1982 …2020

Research output per year

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Research Output

β2-Adrenergic receptor activation on donor cells ameliorates acute GvHD

Mohammadpour, H., Sarow, J. L., MacDonald, C. R., Chen, G. L., Qiu, J., Sharma, U. C., Cao, X., Herr, M. M., Hahn, T. E., Blazar, B. R., Repasky, E. A. & McCarthy, P. L., Jun 18 2020, In : JCI Insight. 5, 12

Research output: Contribution to journalArticle

Open Access

Zinc fingers hit off target.

Cheng, L., Blazar, B., High, K. & Porteus, M., Oct 1 2011, In : Nature Medicine. 17, 10, p. 1192-1193 2 p.

Research output: Contribution to journalArticle

5 Scopus citations

Zebrafish stromal cells have endothelial properties and support hematopoietic cells

Lund, T. C., Glass, T. J., Somani, A., Nair, S., Tolar, J., Nyquist, M., Patrinostro, X. & Blazar, B. R., Jan 2012, In : Experimental Hematology. 40, 1, p. 61-70.e1

Research output: Contribution to journalArticle

4 Scopus citations

Vstm3 is a member of the CD28 family and an important modulator of T-cell function

Levin, S. D., Taft, D. W., Brandt, C. S., Bucher, C., Howard, E. D., Chadwick, E. M., Johnston, J., Hammond, A., Bontadelli, K., Ardourel, D., Hebb, L., Wolf, A., Bukowski, T. R., Rixon, M. W., Kuijper, J. L., Ostrander, C. D., West, J. W., Bilsborough, J., Fox, B., Gao, Z. & 4 others, Xu, W., Ramsdell, F., Blazar, B. R. & Lewis, K. E., Apr 1 2011, In : European Journal of Immunology. 41, 4, p. 902-915 14 p.

Research output: Contribution to journalArticle

133 Scopus citations

VISTA is a checkpoint regulator for naïve T cell quiescence and peripheral tolerance

ElTanbouly, M. A., Zhao, Y., Nowak, E., Li, J., Schaafsma, E., Le Mercier, I., Ceeraz, S., Lines, J. L., Peng, C., Carriere, C., Huang, X., Day, M., Koehn, B., Lee, S. W., Morales, M. S., Hogquist, K. A., Jameson, S. C., Mueller, D., Rothstein, J., Blazar, B. R. & 2 others, Cheng, C. & Noelle, R. J., Jan 17 2020, In : Science. 367, 6475, eaay0524.

Research output: Contribution to journalArticle

6 Scopus citations

Virus-specific memory T cells populate tumors and can be repurposed for tumor immunotherapy

Rosato, P. C., Wijeyesinghe, S., Stolley, J. M., Nelson, C. E., Davis, R. L., Manlove, L. S., Pennell, C. A., Blazar, B. R., Chen, C. C., Geller, M. A., Vezys, V. & Masopust, D., Dec 1 2019, In : Nature communications. 10, 1, 567.

Research output: Contribution to journalArticle

Open Access
23 Scopus citations

Validation of Minnesota acute graft-versus-host disease Risk Score

MacMillan, M. L., DeFor, T. E., Holtan, S. G., Rashidi, A., Blazar, B. R. & Weisdorf, D. J., Jan 31 2020, In : Haematologica. 105, 2, p. 519-524 6 p.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations
24 Scopus citations

Use of an anti-pan T-lymphocyte ricin A chain immunotoxin in steroid-resistant acute graft-versus-host disease

Byers, V. S., Henslee, P. J., Kernan, N. A., Blazar, B. R., Gingrich, R., Phillips, G. L., LeMaistre, C. F., Gilliland, G., Antin, J. H., Martin, P., Tutscha, P. J., Trown, P., Ackerman, S. K., O'Reilly, R. J. & Scannon, P. J., 1990, In : Blood. 75, 7, p. 1426-1432 7 p.

Research output: Contribution to journalArticle

95 Scopus citations

Unrelated donor bone marrow transplantation therapy for chronic myelogenous leukemia

McGlave, P., Scott, E., Ramsay, N., Arthur, D., Blazar, B., McCullough, J. & Kersey, J., 1987, In : Blood. 70, 3, p. 877-881 5 p.

Research output: Contribution to journalArticle

Open Access
45 Scopus citations

Unrelated donor bone marrow transplantation for correction of lethal congenital immunodeficiencies

Filipovich, A. H., Shapiro, R. S., Ramsay, N. K. C., Kim, T., Blazar, B., Kersey, J. & McGlave, P., 1992, In : Blood. 80, 1, p. 270-276 7 p.

Research output: Contribution to journalArticle

Open Access
75 Scopus citations

Unrelated donor bone marrow transplantation for children with acute leukemia

Davies, S. M., Wagner, J. E., Shu, X. O., Blazar, B. R., Katsanis, E., Orchard, P. J., Kersey, J. H., Dusenbery, K. E., Weisdorf, D. J., Mc Glave, P. B. & Ramsay, N. K., Feb 1997, In : Journal of Clinical Oncology. 15, 2, p. 557-565 9 p.

Research output: Contribution to journalArticle

93 Scopus citations

Unrelated donor bone marrow transplantation for children and adolescents with aplastic anaemia or myelodysplasia

Davies, S. M., Wagner, J. E., Defor, T., Blazar, B. R., Katsanis, E., Kersey, J. H., Orchard, P. J., Mcglave, P. B., Weisdorf, D. J. & Ramsay, N. K. C., Jan 1 1997, In : British Journal of Haematology. 96, 4, p. 749-756 8 p.

Research output: Contribution to journalArticle

71 Scopus citations

Unrelated donor bone marrow transplantation: Influence of HLA A and B incompatibility on outcome

Davies, S. M., Shu, X. O., Blazar, B. R., Filipovich, A. M., Kersey, J. H., Krivit, W., McCullough, J., Miller, W. J., Ramsay, N. K. C., Segall, M., Wagner, J. E., Weisdorf, D. J. & McGlave, P. B., Aug 15 1995, In : Blood. 86, 4, p. 1636-1642 7 p.

Research output: Contribution to journalArticle

Open Access
119 Scopus citations

Unrelated dnor bone marrow transplantation for hematological malignancies-current status

Davies, S. M., Wagner, J. E., Weisdorf, D. J., Shu, X. O., Blazar, B. R., Enright, H., McGlave, P. B. & Ramsay, N. K. C., Jan 1 1996, In : Leukemia and Lymphoma. 23, 3-4, p. 221-226 6 p.

Research output: Contribution to journalArticle

23 Scopus citations

Understanding Luminal Microorganisms and Their Potential Effectiveness in Treating Intestinal Inflammation

Ince, M. N., Blazar, B. R., Edmond, M. B., Tricot, G. & Wannemuehler, M. J., Jan 1 2016, In : Inflammatory bowel diseases. 22, 1, p. 194-201 8 p.

Research output: Contribution to journalReview article

Open Access
7 Scopus citations

Understanding Chronic GVHD from Different Angles

Blazar, B., White, E. S. & Couriel, D., Jan 1 2012, In : Biology of Blood and Marrow Transplantation. 18, 1 SUPPL., p. S184-S188

Research output: Contribution to journalArticle

8 Scopus citations
415 Scopus citations
32 Scopus citations

Umbilical cord blood regulatory T-cell expansion and functional effects of tumor necrosis factor receptor family members OX40 and 4-1BB expressed on artificial antigen-presenting cells

Hippen, K. L., Harker-Murray, P., Porter, S. B., Merkel, S. C., Londer, A., Taylor, D. K., Bina, M., Panoskaltsis-Mortari, A., Rubinstein, P., Van Rooijen, N., Golovina, T. N., Suhoski, M. M., Miller, J. S., Wagner, J. E., June, C. H., Riley, J. L. & Blazar, B. R., Oct 1 2008, In : Blood. 112, 7, p. 2847-2857 11 p.

Research output: Contribution to journalArticle

109 Scopus citations

Umbilical cord blood-derived T regulatory cells to prevent GVHD: Kinetics, toxicity profile, and clinical effect

Brunstein, C. G., Miller, J. S., McKenna, D. H., Hippen, K. L., DeFor, T. E., Sumstad, D., Curtsinger, J., Verneris, M. R., MacMillan, M. L., Levine, B. L., Riley, J. L., June, C. H., Le, C., Weisdorf, D. J., McGlave, P. B., Blazar, B. R. & Wagner, J. E., Feb 25 2016, In : Blood. 127, 8, p. 1044-1051 8 p.

Research output: Contribution to journalArticle

Open Access
161 Scopus citations

Type 2 innate lymphoid cells treat and prevent acute gastrointestinal graft-versus-host disease

Bruce, D. W., Stefanski, H. E., Vincent, B. G., Dant, T. A., Reisdorf, S., Bommiasamy, H., Serody, D. A., Wilson, J. E., McKinnon, K. P., Shlomchik, W. D., Armistead, P. M., Ting, J. P. Y., Woosley, J. T., Blazar, B. R., Zaiss, D. M. W., McKenzie, A. N. J., Coghill, J. M. & Serody, J. S., May 1 2017, In : Journal of Clinical Investigation. 127, 5, p. 1813-1825 13 p.

Research output: Contribution to journalArticle

Open Access
30 Scopus citations

Tumor regression by anti-CD40 and interleukin-2: Role of CD40 in hematopoietic cells and organ-specific effects

Welniak, L. A., Shorts, L., Subleski, J., Blazar, B. R., Wiltrout, R. H. & Murphy, W. J., Aug 1 2004, In : Biology of Blood and Marrow Transplantation. 10, 8, p. 534-539 6 p.

Research output: Contribution to journalArticle

6 Scopus citations

Tumor-induced mechanical hyperalgesia involves CGRP receptors and altered innervation and vascularization of DsRed2 fluorescent hindpaw tumors

Wacnik, P. W., Baker, C. M., Herron, M. J., Kren, B. T., Blazar, B. R., Wilcox, G. L., Hordinsky, M. K., Beitz, A. J. & Ericson, M. E., May 2005, In : Pain. 115, 1-2, p. 95-106 12 p.

Research output: Contribution to journalArticle

38 Scopus citations

Tumor growth control with IDO-silencing Salmonellareply

Manuel, E. R., Blazar, B. R. & Diamond, D. J., Jul 15 2013, In : Cancer Research. 73, 14, p. 4592-4593 2 p.

Research output: Contribution to journalLetter

2 Scopus citations

Treg engage lymphotoxin beta receptor for afferent lymphatic transendothelial migration

Brinkman, C. C., Iwami, D., Hritzo, M. K., Xiong, Y., Ahmad, S., Simon, T., Hippen, K. L., Blazar, B. R. & Bromberg, J. S., Jun 21 2016, In : Nature communications. 7, 12021.

Research output: Contribution to journalArticle

Open Access
21 Scopus citations

Treatment of steroid-refractory acute graft-versus-host disease with anti-CD147 monoclonal antibody ABX-CBL

Joachim Deeg, H., Blazar, B. R., Bolwell, B. J., Long, G. D., Schuening, F., Cunningham, J., Rifkin, R. M., Abhyankar, S., Briggs, A. D., Burt, R., Lipani, J., Roskos, L. K., Michael White, J., Havrilla, N., Schwab, G. & Heslop, H. E., Oct 1 2001, In : Blood. 98, 7, p. 2052-2058 7 p.

Research output: Contribution to journalArticle

87 Scopus citations

Treatment of moderate and severe acute GVHD after allogeneic bone marrow transplantation

Hings, I. M., Severson, R., Filipovich, A. H., Blazar, B. R., Kersey, J. H., Ramsay, N. K. C., Mc Glave, P. B. & Weisdorf, D. J., Aug 27 1994, In : Transplantation. 58, 4, p. 337-442 106 p.

Research output: Contribution to journalArticle

56 Scopus citations

Treatment of moderate/severe acute graft-versus-host disease after allogeneic bone marrow transplantation: An analysis of clinical risk features and outcome

Weisdorf, D., Haake, R., Blazar, B., Miller, W., McGlave, P., Ramsay, N., Kersey, J. & Filipovich, A., 1990, In : Blood. 75, 4, p. 1024-1030 7 p.

Research output: Contribution to journalArticle

Open Access
297 Scopus citations

Treatment of chronic graft-versus-host disease with bortezomib

Pai, C. C. S., Chen, M., Mirsoian, A., Grossenbacher, S. K., Tellez, J., Ames, E., Sun, K., Jagdeo, J., Blazar, B. R., Murphy, W. J. & Abedi, M., Jan 1 2014, In : Blood. 124, 10, p. 1677-1688 12 p.

Research output: Contribution to journalArticle

43 Scopus citations

Trans-presentation of donor-derived interleukin 15 is necessary for the rapid onset of acute graft-versus-host disease but not for graft-versus-tumor activity

Blaser, B. W., Schwind, N. R., Karol, S., Chang, D., Shin, S., Roychowdhury, S., Becknell, B., Ferketich, A. K., Kusewitt, D. F., Blazar, B. R. & Caligiuri, M. A., Oct 1 2006, In : Blood. 108, 7, p. 2463-2469 7 p.

Research output: Contribution to journalArticle

23 Scopus citations

Transplantation of unrelated donor umbilical cord blood in 102 patients with malignant and nonmalignant diseases: Influence of CD34 cell dose and HLA disparity on treatment-related mortality and survival

Wagner, J. E., Barker, J. N., De For, T. E., Scott Baker, K., Blazar, B. R., Eide, C., Goldman, A., Kersey, J., Krivit, W., MacMillan, M. L., Orchard, P. J., Peters, C., Weisdorf, D. J., Ramsay, N. K. C. & Davies, S. M., Sep 1 2002, In : Blood. 100, 5, p. 1611-1618 8 p.

Research output: Contribution to journalArticle

834 Scopus citations
172 Scopus citations

Transplantation of 2 partially HLA-matched umbilical cord blood units to enhance engraftment in adults with hematologic malignancy

Barker, J. N., Weisdorf, D. J., DeFor, T. E., Blazar, B. R., McGlave, P. B., Miller, J. S., Verfaillie, C. M. & Wagner, J. E., Feb 1 2005, In : Blood. 105, 3, p. 1343-1347 5 p.

Research output: Contribution to journalArticle

693 Scopus citations

Transient blockade of the inducible costimulator pathway generates long-term tolerance to factor VIII after nonviral gene transfer into hemophilia A mice

Peng, B., Ye, P., Blazar, B. R., Freeman, G. J., Rawlings, D. J., Ochs, H. D. & Miao, C. H., Sep 1 2008, In : Blood. 112, 5, p. 1662-1672 11 p.

Research output: Contribution to journalArticle

46 Scopus citations
27 Scopus citations

Transgene expression and silencing in a tick cell line: A model system for functional tick genomics

Kurtti, T. J., Mattila, J. T., Herron, M. J., Felsheim, R. F., Baldridge, G. D., Burkhardt, N. Y., Blazar, B. R., Hackett, P. B., Meyer, J. M. & Munderloh, U. G., Oct 1 2008, In : Insect Biochemistry and Molecular Biology. 38, 10, p. 963-968 6 p.

Research output: Contribution to journalArticle

17 Scopus citations
18 Scopus citations

Transcriptome analysis of GVHD reveals aurora kinase a as a targetable pathway for disease prevention

Furlan, S. N., Watkins, B., Tkachev, V., Flynn, R., Cooley, S., Ramakrishnan, S., Singh, K., Giver, C., Hamby, K., Stempora, L., Garrett, A., Chen, J., Betz, K. M., Ziegler, C. G. K., Tharp, G. K., Bosinger, S. E., Promislow, D. E. L., Miller, J. S., Waller, E. K., Blazar, B. R. & 1 others, Kean, L. S., Nov 25 2015, In : Science Translational Medicine. 7, 315, 3231.

Research output: Contribution to journalArticle

27 Scopus citations

TRAF6 directs FOXP3 localization and facilitates regulatory T-cell function through K63-linked ubiquitination

Ni, X., Kou, W., Gu, J., Wei, P., Wu, X., Peng, H., Tao, J., Yan, W., Yang, X., Lebid, A., Park, B. V., Chen, Z., Tian, Y., Fu, J., Newman, S., Wang, X., Shen, H., Li, B., Blazar, B. R., Wang, X. & 3 others, Barbi, J., Pan, F. & Lu, L., May 2 2019, In : EMBO Journal. 38, 9, e99766.

Research output: Contribution to journalArticle

Open Access
14 Scopus citations
19 Scopus citations

Toll-like receptor 9 signaling by CpG-B oligodeoxynucleotides induces an apoptotic pathway in human chronic lymphocytic leukemia B cells

Liang, X., Moseman, E. A., Farrar, M. A., Bachanova, V., Weisdorf, D. J., Blazar, B. R. & Chen, W., Jun 17 2010, In : Blood. 115, 24, p. 5041-5052 12 p.

Research output: Contribution to journalArticle

78 Scopus citations

Tolerance induction of alloreactive T cells via ex vivo blockade of the CD40:CD40L costimulatory pathway results in the generation of a potent immune regulatory cell

Taylor, P. A., Friedman, T. M., Korngold, R., Noelle, R. J. & Blazar, B. R., Jun 15 2002, In : Blood. 99, 12, p. 4601-4609 9 p.

Research output: Contribution to journalArticle

118 Scopus citations

Tolerance induction by third-party "off-the-shelf" CD4 +CD25+ Treg cells

Steiner, D., Brunicki, N., Blazar, B. R., Bachar-Lustig, E. & Reisner, Y., Jan 1 2006, In : Experimental Hematology. 34, 1, p. 66-71 6 p.

Research output: Contribution to journalArticle

38 Scopus citations

T-lymphocyte production of macrophage inflammatory protein-1α is critical to the recruitment of CD8+ T cells to the liver, lung, and spleen during graft-versus-host disease

Serody, J. S., Burkett, S. E., Panoskaltsis-Mortari, A., Ng-Cashin, J., McMahon, E., Matsushima, G. K., Lira, S. A., Cook, D. N. & Blazar, B. R., Nov 1 2000, In : Blood. 96, 9, p. 2973-2980 8 p.

Research output: Contribution to journalArticle

111 Scopus citations

TLR agonists regulate alloresponses and uncover a critical role for donor APCs in allogeneic bone marrow rejection

Taylor, P. A., Ehrhardt, M. J., Lees, C. J., Panoskaltsis-Mortari, A., Krieg, A. M., Sharpe, A. H., Murphy, W. J., Serody, J. S., Hemmi, H., Akira, S., Levy, R. B. & Blazar, B. R., Oct 15 2008, In : Blood. 112, 8, p. 3508-3516 9 p.

Research output: Contribution to journalArticle

56 Scopus citations

Tissue mast cell counts may be associated with decreased severity of gastrointestinal acute GVHD and nonrelapse mortality

Ustun, C., DeFor, T. E., Karadag, F. K., Yun, H. D., Nathan, S., Brunstein, C. G., Blazar, B. R., Weisdorf, D. J., Holtan, S. G. & Amin, K., May 26 2020, In : Blood Advances. 4, 10, p. 2317-2324 8 p.

Research output: Contribution to journalArticle

Open Access

Tim-3 is an inducible human natural killer cell receptor that enhances interferon gamma production in response to galectin-9

Gleason, M. K., Lenvik, T. R., McCullar, V., Felices, M., O'Brien, M. S., Cooley, S. A., Verneris, M. R., Cichocki, F., Holman, C. J., Panoskaltsis-Mortari, A., Niki, T., Hirashima, M., Blazar, B. R. & Miller, J. S., Mar 29 2012, In : Blood. 119, 13, p. 3064-3072 9 p.

Research output: Contribution to journalArticle

163 Scopus citations

Thymic T-cell development in allogeneic stem cell transplantation

Krenger, W., Blazar, B. R. & Holländer, G. A., Jun 23 2011, In : Blood. 117, 25, p. 6768-6776 9 p.

Research output: Contribution to journalReview article

106 Scopus citations