1982 …2020

Research output per year

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Research Output

B7-H3 expression in donor T cells and host cells negatively regulates acute graft-versus-host disease lethality

Veenstra, R. G., Flynn, R., Kreymborg, K., McDonald-Hyman, C., Saha, A., Taylor, P. A., Osborn, M. J., Panoskaltsis-Mortari, A., Schmitt-Graeff, A., Lieberknect, E., Murphy, W. J., Serody, J. S., Munn, D. H., Freeman, G. J., Allison, J. P., Mak, T. W., van den Brink, M., Zeiser, R. & Blazar, B. R., Jan 1 2015, In : Blood. 125, 21, p. 3335-3346 12 p.

Research output: Contribution to journalArticle

31 Scopus citations

Base Editor Correction of COL7A1 in Recessive Dystrophic Epidermolysis Bullosa Patient-Derived Fibroblasts and iPSCs

Osborn, M. J., Newby, G. A., McElroy, A. N., Knipping, F., Nielsen, S. C., Riddle, M. J., Xia, L., Chen, W., Eide, C. R., Webber, B. R., Wandall, H. H., Dabelsteen, S., Blazar, B. R., Liu, D. R. & Tolar, J., Feb 2020, In : Journal of Investigative Dermatology. 140, 2, p. 338-347.e5

Research output: Contribution to journalArticle

4 Scopus citations

B cell induction of IL-13 expression in NK cells: Role of CD244 and SLAM-associated protein

Gao, N., Schwartzberg, P., Wilder, J. A., Blazar, B. R. & Yuan, D., Mar 1 2006, In : Journal of Immunology. 176, 5, p. 2758-2764 7 p.

Research output: Contribution to journalArticle

21 Scopus citations

B cells drive autoimmunity in mice with CD28-deficient regulatory T cells

Zhang, R., Sage, P. T., Finn, K., Huynh, A., Blazar, B. R., Marangoni, F., Mempel, T. R., Sharpe, A. H. & Turka, L. A., Dec 15 2017, In : Journal of Immunology. 199, 12, p. 3972-3980 9 p.

Research output: Contribution to journalArticle

Open Access
11 Scopus citations

B Cells in Chronic Graft-versus-Host Disease

Sarantopoulos, S., Blazar, B. R., Cutler, C. & Ritz, J., Jan 1 2015, In : Biology of Blood and Marrow Transplantation. 21, 1, p. 16-23 8 p.

Research output: Contribution to journalReview article

50 Scopus citations

B-cell targeting in chronic graft-versus-host disease

Zeiser, R., Sarantopoulos, S. & Blazar, B. R., Mar 29 2018, In : Blood. 131, 13, p. 1399-1405 7 p.

Research output: Contribution to journalArticle

Open Access
16 Scopus citations

Blockade of CD40 Ligand-CD40 Interaction Impairs CD4+ T Cell-Mediated Alloreactivity by Inhibiting Mature Donor T Cell Expansion and Function after Bone Marrow Transplantation

Blazar, B. R., Taylor, P. A., Panoskaltsis-Mortari, A., Buhlman, J., Xu, J., Flavell, R. A., Korngold, R., Noelle, R. & Vallera, D. A., Jan 1 1997, In : Journal of Immunology. 158, 1, p. 29-39 11 p.

Research output: Contribution to journalArticle

155 Scopus citations

Blockade of LIGHT/LTβ and CD40 signaling induces allospecific T cell anergy, preventing graft-versus-host disease

Tamada, K., Tamura, H., Flies, D., Fu, Y. X., Celis, E., Pease, L. R., Blazar, B. R. & Chen, L., Jan 1 2002, In : Journal of Clinical Investigation. 109, 4, p. 549-557 9 p.

Research output: Contribution to journalArticle

76 Scopus citations

Blockade of programmed death-1 engagement accelerates graft-versus-host disease lethality by an IFN-γ-dependent mechanism

Blazar, B. R., Carreno, B. M., Panoskaltsis-Mortari, A., Carter, L., Iwai, Y., Yagita, H., Nishimura, H. & Taylor, P. A., Aug 1 2003, In : Journal of Immunology. 171, 3, p. 1272-1277 6 p.

Research output: Contribution to journalArticle

Open Access
220 Scopus citations

Blockade of the CD40/CD154 pathway enhances T-cell-depleted allogeneic bone marrow engraftment under nonmyeloablative and irradiation-free conditioning therapy

Pan, Y., Luo, B., Sozen, H., Kalscheuer, H., Blazar, B. R., Sutherland, D. E. R., Hering, B. J. & Guo, Z., Jul 15 2003, In : Transplantation. 76, 1, p. 216-224 9 p.

Research output: Contribution to journalArticle

13 Scopus citations

Blocking IL-21 signaling ameliorates xenogeneic GVHD induced by human lymphocytes

Hippen, K. L., Bucher, C., Schirm, D. K., Bearl, A. M., Brender, T., Mink, K. A., Waggie, K. S., De Latour, R. P., Janin, A., Curtsinger, J. M., Dillon, S. R., Miller, J. S., Socie, G. & Blazar, B. R., Jan 12 2012, In : Blood. 119, 2, p. 619-628 10 p.

Research output: Contribution to journalArticle

55 Scopus citations

Bone marrow myeloid-derived suppressor cells (MDSCs) inhibit graft-versus-host disease (GVHD) via an arginase-1-dependent mechanism that is up-regulated by interleukin-13

Highfill, S. L., Rodriguez, P. C., Zhou, Q., Goetz, C. A., Koehn, B. H., Veenstra, R., Taylor, P. A., Panoskaltsis-Mortari, A., Serody, J. S., Munn, D. H., Tolar, J., Ochoa, A. C. & Blazar, B. R., Dec 16 2010, In : Blood. 116, 25, p. 5738-5747 10 p.

Research output: Contribution to journalArticle

282 Scopus citations

Bone Marrow Stromal and Vascular Smooth Muscle Cells Have Chemosensory Capacity via Bitter Taste Receptor Expression

Lund, T. C., Kobs, A. J., Kramer, A., Nyquist, M., Kuroki, M. T., Osborn, J., Lidke, D. S., Low-Nam, S. T., Blazar, B. R. & Tolar, J., Mar 8 2013, In : PloS one. 8, 3, e58945.

Research output: Contribution to journalArticle

33 Scopus citations

Bone marrow transplantation and approaches to avoid graft-versus-host disease (GVHD)

Blazar, B. R. & Murphy, W. J., Sep 29 2005, In : Philosophical Transactions of the Royal Society B: Biological Sciences. 360, 1461, p. 1747-1767 21 p.

Research output: Contribution to journalReview article

55 Scopus citations

Bone marrow transplantation for recessive dystrophic epidermolysis bullosa

Wagner, J. E., Ishida-Yamamoto, A., McGrath, J. A., Hordinsky, M., Keene, D. R., Riddle, M. J., Osborn, M. J., Lund, T., Dolan, M., Blazar, B. R. & Tolar, J., Aug 12 2010, In : New England Journal of Medicine. 363, 7, p. 629-639 11 p.

Research output: Contribution to journalArticle

214 Scopus citations

Bone marrow transplantation without myeloablation for sickle cell disease

Krishnamurti, L., Blazar, B. R. & Wagner, J. E., Jan 4 2001, In : New England Journal of Medicine. 344, 1, 1 p.

Research output: Contribution to journalLetter

60 Scopus citations

Bortezomib-based graft-versus-host disease prophylaxis in HLA-mismatched unrelated donor transplantation

Koreth, J., Stevenson, K. E., Kim, H. T., McDonough, S. M., Bindra, B., Armand, P., Ho, V. T., Cutler, C., Blazar, B. R., Antin, J. H., Soiffer, R. J., Ritz, J. & Alyea, E. P., Sep 10 2012, In : Journal of Clinical Oncology. 30, 26, p. 3202-3208 7 p.

Research output: Contribution to journalArticle

100 Scopus citations

Bortezomib-based immunosuppression after reduced-intensity conditioning hematopoietic stem cell transplantation: Randomized phase II results

Koreth, J., Kim, H. T., Lange, P. B., Poryanda, S. J., Reynolds, C. G., Chamling Rai, S., Armand, P., Cutler, C. S., Ho, V. T., Glotzbecker, B., Yusuf, R., Nikiforow, S., Chen, Y. B., Dey, B., McMasters, M., Ritz, J., Blazar, B. R., Soiffer, R. J., Antin, J. H. & Alyea, E. P., Feb 28 2018, In : Haematologica. 103, 3, p. 522-530 9 p.

Research output: Contribution to journalArticle

Open Access
15 Scopus citations

Brain catalase activity following syngeneic bone marrow transplantation in acatalasemic mice

Tuchman, M., Blazar, B. R. & Krivit, W., Jan 1 1986, In : Birth Defects: Original Article Series. 22, 1, p. 165-175 11 p.

Research output: Contribution to journalArticle

2 Scopus citations

Busulfan disposition in children

Grochow, L. B., Krivit, W., Whitley, C. B. & Blazar, B., 1990, In : Blood. 75, 8, p. 1723-1727 5 p.

Research output: Contribution to journalArticle

Open Access
119 Scopus citations

Busulfan pharmacokinetics do not predict relapse in acute myeloid leukemia

Baker, K. S., Bostrom, B., De For, T. E., Ramsay, N. K. C., Woods, W. G. & Blazar, B. R., Oct 16 2000, In : Bone marrow transplantation. 26, 6, p. 607-614 8 p.

Research output: Contribution to journalArticle

20 Scopus citations

Bystander activation and anti-tumor effects of CD8+ T cells following interleukin-2 based immunotherapy is independent of CD4+ T cell help

Monjazeb, A. M., Tietze, J. K., Grossenbacher, S. K., Hsiao, H. H., Zamora, A. E., Mirsoian, A., Koehn, B., Blazar, B. R., Weiss, J. M., Wiltrout, R. H., Sckisel, G. D. & Murphy, W. J., Aug 13 2014, In : PloS one. 9, 8, e102709.

Research output: Contribution to journalArticle

13 Scopus citations

C5aR1 regulates T follicular helper differentiation and chronic graft-versus-host disease bronchiolitis obliterans

Verghese, D. A., Chun, N., Paz, K., Fribourg, M., Woodruff, T. M., Flynn, R., Hu, Y., Xiong, H., Zhang, W., Yi, Z., Du, J., Blazar, B. R. & Heeger, P. S., Dec 20 2018, In : JCI Insight. 3, 24

Research output: Contribution to journalArticle

Open Access
4 Scopus citations

Cadherin 17 mutation associated with leaky severe combined immune deficiency is corrected by HSCT

Smith, A. R., Rota, I. A., Maio, S., Massaad, M. J., Lund, T. C., Notarangelo, L. D., Holländer, G. A. & Blazar, B. R., Oct 24 2017, In : Blood Advances. 1, 23, p. 2083-2087 5 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Calcitriol for Congenital Osteopetrosis

Blazar, B. R., Fallon, M. D., Teitelbaum, S. L., Ramsay, N. K. C., Brown, D. M., Key, L. L. & Anast, C. S., Jul 5 1984, In : New England Journal of Medicine. 311, 1, 1 p.

Research output: Contribution to journalLetter

9 Scopus citations

Cardiac disease in mucopolysaccharidosis type I attributed to catecholaminergic and hemodynamic deficiencies

Palpant, N. J., Bedada, F. B., Peacock, B., Blazar, B. R., Metzger, J. M. & Tolar, J., Jan 1 2011, In : American Journal of Physiology - Heart and Circulatory Physiology. 300, 1, p. H356-H365

Research output: Contribution to journalArticle

4 Scopus citations
39 Scopus citations

Caveolin-1 regulates TCR signal strength and regulatory T-cell differentiation into alloreactive T cells

Schönle, A., Hartl, F. A., Mentzel, J., Nöltner, T., Rauch, K. S., Prestipino, A., Wohlfeil, S. A., Apostolova, P., Hechinger, A. K., Melchinger, W., Fehrenbach, K., Guadamillas, M. C., Follo, M., Prinz, G., Ruess, A. K., Pfeifer, D., Del Pozo, M. A., Schmitt-Graeff, A., Duyster, J., Hippen, K. I. & 4 others, Blazar, B. R., Schachtrup, K., Minguet, S. & Zeiser, R., Apr 14 2016, In : Blood. 127, 15, p. 1930-1939 10 p.

Research output: Contribution to journalArticle

Open Access
22 Scopus citations

CC chemokine receptor 8 potentiates donor Treg survival and is critical for the prevention of murine graft-versus-host disease

Coghill, J. M., Fowler, K. A., West, M. L., Fulton, L. M., van Deventer, H., McKinnon, K. P., Vincent, B. G., Lin, K., Panoskaltsis-Mortari, A., Cook, D. N., Blazar, B. R. & Serody, J. S., Aug 1 2013, In : Blood. 122, 5, p. 825-836 12 p.

Research output: Contribution to journalArticle

29 Scopus citations

CD154 on the surface of CD4+CD25+ regulatory T cells contributes to skin transplant tolerance

Jarvinen, L. Z., Blazar, B. R., Adeyi, O. A., Strom, T. B. & Noelle, R. J., Nov 15 2003, In : Transplantation. 76, 9, p. 1375-1379 5 p.

Research output: Contribution to journalArticle

57 Scopus citations

CD16xCD33 bispecific killer cell engager (BiKE) activates NK cells against primary MDS and MDSC CD33+ targets

Gleason, M. K., Ross, J. A., Warlick, E. D., Lund, T. C., Verneris, M. R., Wiernik, A., Spellman, S., Haagenson, M. D., Lenvik, A. J., Litzow, M. R., Epling-Burnette, P. K., Blazar, B. R., Weiner, L. M., Weisdorf, D. J., Vallera, D. A. & Miller, J. S., May 8 2014, In : Blood. 123, 19, p. 3016-3026 11 p.

Research output: Contribution to journalArticle

114 Scopus citations
58 Scopus citations

CD28 blockade controls T cell activation to prevent graft-versus-host disease in primates

Watkins, B. K., Tkachev, V., Furlan, S. N., Hunt, D. J., Betz, K., Yu, A., Brown, M., Poirier, N., Zheng, H. B., Taraseviciute, A., Colonna, L., Mary, C., Blancho, G., Soulillou, J. P., Panoskaltsis-Mortari, A., Sharma, P., Garcia, A., Strobert, E., Hamby, K., Garrett, A. & 4 others, Deane, T., Blazar, B. R., Vanhove, B. & Kean, L. S., Aug 31 2018, In : Journal of Clinical Investigation. 128, 9, p. 3991-4007 17 p.

Research output: Contribution to journalArticle

Open Access
9 Scopus citations

CD28 costimulation is essential for human T regulatory expansion and function

Golovina, T. N., Mikheeva, T., Suhoski, M. M., Aqui, N. A., Tai, V. C., Shan, X., Liu, R., Balcarcel, R. R., Fisher, N., Levine, B. L., Carroll, R. G., Warner, N., Blazar, B. R., June, C. H. & Riley, J. L., Aug 15 2008, In : Journal of Immunology. 181, 4, p. 2855-2868 14 p.

Research output: Contribution to journalArticle

112 Scopus citations

CD30/CD30 ligand (CD153) interaction regulates CD4+ T cell-mediated graft-versus-host disease

Blazar, B. R., Levy, R. B., Mak, T. W., Panoskaltsis-Mortari, A., Muta, H., Jones, M., Roskos, M., Serody, J. S., Yagita, H., Podack, E. R. & Taylor, P. A., Sep 1 2004, In : Journal of Immunology. 173, 5, p. 2933-2941 9 p.

Research output: Contribution to journalArticle

61 Scopus citations
60 Scopus citations

CD4+CD25+ immune regulatory cells are required for induction of tolerance to alloantigen via costimulatory blockade

Taylor, P. A., Noelle, R. J. & Blazar, B. R., Jun 4 2001, In : Journal of Experimental Medicine. 193, 11, p. 1311-1317 7 p.

Research output: Contribution to journalArticle

465 Scopus citations

CD4+CD25+ regulatory T-cell lines from human cord blood have functional and molecular properties of T-cell anergy

Li, L., Godfrey, W. R., Porter, S. B., Ge, Y., June, C. H., Blazar, B. R. & Boussiotis, V. A., Nov 1 2005, In : Blood. 106, 9, p. 3068-3073 6 p.

Research output: Contribution to journalArticle

115 Scopus citations
82 Scopus citations

CD47 (Integrin-associated Protein) engagement of dendritic cell and macrophage counterreceptors is required to prevent the clearance of donor lymphohematopoietic cells

Blazar, B. R., Lindberg, F. P., Ingulli, E., Panoskaltsis-Mortari, A., Oldenborg, P. A., Iizuka, K., Yokoyama, W. M. & Taylor, P. A., Aug 20 2001, In : Journal of Experimental Medicine. 194, 4, p. 541-549 9 p.

Research output: Contribution to journalArticle

130 Scopus citations

CD4 T cell sphingosine 1-phosphate receptor (S1PR)1 and S1PR4 and endothelial S1PR2 regulate afferent lymphatic migration

Xiong, Y., Piao, W., Colin Brinkman, C., Li, L., Kulinski, J. M., Olivera, A., Cartier, A., Hla, T., Hippen, K. L., Blazar, B. R., Schwab, S. R. & Bromberg, J. S., Mar 15 2019, In : Science Immunology. 4, 33, eaav1263.

Research output: Contribution to journalArticle

Open Access
6 Scopus citations

CD56 dim CD57+ NKG2C+ NK cell expansion is associated with reduced leukemia relapse after reduced intensity HCT

Cichocki, F., Cooley, S., Davis, Z., DeFor, T. E., Schlums, H., Zhang, B., Brunstein, C. G., Blazar, B. R., Wagner, J., Diamond, D. J., Verneris, M. R., Bryceson, Y. T., Weisdorf, D. J. & Miller, J. S., Feb 1 2016, In : Leukemia. 30, 2, p. 456-463 8 p.

Research output: Contribution to journalArticle

Open Access
96 Scopus citations

CD8-predominant T-cell CNS infiltration accompanies GVHD in primates and is improved with immunoprophylaxis

Kaliyaperumal, S., Watkins, B., Sharma, P., Furlan, S., Ramakrishnan, S., Giver, C., Garcia, A., Courtney, C., Knight, H., Strobert, E., Elder, E., Crenshaw, T., Blazar, B. R., Waller, E. K., Westmoreland, S. & Kean, L. S., Mar 20 2014, In : Blood. 123, 12, p. 1967-1969 3 p.

Research output: Contribution to journalLetter

15 Scopus citations

Chemokine treatment rescues profound T-lineage progenitor homing defect after bone marrow transplant conditioning in mice

Zhang, S. L., Wang, X., Manna, S., Zlotoff, D. A., Bryson, J. L., Blazar, B. R. & Bhandoola, A., Jul 10 2014, In : Blood. 124, 2, p. 296-304 9 p.

Research output: Contribution to journalArticle

18 Scopus citations

Chemotherapy rescues tumor-driven aberrant CD4+ T-cell differentiation and restores an activated polyfunctional helper phenotype

Ding, Z. C., Blazar, B. R., Mellor, A. L., Munn, D. H. & Zhou, G., Mar 25 2010, In : Blood. 115, 12, p. 2397-2406 10 p.

Research output: Contribution to journalArticle

50 Scopus citations

Chimeric antigen receptor costimulation domains modulate human regulatory T cell function

Boroughs, A. C., Larson, R. C., Choi, B. D., Bouffard, A. A., Riley, L. S., Schiferle, E., Kulkarni, A. S., Cetrulo, C. L., Ting, D., Blazar, B. R., Demehri, S. & Maus, M. V., 2019, In : JCI Insight. 4, 8, e126194.

Research output: Contribution to journalArticle

Open Access
13 Scopus citations

Chimeric antigen receptor T cell–mediated neurotoxicity in nonhuman primates

Taraseviciute, A., Tkachev, V., Ponce, R., Turtle, C. J., Snyder, J. M., Liggitt, H. D., Myerson, D., Gonzalez-Cuyar, L., Baldessari, A., English, C., Yu, A., Zheng, H., Furlan, S. N., Hunt, D. J., Hoglund, V., Finney, O., Brakke, H., Blazar, B. R., Berger, C., Riddell, S. R. & 3 others, Gardner, R., Kean, L. S. & Jensen, M. C., Jun 2018, In : Cancer discovery. 8, 6, p. 750-763 14 p.

Research output: Contribution to journalArticle

Open Access
61 Scopus citations

Chloroquine inhibition of insulin degradation in a diabetic patient in vivo and in vitro

Blazar, B. R., Whitley, C. B. & Stentz, F. B., Jan 1 1982, In : Clinical Research. 30, 4, p. 779A

Research output: Contribution to journalArticle

Chronic graft-versus-host disease: Biological insights from preclinical and clinical studies

MacDonald, K. P. A., Hill, G. R. & Blazar, B. R., Jan 5 2017, In : Blood. 129, 1, p. 13-21 9 p.

Research output: Contribution to journalReview article

Open Access
85 Scopus citations

Chronic stimulation drives human NK cell dysfunction and epigenetic reprograming

Merino, A., Zhang, B., Dougherty, P., Luo, X., Wang, J., Blazar, B. R., Miller, J. S. & Cichocki, F., Sep 3 2019, In : Journal of Clinical Investigation. 129, 9, p. 3770-3785 16 p.

Research output: Contribution to journalArticle

Open Access
9 Scopus citations