1982 …2020

Research output per year

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Research Output

26 Scopus citations

Effects of donor T-cell trafficking and priming site on graft-versus-host disease induction by naive and memory phenotype CD4 T cells

Anderson, B. E., Taylor, P. A., McNiff, J. M., Jain, D., Demetris, A. J., Panoskaltsis-Mortari, A., Ager, A., Blazar, B. R., Shlomchik, W. D. & Shlomchik, M. J., May 15 2008, In : Blood. 111, 10, p. 5242-5251 10 p.

Research output: Contribution to journalArticle

59 Scopus citations

Effects of MicroRNA on regulatory T Cells and implications for adoptive cellular therapy to ameliorate graft-versus-host disease

Hippen, K. L., Loschi, M., Nicholls, J., MacDonald, K. P. A. & Blazar, B. R., Jan 31 2018, In : Frontiers in immunology. 9, JAN, 57.

Research output: Contribution to journalShort survey

Open Access
12 Scopus citations

Effects of oxidant stress on inflammation and survival of iNOS knockout mice after marrow transplantation

Yang, S., Porter, V. A., Cornfield, D. N., Milla, C., Panoskaltsis-Mortari, A., Blazar, B. R. & Haddad, I. Y., Oct 20 2001, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 281, 4 25-4, p. L922-L930

Research output: Contribution to journalArticle

23 Scopus citations

Efficacy, durability, and response predictors of low-dose interleukin-2 therapy for chronic graft-versus-host disease

Koreth, J., Kim, H. T., Jones, K. T., Lange, P. B., Reynolds, C. G., Chammas, M. J., Dusenbury, K., Whangbo, J., Nikiforow, S., Alyea, E. P., Armand, P., Cutler, C. S., Ho, V. T., Chen, Y. B., Avigan, D., Blazar, B. R., Antin, J. H., Ritz, J. & Soiffer, R. J., Jul 7 2016, In : Blood. 128, 1, p. 130-137 8 p.

Research output: Contribution to journalArticle

Open Access
78 Scopus citations

Efficacy and immunologic effects of extracorporeal photopheresis plus interleukin-2 in chronic graft-versus-host disease

Belizaire, R., Kim, H. T., Poryanda, S. J., Mirkovic, N. V., Hipolito, E., Savage, W. J., Reynolds, C. G., Fields, M. J., Whangbo, J., Kubo, T., Nikiforow, S., Alyea, E. P., Armand, P., Cutler, C. S., Ho, V. T., Blazar, B. R., Antin, J. H., Ritz, J., Soiffer, R. J. & Koreth, J., Apr 9 2019, In : Blood Advances. 3, 7, p. 969-979 11 p.

Research output: Contribution to journalArticle

Open Access
7 Scopus citations

Elevation of Intracellular Cyclic AMP in Alloreactive CD4+ T Cells Induces Alloantigen-Specific Tolerance That Can Prevent GVHD Lethality In Vivo

O'Shaughnessy, M. J., Chen, Z. M., Gramaglia, I., Taylor, P. A., Panoskaltsis-Mortari, A., Vogtenhuber, C., Palmer, E., Grader-Beck, T., Boussiotis, V. A. & Blazar, B. R., May 1 2007, In : Biology of Blood and Marrow Transplantation. 13, 5, p. 530-542 13 p.

Research output: Contribution to journalArticle

17 Scopus citations

Embryonic pig pancreatic tissue transplantation for the treatment of diabetes

Eventov-Friedman, S., Tchorsh, D., Katchman, H., Shezen, E., Aronovich, A., Hecht, G., Dekel, B., Rechavi, G., Blazar, B. R., Feine, I., Tal, O., Freud, E. & Reisner, Y., 2006, In : PLoS Medicine. 3, 7, p. 1165-1177 13 p.

Research output: Contribution to journalArticle

47 Scopus citations

Emerging strategies to boost thymic function

Holländer, G. A., Krenger, W. & Blazar, B. R., Aug 1 2010, In : Current Opinion in Pharmacology. 10, 4, p. 443-453 11 p.

Research output: Contribution to journalReview article

48 Scopus citations

Endogenous IL-2 production by natural killer cells maintains cytotoxic and proliferative capacity following retroviral-mediated gene transfer

Miller, J. S., Tessmer-Tuck, J., Blake, N., Lund, J., Scott, A., Blazar, B. R. & Orchard, P. J., Oct 27 1997, In : Experimental Hematology. 25, 11, p. 1140-1148 9 p.

Research output: Contribution to journalArticle

23 Scopus citations

Endothelial cell expression of tissue factor in sickle mice is augmented by hypoxia/reoxygenation and inhibited by lovastatin

Solovey, A., Kollander, R., Shet, A., Milbauer, L. C., Choong, S., Panoskaltsis-Mortari, A., Blazar, B. R., Kelm, R. J. & Hebbel, R. P., Aug 1 2004, In : Blood. 104, 3, p. 840-846 7 p.

Research output: Contribution to journalArticle

144 Scopus citations

Engineering lymphocyte subsets: Tools, trials and tribulations

June, C. H., Blazar, B. R. & Riley, J. L., Oct 1 2009, In : Nature Reviews Immunology. 9, 10, p. 704-716 13 p.

Research output: Contribution to journalReview article

158 Scopus citations

Engraftment of severe combined immune deficient mice receiving allogeneic bone marrow via in utero or postnatal transfer

Blazar, B. R., Taylor, P. A., McElmurry, R., Tian, L., Panoskaltsis-Mortari, A., Lam, S., Lees, C., Waldschmidt, T. & Vallera, D. A., Nov 15 1998, In : Blood. 92, 10, p. 3949-3959 11 p.

Research output: Contribution to journalArticle

82 Scopus citations
Open Access
19 Scopus citations

Eomesodermin promotes the development of type 1 regulatory T (TR1) cells

Zhang, P., Lee, J. S., Gartlan, K. H., Schuster, I. S., Comerford, I., Varelias, A., Ullah, M. A., Vuckovic, S., Koyama, M., Kuns, R. D., Locke, K. R., Beckett, K. J., Olver, S. D., Samson, L. D., de Oca, M. M., Rivera, F. D. L., Clouston, A. D., Belz, G. T., Blazar, B. R., MacDonald, K. P. & 7 others, McColl, S. R., Thomas, R., Engwerda, C. R., Degli-Esposti, M. A., Kallies, A., Tey, S. K. & Hill, G. R., 2017, In : Science Immunology. 2, 10, eaah7152.

Research output: Contribution to journalArticle

Open Access
42 Scopus citations

Epstein-Barr virus associated B cell lymphoproliferative disorders following bone marrow transplantation

Shapiro, R. S., McCLain, K., Frizzera, G., Gajl-Peczalska, K. J., Kersey, J. H., Blazar, B. R., Arthur, D. C., Patton, D. F., Greenberg, J. S., Burke, B., Ramsay, N. K. C., McGlave, P. & Filipovich, A. H., Jan 1 1988, In : Blood. 71, 5, p. 1234-1243 10 p.

Research output: Contribution to journalArticle

Open Access
427 Scopus citations
Open Access

Erratum: Inhibition of acute graft-versus-host disease with retention of graft-versus-tumor effects by the proteasome inhibitor bortezomib (Proceedings of the National Academy of Sciences of the United States of America (May 25, 2004) 101, 21 (8120-8125))

Sun, K., Welniak, L. A., Panoskaltsis-Mortari, A., O'Shaughnessy, M. J., Liu, H., Barao, I., Riordan, W., Sitcheran, R., Wysocki, C., Serody, J. S., Blazar, B. R., Sayers, T. J. & Murphy, W. J., Aug 24 2004, In : Proceedings of the National Academy of Sciences of the United States of America. 101, 34, 1 p.

Research output: Contribution to journalComment/debate

1 Scopus citations

Erratum: B7 expression on T cells down-regulates immune responses through CTLA-4 ligation via R-T interactions (Journal of Immunology (2004) 172 (34-39))

Taylor, P. A., Lees, C. J., Fournier, S., Allison, J. P., Sharpe, A. H. & Blazar, B. R., Aug 1 2004, In : Journal of Immunology. 173, 3, 1 p.

Research output: Contribution to journalComment/debate

Erratum: Hematopoietic reconstitution by multipotent adult progenitor cells: Precursors to long-term hematopoietic stem cells (Journal of Experimental Medicine (January 22, 2007) 204, 1, (129-139)

Serafini, M., Dylla, S. J., Oki, M., Heremans, Y., Tolar, J., Jiang, Y., Buckley, S. M., Pelacho, B., Burns, T. C., Frommer, S., Rossi, D. J., Bryder, D., Panoskaltsis-Mortari, A., O'Shaughnessy, M. J., Nelson-Holte, M., Fine, G. C., Weissman, I. L., Blazar, B. R. & Verfaillie, C. M., Jul 9 2007, In : Journal of Experimental Medicine. 204, 7, 1 p.

Research output: Contribution to journalComment/debate

Erythropoietin receptor-mediated molecular crosstalk promotes T cell immunoregulation and transplant survival

Purroy, C., Fairchild, R. L., Tanaka, T., Baldwin, W. M., Manrique, J., Madsen, J. C., Colvin, R. B., Alessandrini, A., Blazar, B. R., Fribourg, M., Donadei, C., Maggiore, U., Heeger, P. S. & Cravedi, P., Aug 2017, In : Journal of the American Society of Nephrology. 28, 8, p. 2377-2392 16 p.

Research output: Contribution to journalArticle

Open Access
17 Scopus citations

Evaluation of innate and adaptive immunity contributing to the antitumor effects of PD1 blockade in an orthotopic murine model of pancreatic cancer

D'Alincourt Salazar, M., Manuel, E. R., Tsai, W., D'Apuzzo, M., Goldstein, L., Blazar, B. R. & Diamond, D. J., Jun 2 2016, In : OncoImmunology. 5, 6, e1160184.

Research output: Contribution to journalArticle

Open Access
8 Scopus citations

Evaluation of KIR ligand incompatibility in mismatched unrelated donor hematopoietic transplants

Davies, S. M., Ruggieri, L., DeFor, T., Wagner, J. E., Weisdorf, D. J., Miller, J. S., Velardi, A. & Blazar, B. R., Nov 15 2002, In : Blood. 100, 10, p. 3825-3827 3 p.

Research output: Contribution to journalArticle

307 Scopus citations

Evaluation of TCR gene editing achieved by TALENs, CRISPR/Cas9, and megaTAL nucleases

Osborn, M. J., Webber, B. R., Knipping, F., Lonetree, C. L., Tennis, N., DeFeo, A. P., McElroy, A. N., Starker, C. G., Lee, C., Merkel, S., Lund, T. C., Kelly-Spratt, K. S., Jensen, M. C., Voytas, D. F., Von Kalle, C., Schmidt, M., Gabriel, R., Hippen, K. L., Miller, J. S., Scharenberg, A. M. & 2 others, Tolar, J. & Blazar, B. R., Mar 1 2016, In : Molecular Therapy. 24, 3, p. 570-581 12 p.

Research output: Contribution to journalArticle

Open Access
78 Scopus citations

Evidence for early fibrosis and increased airway resistance in bone marrow transplant recipient mice deficient in MMP12

England, K. A., Price, A. P., Tram, K. V., Shapiro, S. D., Blazar, B. R. & Panoskaltsis-Mortari, A., Oct 1 2011, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 301, 4, p. L519-L526

Research output: Contribution to journalArticle

14 Scopus citations

Expanded nonhuman primate Tregs exhibit a unique gene expression signature and potently downregulate alloimmune responses

Anderson, A., Martens, C. L., Hendrix, R., Stempora, L. L., Miller, W. P., Hamby, K., Russell, M., Strobert, E., Blazar, B. R., Pearson, T. C., Larsen, C. P. & Kean, L. S., Nov 1 2008, In : American Journal of Transplantation. 8, 11, p. 2252-2264 13 p.

Research output: Contribution to journalArticle

17 Scopus citations
34 Scopus citations

Experimental animal models in the study of GVL reactions

Truitt, R. L., Johnson, B. D., Korngold, R., Townsend, R. & Blazar, B. R., Jan 1 2000, Allogeneic Immunotherapy for Malignant Diseases. CRC Press, p. 39-74 36 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations

Expression of telomerase and telomere length are unaffected by either age or limb regeneration in Danio rerio

Lund, T. C., Glass, T. J., Tolar, J. & Blazar, B. R., Nov 6 2009, In : PloS one. 4, 11, e7688.

Research output: Contribution to journalArticle

37 Scopus citations

Exuberant inflammation in nicotinamide adenine dinucleotide phosphate-oxidase-deficient mice after allogeneic marrow transplantation

Yang, S., Panoskaltsis-Mortari, A., Shukla, M., Blazar, B. R. & Haddad, I. Y., Jun 1 2002, In : Journal of Immunology. 168, 11, p. 5840-5847 8 p.

Research output: Contribution to journalArticle

20 Scopus citations

Ex vivo depletion of alloreactive cells based on CFSE dye dilution, activation antigen selection, and dendritic cell stimulation

Godfrey, W. R., Krampf, M. R., Taylor, P. A. & Blazar, B. R., Feb 1 2004, In : Blood. 103, 3, p. 1158-1165 8 p.

Research output: Contribution to journalArticle

72 Scopus citations

Ex vivo expanded non-human primate regulatory t cells suppress xeno-antigenic responses through both cytokine-and contact-dependent pathways

Johnson, J. L., Hennessy, E. A., Pahuja, A., Graham, M., Blazar, B. R., Hering, B. J. & Bansal-Pakala, P., 2009, In : Xenotransplantation. 16, 5, p. 387 1 p.

Research output: Contribution to journalArticle

Ex Vivo Expanded Treg Therapy Promotes Long-Term Islet Allograft Survival in a Non-Human Primate Model

Bansal-Pakala, P., Pahuja, A., Hennessey, E., Graham, M., Hering, B. J. & Blazar, B. R., 2011, In : American Journal of Transplantation. 11, p. 209 1 p.

Research output: Contribution to journalArticle

Ex vivo fucosylation of third-party human regulatory T cells enhances anti-graft-versus-host disease potency in vivo

Parmar, S., Liu, X., Najjar, A., Shah, N., Yang, H., Yvon, E., Rezvani, K., McNiece, I., Zweidler-McKay, P., Miller, L., Wolpe, S., Blazar, B. R. & Shpall, E. J., Jan 1 2015, In : Blood. 125, 9, p. 1502-1506 5 p.

Research output: Contribution to journalArticle

34 Scopus citations

Ex vivo inhibition of NF-κB signaling in alloreactive T-cells prevents graft-versus-host disease

O'Shaughnessy, M. J., Vogtenhuber, C., Sun, K., Sitcheran, R., Baldwin, A. S., Murphy, W. J., Dang, L., Jaffee, B., Palmer, E., Serody, J. S. & Blazar, B. R., Mar 1 2009, In : American Journal of Transplantation. 9, 3, p. 452-462 11 p.

Research output: Contribution to journalArticle

14 Scopus citations
Open Access

Factors affecting thymic function after allogeneic hematopoietic stem cell transplantation

Weinberg, K., Blazar, B. R., Wagner, J. E., Agura, E., Hill, B. J., Smogorzewska, M., Koup, R. A., Betts, M. R., Collins, R. H. & Douek, D. C., Mar 1 2001, In : Blood. 97, 5, p. 1458-1466 9 p.

Research output: Contribution to journalArticle

343 Scopus citations
48 Scopus citations

Fanconi anemia gene editing by the CRISPR/Cas9 system

Osborn, M. J., Gabriel, R., Webber, B. R., Defeo, A. P., McElroy, A. N., Jarjour, J., Starker, C. G., Wagner, J. E., Joung, J. K., Voytas, D. F., Von Kalle, C., Schmidt, M., Blazar, B. R. & Tolar, J., Feb 1 2015, In : Human gene therapy. 26, 2, p. 114-126 13 p.

Research output: Contribution to journalArticle

74 Scopus citations

Fibroblastic niches prime T cell alloimmunity through Delta-like Notch ligands

Ebens, C. L., Chung, J., Perkey, E., Radojcic, V., Koch, U., Scarpellino, L., Tong, A., Allen, F., Wood, S., Feng, J., Friedman, A., Granadier, D., Tran, I. T., Chai, Q., Onder, L., Yan, M., Reddy, P., Blazar, B. R., Huang, A. Y., Brennan, T. V. & 6 others, Bishop, D. K., Ludewig, B., Siebel, C. W., Radtke, F., Luther, S. A. & Maillard, I., Apr 3 2017, In : Journal of Clinical Investigation. 127, 4, p. 1574-1588 15 p.

Research output: Contribution to journalArticle

Open Access
27 Scopus citations

First-in-human phase 1 clinical study of the IL-15 superagonist complex ALT-803 to treat relapse after transplantation

Romee, R., Cooley, S., Berrien-Elliott, M. M., Westervelt, P., Verneris, M. R., Wagner, J. E., Weisdorf, D. J., Blazar, B. R., Ustun, C., DeFor, T. E., Vivek, S., Peck, L., DiPersio, J. F., Cashen, A. F., Kyllo, R., Musiek, A., Schaffer, A., Anadkat, M. J., Rosman, I., Miller, D. & 6 others, Egan, J. O., Jeng, E. K., Rock, A., Wong, H. C., Fehniger, T. A. & Miller, J. S., Jun 7 2018, In : Blood. 131, 23, p. 2515-2527 13 p.

Research output: Contribution to journalArticle

Open Access
87 Scopus citations

First-in-human trial of rhIL-15 and haploidentical natural killer cell therapy for advanced acute myeloid leukemia

Cooley, S., He, F., Bachanova, V., Vercellotti, G. M., DeFor, T. E., Curtsinger, J. M., Robertson, P., Grzywacz, B., Conlon, K. C., Waldmann, T. A., McKenna, D. H., Blazar, B. R., Weisdorf, D. J. & Miller, J. S., 2019, In : Blood Advances. 3, 13, p. 1970-1980 11 p.

Research output: Contribution to journalArticle

Open Access
16 Scopus citations

FK506 (Tacrolimus) monotherapy for prevention of graft-versus-host disease after histocompatible sibling allogeneic bone marrow transplantation

Fay, J. W., Wingard, J. R., Antin, J. H., Collins, R. H., Piñeiro, L. A., Blazar, B. R., Saral, R., Bierer, B. E., Przepiorka, D., Fitzsimmons, W. E., Maher, R. M. & Weisdorf, D. J., Apr 15 1996, In : Blood. 87, 8, p. 3514-3519 6 p.

Research output: Contribution to journalArticle

Open Access
93 Scopus citations
25 Scopus citations
31 Scopus citations
31 Scopus citations

Flt3 ligand antitumor activity in a murine breast cancer model: A comparison with granulocyte-macrophage colony-stimulating factor and a potential mechanism of action

Braun, S. E., Chen, K., Blazar, B. R., Orchard, P. J., Sledge, G., Robertson, M. J., Broxmeyer, H. E. & Cornetta, K., Sep 1 1999, In : Human gene therapy. 10, 13, p. 2141-2151 11 p.

Research output: Contribution to journalArticle

39 Scopus citations
13 Scopus citations

Follicular regulatory T cells control humoral and allergic immunity by restraining early B cell responses

Clement, R. L., Daccache, J., Mohammed, M. T., Diallo, A., Blazar, B. R., Kuchroo, V. K., Lovitch, S. B., Sharpe, A. H. & Sage, P. T., Oct 1 2019, In : Nature immunology. 20, 10, p. 1360-1371 12 p.

Research output: Contribution to journalArticle

Open Access
18 Scopus citations