1982 …2020

Research output per year

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Research Output

Peri-alloHCT IL-33 administration expands recipient T-regulatory cells that protect mice against acute GVHD

Matta, B. M., Reichenbach, D. K., Zhang, X., Mathews, L., Koehn, B. H., Dwyer, G. K., Lott, J. M., Uhl, F. M., Pfeifer, D., Feser, C. J., Smith, M. J., Liu, Q., Zeiser, R., Blazar, B. R. & Turnquist, H. R., Jul 21 2016, In : Blood. 128, 3, p. 427-439 13 p.

Research output: Contribution to journalArticle

Open Access
51 Scopus citations
12 Scopus citations

Peyer patches are not required for acute graft-versus-host disease after myeloablative conditioning and murine allogeneic bone marrow transplantation

Welniak, L. A., Kuprash, D. V., Tumanov, A. V., Panoskaltsis-Mortari, A., Blazar, B. R., Sun, K., Nedospasov, S. A. & Murphy, W. J., Jan 1 2006, In : Blood. 107, 1, p. 410-412 3 p.

Research output: Contribution to journalArticle

33 Scopus citations

Pharmacologic inhibition of PKCa & PKCu prevents GVHD while preserving GVL activity in mice

Haarberg, K. M. K., Li, J., Heinrichs, J., Wang, D., Liu, C., Bronk, C. C., Kaosaard, K., Owyang, A. M., Holland, S., Masuda, E., Tso, K., Blazar, B. R., Anasetti, C., Beg, A. A. & Yu, X. Z., 2013, In : Blood. 122, 14, p. 2500-2511 12 p.

Research output: Contribution to journalArticle

28 Scopus citations

Phase 1/2 randomized, placebo-control trial of palifermin to prevent graft-versus-host disease (GVHD) after allogeneic hematopoietic stem cell transplantation (HSCT)

Blazar, B. R., Weisdorf, D. J., DeFor, T., Goldman, A., Braun, T., Silver, S. & Ferrara, J. L. M., Nov 1 2006, In : Blood. 108, 9, p. 3216-3222 7 p.

Research output: Contribution to journalArticle

108 Scopus citations

Phase I/II Trial of StemRegenin-1 Expanded Umbilical Cord Blood Hematopoietic Stem Cells Supports Testing as a Stand-Alone Graft

Wagner, J. E., Brunstein, C. G., Boitano, A. E., Defor, T. E., McKenna, D., Sumstad, D., Blazar, B. R., Tolar, J., Le, C., Jones, J., Cooke, M. P. & Bleul, C. C., Jan 7 2016, In : Cell Stem Cell. 18, 1, p. 144-155 12 p.

Research output: Contribution to journalArticle

Open Access
146 Scopus citations

Phase i study of alemtuzumab for therapy of steroid-refractory chronic graft-versus-host disease

Nikiforow, S., Kim, H. T., Bindra, B., McDonough, S., Glotzbecker, B., Armand, P., Koreth, J., Ho, V. T., Alyea, E. P., Blazar, B. R., Ritz, J., Soiffer, R. J., Antin, J. H. & Cutler, C. S., May 1 2013, In : Biology of Blood and Marrow Transplantation. 19, 5, p. 804-811 8 p.

Research output: Contribution to journalArticle

6 Scopus citations

Phenotypical and functional characterization of intrahepatic bile duct cells from common duct ligated mice

Hu, W., Blazar, B. R., Manivel, J. C., Paradis, K. & Sharp, H. L., Dec 1996, In : Journal of Laboratory and Clinical Medicine. 128, 6, p. 536-544 9 p.

Research output: Contribution to journalArticle

11 Scopus citations

Phosphonooxymethyl Prodrug of Triptolide: Synthesis, Physicochemical Characterization, and Efficacy in Human Colon Adenocarcinoma and Ovarian Cancer Xenografts

Patil, S., Lis, L. G., Schumacher, R. J., Norris, B. J., Morgan, M. L., Cuellar, R. A. D., Blazar, B. R., Suryanarayanan, R., Gurvich, V. J. & Georg, G. I., Dec 10 2015, In : Journal of medicinal chemistry. 58, 23, p. 9334-9344 11 p.

Research output: Contribution to journalArticle

30 Scopus citations

Physiologic control of IDO competence in splenic dendritic cells

Baban, B., Chandler, P. R., Johnson, B. A., Huang, L., Li, M., Sharpe, M. L., Francisco, L. M., Sharpe, A. H., Blazar, B. R., Munn, D. H. & Mellor, A. L., Sep 1 2011, In : Journal of Immunology. 187, 5, p. 2329-2335 7 p.

Research output: Contribution to journalArticle

59 Scopus citations

Pig embryonic pancreatic tissue as a source for transplantation in diabetes: Transient treatment with anti-LFA1, anti-CD48, and FTY720 enables long-term graft maintenance in mice with only mild ongoing immunosuppression

Tchorsh-Yutsis, D., Hecht, G., Aronovich, A., Shezen, E., Klionsky, Y., Rosen, C., Bitcover, R., Eventov-Friedman, S., Katchman, H., Cohen, S., Tal, O., Milstein, O., Yagita, H., Blazar, B. R. & Reisner, Y., Jul 2009, In : Diabetes. 58, 7, p. 1585-1594 10 p.

Research output: Contribution to journalArticle

24 Scopus citations

Pirfenidone ameliorates murine chronic GVHD through inhibition of macrophage infiltration and TGF-β production

Du, J., Paz, K., Flynn, R., Vulic, A., Robinson, T. M., Lineburg, K. E., Alexander, K. A., Meng, J., Roy, S., Panoskaltsis-Mortari, A., Loschi, M., Hill, G. R., Serody, J. S., Maillard, I., Miklos, D., Koreth, J., Cutler, C. S., Antin, J. H., Ritz, J., MacDonald, K. P. & 3 others, Schacker, T. W., Luznik, L. & Blazar, B. R., May 4 2017, In : Blood. 129, 18, p. 2570-2580 11 p.

Research output: Contribution to journalArticle

Open Access
47 Scopus citations

PKC-θ function at the immunological synapse: Prospects for therapeutic targeting

Zanin-Zhorov, A., Dustin, M. L. & Blazar, B. R., Aug 1 2011, In : Trends in Immunology. 32, 8, p. 358-363 6 p.

Research output: Contribution to journalReview article

49 Scopus citations

PKCθ is required for alloreactivity and GVHD but not for immune responses toward leukemia and infection in mice

Valenzuela, J. O., Iclozan, C., Hossain, M. S., Prlic, M., Hopewell, E., Bronk, C. C., Wang, J., Celis, E., Engelman, R. W., Blazar, B. R., Bevan, M. J., Waller, E. K., Yu, X. Z. & Beg, A. A., Dec 1 2009, In : Journal of Clinical Investigation. 119, 12, p. 3774-3786 13 p.

Research output: Contribution to journalArticle

57 Scopus citations

Plasmacytoid dendritic cells from mouse tumor-draining lymph nodes directly activate mature Tregs via indoleamine 2,3-dioxygenase

Sharma, M. D., Baban, B., Chandler, P., Hou, D. Y., Singh, N., Yagita, H., Azuma, M., Blazar, B. R., Mellor, A. L. & Munn, D. H., Sep 4 2007, In : Journal of Clinical Investigation. 117, 9, p. 2570-2582 13 p.

Research output: Contribution to journalArticle

568 Scopus citations

Plasma pharmacokinetics of high-dose oral busulfan in children and adults undergoing bone marrow transplantation

Bostrom, B., Enockson, K., Johnson, A., Bruns, A. & Blazar, B. R., Mar 24 2003, In : Pediatric transplantation. 7, SUPPL. 3, p. 12-18 7 p.

Research output: Contribution to journalArticle

30 Scopus citations

Polyamines and eIF5A Hypusination Modulate Mitochondrial Respiration and Macrophage Activation

Puleston, D. J., Buck, M. D., Klein Geltink, R. I., Kyle, R. L., Caputa, G., O'Sullivan, D., Cameron, A. M., Castoldi, A., Musa, Y., Kabat, A. M., Zhang, Y., Flachsmann, L. J., Field, C. S., Patterson, A. E., Scherer, S., Alfei, F., Baixauli, F., Austin, S. K., Kelly, B., Matsushita, M. & 17 others, Curtis, J. D., Grzes, K. M., Villa, M., Corrado, M., Sanin, D. E., Qiu, J., Pällman, N., Paz, K., Maccari, M. E., Blazar, B. R., Mittler, G., Buescher, J. M., Zehn, D., Rospert, S., Pearce, E. J., Balabanov, S. & Pearce, E. L., Aug 6 2019, In : Cell Metabolism. 30, 2, p. 352-363.e8

Research output: Contribution to journalArticle

Open Access
26 Scopus citations

Polyfunctional CD4+ T cells are essential for eradicating advanced B-cell lymphoma after chemotherapy

Ding, Z. C., Huang, L., Blazar, B. R., Yagita, H., Mellor, A. L., Munn, D. H. & Zhou, G., Sep 13 2012, In : Blood. 120, 11, p. 2229-2239 11 p.

Research output: Contribution to journalArticle

43 Scopus citations

Post-BMT lung injury occurs independently of the expression of CCL2 or its receptor, CCR2, on host cells

Panoskaltsis-Mortari, A., Hermanson, J. R., Taras, E., Wangensteen, O. D., Charo, I. F., Rollins, B. J. & Blazar, B. R., Feb 1 2004, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 286, 2 30-2, p. L284-L292

Research output: Contribution to journalArticle

10 Scopus citations

Post-Transplantation B Cell Activating Factor and B Cell Recovery before Onset of Chronic Graft-versus-Host Disease

Jacobson, C. A., Sun, L., Kim, H. T., McDonough, S. M., Reynolds, C. G., Schowalter, M., Koreth, J., Cutler, C. S., Ho, V. T., Alyea, E. P., Armand, P., Blazar, B. R., Soiffer, R. J., Antin, J. H., Ritz, J. & Sarantopoulos, S., May 2014, In : Biology of Blood and Marrow Transplantation. 20, 5, p. 668-675 8 p.

Research output: Contribution to journalArticle

24 Scopus citations

Preclinical models of acute and chronic graft-versus-host disease: How predictive are they for a successful clinical translation?

Zeiser, R. & Blazar, B. R., Jun 23 2016, In : Blood. 127, 25, p. 3117-3126 10 p.

Research output: Contribution to journalReview article

Open Access
34 Scopus citations

Preclinical Testing of Antihuman CD28 Fab′ Antibody in a Novel Nonhuman Primate Small Animal Rodent Model of Xenogenic Graft-Versus-Host Disease

Hippen, K. L., Watkins, B., Tkachev, V., Lemire, A. M., Lehnen, C., Riddle, M. J., Singh, K., Panoskaltsis-Mortari, A., Vanhove, B., Tolar, J., Kean, L. S. & Blazar, B. R., Dec 1 2016, In : Transplantation. 100, 12, p. 2630-2639 10 p.

Research output: Contribution to journalArticle

Open Access
7 Scopus citations

Predictive factors for chronic graft-versus-host disease after histocompatible sibling donor bone marrow transplantation

Ochs, L. A., Miller, W. J., Filipovich, A. H., Haake, R. J., McGlave, P. B., Blazar, B. R., Ramsay, N. K. C., Kersey, J. H. & Weisdorf, D. J., 1994, In : Bone marrow transplantation. 13, 4, p. 455-460 6 p.

Research output: Contribution to journalArticle

83 Scopus citations

Prednisone therapy for acute graft-versus-host disease: Short-versus long-term treatment: A prospective randomized trial

Hings, I. M., Filipovich, A. H., Miller, W. J., Blazar, B. L., McGlave, P. B., Ramsay, N. K. C., Kersey, J. H. & Weisdorf, D. J., Sep 1993, In : Transplantation. 56, 3, p. 577-580 4 p.

Research output: Contribution to journalArticle

70 Scopus citations

Preformed antibody, not primed T cells, is the initial and major barrier to bone marrow engraftment in allosensitized recipients

Taylor, P. A., Ehrhardt, M. J., Roforth, M. M., Swedin, J. M., Panoskaltsis-Mortari, A., Serody, J. S. & Blazar, B. R., Feb 1 2007, In : Blood. 109, 3, p. 1307-1315 9 p.

Research output: Contribution to journalArticle

81 Scopus citations
13 Scopus citations

Presumptive invasive Chrysosporium infection in a bone marrow transplant recipient

Warwick, A., Ferrieri, P., Burke, B. & Blazar, B. R., 1991, In : Bone marrow transplantation. 8, 4, p. 319-322 4 p.

Research output: Contribution to journalArticle

28 Scopus citations

Pretransplant conditioning with busulfan (myleran) and cyclophosphamide for nonmalignant diseases: Assessment of engraftment following histocompatible allogeneic bone marrow transplantation

Blazar, B. R., Ramsay, N. K. C., Kersey, J. H., Krivit, W., Arthur, D. C. & Filipovich, A. H., Jun 1985, In : Transplantation. 39, 6, p. 597-603 7 p.

Research output: Contribution to journalArticle

40 Scopus citations

Pre-transplant risk factors affecting outcome in Hurler syndrome

Orchard, P. J., Milla, C., Braunlin, E., Defor, T., Bjoraker, K., Blazar, B. R., Peters, C., Wagner, J. & Tolar, J., Jul 1 2010, In : Bone marrow transplantation. 45, 7, p. 1239-1246 8 p.

Research output: Contribution to journalArticle

22 Scopus citations
Open Access
4 Scopus citations
Open Access
21 Scopus citations

Prevention of graft-versus-host disease by adoptive T regulatory therapy is associated with active repression of peripheral blood toll-like receptor 5 mRNA expression

Sawitzki, B., Brunstein, C., Meisel, C., Schumann, J., Vogt, K., Appelt, C., Curtsinger, J. M., Verneris, M. R., Miller, J. S., Wagner, J. E. & Blazar, B. R., Feb 1 2014, In : Biology of Blood and Marrow Transplantation. 20, 2, p. 173-182 10 p.

Research output: Contribution to journalArticle

24 Scopus citations
Open Access
18 Scopus citations

Program death-1 signaling and regulatory T cells collaborate to resist the function of adoptively transferred cytotoxic T lymphocytes in advanced acute myeloid leukemia

Zhou, Q., Munger, M. E., Highfill, S. L., Tolar, J., Weigel, B. J., Riddle, M., Sharpe, A. H., Vallera, D. A., Azuma, M., Levine, B. L., June, C. H., Murphy, W. J., Munn, D. H. & Blazar, B. R., Oct 7 2010, In : Blood. 116, 14, p. 2484-2493 10 p.

Research output: Contribution to journalArticle

173 Scopus citations

Programmed death ligand-1 expression on donor T cells drives graft-versus-host disease lethality

Saha, A., O'Connor, R. S., Thangavelu, G., Lovitch, S. B., Dandamudi, D. B., Wilson, C. B., Vincent, B. G., Tkachev, V., Pawlicki, J. M., Furlan, S. N., Kean, L. S., Aoyama, K., Taylor, P. A., Panoskaltsis-Mortari, A., Foncea, R., Ranganathan, P., Devine, S. M., Burrill, J. S., Guo, L., Sacristan, C. & 15 others, Snyder, N. W., Blair, I. A., Milone, M. C., Dustin, M. L., Riley, J. L., Bernlohr, D. A., Murphy, W. J., Fife, B. T., Munn, D. H., Miller, J. S., Serody, J. S., Freeman, G. J., Sharpe, A. H., Turka, L. A. & Blazar, B. R., Jul 1 2016, In : Journal of Clinical Investigation. 126, 7, p. 2642-2660 19 p.

Research output: Contribution to journalArticle

44 Scopus citations

Programming of donor T cells using allogeneic δ-like ligand 4-positive dendritic cells to reduce GVHD in mice

Mochizuki, K., Meng, L., Mochizuki, I., Tong, Q., He, S., Liu, Y., Purushe, J., Fung, H., Zaidi, M. R., Zhang, Y., Reshef, R., Blazar, B. R., Yagita, H., Mineishi, S. & Zhang, Y., Jun 23 2016, In : Blood. 127, 25, p. 3270-3280 11 p.

Research output: Contribution to journalArticle

Open Access
11 Scopus citations
30 Scopus citations
37 Scopus citations
Open Access
15 Scopus citations

Prospective randomized trial between two doses of granulocyte colony-stimulating factor after ifosfamide, carboplatin, and etoposide in children with recurrent or refractory solid tumors: A children’s cancer group report

Cairo, M. S., Shen, V., Krailo, M. D., Bauer, M., Miser, J. S., Sato, J. K., Blatt, J., Blazar, B. R., Frierdich, S., Liu-Mares, W. & Reaman, G. H., Jan 1 2001, In : American Journal of Pediatric Hematology/Oncology. 23, 1, p. 30-38 9 p.

Research output: Contribution to journalArticle

47 Scopus citations

Protection from thymic epithelial cell injury by keratinocyte growth factor: A new approach to improve thymic and peripheral T-cell reconstitution after bone marrow transplantation

Min, D., Taylor, P. A., Panoskaltsis-Mortari, A., Chung, B., Danilenko, D. M., Farrell, C., Lacey, D. L., Blazar, B. R. & Weinberg, K. I., Jun 15 2002, In : Blood. 99, 12, p. 4592-4600 9 p.

Research output: Contribution to journalArticle

213 Scopus citations

Protein kinase C-θ mediates negative feedback on regulatory T cell function

Zanin-Zhorov, A., Ding, Y., Kumari, S., Attur, M., Hippen, K. L., Brown, M., Blazar, B. R., Abramson, S. B., Lafaille, J. J. & Dustin, M. L., Apr 16 2010, In : Science. 328, 5976, p. 372-376 5 p.

Research output: Contribution to journalArticle

206 Scopus citations

Proteomics analysis reveals a Th17-prone cell population in presymptomatic graft-versus-host disease

Li, W., Liu, L., Gomez, A., Zhang, J., Ramadan, A., Zhang, Q., Choi, S. W., Zhang, P., Greenson, J. K., Liu, C., Jiang, D., Virts, E., Kelich, S. L., Chu, H. W., Flynn, R., Blazar, B. R., Hanenberg, H., Hanash, S. & Paczesny, S., May 5 2016, In : JCI insight. 1, 6

Research output: Contribution to journalArticle

Open Access

Publisher Correction: Absence of NKG2D ligands defines leukaemia stem cells and mediates their immune evasion (Nature, (2019), 10.1038/s41586-019-1410-1)

Paczulla, A. M., Rothfelder, K., Raffel, S., Konantz, M., Steinbacher, J., Wang, H., Tandler, C., Mbarga, M., Schaefer, T., Falcone, M., Nievergall, E., Dörfel, D., Hanns, P., Passweg, J. R., Lutz, C., Schwaller, J., Zeiser, R., Blazar, B. R., Caligiuri, M. A., Dirnhofer, S. & 7 others, Lundberg, P., Kanz, L., Quintanilla-Martinez, L., Steinle, A., Trumpp, A., Salih, H. R. & Lengerke, C., Jan 1 2019, In : Nature. 572, 7770, p. E19

Research output: Contribution to journalComment/debate

Open Access

Radiotherapy in Mice with Yttrium-90-labeled Anti-Ly1 Monoclonal Antibody: Therapy of the T Cell Lymphoma EL4

Schmidberger, H., Buchsbaum, D. J., Blazar, B. R., Everson, P. & Vallera, D. A., Apr 1 1991, In : Cancer Research. 51, 7, p. 1883-1890 8 p.

Research output: Contribution to journalArticle

27 Scopus citations

Radiotherapy in Mice with Yttrium-90-labeled Anti-Ly1 Monoclonal Antibody: Therapy of Established Graft-versus-Host Disease Induced across the Major Histocompatibility Barrier

Vallera, D. A., Schmidberger, H., Buchsbaum, D. J., Everson, P., Snover, D. C. & Blazar, B. R., Apr 1 1991, In : Cancer Research. 51, 7, p. 1891-1897 7 p.

Research output: Contribution to journalArticle

7 Scopus citations
112 Scopus citations

Randomized comparison of cyclophosphamide-total body irradiation versus busulfan-cyclophosphamide conditioning in autologous bone marrow transplantation for acute myeloid leukemia

Dusenbery, K. E., Daniels, K. A., McClure, J. S., McGlaver, P. B., Ramsay, N. K. C., Blazar, B. R., Neglia, J. P., Kersey, J. H. & Woods, W. G., Jan 1 1995, In : International Journal of Radiation Oncology, Biology, Physics. 31, 1, p. 119-128 10 p.

Research output: Contribution to journalArticle

57 Scopus citations

Rapamycin, a potent inhibitor of T-cell function, prevents graft rejection in murine recipients of allogeneic T-cell-depleted donor marrow

Blazar, B. R., Taylor, P. A., Sehgal, S. N. & Vallera, D. A., 1994, In : Blood. 83, 2, p. 600-609 10 p.

Research output: Contribution to journalArticle

Open Access
36 Scopus citations