1982 …2020

Research output per year

If you made any changes in Pure these will be visible here soon.

Research Output

IFN-γ receptor-deficient donor T cells mediate protection from graft-versus-host disease and preserve graft-versus-tumor responses after allogeneic bone marrow transplantation

Sun, K., Hsiao, H. H., Li, M., Ames, E., Bouchlaka, M., Welniak, L. A., Hagino, T., Jagdeo, J., Pai, C. C., Chen, M., Blazar, B. R., Abedi, M. & Murphy, W. J., Aug 15 2012, In : Journal of Immunology. 189, 4, p. 2033-2042 10 p.

Research output: Contribution to journalArticle

9 Scopus citations

IL-10 and TGF-β induce alloreactive CD4+CD25- T cells to acquire regulatory cell function

Chen, Z. M., O'Shaughnessy, M. J., Gramaglia, I., Panoskaltsis-Mortari, A., Murphy, W. J., Narula, S., Roncarolo, M. G. & Blazar, B. R., Jun 15 2003, In : Blood. 101, 12, p. 5076-5083 8 p.

Research output: Contribution to journalArticle

151 Scopus citations

IL-15 administration following syngeneic bone marrow transplantation prolongs survival of lymphoma bearing mice

Katsanis, E., Xu, Z., Panoskaltsis-Mortari, A., Weisdorf, D. J., Widmer, M. B. & Blazar, B. R., Sep 27 1996, In : Transplantation. 62, 6, p. 872-875 4 p.

Research output: Contribution to journalArticle

27 Scopus citations
Open Access
95 Scopus citations

IL-21 blockade reduces graft-versus-host disease mortality by supporting inducible T regulatory cell generation

Bucher, C., Koch, L., Vogtenhuber, C., Goren, E., Munger, M., Panoskaltsis-Mortari, A., Sivakumar, P. & Blazar, B. R., Dec 17 2009, In : Blood. 114, 26, p. 5375-5384 10 p.

Research output: Contribution to journalArticle

102 Scopus citations

IL-2-based immunotherapy after authologous transplantation for lymphoma and breast cancer induces immune activation and cytokine release: A phase I/II trial

Burns, L. J., Weisdorf, D. J., DeFor, T. E., Vesole, D. H., Repka, T. L., Blazar, B. R., Burger, S. R., Panoskaltsis-Mortari, A., Keever-Taylor, C. A., Zhang, M. J. & Miller, J. S., Jul 1 2003, In : Bone marrow transplantation. 32, 2, p. 177-186 10 p.

Research output: Contribution to journalArticle

150 Scopus citations

IL-2 enhances ex vivo-expanded regulatory T-cell persistence after adoptive transfer

Furlan, S. N., Singh, K., Lopez, C., Tkachev, V., Hunt, D. J., Hibbard, J., Betz, K. M., Blazar, B. R., Trapnell, C. & Kean, L. S., Apr 28 2020, In : Blood Advances. 4, 8, p. 1594-1605 12 p.

Research output: Contribution to journalArticle

Open Access

IL-2 receptor β-dependent STAT5 activation is required for the development of Foxp3+ regulatory T cells

Burchill, M. A., Yang, J., Vogtenhuber, C., Blazar, B. R. & Farrar, M. A., Jan 1 2007, In : Journal of Immunology. 178, 1, p. 280-290 11 p.

Research output: Contribution to journalArticle

Open Access
519 Scopus citations

IL-33 is an unconventional alarmin that stimulates IL-2 secretion by dendritic cells to selectively expand IL-33R/ST2+ regulatory T cells

Matta, B. M., Lott, J. M., Mathews, L. R., Liu, Q., Rosborough, B. R., Blazar, B. R. & Turnquist, H. R., Oct 15 2014, In : Journal of Immunology. 193, 8, p. 4010-4020 11 p.

Research output: Contribution to journalArticle

109 Scopus citations

IL-7 signaling imparts polyfunctionality and stemness potential to CD4+ T cells

Ding, Z. C., Liu, C., Cao, Y., Habtetsion, T., Kuczma, M., Pi, W., Kong, H., Cacan, E., Greer, S. F., Cui, Y., Blazar, B. R., Munn, D. H. & Zhou, G., Jun 2 2016, In : OncoImmunology. 5, 6, e1171445.

Research output: Contribution to journalArticle

Open Access
7 Scopus citations

Immune Biology of Allogeneic Hematopoietic Stem Cell Transplantation

Socie, G. & Blazar, B. R., Jan 1 2013, Elsevier Inc.

Research output: Book/ReportBook

1 Scopus citations

Immune Regulatory Cell Biology and Clinical Applications to Prevent or Treat Acute Graft-Versus-Host Disease

Blazar, B. R., Feb 2019, In : Engineering. 5, 1, p. 98-105 8 p.

Research output: Contribution to journalReview article

Open Access

Immune regulatory cell infusion for graft-versus-host disease prevention and therapy

Blazar, B. R., MacDonald, K. P. A. & Hill, G. R., Jun 14 2018, In : Blood. 131, 24, p. 2651-2660 10 p.

Research output: Contribution to journalReview article

Open Access
37 Scopus citations
36 Scopus citations

Immunobiology of allogeneic hematopoietic stem cell transplantation

Welniak, L. A., Blazar, B. R. & Murphy, W. J., 2007, In : Annual Review of Immunology. 25, p. 139-170 32 p.

Research output: Contribution to journalArticle

337 Scopus citations

Immunosuppressive myeloid cells induced by chemotherapy attenuate antitumor cd4 t-cell responses through the PD-1-PD-L1 axis

Ding, Z. C., Lu, X., Yu, M., Lemos, H., Huang, L., Chandler, P., Liu, K., Walters, M., Krasinski, A., Mack, M., Blazar, B. R., Mellor, A. L., Munn, D. H. & Zhou, G., Jul 1 2014, In : Cancer Research. 74, 13, p. 3441-3453 13 p.

Research output: Contribution to journalArticle

68 Scopus citations
12 Scopus citations
Open Access
21 Scopus citations

Impaired bone marrow B-cell development in mice with a bronchiolitis obliterans model of cGVHD

Kolupaev, O. V., Dant, T. A., Bommiasamy, H., Bruce, D. W., Fowler, K. A., Tilley, S. L., McKinnon, K. P., Sarantopoulos, S., Blazar, B. R., Coghill, J. M. & Serody, J. S., Sep 25 2018, In : Blood Advances. 2, 18, p. 2307-2319 13 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Importance in timing of cyclophosphamide on the enhancement of interleukin-2-induced cytolysis

Katsanis, E., Bausero, M. A., Ochoa, A. C., Loeffler, C. M., Blazar, B. R., Leonard, A. S. & Anderson, P. M., Mar 1 1991, In : Cancer Immunology Immunotherapy. 34, 2, p. 74-78 5 p.

Research output: Contribution to journalArticle

12 Scopus citations

Improved graft-versus-host disease-free, relapse-free survival associated with bone marrow as the stem cell source in adults

Mehta, R. S., de Latour, R. P., DeFor, T. E., Robin, M., Lazaryan, A., Xhaard, A., Bejanyan, N., de Fontbrune, F. S., Arora, M., Brunstein, C. G., Blazar, B. R., Weisdorf, D. J., MacMillan, M. L., Socie, G. & Holtan, S. G., May 31 2016, In : Haematologica. 101, 6, p. 764-772 9 p.

Research output: Contribution to journalArticle

Open Access
15 Scopus citations
Open Access
12 Scopus citations

Inactivation of the adenosine A2A receptor protects apolipoprotein E-deficient mice from atherosclerosis

Wang, H., Zhang, W., Zhu, C., Bucher, C., Blazar, B. R., Zhang, C., Chen, J. F., Linden, J., Wu, C. & Huo, Y., Jul 1 2009, In : Arteriosclerosis, thrombosis, and vascular biology. 29, 7, p. 1046-1052 7 p.

Research output: Contribution to journalArticle

49 Scopus citations

Increased effector memory insulin-specific CD4+ T cells correlate with insulin autoantibodies in patients with recent-onset type 1 diabetes

Spanier, J. A., Sahli, N. L., Wilson, J. C., Martinov, T., T, D., Burrack, A. L., Finger, E. B., Blazar, B. R., Michels, A. W., Moran, A., Jenkins, M. & Fife, B. T., Dec 1 2017, In : Diabetes. 66, 12, p. 3051-3060 10 p.

Research output: Contribution to journalArticle

Open Access
18 Scopus citations

Increased mitochondrial apoptotic priming of human regulatory T cells after allogeneic hematopoietic stem cell transplantation

Murase, K., Kim, H. T., Gregory Bascug, O. R., Kawano, Y., Ryan, J., Matsuoka, K. I., Davids, M. S., Koreth, J., Ho, V. T., Cutler, C., Armand, P., Alyea, E. P., Blazar, B. R., Antin, J. H., Soiffer, R. J., Letai, A. & Ritz, J., Sep 1 2014, In : Haematologica. 99, 9, p. 1499-1508 10 p.

Research output: Contribution to journalArticle

10 Scopus citations

Increased T follicular helper cells and germinal center B cells are required for cGVHD and bronchiolitis obliterans

Flynn, R., Du, J., Veenstra, R. G., Reichenbach, D. K., Panoskaltsis-Mortari, A., Taylor, P. A., Freeman, G. J., Serody, J. S., Murphy, W. J., Munn, D. H., Sarantopoulos, S., Luznik, L., Maillard, I., Koreth, J., Cutler, C., Soiffer, R. J., Antin, J. H., Ritz, J., Dubovsky, J. A., Byrd, J. C. & 3 others, MacDonald, K. P., Hill, G. R. & Blazar, B. R., Jun 19 2014, In : Blood. 123, 25, p. 3988-3998 11 p.

Research output: Contribution to journalArticle

100 Scopus citations

Increasing Regulatory T Cells With Interleukin-2 and Interleukin-2 Antibody Complexes Attenuates Lung Inflammation and Heart Failure Progression

Wang, H., Hou, L., Kwak, D., Fassett, J., Xu, X., Chen, A., Chen, W., Blazar, B. R., Xu, Y., Hall, J. L., Ge, J. B., Bache, R. J. & Chen, Y., Jul 1 2016, In : Hypertension. 68, 1, p. 114-122 9 p.

Research output: Contribution to journalArticle

Open Access
30 Scopus citations

Indoleamine 2,3-dioxygenase is a critical regulator of acute graft-versus-host disease lethality

Jasperson, L. K., Bucher, C., Panoskaltsis-Mortari, A., Taylor, P. A., Mellor, A. L., Munn, D. H. & Blazar, B. R., Mar 15 2008, In : Blood. 111, 6, p. 3257-3265 9 p.

Research output: Contribution to journalArticle

111 Scopus citations
112 Scopus citations

Inducible T-cell receptor expression in precursor T cells for leukemia control

Hoseini, S. S., Hapke, M., Herbst, J., Wedekind, D., Baumann, R., Heinz, N., Schiedlmeier, B., Vignali, D. A. A., Van Den Brink, M. R. M., Schambach, A., Blazar, B. R. & Sauer, M. G., Jul 13 2015, In : Leukemia. 29, 7, p. 1530-1542 13 p.

Research output: Contribution to journalArticle

6 Scopus citations

Inducing the tryptophan catabolic pathway, indoleamine 2,3-dioxygenase (IDO), for suppression of graft-versus-host disease (GVHD) lethality

Koch, L. K., Bucher, C., Panoskaltsis-Mortari, A., Mellor, A. L., Munn, D. H. & Blazar, B. R., Dec 3 2009, In : Blood. 114, 24, p. 5062-5070 9 p.

Research output: Contribution to journalArticle

98 Scopus citations

Induction of CD4+ T cell alloantigen-specific hyporesponsiveness by IL- 10 and TGF-β

Zeller, J. C., Panoskaltsis-Mortari, A., Murphy, W. J., Ruscetti, F. W., Narula, S., Roncarolo, M. G. & Blazar, B. R., Oct 1 1999, In : Journal of Immunology. 163, 7, p. 3684-3691 8 p.

Research output: Contribution to journalArticle

175 Scopus citations

Induction of immunosuppressive functions and NF-κB by FLIP in monocytes

Fiore, A., Ugel, S., De Sanctis, F., Sandri, S., Fracasso, G., Trovato, R., Sartoris, S., Solito, S., Mandruzzato, S., Vascotto, F., Hippen, K. L., Mondanelli, G., Grohmann, U., Piro, G., Carbone, C., Melisi, D., Lawlor, R. T., Scarpa, A., Lamolinara, A., Iezzi, M. & 6 others, Fassan, M., Bicciato, S., Blazar, B. R., Sahin, U., Murray, P. J. & Bronte, V., Dec 1 2018, In : Nature communications. 9, 1, 5193.

Research output: Contribution to journalArticle

Open Access
10 Scopus citations

Induction of monocyte- and T-cell-attracting chemokines in the lung during the generation of idiopathic pneumonia syndrome following allogeneic murine bone marrow transplantation

Panoskaltsis-Mortari, A., Strieter, R. M., Hermanson, J. R., Fegeding, K. V., Murphy, W. J., Farrell, C. L., Lacey, D. L. & Blazar, B. R., Aug 1 2000, In : Blood. 96, 3, p. 834-839 6 p.

Research output: Contribution to journalArticle

53 Scopus citations

Induction of transplantation tolerance by combining non-myeloablative conditioning with delivery of alloantigen by T cells

Tian, C., Yuan, X., Bagley, J., Blazar, B. R., Sayegh, M. H. & Iacomini, J., May 1 2008, In : Clinical Immunology. 127, 2, p. 130-137 8 p.

Research output: Contribution to journalArticle

8 Scopus citations

Inflammasome effects in GvHD

Koehn, B., Zeiser, R. & Blazar, B. R., 2015, In : Oncotarget. 6, 36, p. 38444-38445 2 p.

Research output: Contribution to journalEditorial

4 Scopus citations

Inflammatory cytokines and the development of pulmonary complications after allogeneic hematopoietic cell transplantation in patients with inherited metabolic storage disorders

Kharbanda, S., Panoskaltsis-Mortari, A., Haddad, I. Y., Blazar, B. R., Orchard, P. J., Cornfield, D. N., Grewal, S. S., Peters, C., Regelmann, W. E., Milla, C. E. & Baker, K. S., Apr 1 2006, In : Biology of Blood and Marrow Transplantation. 12, 4, p. 430-437 8 p.

Research output: Contribution to journalArticle

19 Scopus citations

Influence of mouse colony environment on ability of perforin -/- (PKO) mice to reject TAP-1-/- marrow grafts

Austin, M. D., Kumar, V., Bennett, M., Levy, R. B. & Blazar, B. R., Mar 20 1998, In : FASEB Journal. 12, 5, p. A903

Research output: Contribution to journalArticle

Influenza infection results in local expansion of memory CD8+ T cells with antigen non-specific phenotype and function

Sckisel, G. D., Tietze, J. K., Zamora, A. E., Hsiao, H. H., Priest, S. O., Wilkins, D. E. C., Lanier, L. L., Blazar, B. R., Baumgarth, N. & Murphy, W. J., Jan 1 2014, In : Clinical and Experimental Immunology. 175, 1, p. 79-91 13 p.

Research output: Contribution to journalArticle

17 Scopus citations
81 Scopus citations

Infusion of ex vivo expanded T regulatory cells in adults transplanted with umbilical cord blood: Safety profile and detection kinetics

Brunstein, C. G., Miller, J. S., Cao, Q., McKenna, D. H., Hippen, K. L., Curtsinger, J., DeFor, T., Levine, B. L., June, C. H., Rubinstein, P., McGlave, P. B., Blazar, B. R. & Wagner, J. E., Jan 20 2011, In : Blood. 117, 3, p. 1061-1070 10 p.

Research output: Contribution to journalArticle

664 Scopus citations
9 Scopus citations

Inhibiting retinoic acid signaling ameliorates graft-versus-host disease by modifying T-cell differentiation and intestinal migration

Aoyama, K., Saha, A., Tolar, J., Riddle, M. J., Veenstra, R. G., Taylor, P. A., Blomhoff, R., Panoskaltsis-Mortari, A., Klebanoff, C. A., Socié, G., Munn, D. H., Murphy, W. J., Serody, J. S., Fulton, L. M., Teshima, T., Chandraratna, R. A., Dmitrovsky, E., Guo, Y., Noelle, R. J. & Blazar, B. R., 2013, In : Blood. 122, 12, p. 2125-2134 10 p.

Research output: Contribution to journalArticle

24 Scopus citations

Inhibition of acute graft-versus-host disease with retention of graft-versus-tumor effects by the proteasome inhibitior bortezomib

Sun, K., Welniak, L. A., Panoskaltsis-Mortari, A., O'Shaughnessy, M. J., Liu, H., Barao, I., Riordan, W., Sitcheran, R., Wysocki, C., Serody, J. S., Blazar, B. R., Sayers, T. J. & Murphy, W. J., May 21 2004, In : Proceedings of the National Academy of Sciences of the United States of America. 101, 21, p. 8120-8125 6 p.

Research output: Contribution to journalArticle

218 Scopus citations

Inhibition of Human Dendritic Cell ER Stress Response Reduces T Cell Alloreactivity Yet Spares Donor Anti-tumor Immunity

Betts, B. C., Locke, F. L., Sagatys, E. M., Pidala, J., Walton, K., Menges, M., Reff, J., Saha, A., Djeu, J. Y., Kiluk, J. V., Lee, M. C., Kim, J., Kang, C. W., Tang, C. H., Frieling, J., Lynch, C. C., List, A., Rodriguez, P. C., Blazar, B. R., Conejo-Garcia, J. R. & 3 others, Del Valle, J. R., Hu, C. C. & Anasetti, C., Jan 1 2018, In : Frontiers in immunology. 9, 1 p.

Research output: Contribution to journalArticle

Open Access
6 Scopus citations

Inhibition of inositol kinase B controls acute and chronic graft-versus-host disease

Thangavelu, G., Du, J., Paz, K. G., Loschi, M., Zaiken, M. C., Flynn, R., Taylor, P. A., Kirchmeier, A. K., Panoskaltsis-Mortari, A., Luznik, L., MacDonald, K. P., Hill, G. R., Maillard, I., Munn, D. H., Serody, J. S., Murphy, W. J., Miklos, D., Cutler, C. S., Koreth, J., Antin, J. H. & 5 others, Soiffer, R. J., Ritz, J., Dahlberg, C., Miller, A. T. & Blazar, B. R., Jan 1 2020, In : Blood. 135, 1, p. 28-40 13 p.

Research output: Contribution to journalArticle

Inhibition of pancreatic islet beta cell function by tumor necrosis factor is blocked by a soluble tumor necrosis factor receptor

Farney, A. C., Xenos, E., Sutherland, D. E. R., Widmer, M., Stephanian, E., Field, M. J., Kaufman, D. B., Stevens, R. B., Blazar, B., Platt, J. & Gores, P. F., Jan 1 1993, In : Transplantation proceedings. 25, 1 SUPPL. 1, p. 865-866 2 p.

Research output: Contribution to journalArticle

39 Scopus citations

Insights into the mechanism of FTY720 and compatibility with regulatory T cells for the inhibition of graft-versus-host disease (GVHD)

Taylor, P. A., Ehrhardt, M. J., Lees, C. J., Tolar, J., Weigel, B. J., Panoskaltsis-Mortari, A., Serody, J. S., Brinkmann, V. & Blazar, B. R., Nov 1 2007, In : Blood. 110, 9, p. 3480-3488 9 p.

Research output: Contribution to journalArticle

60 Scopus citations

In situ identification of allospecific B cells using pentamers

Panoskaltsis-Mortari, A., Taylor, P. A., Riddle, M. J., Shlomchik, M. A. & R.Blazar, B., Apr 1 2008, In : Blood. 111, 7, p. 3904-3905 2 p.

Research output: Contribution to journalLetter

2 Scopus citations

Interactions of keratinocyte growth factor with a nitrating species after marrow transplantation in mice

Haddad, I. Y., Panoskaltsis-Mortari, A., Ingbar, D. H., Resnik, E. R., Yang, S., Farrell, C. L., Lacey, D. L., Cornfield, D. N. & Blazar, B. R., Aug 1 1999, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 277, 2 21-2, p. L391-L400

Research output: Contribution to journalArticle

20 Scopus citations