1982 …2020

Research output per year

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Research Output

Role of interleukin-12 in acute graft-versus-host disease

Welniak, L. A., Blazar, B. R., Wiltrout, R. H., Anver, M. R. & Murphy, W. J., Jan 1 2001, In : Transplantation proceedings. 33, 1-2, p. 1752-1753 2 p.

Research output: Contribution to journalArticle

17 Scopus citations

Role of myeloid-derived suppressor cells in allogeneic hematopoietic cell transplantation

Koehn, B. H. & Blazar, B. R., Aug 2017, In : Journal of Leukocyte Biology. 102, 2, p. 335-341 7 p.

Research output: Contribution to journalReview article

Open Access
17 Scopus citations

Role of transgene regulation in ex vivo lentiviral correction of artemis deficiency

Multhaup, M. M., Podetz-Pedersen, K. M., Karlen, A. D., Olson, E. R., Gunther, R., Somia, N. V., Blazar, B. R., Cowan, M. J. & McIvor, R. S., Apr 1 2015, In : Human gene therapy. 26, 4, p. 232-243 12 p.

Research output: Contribution to journalArticle

5 Scopus citations

Roles of CD28, CTLA4, and inducible costimulator in acute graft-versus-host disease in mice

Li, J., Semple, K., Suh, W. K., Liu, C., Chen, F., Blazar, B. R. & Yu, X. Z., Jul 1 2011, In : Biology of Blood and Marrow Transplantation. 17, 7, p. 962-969 8 p.

Research output: Contribution to journalArticle

29 Scopus citations

Rorc restrains the potency of ST2+ regulatory T cells in ameliorating intestinal graft-versus-host disease

Yang, J., Ramadan, A., Reichenbach, D. K., Loschi, M., Zhang, J., Griesenauer, B., Liu, H., Hippen, K. L., Blazar, B. R. & Paczesny, S., Mar 7 2019, In : JCI Insight. 4, 5

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

Ruxolitinib in corticosteroid-refractory graft-versus-host disease after allogeneic stem cell transplantation: A multicenter survey

Zeiser, R., Burchert, A., Lengerke, C., Verbeek, M., Maas-Bauer, K., Metzelder, S. K., Spoerl, S., Ditschkowski, M., Ecsedi, M., Sockel, K., Ayuk, F., Ajib, S., De Fontbrune, F. S., Na, I. K., Penter, L., Holtick, U., Wolf, D., Schuler, E., Meyer, E., Apostolova, P. & 33 others, Bertz, H., Marks, R., Lübbert, M., Wäsch, R., Scheid, C., Stölzel, F., Ordemann, R., Bug, G., Kobbe, G., Negrin, R., Brune, M., Spyridonidis, A., Schmitt-Gräff, A., Van Der Velden, W., Huls, G., Mielke, S., Grigoleit, G. U., Kuball, J., Flynn, R., Ihorst, G., Du, J., Blazar, B. R., Arnold, R., Kröger, N., Passweg, J., Halter, J., Socié, G., Beelen, D., Peschel, C., Neubauer, A., Finke, J., Duyster, J. & Von Bubnoff, N., Oct 1 2015, In : Leukemia. 29, 10, p. 2062-2068 7 p.

Research output: Contribution to journalArticle

234 Scopus citations

Salmonella-mediated therapy targeting indoleamine 2, 3-dioxygenase 1 (IDO) activates innate immunity and mitigates colorectal cancer growth

Phan, T., Nguyen, V. H., D’Alincourt, M. S., Manuel, E. R., Kaltcheva, T., Tsai, W., Blazar, B. R., Diamond, D. J. & Melstrom, L. G., Apr 1 2020, In : Cancer gene therapy. 27, 3-4, p. 235-245 11 p.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

Sarcoma derived from cultured mesenchymal stem cells

Tolar, J., Nauta, A. J., Osborn, M. J., Mortari, A. P., McElmurry, R. T., Bell, S., Xia, L., Zhou, N., Riddle, M., Schroeder, T. M., Westendorf, J. J., McIvor, R. S., Hogendoorn, P. C. W., Szuhai, K., Oseth, L., Hirsch, B., Yant, S. R., Kay, M. A., Peister, A., Prockop, D. J. & 2 others, Fibbe, W. E. & Blazar, B. R., Feb 1 2007, In : STEM CELLS. 25, 2, p. 371-379 9 p.

Research output: Contribution to journalArticle

503 Scopus citations

Scaffold protein Disc large homolog 1 is required for T-cell receptor-induced activation of regulatory T-cell function

Zanin-Zhorov, A., Lin, J., Scher, J., Kumari, S., Blair, D., Hippen, K. L., Blazar, B. R., Abramson, S. B., Lafaille, J. J. & Dustin, M. L., Jan 31 2012, In : Proceedings of the National Academy of Sciences of the United States of America. 109, 5, p. 1625-1630 6 p.

Research output: Contribution to journalArticle

34 Scopus citations

Sdf1 expression reveals a source of perivascular-derived mesenchymal stem cells in zebrafish

Lund, T. C., Patrinostro, X., Kramer, A. C., Stadem, P., Ann Higgins, L., Markowski, T. W., Wroblewski, M. S., Lidke, D. S., Tolar, J. & Blazar, B. R., Jan 1 2014, In : STEM CELLS. 32, 10, p. 2767-2779 13 p.

Research output: Contribution to journalArticle

6 Scopus citations

Second infusion of bone marrow for treatment of graft failure after allogeneic bone marrow transplantation

Davies, S. M., Weisdorf, D. J., Haake, R. J., Kersey, J. H., Mc Glave, P. B., Ramsay, N. K. C. & Blazar, B. R., Jan 1 1994, In : Bone marrow transplantation. 14, 1, p. 73-77 5 p.

Research output: Contribution to journalArticle

51 Scopus citations

Selective oral ROCK2 inhibitor down-regulates IL-21 and IL-17 secretion in human T cells via STAT3-dependent mechanism

Zanin-Zhorov, A., Weiss, J. M., Nyuydzefe, M. S., Chen, W., Scher, J. U., Mo, R., Depoil, D., Rao, N., Liu, B., Wei, J., Lucas, S., Koslow, M., Roche, M., Schueller, O., Weiss, S., Poyurovsky, M. V., Tonra, J., Hippen, K. L., Dustin, M. L., Blazar, B. R. & 2 others, Liu, C. J. & Waksal, S. D., Nov 25 2014, In : Proceedings of the National Academy of Sciences of the United States of America. 111, 47, p. 16814-16819 6 p.

Research output: Contribution to journalArticle

86 Scopus citations

Sensitive and adaptable pharmacological control of CAR T cells through extracellular receptor dimerization

Leung, W. H., Gay, J., Martin, U., Garrett, T. E., Horton, H. M., Certo, M. T., Blazar, B. R., Morgan, R. A., Gregory, P. D., Jarjour, J. & Astrakhan, A., Jun 6 2019, In : JCI insight. 4, 11, e124430.

Research output: Contribution to journalArticle

Open Access
7 Scopus citations

Separation of graft-versus-host disease from graft-versus-leukemia responses by targeting CC-chemokine receptor 7 on donor T cells

Coghill, J. M., Carlson, M. J., Panoskaltsis-Mortari, A., West, M. L., Burgents, J. E., Blazar, B. R. & Serody, J. S., Jun 10 2010, In : Blood. 115, 23, p. 4914-4922 9 p.

Research output: Contribution to journalArticle

42 Scopus citations

Serum catalase as marker of graft-vs-host disease in allogeneic bone marrow transplant recipients: Pilot study

Yasmineh, W. G., Kaur, T. P., Blazar, B. R. & Theologides, A., 1995, In : Clinical chemistry. 41, 11, p. 1574-1580 7 p.

Research output: Contribution to journalArticle

42 Scopus citations

Serum miR-29a is upregulated in acute graft-versus-host disease and activates dendritic cells through TLR binding

Ranganathan, P., Ngankeu, A., Zitzer, N. C., Leoncini, P., Yu, X., Casadei, L., Challagundla, K., Reichenbach, D. K., Garman, S., Ruppert, A. S., Volinia, S., Hofstetter, J., Efebera, Y. A., Devine, S. M., Blazar, B. R., Fabbri, M. & Garzon, R., Mar 15 2017, In : Journal of Immunology. 198, 6, p. 2500-2512 13 p.

Research output: Contribution to journalArticle

Open Access
16 Scopus citations

Short-term ex vivo activation of splenocytes with anti-CD3 plus IL-2 and infusion post-BMT into mice results in in vivo expansion of effector cells with potent anti-lymphoma activity

Katsanis, E., Xu, Z., Anderson, P. M., Dancisak, B. B., Bausero, M. A., Weisdorf, D. J., Blazar, B. R. & Ochoa, A. C., Jan 1 1994, In : Bone marrow transplantation. 14, 4, p. 563-572 10 p.

Research output: Contribution to journalArticle

12 Scopus citations

Short-term inhibition of p53 combined with keratinocyte growth factor improves thymic epithelial cell recovery and enhances T-cell reconstitution after murine bone marrow transplantation

Kelly, R. M., Goren, E. M., Taylor, P. A., Mueller, S. N., Stefanski, H. E., Osborn, M. J., Scott, H. S., Komarova, E. A., Gudkov, A. V., Holländer, G. A. & Blazar, B. R., Feb 4 2010, In : Blood. 115, 5, p. 1088-1097 10 p.

Research output: Contribution to journalArticle

34 Scopus citations

Signatures of CD8+ T cell dysfunction in AML patients and their reversibility with response to chemotherapy

Knaus, H. A., Berglund, S., Hackl, H., Blackford, A. L., Zeidner, J. F., Montiel-Esparza, R., Mukhopadhyay, R., Vanura, K., Blazar, B. R., Karp, J. E., Luznik, L. & Gojo, I., Nov 2 2018, In : JCI Insight. 3, 21

Research output: Contribution to journalArticle

Open Access
27 Scopus citations
8 Scopus citations
Open Access
7 Scopus citations
17 Scopus citations

Sleeping Beauty-mediated correction of Fanconi anemia type C

Hyland, K. A., Olson, E. R., Clark, K. J., Aronovich, E. L., Hackett, P. B., Blazar, B. R., Tolar, J. & Scott Mcivor, R., Sep 1 2011, In : Journal of Gene Medicine. 13, 9, p. 462-469 8 p.

Research output: Contribution to journalArticle

20 Scopus citations

Sleeping Beauty-Mediated Transposition in Stem Cells

Wilber, A., Tolar, J., Blazar, B. R., Verfaillie, C. M., Lakshmipathy, U., Kaufman, D. S. & McIvor, R. S., Apr 17 2009, Emerging Technology Platforms for Stem Cells. John Wiley & Sons, Inc., p. 341-362 22 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Sleeping beauty transposon-mediated engineering of human primary T cells for therapy of CD19+ lymphoid malignancies

Huang, X., Guo, H., Kang, J., Choi, S., Zhou, T. C., Tammana, S., Lees, C. J., Li, Z. Z., Milone, M., Levine, B. L., Tolar, J., June, C. H., McIvor, R. S., Wagner, J. E., Blazar, B. R. & Zhou, X., Mar 2008, In : Molecular Therapy. 16, 3, p. 580-589 10 p.

Research output: Contribution to journalArticle

97 Scopus citations

Small-molecule BCL6 inhibitor effectively treats mice with nonsclerodermatous chronic graft-versus-host disease

Paz, K., Flynn, R., Du, J., Qi, J., Luznik, L., Maillard, I., MacDonald, K. P., Hill, G. R., Serody, J. S., Murphy, W. J., Sage, P. T., Sharpe, A. H., Miklos, D., Cutler, C. S., Koreth, J., Antin, J. H., Soiffer, R. J., Ritz, J., Bradner, J. E., Melnick, A. M. & 1 others, Blazar, B. R., Jan 3 2019, In : Blood. 133, 1, p. 94-99 6 p.

Research output: Contribution to journalArticle

Open Access
6 Scopus citations

Sorafenib promotes graft-versus-leukemia activity in mice and humans through IL-15 production in FLT3-ITD-mutant leukemia cells

Mathew, N. R., Baumgartner, F., Braun, L., O'Sullivan, D., Thomas, S., Waterhouse, M., Müller, T. A., Hanke, K., Taromi, S., Apostolova, P., Illert, A. L., Melchinger, W., Duquesne, S., Schmitt-Graeff, A., Osswald, L., Yan, K. L., Weber, A., Tugues, S., Spath, S., Pfeifer, D. & 110 others, Follo, M., Claus, R., Lübbert, M., Rummelt, C., Bertz, H., Wäsch, R., Haag, J., Schmidts, A., Schultheiss, M., Bettinger, D., Thimme, R., Ullrich, E., Tanriver, Y., Vuong, G. L., Arnold, R., Hemmati, P., Wolf, D., Ditschkowski, M., Jilg, C., Wilhelm, K., Leiber, C., Gerull, S., Halter, J., Lengerke, C., Pabst, T., Schroeder, T., Kobbe, G., Rösler, W., Doostkam, S., Meckel, S., Stabla, K., Metzelder, S. K., Halbach, S., Brummer, T., Hu, Z., Dengjel, J., Hackanson, B., Schmid, C., Holtick, U., Scheid, C., Spyridonidis, A., Stölzel, F., Ordemann, R., Müller, L. P., Sicre-De-Fontbrune, F., Ihorst, G., Kuball, J., Ehlert, J. E., Feger, D., Wagner, E. M., Cahn, J. Y., Schnell, J., Kuchenbauer, F., Bunjes, D., Chakraverty, R., Richardson, S., Gill, S., Kröger, N., Ayuk, F., Vago, L., Ciceri, F., Müller, A. M., Kondo, T., Teshima, T., Klaeger, S., Kuster, B., Kim, D. H., Weisdorf, D., Van Der Velden, W., Dörfel, D., Bethge, W., Hilgendorf, I., Hochhaus, A., Andrieux, G., Börries, M., Busch, H., Magenau, J., Reddy, P., Labopin, M., Antin, J. H., Henden, A. S., Hill, G. R., Kennedy, G. A., Bar, M., Sarma, A., McLornan, D., Mufti, G., Oran, B., Rezvani, K., Shah, O., Negrin, R. S., Nagler, A., Prinz, M., Burchert, A., Neubauer, A., Beelen, D., Mackensen, A., Von Bubnoff, N., Herr, W., Becher, B., Socié, G., Caligiuri, M. A., Ruggiero, E., Bonini, C., Häcker, G., Duyster, J., Finke, J., Pearce, E., Blazar, B. R. & Zeiser, R., Mar 1 2018, In : Nature Medicine. 24, 3, p. 282-291 10 p.

Research output: Contribution to journalArticle

Open Access
68 Scopus citations

Sorafenib promotes graft-versus-leukemia activity in mice and humans through IL-15 production in FLT3-ITD-mutant leukemia cells (vol 24, pg 282, 2018)

Cancer and Leukemia Group B, Apr 2018, In : Nature Medicine. 24, 4, p. 526-526

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

ST2 blockade reduces sST2-producing T cells while maintaining protective mST2-expressing T cells during graft-versus-host disease

Zhang, J., Ramadan, A. M., Griesenauer, B., Li, W., Turner, M. J., Liu, C., Kapur, R., Hanenberg, H., Blazar, B. R., Tawara, I. & Paczesny, S., Oct 7 2015, In : Science Translational Medicine. 7, 308, 308ra160.

Research output: Contribution to journalArticle

72 Scopus citations

Stable gene transfer and expression in human primary T cells by the Sleeping Beauty transposon system

Huang, X., Wilber, A. C., Bao, L., Tuong, D., Tolar, J., Orchard, P. J., Levine, B. L., June, C. H., McIvor, R. S., Blazar, B. R. & Zhou, X., Jan 15 2006, In : Blood. 107, 2, p. 483-491 9 p.

Research output: Contribution to journalArticle

87 Scopus citations

STAT3 signaling in CD4+ T cells is critical for the pathogenesis of chronic sclerodermatous graft-versus-host disease in a murine model

Radojcic, V., Pletneva, M. A., Yen, H. R., Ivcevic, S., Panoskaltsis-Mortari, A., Gilliam, A. C., Drake, C. G., Blazar, B. R. & Luznik, L., Jan 15 2010, In : Journal of Immunology. 184, 2, p. 764-774 11 p.

Research output: Contribution to journalArticle

58 Scopus citations

STAT6 and furin are successive triggers for the production of TGF-β by T cells

Li, Y., Liu, W., Guan, X., Truscott, J., Creemers, J. W., Chen, H. L., Pesu, M., Abiad, R. G. E., Karacay, B., Urban, J. F., Elliott, D. E., Kaplan, M. H., Blazar, B. R. & Nedim Ince, M., Nov 1 2018, In : Journal of Immunology. 201, 9, p. 2612-2623 12 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Stem cell gene therapy for fanconi anemia: Report from the 1st international fanconi anemia gene therapy working group meeting

Tolar, J., Adair, J. E., Antoniou, M., Bartholomae, C. C., Becker, P. S., Blazar, B. R., Bueren, J., Carroll, T., Cavazzana-Calvo, M., Clapp, D. W., Dalgleish, R., Galy, A., Gaspar, H. B., Hanenberg, H., Von Kalle, C., Kiem, H. P., Lindeman, D., Naldini, L., Navarro, S., Renella, R. & 7 others, Rio, P., Sevilla, J., Schmidt, M., Verhoeyen, E., Wagner, J. E., Williams, D. A. & Thrasher, A. J., Jul 2011, In : Molecular Therapy. 19, 7, p. 1193-1198 6 p.

Research output: Contribution to journalArticle

36 Scopus citations

STING differentially regulates experimental GVHD mediated by CD8 versus CD4 T cell subsets

Bader, C. S., Barreras, H., Lightbourn, C. O., Copsel, S. N., Wolf, D., Meng, J., Ahn, J., Komanduri, K. V., Blazar, B. R., Jin, L., Barber, G. N., Roy, S. & Levy, R. B., Jul 15 2020, In : Science Translational Medicine. 12, 552

Research output: Contribution to journalArticle

Strategies to inhibit alloantibody production in alloprimed murine recipients of hematopoietic stem cell grafts

Blazar, B. R., Flynn, R., Lee, R., Marcucci, G., Caliguiri, M. A. & Heeger, P. S., Apr 1 2015, In : American Journal of Transplantation. 15, 4, p. 931-941 11 p.

Research output: Contribution to journalArticle

3 Scopus citations
Open Access
2 Scopus citations

Striking dichotomy of PD-L1 and PD-L2 pathways in regulating alloreactive CD4+ and CD8+ T cells in vivo

Habicht, A., Kewalaramani, R., Vu, M. D., Demirci, G., Blazar, B. R., Sayegh, M. H. & Li, X. C., Dec 1 2007, In : American Journal of Transplantation. 7, 12, p. 2683-2692 10 p.

Research output: Contribution to journalArticle

39 Scopus citations

Stromal cell-derived factor-1 and hematopoietic cell homing in an adult zebrafish model of hematopoietic cell transplantation

Glass, T. J., Lund, T. C., Patrinostro, X., Tolar, J., Bowman, T. V., Zon, L. I. & Blazar, B. R., Jul 21 2011, In : Blood. 118, 3, p. 766-774 9 p.

Research output: Contribution to journalArticle

26 Scopus citations

Successful adoptive transfer and in vivo expansion of human haploidentical NK cells in patients with cancer

Miller, J. S., Soignier, Y., Panoskaltsis-Mortari, A., McNearney, S. A., Yun, G. H., Fautsch, S. K., McKenna, D., Le, C., Defor, T. E., Burns, L. J., Orchard, P. J., Blazar, B. R., Wagner, J. E., Slungaard, A., Weisdorf, D. J., Okazaki, I. J. & McGlave, P. B., Apr 15 2005, In : Blood. 105, 8, p. 3051-3057 7 p.

Research output: Contribution to journalArticle

1037 Scopus citations

Successful allogeneic cryopreserved marrow transplantation

LASKY, L. C., VAN BUREN, N., Weisdorf, D. J., FILIPOVICH, A., Mc Glave, P. B., KERSEY, J. H., Mc Cullough, J., RAMSAY, N. K. C. & Blazar, B. R., Feb 1989, In : Transfusion. 29, 2, p. 182-184 3 p.

Research output: Contribution to journalArticle

15 Scopus citations

Successful donor cell engraftment in a recipient of bone marrow from a cadaveric donor

Blazar, B. R., Lasky, L. C., Perentesis, J. P., Watson, K. V., Steinberg, S. E., Filipovich, A. H., Orr, H. T. & Ramsay, N. K., 1986, In : Blood. 67, 6, p. 1655-1660 6 p.

Research output: Contribution to journalArticle

Open Access
18 Scopus citations
30 Scopus citations

Successful use of non-myeloablative therapy in the treatment of severe hemoglobinopathies: Proof of principle

Krishnamurti, L., Blazar, B. R., Grossi, M., Abel, S., Lubin, B. E., Vichinsky, E. & Wagner, J. E., Dec 1 2000, In : Blood. 96, 11 PART II, p. 18b

Research output: Contribution to journalArticle

2 Scopus citations

Superior efficacy of tumor cell vaccines grown in physiologic oxygen

Olin, M. R., Andersen, B. M., Zellmer, D. M., Grogan, P. T., Popescu, F. E., Xiong, Z., Forster, C. L., Seiler, C., SantaCruz, K. S., Chen, W., Blazar, B. R. & Ohlfest, J. R., Oct 1 2010, In : Clinical Cancer Research. 16, 19, p. 4800-4808 9 p.

Research output: Contribution to journalArticle

22 Scopus citations

Superiority of rapamycin over tacrolimus in preserving nonhuman primate treg half-life and phenotype after adoptive transfer

Singh, K., Stempora, L., Harvey, R. D., Kirk, A. D., Larsen, C. P., Blazar, B. R. & Kean, L. S., Dec 1 2014, In : American Journal of Transplantation. 14, 12, p. 2691-2703 13 p.

Research output: Contribution to journalArticle

36 Scopus citations

Suppression of natural killer cell-mediated bone marrow cell rejection by CD4+CD25+ regulatory T cells

Barao, I., Hanash, A. M., Hallett, W., Welniak, L. A., Sun, K., Redelman, D., Blazar, B. R., Levy, R. B. & Murphy, W. J., Apr 4 2006, In : Proceedings of the National Academy of Sciences of the United States of America. 103, 14, p. 5460-5465 6 p.

Research output: Contribution to journalArticle

112 Scopus citations

Suppressor function of umbilical cord blood-derived CD4 +CD25+ T-regulatory cells exposed to graft-versus-host disease drugs

Porter, S. B., Liu, B., Rogosheske, J., Levine, B. L., June, C. H., Kohl, V. K., Wagner, J. E., Miller, J. S. & Blazar, B. R., Jul 1 2006, In : Transplantation. 82, 1, p. 23-29 7 p.

Research output: Contribution to journalArticle

18 Scopus citations

Surfactant protein A decreases lung injury and mortality after murine marrow transplantation

Yang, S., Milla, C., Panoskaltsis-Mortari, A., Hawgood, S., Blazar, B. R. & Haddad, I. Y., Sep 2002, In : American journal of respiratory cell and molecular biology. 27, 3, p. 297-305 9 p.

Research output: Contribution to journalArticle

25 Scopus citations

Surfactant protein A is a required mediator of keratinocyte growth factor after experimental marrow transplantation

Haddad, I. Y., Milla, C., Yang, S., Panoskaltsis-Mortari, A., Hawgood, S., Lacey, D. L. & Blazar, B. R., Sep 1 2003, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 285, 3 29-3, p. L602-L610

Research output: Contribution to journalArticle

13 Scopus citations