1982 …2020

Research output per year

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Research Output

39 Scopus citations

Circulating anticoagulant glycosaminoglycans in mucopolysaccharidosis type I

Tolar, J., Orchard, P. J., Key, N. S. & Blazar, B. R., May 1 2008, In : Journal of Thrombosis and Haemostasis. 6, 5, p. 893-895 3 p.

Research output: Contribution to journalArticle

5 Scopus citations

Circulating T follicular helper cells with increased function during chronic graft-versus-host disease

Forcade, E., Kim, H. T., Cutler, C., Wang, K., Alho, A. C., Nikiforow, S., Ho, V. T., Koreth, J., Armand, P., Alyea, E. P., Blazar, B. R., Soiffer, R. J., Antin, J. H. & Ritz, J., May 19 2016, In : Blood. 127, 20, p. 2489-2497 9 p.

Research output: Contribution to journalArticle

Open Access
37 Scopus citations
195 Scopus citations

Clinical application of expanded CD4+25+ cells

June, C. H. & Blazar, B. R., Apr 1 2006, In : Seminars in Immunology. 18, 2, p. 78-88 11 p.

Research output: Contribution to journalReview article

75 Scopus citations

Clinical perspectives for regulatory T cells in transplantation tolerance

Hippen, K. L., Riley, J. L., June, C. H. & Blazar, B. R., Dec 1 2011, In : Seminars in Immunology. 23, 6, p. 462-468 7 p.

Research output: Contribution to journalReview article

88 Scopus citations
34 Scopus citations

CMV reactivation drives posttransplant T-cell reconstitution and results in defects in the underlying TCRβ repertoire

Suessmuth, Y., Mukherjee, R., Watkins, B., Koura, D. T., Finstermeier, K., Desmarais, C., Stempora, L., Horan, J. T., Langston, A., Qayed, M., Khoury, H. J., Grizzle, A., Cheeseman, J. A., Conger, J. A., Robertson, J., Garrett, A., Kirk, A. D., Waller, E. K., Blazar, B. R., Mehta, A. K. & 2 others, Robins, H. S. & Kean, L. S., Jun 18 2015, In : Blood. 125, 25, p. 3835-3850 16 p.

Research output: Contribution to journalArticle

75 Scopus citations
Open Access
101 Scopus citations

Coexpression of Tim-3 and PD-1 identifies a CD8+ T-cell exhaustion phenotype in mice with disseminated acute myelogenous leukemia

Zhou, Q., Munger, M. E., Veenstra, R. G., Weigel, B. J., Hirashima, M., Munn, D. H., Murphy, W. J., Azuma, M., Anderson, A. C., Kuchroo, V. K. & Blazar, B. R., Apr 28 2011, In : Blood. 117, 17, p. 4501-4510 10 p.

Research output: Contribution to journalArticle

350 Scopus citations

Combination graft-versus-host disease prophylaxis using immunotoxin (anti-CD5-RTA [Xomazyme-CD5]) plus methotrexate and cyclosporine or prednisone after unrelated donor marrow transplantation

Weisdorf, D., Filipovich, A., McGlave, P., Ramsay, N., Kersey, J., Miller, W. & Blazar, B., Jan 1 1993, In : Bone marrow transplantation. 12, 5, p. 531-536 6 p.

Research output: Contribution to journalArticle

20 Scopus citations

Combination of rhIL-11 + G-CSF enhances platelet (PLT) and myeloid recovery following ifosfamide, carboplatin, and etoposdde (ICE) chemotherapy in children with solid tumors (ST): RML-11 is well tolerated at double the adult recommended dose

Goldman, S., Davenport, V., Reaman, G., Laver, J., Kreissman, S., Blazar, B., Berg, S., Kaye, J., Patterson, F. & Cairo, M. S., 1997, In : Experimental Hematology. 25, 8, 1 p.

Research output: Contribution to journalArticle

2 Scopus citations

Combination Therapy Using IL-2 and Anti-CD25 Results in Augmented Natural Killer Cell-Mediated Antitumor Responses

Hallett, W. H. D., Ames, E., Álvarez, M., Barao, I., Taylor, P. A., Blazar, B. R. & Murphy, W. J., Oct 2008, In : Biology of Blood and Marrow Transplantation. 14, 10, p. 1088-1099 12 p.

Research output: Contribution to journalArticle

33 Scopus citations

Combined effects of calcineurin inhibitors or sirolimus with anti-CD40L mAb on alloengraftment under nonmyeloablative conditions

Taylor, P. A., Lees, C. J., Wilson, J. M., Ehrhardt, M. J., Campbell, M. T., Noelle, R. J. & Blazar, B. R., Nov 1 2002, In : Blood. 100, 9, p. 3400-3407 8 p.

Research output: Contribution to journalArticle

59 Scopus citations

Combined OX40L and mTOR blockade controls effector T cell activation while preserving Treg reconstitution after transplant

Tkachev, V., Furlan, S. N., Watkins, B., Hunt, D. J., Betty Zheng, H., Panoskaltsis-Mortari, A., Betz, K., Brown, M., Schell, J. B., Zeleski, K., Yu, A., Kirby, I., Cooley, S., Miller, J. S., Blazar, B. R., Casson, D., Bland-Ward, P. & Kean, L. S., Sep 20 2017, In : Science Translational Medicine. 9, 408, eaan3085.

Research output: Contribution to journalArticle

Open Access
18 Scopus citations

Comparative analysis of murine marrow-derived dendritic cells generated by Flt3L or GM-CSF/IL-4 and matured with immune stimulatory agents on the in vivo induction of antileukemia responses

Weigel, B. J., Nath, N., Taylor, P. A., Panoskaltsis-Mortari, A., Chen, W., Krieg, A. M., Brasel, K. & Blazar, B. R., Dec 1 2002, In : Blood. 100, 12, p. 4169-4176 8 p.

Research output: Contribution to journalArticle

64 Scopus citations

Comparison of engraftment in recipients of matched sibling or unrelated donor marrow allografts

Davies, S. M., Ramsay, N. K. C., Haake, R. J., Kersey, J. H., Weisdorf, D. J., Mc Glave, P. B. & Blazar, B. R., Jan 1 1994, In : Bone marrow transplantation. 13, 1, p. 51-57 7 p.

Research output: Contribution to journalArticle

45 Scopus citations

Comparison of enzymatic activity with evidence of engraftment in patients with inborn errors of metabolism receiving allogeneic marrow transplantation

Blazar, B. R., Whitley, C. B., Desnick, R. J., Pierpont, M. E., Filipovich, A. H., Ramsay, N. K., Kersey, J. H., Orr, H. T., Yasmineh, W. G. & Tsai, M. Y., Sep 18 1986, In : Birth Defects: Original Article Series. 22, 1, p. 135-152 18 p.

Research output: Contribution to journalArticle

3 Scopus citations

Comparison of three techniques for the ex vivo elimination of T cells from human bone marrow

Blazar, B. R., Quinones, R. R., Heinitz, K. J., Sevenich, E. A. & Filipovich, A. H., May 29 1985, In : Experimental Hematology. 13, 2, p. 123-128 6 p.

Research output: Contribution to journalArticle

10 Scopus citations
217 Scopus citations

Concise review: Hitting the right spot with mesenchymal stromal cells

Tolar, J., Le Blanc, K., Keating, A. & Blazar, B. R., Aug 1 2010, In : STEM CELLS. 28, 8, p. 1446-1455 10 p.

Research output: Contribution to journalArticle

274 Scopus citations
24 Scopus citations

Constitutively active Stat5b in CD4+ T cells inhibits graft-versus-host disease lethality associated with increased regulatory T-cell potency and decreased T effector cell responses

Vogtenhuber, C., Bucher, C., Highfill, S. L., Koch, L. K., Goren, E., Panoskaltsis-Mortari, A., Taylor, P. A., Farrar, M. A. & Blazar, B. R., Jul 22 2010, In : Blood. 116, 3, p. 466-474 9 p.

Research output: Contribution to journalArticle

30 Scopus citations

Continuous treatment with IL-15 exhausts human NK cells via a metabolic defect

Felices, M., Lenvik, A. J., Mc Elmurry, R. T., Chu, S., Hinderlie, P., Bendzick, L., Geller, M. A., Tolar, J., Blazar, B. R. & Miller, J. S., Feb 8 2018, In : JCI Insight. 3, 3

Research output: Contribution to journalArticle

Open Access
34 Scopus citations

Contrasting acute graft-versus-host disease effects of Tim-3/galectin-9 pathway blockade dependent upon the presence of donor regulatory T cells

Veenstra, R. G., Taylor, P. A., Zhou, Q., Panoskaltsis-Mortari, A., Hirashima, M., Flynn, R., Liu, D., Anderson, A. C., Strom, T. B., Kuchroo, V. K. & Blazar, B. R., Jul 19 2012, In : Blood. 120, 3, p. 682-690 9 p.

Research output: Contribution to journalArticle

32 Scopus citations

Control of acute myeloid leukemia relapse - Dance between KIRs and HLA

Miller, J. S. & Blazar, B. R., Aug 30 2012, In : New England Journal of Medicine. 367, 9, p. 866-868 3 p.

Research output: Contribution to journalEditorial

7 Scopus citations

Cooking up tolerance: Has a new recipe been created?

Kean, L. S. & Blazar, B. R., Jul 2012, In : American Journal of Transplantation. 12, 7, p. 1667-1669 3 p.

Research output: Contribution to journalEditorial

2 Scopus citations

Coordinated acquisition of inhibitory and activating receptors and functional properties by developing human natural killer cells

Grzywacz, B., Kataria, N., Sikora, M., Oostendorp, R. A., Dzierzak, E. A., Blazar, B. R., Miller, J. S. & Verneris, M. R., Dec 1 2006, In : Blood. 108, 12, p. 3824-3833 10 p.

Research output: Contribution to journalArticle

104 Scopus citations

Cord blood CD4+CD25+-derived T regulatory cell lines express FoxP3 protein and manifest potent suppressor function

Godfrey, W. R., Spoden, D. J., Ge, Y. G., Baker, S. R., Liu, B., Levine, B. L., June, C. H., Blazar, B. R. & Porter, S. B., Jan 15 2005, In : Blood. 105, 2, p. 750-758 9 p.

Research output: Contribution to journalArticle

235 Scopus citations

Correction

Serafini, M., Dylla, S. J., Oki, M., Heremans, Y., Tolar, J., Jiang, Y., Buckley, S. M., Pelacho, B., Burns, T. C., Frommer, S., Rossi, D. J., Bryder, D., Panoskaltsis-Mortari, A., O’Shaughnessy, M. J., Nelson-Holte, M., Fine, G. C., Weissman, I. L., Blazar, B. R. & Verfaillie, C. M., Jul 9 2007, In : Journal of Experimental Medicine. 204, 7, 1 p.

Research output: Contribution to journalComment/debate

Correction of DNA protein kinase deficiency by spliceosome-mediated RNA trans-splicing and sleeping beauty transposon delivery

Zayed, H., Xia, L., Yerich, A., Yant, S. R., Kay, M. A., Puttaraju, M., McGarrity, G. J., Wiest, D. L., McIvor, R. S., Tolar, J. & Blazar, B. R., Jul 1 2007, In : Molecular Therapy. 15, 7, p. 1273-1279 7 p.

Research output: Contribution to journalArticle

17 Scopus citations

Correction of hemophilia as a proof of concept for treatment of monogenic diseases by fetal spleen transplantation

Aronovich, A., Tchorsh, D., Katchman, H., Eventov-Friedman, S., Shezen, E., Martinowitz, U., Blazar, B. R., Cohen, S., Tal, O. & Reisner, Y., Dec 12 2006, In : Proceedings of the National Academy of Sciences of the United States of America. 103, 50, p. 19075-19080 6 p.

Research output: Contribution to journalArticle

22 Scopus citations

Corrections: B cells drive autoimmunity in mice with CD28-deficient regulatory T cells (Journal of Immunology (2017) 199 (3972-3980) DOI: 10.4049/jimmunol.1700409)

Zhang, R., Sage, P. T., Finn, K., Huynh, A., Blazar, B. R., Marangoni, F., Mempel, T. R., Sharpe, A. H. & Turka, L. A., Apr 1 2018, In : Journal of Immunology. 200, 7, p. 2505-2506 2 p.

Research output: Contribution to journalComment/debate

Open Access

Corruption of dendritic cell antigen presentation during acute GVHD leads to regulatory T-cell failure and chronic GVHD

Leveque-El Mouttie, L., Koyama, M., Le Texier, L., Markey, K. A., Cheong, M., Kuns, R. D., Lineburg, K. E., Teal, B. E., Alexander, K. A., Clouston, A. D., Blazar, B. R., Hill, G. R. & MacDonald, K. P. A., Aug 11 2016, In : Blood. 128, 6, p. 794-804 11 p.

Research output: Contribution to journalArticle

Open Access
24 Scopus citations

CPG DNA promotes the maturation and function of human monocyte-derived dendritic cells (modc) via indirect effects

Chan, A. S. H., Pond, D. P., Panoskaltsis-Mortari, A., Wang, J., Krieg, A. M., Blazar, B. R. & Chen, W., Dec 1 2000, In : Blood. 96, 11 PART II

Research output: Contribution to journalArticle

CpG oligodeoxynucleotides potentiate the antitumor effects of chemotherapy or tumor resection in an orthotopic murine model of rhabdomyosarcoma

Weigel, B. J., Rodeberg, D. A., Krieg, A. M. & Blazar, B. R., Aug 1 2003, In : Clinical Cancer Research. 9, 8, p. 3105-3114 10 p.

Research output: Contribution to journalArticle

122 Scopus citations

Crispr/cas9-based cellular engineering for targeted gene overexpression

Osborn, M. J., Lees, C. J., McElroy, A. N., Merkel, S. C., Eide, C. R., Mathews, W., Feser, C. J., Tschann, M., McElmury, R. T., Webber, B. R., Kim, C. J., Blazar, B. R. & Tolar, J., Apr 2018, In : International journal of molecular sciences. 19, 4, 946.

Research output: Contribution to journalArticle

Open Access
7 Scopus citations
Open Access
15 Scopus citations

Critical role for CCR5 in the function of donor CD4+CD25 + regulatory T cells during acute graft-versus-host disease

Wysocki, C. A., Jiang, Q., Panoskaltsis-Mortari, A., Taylor, P. A., McKinnon, K. P., Su, L., Blazar, B. R. & Serody, J. S., Nov 2005, In : Blood. 106, 9, p. 3300-3307 8 p.

Research output: Contribution to journalArticle

193 Scopus citations

Cryopreservation timing is a critical process parameter in a thymic regulatory T-cell therapy manufacturing protocol

MacDonald, K. N., Ivison, S., Hippen, K. L., Hoeppli, R. E., Hall, M., Zheng, G., Dijke, I. E., Aklabi, M. A., Freed, D. H., Rebeyka, I., Gandhi, S., West, L. J., Piret, J. M., Blazar, B. R. & Levings, M. K., Dec 2019, In : Cytotherapy. 21, 12, p. 1216-1233 18 p.

Research output: Contribution to journalArticle

CSF-1-dependant donor-derived macrophages mediate chronic graft-versus-host disease

Alexander, K. A., Flynn, R., Lineburg, K. E., Kuns, R. D., Teal, B. E., Olver, S. D., Lor, M., Raffelt, N. C., Koyama, M., Leveque, L., Le Texier, L., Melino, M., Markey, K. A., Varelias, A., Engwerda, C., Serody, J. S., Janela, B., Ginhoux, F., Clouston, A. D., Blazar, B. R. & 2 others, Hill, G. R. & MacDonald, K. P. A., Oct 1 2014, In : Journal of Clinical Investigation. 124, 10, p. 4266-4280 15 p.

Research output: Contribution to journalArticle

76 Scopus citations

CSF findings in adrenoleukodystrophy: Correlation between measures of cytokines, IgG production, and disease severity

Phillips, J. P., Lockman, L. A., Shapiro, E. G., Blazar, B. R., Loes, D. J., Moser, H. W. & Krivit, W., Jun 1994, In : Pediatric Neurology. 10, 4, p. 289-294 6 p.

Research output: Contribution to journalArticle

16 Scopus citations

Cutting edge: Identification of autoreactive CD4+ and CD8+ T cell subsets resistant to PD-1 pathway blockade

Pauken, K. E., Nelson, C. E., Martinov, T., Spanier, J. A., Heffernan, J. R., Sahli, N. L., Quarnstrom, C. F., Osum, K. C., Schenkel, J. M., Jenkins, M. K., Blazar, B. R., Vezys, V. & Fife, B. T., Apr 15 2015, In : Journal of Immunology. 194, 8, p. 3551-3555 5 p.

Research output: Contribution to journalArticle

22 Scopus citations

Cutting edge: Sustained expansion of CD8+ T cells requires CD154 expression by Th cells in acute graft versus host disease

Buhlmann, J. E., Gonzalez, M., Ginther, B., Panoskaltsis-Mortari, A., Blazar, B. R., Greiner, D. L., Rossini, A. A., Flavell, R. & Noelle, R. J., Apr 15 1999, In : Journal of Immunology. 162, 8, p. 4373-4376 4 p.

Research output: Contribution to journalArticle

86 Scopus citations

Cutting Edge: TGF-β and Phosphatidylinositol 3-Kinase Signals Modulate Distinct Metabolism of Regulatory T Cell Subsets

Priyadharshini, B., Loschi, M., Newton, R. H., Zhang, J. W., Finn, K. K., Gerriets, V. A., Huynh, A., Rathmell, J. C., Blazar, B. R. & Turka, L. A., Oct 15 2018, In : Journal of Immunology. 201, 8, p. 2215-2219 5 p.

Research output: Contribution to journalArticle

Open Access
13 Scopus citations

Cyclophosphamide prevents systemic keratinocyte growth factor-induced up-regulation of surfactant protein A after allogeneic transplant in mice

Yang, S., Panoskaltsis-Mortari, A., Ingbar, D. H., Matalon, S., Zhu, S., Resnik, E. R., Farrell, C. L., Lacey, D. L., Blazar, B. R. & Haddad, I. Y., Jan 1 2000, In : American journal of respiratory and critical care medicine. 162, 5, p. 1884-1890 7 p.

Research output: Contribution to journalArticle

17 Scopus citations

Cytokine and cytotoxic pathways of NK cell rejection of class I-deficient bone marrow grafts: Influence of mouse colony environment

Bennett, M., Taylor, P. A., Austin, M., Baker, M. B., Schook, L. B., Rutherford, M. S., Kumar, V., Podack, E. R., Mohler, K. M., Levy, R. B. & Blazar, B. R., Jun 29 1998, In : International Immunology. 10, 6, p. 785-790 6 p.

Research output: Contribution to journalArticle

28 Scopus citations

Cytokine expression in human cutaneous chronic graft-versus-host disease

Ochs, L. A., Blazar, B. R., Roy, J., Rest, E. B. & Weisdorf, D. J., Jun 1 1996, In : Bone Marrow Transplantation. 17, 6, p. 1085-1092 8 p.

Research output: Contribution to journalArticle

57 Scopus citations

Cytokine mediators of chronic graft-versus-host disease

MacDonald, K. P. A., Blazar, B. R. & Hill, G. R., Jun 30 2017, In : Journal of Clinical Investigation. 127, 7, p. 2452-2463 12 p.

Research output: Contribution to journalReview article

Open Access
23 Scopus citations