, J., Akemi, I. Y., Riddle, M., McElmurry, R. T., Osborn, M., Xia, L., Lund, T., Slattery, C., Uitto, J., Christiano, A. M., Wagner, J. E. & Blazar, B. R., Jan 29 2009, In : Blood. 113, 5, p. 1167-1174 8 p.

Research output: Contribution to journalArticle

122 Scopus citations
1 Scopus citations

Amphiregulin modifies the Minnesota acute graft-versus-host disease risk score: Results from BMT CTN 0302/0802

Holtan, S. G., DeFor, T. E., Panoskaltsis-Mortari, A., Khera, N., Levine, J. E., Flowers, M. E. D., Lee, S. J., Inamoto, Y., Chen, G. L., Mayer, S., Arora, M., Palmer, J., Cutler, C. S., Arai, S., Lazaryan, A., Newell, L. F., Jagasia, M. H., Pusic, I., Wood, W. A., Renteria, A. S. & 17 others, Yanik, G., Hogan, W. J., Hexner, E., Ayuk, F., Holler, E., Bunworasate, U., Efebera, Y. A., Ferrara, J. L. M., Pidala, J., Howard, A., Wu, J., Bolaños-Meade, J., Ho, V., Alousi, A., Blazar, B. R., Weisdorf, D. J. & MacMillan, M. L., Aug 14 2018, In : Blood Advances. 2, 15, p. 1882-1888 7 p.

Research output: Contribution to journalArticle

Open Access
5 Scopus citations
Open Access
32 Scopus citations

An aberrant NOTCH2-BCR signaling axis in B cells from patients with chronic GVHD

Poe, J. C., Jia, W., Su, H., Anand, S., Rose, J. J., Tata, P. V., Suthers, A. N., Jones, C. D., Kuan, P. F., Vincent, B. G., Serody, J. S., Horwitz, M. E., Ho, V. T., Pavletic, S. Z., Hakim, F. T., Owzar, K., Zhang, D., Blazar, B. R., Siebel, C. W., Chao, N. J. & 2 others, Maillard, I. & Sarantopoulos, S., Nov 9 2017, In : Blood. 130, 19, p. 2131-2145 15 p.

Research output: Contribution to journalArticle

Open Access
12 Scopus citations

An absence of CCR5 on donor cells results in acceleration of acute graft-vs-host disease

Welniak, L. A., Wang, Z., Sun, K., Kuziel, W., Anver, M. R., Blazar, B. R. & Murphy, W. J., Mar 1 2004, In : Experimental Hematology. 32, 3, p. 318-324 7 p.

Research output: Contribution to journalArticle

55 Scopus citations

An activated Th17-prone T cell subset involved in chronic graft-versus-host disease sensitive to pharmacological inhibition

Forcade, E., Paz, K., Flynn, R., Griesenauer, B., Amet, T., Li, W., Liu, L., Bakoyannis, G., Jiang, D., Chu, H. W., Lobera, M., Yang, J., Wilkes, D. S., Du, J., Gartlan, K., Hill, G. R., MacDonald, K. P., Espada, E. L., Blanco, P., Serody, J. S. & 7 others, Koreth, J., Cutler, C. S., Antin, J. H., Soiffer, R. J., Ritz, J., Paczesny, S. & Blazar, B. R., Jun 15 2017, In : JCI Insight. 2, 12

Research output: Contribution to journalArticle

Open Access
21 Scopus citations

An alpha-defensin gene single nucleotide polymorphism modulates the gut microbiota and may alter the risk of acute graft-versus-host disease

Rashidi, A., Herman, A., Gomes, A. L. C., Peled, J. U., Jenq, R. R., Brereton, D. G., Staley, C., Blazar, B. R. & Weisdorf, D. J., Jun 1 2020, In : British journal of haematology. 189, 5, p. 926-930 5 p.

Research output: Contribution to journalArticle

Analysis of BMT CTN-0201 and -0901 samples did not reproduce the reported association between recipient REG3A rs7588571 and chronic GVHD

Rashidi, A., Shanley, R., Anasetti, C., Waller, E. K., Scott, B. L., Blazar, B. R. & Weisdorf, D. J., Mar 1 2019, In : Bone marrow transplantation. 54, 3, p. 490-493 4 p.

Research output: Contribution to journalArticle