1982 …2020

Research output per year

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Research Output

FoxP3 and Ezh2 regulate Tfr cell suppressive function and transcriptional program

Hou, S., Clement, R. L., Diallo, A., Blazar, B. R., Rudensky, A. Y., Sharpe, A. H. & Sage, P. T., Mar 1 2019, In : Journal of Experimental Medicine. 216, 3, p. 605-620 16 p.

Research output: Contribution to journalArticle

Open Access
11 Scopus citations
11 Scopus citations

Functional NK cell repertoires are maintained through IL-2Rα and fas ligand

Felices, M., Lenvik, T. R., Ankarlo, D. E. M., Foley, B., Curtsinger, J., Luo, X., Blazar, B. R., Anderson, S. K. & Miller, J. S., Apr 15 2014, In : Journal of Immunology. 192, 8, p. 3889-3897 9 p.

Research output: Contribution to journalArticle

15 Scopus citations

GASTRIC RECURRENCE OF ACUTE LYMPHOBLASTIC LEUKAEMIA MIMICKING GRAFT‐VERSUS‐HOST DISEASE

Weisdorf, D. J., Arthur, D., Rank, J., Blazar, B. R., Gajl‐Peczalska, K. & Snover, D., Apr 1989, In : British Journal of Haematology. 71, 4, p. 559-561 3 p.

Research output: Contribution to journalArticle

9 Scopus citations

Gastrointestinal cells of IL-7 receptor null mice exhibit increased sensitivity to irradiation

Welniak, L. A., Khaled, A. R., Anver, M. R., Komschlies, K. L., Wiltrout, R. H., Durum, S., Ruscetti, F. R., Blazar, B. R. & Murphy, W. J., Mar 1 2001, In : Journal of Immunology. 166, 5, p. 2923-2928 6 p.

Research output: Contribution to journalArticle

17 Scopus citations

GCNT1-mediated O-glycosylation of the sialomucin CD43 is a sensitive indicator of notch signaling in activated T cells

Perkey, E., De Sousa, D. M., Carrington, L., Chung, J., Dils, A., Granadier, D., Koch, U., Radtke, F., Ludewig, B., Blazar, B. R., Siebel, C. W., Brennan, T. V., Nolz, J., Labrecque, N. & Maillard, I., Mar 15 2020, In : Journal of Immunology. 204, 6, p. 1674-1688 15 p.

Research output: Contribution to journalArticle

6 Scopus citations

General strategies in in vivo animal modeling.

Vallera, D. A. & Blazar, B. R., 1992, In : Targeted diagnosis and therapy. 7, p. 63-77 15 p.

Research output: Contribution to journalReview article

Generation and function of progenitor t cells from stemregenin-1-expanded CD34+ human hematopoietic progenitor cells

Singh, J., Chen, E. L. Y., Xing, Y., Stefanski, H. E., Blazar, B. R. & Zúñiga-Pflücker, J. C., Jan 1 2019, In : Blood Advances. 3, 20, p. 2934-2948 15 p.

Research output: Contribution to journalArticle

Open Access

Generation and large-scale expansion of human inducible regulatory T cells that suppress graft-versus-host disease

Hippen, K. L., Merkel, S. C., Schirm, D. K., Nelson, C., Tennis, N. C., Riley, J. L., June, C. H., Miller, J. S., Wagner, J. E. & Blazar, B. R., Jun 1 2011, In : American Journal of Transplantation. 11, 6, p. 1148-1157 10 p.

Research output: Contribution to journalArticle

150 Scopus citations

Gene therapy of murine solid tumors with T cells transduced with a retroviral vascular endothelial growth factor-immunotoxin target gene

Jin, N., Chen, W., Blazar, B. R., Ramakrishnan, S. & Vallera, D. A., Apr 6 2002, In : Human gene therapy. 13, 4, p. 497-508 12 p.

Research output: Contribution to journalArticle

23 Scopus citations

Genetic and immunological parameters governing in vivo susceptibility/resistance to retrovirally induced murine malignant histiocytosis

Panoskaltsis-Mortari, A., Egeler, R. M., Yaeger, T. M., Yoneji, S., Schmitz, L., Lilly, F., Nesbit, M. E. & Blazar, B. R., Oct 1998, In : Journal of Leukocyte Biology. 64, 4, p. 441-450 10 p.

Research output: Contribution to journalArticle

4 Scopus citations

Genetic trickery - Escape of leukemia from immune attack

Barrett, J. & Blazar, B. R., Jul 30 2009, In : New England Journal of Medicine. 361, 5, p. 524-525 2 p.

Research output: Contribution to journalEditorial

5 Scopus citations
2 Scopus citations

Graft Versus Host Disease after Liver Transplantation in Adults: A Case series, Review of Literature, and an Approach to Management

Murali, A. R., Chandra, S., Stewart, Z., Blazar, B. R., Farooq, U., Ince, M. N. & Dunkelberg, J., Dec 1 2016, In : Transplantation. 100, 12, p. 2661-2670 10 p.

Research output: Contribution to journalArticle

Open Access
21 Scopus citations

Graft-versus-host disease of the CNS is mediated by TNF upregulation in microglia

Mathew, N. R., Vinnakota, J. M., Apostolova, P., Erny, D., Hamarsheh, S., Andrieux, G., Kim, J. S., Hanke, K., Goldmann, T., Chappell-Maor, L., El-Khawanky, N., Ihorst, G., Schmidt, D., Duyster, J., Finke, J., Blank, T., Boerries, M., Blazar, B. R., Jung, S., Prinz, M. & 1 others, Zeiser, R., Mar 2 2020, In : Journal of Clinical Investigation. 130, 3, p. 1315-1329 15 p.

Research output: Contribution to journalArticle

Open Access

Graft-versus-host disease prevention in allogeneic bone marrow transplantation from histocompatible siblings: A pilot study using immunotoxins form cell depletion of donor bone marrow

Filipovich, A. H., Vallera, D. A., Youle, R. J., Haake, R., Blazar, B. R., Arthur, D., Neville, D. M., Ramsay, N. K. C., McGlave, P. & Kersey, J. H., Jul 1987, In : Transplantation. 44, 1, p. 62-69 8 p.

Research output: Contribution to journalArticle

67 Scopus citations

GSK3 inhibition drives maturation of NK cells and enhances their antitumor activity

Cichocki, F. M., Valamehr, B., Bjordahl, R., Zhang, B., Rezner, B., Rogers, P., Gaidarova, S., Moreno, S., Tuininga, K., Dougherty, P., McCullar, V., Howard, P., Sarhan, D., Taras, E., Schlums, H., Abbot, S., Shoemaker, D., Bryceson, Y. T., Blazar, B. R., Wolchko, S. & 2 others, Cooley, S. A. & Miller, J. S., Oct 15 2017, In : Cancer Research. 77, 20, p. 5664-5675 12 p.

Research output: Contribution to journalArticle

Open Access
28 Scopus citations

GVHD after haploidentical transplantation: A novel, MHC-defined rhesus macaque model identifies CD28- CD8+ T cells as a reservoir of breakthrough T-cell proliferation during costimulation blockade and sirolimus-based immunosuppression

Miller, W. P., Srinivasan, S., Panoskaltsis-Mortari, A., Singh, K., Sen, S., Hamby, K., Deane, T., Stempora, L., Beus, J., Turner, A., Wheeler, C., Anderson, D. C., Sharma, P., Garcia, A., Strobert, E., Elder, E., Crocker, I., Crenshaw, T., Penedo, M. C. T., Ward, T. & 5 others, Song, M., Horan, J., Larsen, C. P., Blazar, B. R. & Kean, L. S., Dec 9 2010, In : Blood. 116, 24, p. 5403-5417 15 p.

Research output: Contribution to journalArticle

33 Scopus citations

GVHD-associated, inflammasome-mediated loss of function in adoptively transferred myeloid-derived suppressor cells

Koehn, B. H., Apostolova, P., Haverkamp, J. M., Miller, J. S., McCullar, V., Tolar, J., Munn, D. H., Murphy, W. J., Brickey, W. J., Serody, J. S., Gabrilovich, D. I., Bronte, V., Murray, P. J., Ting, J. P. Y., Zeiser, R. & Blazar, B. R., Sep 24 2015, In : Blood. 126, 13, p. 1621-1628 8 p.

Research output: Contribution to journalArticle

47 Scopus citations

GVHD prevents NK-cell-dependent leukemia and virus-specific innate immunity

Bunting, M. D., Varelias, A., Souza-Fonseca-Guimaraes, F., Schuster, I. S., Lineburg, K. E., Kuns, R. D., Fleming, P., Locke, K. R., Huntington, N. D., Blazar, B. R., Lane, S. W., Tey, S. K., MacDonald, K. P. A., Smyth, M. J., Degli-Esposti, M. A. & Hill, G. R., Feb 2 2017, In : Blood. 129, 5, p. 630-642 13 p.

Research output: Contribution to journalArticle

Open Access
16 Scopus citations
Open Access
15 Scopus citations

Helminth-Induced Production of TGF-b and Suppression of Graft-versus-Host Disease Is Dependent on IL-4 Production by Host Cells

Li, Y., Guan, X., Liu, W., Chen, H. L., Beyatli, S., Metwali, A., Weiner, G. J., Zavazava, N., Blumberg, R. S., Urban, J. F., Blazar, B. R., Elliott, D. E. & Ince, M. N., Nov 15 2018, In : Journal of Immunology. 201, 10, p. 2910-2922 13 p.

Research output: Contribution to journalArticle

Open Access

Hematopoietic Cell Therapy for Metabolic Disease

Orchard, P. J., Blazar, B. R., Wagner, J., Charnas, L., Krivit, W. & Tolar, J., Oct 1 2007, In : Journal of Pediatrics. 151, 4, p. 340-346 7 p.

Research output: Contribution to journalArticle

62 Scopus citations
64 Scopus citations

Hematopoietic growth factors for graft failure after bone marrow transplantation: A randomized trial of granulocyte-macrophage colony- stimulating factor (GM-CSF) versus sequential GM-CSF plus granulocyte-CSF

Weisdorf, D. J., Verfaillie, C. M., Davies, S. M., Filipovich, A. H., Wagner, J. E., Miller, J. S., Burroughs, J., Ramsay, N. K. C., Kersey, J. H., McGlave, P. B. & Blazar, B. R., Jan 1 1995, In : Blood. 85, 12, p. 3452-3456 5 p.

Research output: Contribution to journalArticle

53 Scopus citations

Hematopoietic progenitor cell regulation by CD4+CD25+ T cells

Urbieta, M., Barao, I., Jones, M., Jurecic, R., Panoskaltsis-Mortari, A., Blazar, B. R., Murphy, W. J. & Levy, R. B., Jun 10 2010, In : Blood. 115, 23, p. 4934-4943 10 p.

Research output: Contribution to journalArticle

25 Scopus citations

Hematopoietic reconstitution by multipotent adult progenitor cells: Precursors to long-term hematopoietic stem cells

Serafini, M., Dylla, S. J., Oki, M., Heremans, Y., Tolar, J., Jiang, Y., Buckley, S. M., Pelacho, B., Burns, T. C., Frommer, S., Rossi, D. J., Bryder, D., Panoskaltsis-Mortari, A., O'Shaughnessy, M. J., Nelson-Holte, M., Fine, G. C., Weissman, I. L., Blazar, B. R. & Verfaillie, C. M., Jan 22 2007, In : Journal of Experimental Medicine. 204, 1, p. 129-139 11 p.

Research output: Contribution to journalArticle

89 Scopus citations

Higher therapeutic CsA levels early post transplantation reduce risk of acute GVHD and improves survival

Rogosheske, J. R., Fargen, A. D., Defor, T. E., Warlick, E., Arora, M., Blazar, B. R., Weisdorf, D. J. & Brunstein, C. G., Jan 1 2014, In : Bone marrow transplantation. 49, 1, p. 122-125 4 p.

Research output: Contribution to journalArticle

22 Scopus citations

High spontaneous IL-10 production in unrelated bone marrow transplant recipients is associated with fewer transplant-related complications and early deaths

Baker, K. S., Roncarolo, M. G., Peters, C., Bigler, M., De For, T. E. & Blazar, B. R., Jan 1 1999, In : Bone marrow transplantation. 23, 11, p. 1123-1129 7 p.

Research output: Contribution to journalArticle

65 Scopus citations

Homeostatic expansion occurs independently of costimulatory signals

Prlic, M., Blazar, B. R., Khoruts, A., Zell, T. & Jameson, S. C., Nov 15 2001, In : Journal of Immunology. 167, 10, p. 5664-5668 5 p.

Research output: Contribution to journalArticle

93 Scopus citations

Host factors that impact the biodistribution and persistence of multipotent adult progenitor cells

Tolar, J., O'Shaughnessy, M. J., Panoskaltsis-Mortari, A., McElmurry, R. T., Bell, S., Riddle, M., McIvor, R. S., Yant, S. R., Kay, M. A., Krause, D., Verfaillie, C. M. & Blazar, B. R., May 15 2006, In : Blood. 107, 10, p. 4182-4188 7 p.

Research output: Contribution to journalArticle

65 Scopus citations

Host programmed death ligand 1 is dominant over programmed death ligand 2 expression in regulating graft-versus-host disease lethality

Saha, A., Aoyama, K., Taylor, P. A., Koehn, B. H., Veenstra, R. G., Panoskaltsis-Mortari, A., Munn, D. H., Murphy, W. J., Azuma, M., Yagita, H., Fife, B. T., Sayegh, M. H., Najafian, N., Socie, G., Ahmed, R., Freeman, G. J., Sharpe, A. H. & Blazar, B. R., 2013, In : Blood. 122, 17, p. 3062-3073 12 p.

Research output: Contribution to journalArticle

103 Scopus citations

Host T cells resist graft-versus-host disease mediated by donor leukocyte infusions

Blazar, B. R., Lees, C. J., Martin, P. J., Noelle, R. J., Kwon, B., Murphy, W. & Taylor, P. A., Nov 1 2000, In : Journal of Immunology. 165, 9, p. 4901-4909 9 p.

Research output: Contribution to journalArticle

62 Scopus citations

How ibrutinib, a B-cell malignancy drug, became an FDA-approved second-line therapy for steroid-resistant chronic GVHD

Jaglowski, S. M. & Blazar, B. R., Aug 14 2018, In : Blood Advances. 2, 15, p. 2012-2019 8 p.

Research output: Contribution to journalArticle

Open Access
16 Scopus citations

Human CD19-Targeted Mouse T Cells Induce B Cell Aplasia and Toxicity in Human CD19 Transgenic Mice

Pennell, C. A., Barnum, J. L., McDonald-Hyman, C. S., Panoskaltsis-Mortari, A., Riddle, M. J., Xiong, Z., Loschi, M., Thangavelu, G., Campbell, H. M., Storlie, M. D., Refaeli, Y., Furlan, S. N., Jensen, M. C., Kean, L. S., Miller, J. S., Tolar, J., Osborn, M. J. & Blazar, B. R., Jun 6 2018, In : Molecular Therapy. 26, 6, p. 1423-1434 12 p.

Research output: Contribution to journalArticle

Open Access
12 Scopus citations
59 Scopus citations

Human group 3 innate lymphoid cells express DR3 and respond to TL1A with enhanced IL-22 production and IL-2-dependent proliferation

Ahn, Y. O., Weeres, M. A., Neulen, M. L., Choi, J., Kang, S. H., Heo, D. S., Bergerson, R., Blazar, B. R., Miller, J. S. & Verneris, M. R., Aug 1 2015, In : European Journal of Immunology. 45, 8, p. 2335-2342 8 p.

Research output: Contribution to journalArticle

17 Scopus citations

Human in vitro-induced regulatory T cells display Dlgh1dependent and PKC-θ restrained suppressive activity

Zanin-Zhorov, A., Kumari, S., Hippen, K. L., Merkel, S. C., MacMillan, M. L., Blazar, B. R. & Dustin, M. L., Dec 1 2017, In : Scientific reports. 7, 1, 4258.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Human plasmacytoid dendritic cells activated by CpG oligodeoxynucleotides induce the generation of CD4+CD25+ regulatory T cells

Moseman, E. A., Liang, X., Dawson, A. J., Panoskaltsis-Mortari, A., Krieg, A. M., Liu, Y. J., Blazar, B. R. & Chen, W., Oct 1 2004, In : Journal of Immunology. 173, 7, p. 4433-4442 10 p.

Research output: Contribution to journalArticle

502 Scopus citations
34 Scopus citations

Human T Regulatory Cell Therapy: Take a Billion or So and Call Me in the Morning

Riley, J. L., June, C. H. & Blazar, B. R., May 22 2009, In : Immunity. 30, 5, p. 656-665 10 p.

Research output: Contribution to journalReview article

318 Scopus citations

Ibrutinib for chronic graft-versus-host disease after failure of prior therapy

Miklos, D., Cutler, C. S., Arora, M., Waller, E. K., Jagasia, M., Pusic, I., Flowers, M. E., Logan, A. C., Nakamura, R., Blazar, B. R., Li, Y., Chang, S., Lal, I., Dubovsky, J., James, D. F., Styles, L. & Jaglowski, S., Nov 23 2017, In : Blood. 130, 21, p. 2243-2250 8 p.

Research output: Contribution to journalArticle

Open Access
97 Scopus citations

Ibrutinib treatment ameliorates murine chronic graft-versus-host disease

Dubovsky, J. A., Flynn, R., Du, J., Harrington, B. K., Zhong, Y., Kaffenberger, B., Yang, C., Towns, W. H., Lehman, A., Johnson, A. J., Muthusamy, N., Devine, S. M., Jaglowski, S., Serody, J. S., Murphy, W. J., Munn, D. H., Luznik, L., Hill, G. R., Wong, H. K., MacDonald, K. K. P. & 10 others, Maillard, I., Koreth, J., Elias, L., Cutler, C., Soiffer, R. J., Antin, J. H., Ritz, J., Panoskaltsis-Mortari, A., Byrd, J. C. & Blazar, B. R., Nov 3 2014, In : Journal of Clinical Investigation. 124, 11, p. 4867-4876 10 p.

Research output: Contribution to journalArticle

91 Scopus citations

Identification of cellular sources of IL-2 needed for regulatory T cell development and homeostasis

Owen, D. L., Mahmud, S. A., Vang, K. B., Kelly, R. M., Blazar, B. R., Smith, K. A. & Farrar, M. A., Jun 15 2018, In : Journal of Immunology. 200, 12, p. 3926-3933 8 p.

Research output: Contribution to journalArticle

Open Access
17 Scopus citations
6 Scopus citations

IDO in Human Gut Graft-versus-Host Disease

Ratajczak, P., Janin, A., Peffault de Larour, R., Koch, L., Roche, B., Munn, D., Blazar, B. R. & Socié, G., Jan 1 2012, In : Biology of Blood and Marrow Transplantation. 18, 1, p. 150-155 6 p.

Research output: Contribution to journalArticle

17 Scopus citations

IFN-γ mediates CD4+ T-cell loss and impairs secondary antitumor responses after successful initial immunotherapy

Berner, V., Liu, H., Zhou, Q., Alderson, K. L., Sun, K., Weiss, J. M., Back, T. C., Longo, D. L., Blazar, B. R., Wiltrout, R. H., Welniak, L. A., Redelman, D. & Murphy, W. J., Mar 2007, In : Nature Medicine. 13, 3, p. 354-360 7 p.

Research output: Contribution to journalArticle

110 Scopus citations