1982 …2020

Research output per year

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Research Output

Cytokine-primed bone marrow stem cells vs. peripheral blood stem cells for autologous transplantation: A randomized comparison of GM-CSF vs. G-CSF

Weisdorf, D., Miller, J., Verfaillie, C., Bums, L., Wagner, J., Blazar, B., Davies, S., Miller, W., Hannan, P., Steinbuch, M., Ramsay, N. & McGlave, P., Oct 1 1997, In : Biology of Blood and Marrow Transplantation. 3, 4, p. 217-223 7 p.

Research output: Contribution to journalReview article

34 Scopus citations

Cytokines in liposomes: Preliminary studies with IL-1, IL-2, IL-6, GM-CSF and interferon-γ

Anderson, P. M., Hanson, D. C., Hasz, D. E., Halet, M. R., Blazar, B. R. & Ochoa, A. C., Jan 1994, In : Cytokine. 6, 1, p. 92-101 10 p.

Research output: Contribution to journalArticle

79 Scopus citations

Cytotoxic T cells reactive to an immunodominant leukemia-associated antigen can be specifically primed and expanded by combining a specific priming step with nonspecific large-scale expansion

Ghosh, A., Wolenski, M., Klein, C., Welte, K., Blazar, B. R. & Sauer, M. G., Feb 1 2008, In : Journal of Immunotherapy. 31, 2, p. 121-131 11 p.

Research output: Contribution to journalArticle

12 Scopus citations

Danger-associated extracellular ATP counters MDSC therapeutic efficacy in acute GVHD

Koehn, B. H., Saha, A., McDonald-Hyman, C., Loschi, M., Thangavelu, G., Ma, L., Zaiken, M., Dysthe, J., Krepps, W., Panthera, J., Hippen, K., Jameson, S. C., Miller, J. S., Cooper, M. A., Farady, C. J., Iwawaki, T., Ting, J. P. Y., Serody, J. S., Murphy, W. J., Hill, G. R. & 5 others, Murray, P. J., Bronte, V., Munn, D. H., Zeiser, R. & Blazar, B. R., Nov 7 2019, In : Blood. 134, 19, p. 1670-1682 13 p.

Research output: Contribution to journalArticle

4 Scopus citations

Delayed immune reconstitution after allogeneic transplantation increases the risks of mortality and chronic GVHD

Bejanyan, N., Brunstein, C. G., Cao, Q., Lazaryan, A., Luo, X., Curtsinger, J. M., Mehta, R. S., Warlick, E. D., Cooley, S. A., Blazar, B. R., Miller, J. S., Weisdorf, D., Wagner, J. E. & Verneris, M. R., Apr 24 2018, In : Blood Advances. 2, 8, p. 909-922 14 p.

Research output: Contribution to journalArticle

Open Access
14 Scopus citations

Delineation of antigen-specific and antigen-nonspecific CD8+ memory T-cell responses after cytokine-based cancer immunotherapy

Tietze, J. K., Wilkins, D. E. C., Sckisel, G. D., Bouchlaka, M. N., Alderson, K. L., Weiss, J. M., Ames, E., Bruhn, K. W., Craft, N., Wiltrout, R. H., Longo, D. L., Lanier, L. L., Blazar, B. R., Redelman, D. & Murphy, W. J., Mar 29 2012, In : Blood. 119, 13, p. 3073-3083 11 p.

Research output: Contribution to journalArticle

41 Scopus citations

Dendritic Cell Expression of Retinal Aldehyde Dehydrogenase-2 Controls Graft-versus-Host Disease Lethality

Thangavelu, G., Lee, Y. C., Loschi, M., Melanie Schaechter, K., Feser, C. J., Koehn, B., Nowak, E. C., Zeiser, R., Serody, J. S., Murphy, W. J., Munn, D. H., Chambon, P., Noelle, R. J. & Blazar, B. R., May 1 2019, In : Journal of Immunology. 202, 9, p. 2795-2805 11 p.

Research output: Contribution to journalArticle

2 Scopus citations

Dendritic cell programming by cytomegalovirus stunts naive T cell responses via the PD-L1/PD-1 pathway

Benedict, C. A., Loewendorf, A., Garcia, Z., Blazar, B. R. & Janssen, E. M., Apr 1 2008, In : Journal of Immunology. 180, 7, p. 4836-4847 12 p.

Research output: Contribution to journalArticle

67 Scopus citations

Dendritic cells pulsed or fused with AML cellular antigen provide comparable in vivo antitumor protective responses

Weigel, B. J., Panoskaltsis-Mortari, A., Diers, M., Garcia, M., Lees, C., Krieg, A. M., Chen, W. & Blazar, B. R., Oct 1 2006, In : Experimental Hematology. 34, 10, p. 1403-1412 10 p.

Research output: Contribution to journalArticle

25 Scopus citations

Dependency on intercellular adhesion molecule recognition and local interleukin-2 provision in generation of an in vivo CD8+ T-cell immune response to murine myeloid leukemia

Boyer, M. W., Orchard, P. J., Gorden, K. B., Anderson, P. M., McIvor, R. S. & Blazar, B. R., May 1 1995, In : Blood. 85, 9, p. 2498-2506 9 p.

Research output: Contribution to journalArticle

Open Access
30 Scopus citations

Depletion of endogenous tumor-associated regulatory T cells improves the efficacy of adoptive cytotoxic T-cell immunotherapy in murine acute myeloid leukemia

Zhou, Q., Bucher, C., Munger, M. E., Highfill, S. L., Tolar, J., Munn, D. H., Levine, B. L., Riddle, M., June, C. H., Vallera, D. A., Weigel, B. J. & Blazar, B. R., Oct 29 2009, In : Blood. 114, 18, p. 3793-3802 10 p.

Research output: Contribution to journalArticle

81 Scopus citations

Despite high levels of expression in thymic epithelial cells, miR-181a1 and miR-181b1 are not required for thymic development

Stefanski, H. E., Xing, Y., Taylor, P. A., Maio, S., Henao-Meija, J., Williams, A., Flavell, R. A., Hollander, G. A. & Blazar, B. R., Jun 2018, In : PloS one. 13, 6, e0198871.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Development of a decellularized lung bioreactor system for bioengineering the lung: The matrix reloaded

Price, A. P., England, K. A., Matson, A. M., Blazar, B. R. & Panoskaltsis-Mortari, A., Aug 1 2010, In : Tissue Engineering - Part A. 16, 8, p. 2581-2591 11 p.

Research output: Contribution to journalArticle

234 Scopus citations
31 Scopus citations

Differential effects of 2-deoxy-D-glucose on in vitro expanded human regulatory T cell subsets

Tanimine, N., Germana, S. K., Fan, M., Hippen, K., Blazar, B. R., Markmann, J. F., Turka, L. A. & Priyadharshini, B., Jun 2019, In : PloS one. 14, 6, e0217761.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Differential effects of proteasome inhibition by bortezomib on murine acute graft-versus-host disease (GVHD): Delayed administration of bortezomib results in increased GVHD-dependent gastrointestinal toxicity

Sun, K., Wilkins, D. E. C., Anver, M. R., Sayers, T. J., Panoskaltsis-Mortari, A., Blazar, B. R., Welniak, L. A. & Murphy, W. J., Nov 1 2005, In : Blood. 106, 9, p. 3293-3299 7 p.

Research output: Contribution to journalArticle

108 Scopus citations

Differential effects of the absence of interferon-γ and IL-4 in acute graft-versus-host disease after allogeneic bone marrow transplantation in mice

Murphy, W. J., Welniak, L. A., Taub, D. D., Wiltrout, R. H., Taylor, P. A., Vallera, D. A., Kopf, M., Young, H., Longo, D. L. & Blazar, B. R., Nov 1 1998, In : Journal of Clinical Investigation. 102, 9, p. 1742-1748 7 p.

Research output: Contribution to journalArticle

182 Scopus citations

Differential phenotypes of memory CD4 and CD8 T cells in the spleen and peripheral tissues following immunostimulatory therapy

Sckisel, G. D., Mirsoian, A., Minnar, C. M., Crittenden, M., Curti, B., Chen, J. Q., Blazar, B. R., Borowsky, A. D., Monjazeb, A. M. & Murphy, W. J., Apr 18 2017, In : Journal for ImmunoTherapy of Cancer. 5, 1, 33.

Research output: Contribution to journalArticle

Open Access
9 Scopus citations

Differential Regulation of T-cell Immunity and Tolerance by Stromal Laminin Expressed in the Lymph Node

Simon, T., Li, L., Wagner, C., Zhang, T., Saxena, V., Brinkman, C. C., Tostanoski, L. H., Ostrand-Rosenberg, S., Jewell, C., Shea-Donohue, T., Hippen, K., Blazar, B., Abdi, R. & Bromberg, J. S., Oct 1 2019, In : Transplantation. 103, 10, p. 2075-2089 15 p.

Research output: Contribution to journalArticle

4 Scopus citations

Differential roles for CCR5 expression on donor T cells during graft-versus-host disease based on pretransplant conditioning

Wysocki, C. A., Burkett, S. B., Panoskaltsis-Mortari, A., Kirby, S. L., Luster, A. D., McKinnon, K., Blazar, B. R. & Serody, J. S., Jul 15 2004, In : Journal of Immunology. 173, 2, p. 845-854 10 p.

Research output: Contribution to journalArticle

100 Scopus citations

Difficult stem cell mobilization despite adequate CD34+ cell dose predicts shortened progression free and overall survival after autologous HSCT for lymphoma

Tomblyn, M., Burns, L. J., Blazar, B., Wagner, J., Lee, C., Rogers, T., McGlave, P., Miller, J. S. & Weisdorf, D. J., Jul 1 2007, In : Bone marrow transplantation. 40, 2, p. 111-118 8 p.

Research output: Contribution to journalArticle

28 Scopus citations

Diffusible factors from the murine cell line M2-10B4 support human in vitro hematopoiesis

Burroughs, J., Gupta, P., Blazar, B. R. & Verfaillie, C. M., Jan 1 1994, In : Experimental Hematology. 22, 11, p. 1095-1101 7 p.

Research output: Contribution to journalArticle

40 Scopus citations

Diminished neo-antigen response to keyhole limpet hemocyanin (KLH) vaccines in patients after treatment with chemotherapy or hematopoietic cell transplantation

Miller, J. S., Curtsinger, J., Berthold, M., Malvey, K., Bliss, R. L., Le, C. T., Fautsch, S. K., Dudek, A. Z., Blazar, B. R. & Panoskaltsis-Mortari, A., Nov 1 2005, In : Clinical Immunology. 117, 2, p. 144-151 8 p.

Research output: Contribution to journalArticle

19 Scopus citations

Dissecting the biology of allogeneic HSCT to enhance the GvT effect whilst minimizing GvHD

Blazar, B. R., Hill, G. R. & Murphy, W. J., Aug 1 2020, In : Nature Reviews Clinical Oncology. 17, 8, p. 475-492 18 p.

Research output: Contribution to journalReview article

1 Scopus citations

Distinct Regulation of Th17 and Th1 Cell Differentiation by Glutaminase-Dependent Metabolism

Johnson, M. O., Wolf, M. M., Madden, M. Z., Andrejeva, G., Sugiura, A., Contreras, D. C., Maseda, D., Liberti, M. V., Paz, K., Kishton, R. J., Johnson, M. E., de Cubas, A. A., Wu, P., Li, G., Zhang, Y., Newcomb, D. C., Wells, A. D., Restifo, N. P., Rathmell, W. K., Locasale, J. W. & 3 others, Davila, M. L., Blazar, B. R. & Rathmell, J. C., Dec 13 2018, In : Cell. 175, 7, p. 1780-1795.e19

Research output: Contribution to journalArticle

Open Access
67 Scopus citations

Distinct Regulatory and Effector T Cell Metabolic Demands during Graft-Versus-Host Disease

Hippen, K. L., Aguilar, E. G., Rhee, S. Y., Bolivar-Wagers, S. & Blazar, B. R., Jan 2020, In : Trends in Immunology. 41, 1, p. 77-91 15 p.

Research output: Contribution to journalReview article

Open Access

Distinct roles for donor- and host-derived antigen-presenting cells and costimulatory molecules in murine chronic graft-versus-host disease: Requirements depend on target organ

Anderson, B. E., McNiff, J. M., Jain, D., Blazar, B. R., Shlomchik, W. D. & Shlomchik, M. J., Mar 1 2005, In : Blood. 105, 5, p. 2227-2234 8 p.

Research output: Contribution to journalArticle

170 Scopus citations

DNA methylation of Runx1 regulatory regions correlates with transition from primitive to definitive hematopoietic potential in vitro and in vivo

Webber, B. R., Iacovino, M., Choi, S. H., Tolar, J., Kyba, M. & Blazar, B. R., Jan 1 2013, In : Blood. 122, 17, p. 2978-2986 9 p.

Research output: Contribution to journalArticle

13 Scopus citations

Donor and host B7-H4 expression negatively regulates acute graft-versus-host disease lethality

Saha, A., Taylor, P. A., Lees, C. J., Panoskaltsis-Mortari, A., Osborn, M. J., Feser, C. J., Thangavelu, G., Melchinger, W., Refaeli, Y., Hill, G. R., Munn, D. H., Murphy, W. J., Serody, J. S., Maillard, I., Kreymborg, K., van den Brink, M., Dong, C., Huang, S., Zang, X., Allison, J. P. & 2 others, Zeiser, R. & Blazar, B. R., 2019, In : JCI Insight. 4, 19, e127716.

Research output: Contribution to journalArticle

Open Access

Donor and host influences in bone marrow transplantation for immunodeficiency disease and leukemia

Kersey, J., Filipovich, A., McGlave, P., Woods, W., Weisdorf, D., Naglia, J., Dusenbery, K., Blazar, B., Nesbit, M., Ramsay, N., Frank, Boxer & Humbert, Jan 1 1993, In : Seminars in hematology. 30, 4 SUPPL. 4, p. 105-109 5 p.

Research output: Contribution to journalArticle

2 Scopus citations
Open Access
5 Scopus citations

Donor B-cell alloantibody deposition and germinal center formation are required for the development of murine chronic GVHD and bronchiolitis obliterans

Srinivasan, M., Flynn, R., Price, A., Ranger, A., Browning, J. L., Taylor, P. A., Ritz, J., Antin, J. H., Murphy, W. J., Luznik, L., Shlomchik, M. J., Panoskaltsis-Mortari, A. & Blazar, B. R., Feb 9 2012, In : Blood. 119, 6, p. 1570-1580 11 p.

Research output: Contribution to journalArticle

126 Scopus citations

Donor CD4+Foxp3+regulatory T cells are necessary for posttransplantation cyclophosphamide-mediated protection against GVHD in mice

Ganguly, S., Ross, D. B., Panoskaltsis-Mortari, A., Kanakry, C. G., Blazar, B. R., Levy, R. B. & Luznik, L., Sep 25 2014, In : Blood. 124, 13, p. 2131-2141 11 p.

Research output: Contribution to journalArticle

76 Scopus citations
10 Scopus citations

Donor T cells primed on leukemia lysate-pulsed recipient APCs mediate strong graft-versus-leukemia effects across MHC barriers in full chimeras

Ghosh, A., Koestner, W., Hapke, M., Schlaphoff, V., Länger, F., Baumann, R., Koenecke, C., Cornberg, M., Welte, K., Blazar, B. R. & Sauer, M. G., Nov 17 2009, In : Blood. 113, 18, p. 4440-4448 9 p.

Research output: Contribution to journalArticle

14 Scopus citations
36 Scopus citations

Dose-escalated interleukin-2 therapy for refractory chronic graft-versus-host disease in adults and children

Whangbo, J. S., Kim, H. T., Mirkovic, N., Leonard, L., Poryanda, S., Silverstein, S., Kim, S., Reynolds, C. G., Rai, S. C., Verrill, K., Lee, M. A., Margossian, S., Duncan, C., Lehmann, L., Huang, J., Nikiforow, S., Alyea, E. P., Armand, P., Cutler, C. S., Ho, V. T. & 5 others, Blazar, B. R., Antin, J. H., Soiffer, R. J., Ritz, J. & Koreth, J., Sep 10 2019, In : Blood Advances. 3, 17, p. 2550-2561 12 p.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations
1 Scopus citations
104 Scopus citations
Open Access

Early notch signals induce a pathogenic molecular signature during priming of alloantigen-specific conventional CD4+ T cells in graft-versus-host disease

Chung, J., Radojcic, V., Perkey, E., Parnell, T. J., Niknafs, Y., Jin, X., Friedman, A., Labrecque, N., Blazar, B. R., Brennan, T. V., Siebel, C. W. & Maillard, I., 2019, In : Journal of Immunology. 203, 2, p. 557-568 12 p.

Research output: Contribution to journalArticle

2 Scopus citations

Effective immunization against neuroblastoma using double-transduced tumor cells secreting GM-CSF and interferon-γ

Bausero, M. A., Panoskaltsis-Mortari, A., Blazar, B. R. & Katsanis, E., Jan 1 1996, In : Journal of Immunotherapy. 19, 2, p. 113-124 12 p.

Research output: Contribution to journalArticle

28 Scopus citations

Effective Multi-lineage Engraftment in a Mouse Model of Fanconi Anemia Using Non-genotoxic Antibody-Based Conditioning

Srikanthan, M. A., Humbert, O., Haworth, K. G., Ironside, C., Rajawat, Y. S., Blazar, B. R., Palchaudhuri, R., Boitano, A. E., Cooke, M. P., Scadden, D. T. & Kiem, H. P., Jun 12 2020, In : Molecular Therapy - Methods and Clinical Development. 17, p. 455-464 10 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Effect of IL-7 or IL-4 on reconstitution of donor lymphoid cells in congenic murine bone marrow transplantation

Mathur, A., Vallera, D. A., Taylor, P. A., Widmer, M. B., Yang, C., Prabhu, A. & Blazar, B. R., Jan 1 1995, In : Bone marrow transplantation. 16, 1, p. 119-124 6 p.

Research output: Contribution to journalArticle

6 Scopus citations

Effect of Radiation Dose-Rate on Hematopoietic Cell Engraftment in Adult Zebrafish

Glass, T. J., Hui, S. K., Blazar, B. R. & Lund, T. C., Sep 18 2013, In : PloS one. 8, 9, e73745.

Research output: Contribution to journalArticle

9 Scopus citations
Open Access
11 Scopus citations

Effect of sepsis syndrome on neonatal protein and energy metabolism

Mrozek, J. D., Georgieff, M. K., Blazar, B. R., Mammel, M. C. & Schwarzenberg, S. J., Mar 2000, In : Journal of Perinatology. 20, 2, p. 96-100 5 p.

Research output: Contribution to journalArticle

18 Scopus citations

Effect of tumor necrosis factor α and of the soluble tumor necrosis factor receptor on insulin secretion of isolated islets of Langerhans

Xenos, E. S., Farney, A. C., Widmer, M. B., Casanova, D., Stevens, R. B., Blazar, B. R., Sutherland, D. E. R. & Gores, P. F., Dec 1 1992, In : Transplantation proceedings. 24, 6, p. 2863-2864 2 p.

Research output: Contribution to journalArticle

19 Scopus citations

Effector CD4+ T cells, the cytokines they generate, and GVHD: Something old and something new

Coghill, J. M., Sarantopoulos, S., Moran, T. P., Murphy, W. J., Blazar, B. R. & Serody, J. S., Mar 24 2011, In : Blood. 117, 12, p. 3268-3276 9 p.

Research output: Contribution to journalReview article

106 Scopus citations