1982 …2020

Research output per year

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Research Output

2008

Transgene expression and silencing in a tick cell line: A model system for functional tick genomics

Kurtti, T. J., Mattila, J. T., Herron, M. J., Felsheim, R. F., Baldridge, G. D., Burkhardt, N. Y., Blazar, B. R., Hackett, P. B., Meyer, J. M. & Munderloh, U. G., Oct 2008, In : Insect Biochemistry and Molecular Biology. 38, 10, p. 963-968 6 p.

Research output: Contribution to journalArticle

18 Scopus citations

Transient blockade of the inducible costimulator pathway generates long-term tolerance to factor VIII after nonviral gene transfer into hemophilia A mice

Peng, B., Ye, P., Blazar, B. R., Freeman, G. J., Rawlings, D. J., Ochs, H. D. & Miao, C. H., Sep 1 2008, In : Blood. 112, 5, p. 1662-1672 11 p.

Research output: Contribution to journalArticle

47 Scopus citations

Umbilical cord blood regulatory T-cell expansion and functional effects of tumor necrosis factor receptor family members OX40 and 4-1BB expressed on artificial antigen-presenting cells

Hippen, K. L., Harker-Murray, P., Porter, S. B., Merkel, S. C., Londer, A., Taylor, D. K., Bina, M., Panoskaltsis-Mortari, A., Rubinstein, P., Van Rooijen, N., Golovina, T. N., Suhoski, M. M., Miller, J. S., Wagner, J. E., June, C. H., Riley, J. L. & Blazar, B. R., Oct 1 2008, In : Blood. 112, 7, p. 2847-2857 11 p.

Research output: Contribution to journalArticle

109 Scopus citations
33 Scopus citations
2007

A new murine model for bronchiolitis obliterans post-bone marrow transplant

Panoskaltsis-Mortari, A., Tram, K. V., Price, A. P., Wendt, C. H. & Blazar, B. R., Oct 1 2007, In : American journal of respiratory and critical care medicine. 176, 7, p. 713-723 11 p.

Research output: Contribution to journalArticle

72 Scopus citations

A novel method for KIR-ligand typing by pyrosequencing to predict NK cell alloreactivity

Yun, G., Tolar, J., Yerich, A. K., Marsh, S. G. E., Robinson, J., Noreen, H., Blazar, B. R. & Miller, J. S., Jun 2007, In : Clinical Immunology. 123, 3, p. 272-280 9 p.

Research output: Contribution to journalArticle

10 Scopus citations

A phase 2/3 multicenter randomized clinical trial of ABX-CBL versus ATG as secondary therapy for steroid-resistant acute graft-versus-host disease

MacMillan, M. L., Couriel, D., Weisdorf, D. J., Schwab, G., Havrilla, N., Fleming, T. R., Huang, S., Roskos, L., Slavin, S., Shadduck, R. K., DiPersio, J., Territo, M., Pavletic, S., Linker, C., Heslop, H. E., Deeg, H. J. & Blazar, B. R., Mar 15 2007, In : Blood. 109, 6, p. 2657-2662 6 p.

Research output: Contribution to journalArticle

64 Scopus citations

Correction

Serafini, M., Dylla, S. J., Oki, M., Heremans, Y., Tolar, J., Jiang, Y., Buckley, S. M., Pelacho, B., Burns, T. C., Frommer, S., Rossi, D. J., Bryder, D., Panoskaltsis-Mortari, A., O’Shaughnessy, M. J., Nelson-Holte, M., Fine, G. C., Weissman, I. L., Blazar, B. R. & Verfaillie, C. M., Jul 9 2007, In : Journal of Experimental Medicine. 204, 7, p. 1729 1 p.

Research output: Contribution to journalComment/debate

Correction of DNA protein kinase deficiency by spliceosome-mediated RNA trans-splicing and sleeping beauty transposon delivery

Zayed, H., Xia, L., Yerich, A., Yant, S. R., Kay, M. A., Puttaraju, M., McGarrity, G. J., Wiest, D. L., McIvor, R. S., Tolar, J. & Blazar, B. R., Jul 1 2007, In : Molecular Therapy. 15, 7, p. 1273-1279 7 p.

Research output: Contribution to journalArticle

17 Scopus citations

Difficult stem cell mobilization despite adequate CD34+ cell dose predicts shortened progression free and overall survival after autologous HSCT for lymphoma

Tomblyn, M., Burns, L. J., Blazar, B., Wagner, J., Lee, C., Rogers, T., McGlave, P., Miller, J. S. & Weisdorf, D. J., Jul 1 2007, In : Bone marrow transplantation. 40, 2, p. 111-118 8 p.

Research output: Contribution to journalArticle

28 Scopus citations

Elevation of Intracellular Cyclic AMP in Alloreactive CD4+ T Cells Induces Alloantigen-Specific Tolerance That Can Prevent GVHD Lethality In Vivo

O'Shaughnessy, M. J., Chen, Z. M., Gramaglia, I., Taylor, P. A., Panoskaltsis-Mortari, A., Vogtenhuber, C., Palmer, E., Grader-Beck, T., Boussiotis, V. A. & Blazar, B. R., May 1 2007, In : Biology of Blood and Marrow Transplantation. 13, 5, p. 530-542 13 p.

Research output: Contribution to journalArticle

17 Scopus citations

Erratum: Hematopoietic reconstitution by multipotent adult progenitor cells: Precursors to long-term hematopoietic stem cells (Journal of Experimental Medicine (January 22, 2007) 204, 1, (129-139)

Serafini, M., Dylla, S. J., Oki, M., Heremans, Y., Tolar, J., Jiang, Y., Buckley, S. M., Pelacho, B., Burns, T. C., Frommer, S., Rossi, D. J., Bryder, D., Panoskaltsis-Mortari, A., O'Shaughnessy, M. J., Nelson-Holte, M., Fine, G. C., Weissman, I. L., Blazar, B. R. & Verfaillie, C. M., Jul 9 2007, In : Journal of Experimental Medicine. 204, 7, 1 p.

Research output: Contribution to journalComment/debate

13 Scopus citations

Hematopoietic Cell Therapy for Metabolic Disease

Orchard, P. J., Blazar, B. R., Wagner, J., Charnas, L., Krivit, W. & Tolar, J., Oct 2007, In : Journal of Pediatrics. 151, 4, p. 340-346 7 p.

Research output: Contribution to journalArticle

63 Scopus citations

Hematopoietic reconstitution by multipotent adult progenitor cells: Precursors to long-term hematopoietic stem cells

Serafini, M., Dylla, S. J., Oki, M., Heremans, Y., Tolar, J., Jiang, Y., Buckley, S. M., Pelacho, B., Burns, T. C., Frommer, S., Rossi, D. J., Bryder, D., Panoskaltsis-Mortari, A., O'Shaughnessy, M. J., Nelson-Holte, M., Fine, G. C., Weissman, I. L., Blazar, B. R. & Verfaillie, C. M., Jan 22 2007, In : Journal of Experimental Medicine. 204, 1, p. 129-139 11 p.

Research output: Contribution to journalArticle

89 Scopus citations

IFN-γ mediates CD4+ T-cell loss and impairs secondary antitumor responses after successful initial immunotherapy

Berner, V., Liu, H., Zhou, Q., Alderson, K. L., Sun, K., Weiss, J. M., Back, T. C., Longo, D. L., Blazar, B. R., Wiltrout, R. H., Welniak, L. A., Redelman, D. & Murphy, W. J., Mar 2007, In : Nature Medicine. 13, 3, p. 354-360 7 p.

Research output: Contribution to journalArticle

111 Scopus citations

IL-2 receptor β-dependent STAT5 activation is required for the development of Foxp3+ regulatory T cells

Burchill, M. A., Yang, J., Vogtenhuber, C., Blazar, B. R. & Farrar, M. A., Jan 1 2007, In : Journal of Immunology. 178, 1, p. 280-290 11 p.

Research output: Contribution to journalArticle

Open Access
527 Scopus citations

Immunobiology of allogeneic hematopoietic stem cell transplantation

Welniak, L. A., Blazar, B. R. & Murphy, W. J., 2007, In : Annual Review of Immunology. 25, p. 139-170 32 p.

Research output: Contribution to journalArticle

343 Scopus citations

Insights into the mechanism of FTY720 and compatibility with regulatory T cells for the inhibition of graft-versus-host disease (GVHD)

Taylor, P. A., Ehrhardt, M. J., Lees, C. J., Tolar, J., Weigel, B. J., Panoskaltsis-Mortari, A., Serody, J. S., Brinkmann, V. & Blazar, B. R., Nov 1 2007, In : Blood. 110, 9, p. 3480-3488 9 p.

Research output: Contribution to journalArticle

60 Scopus citations

Keratinocyte growth factor (KGF) enhances postnatal T-cell development via enhancements in proliferation and function of thymic epithelial cells

Rossi, S. W., Jeker, L. T., Ueno, T., Kuse, S., Keller, M. P., Zuklys, S., Gudkov, A. V., Takahama, Y., Krenger, W., Blazar, B. R. & Holländer, G. A., May 1 2007, In : Blood. 109, 9, p. 3803-3811 9 p.

Research output: Contribution to journalArticle

133 Scopus citations

Keratinocyte growth factor augments immune reconstitution after autologous hematopoietic progenitor cell transplantation in rhesus macaques

Seggewiss, R., Loré, K., Guenaga, F. J., Pittaluga, S., Mattapallil, J., Chow, C. K., Koup, R. A., Camphausen, K., Nason, M. C., Meier-Schellersheim, M., Donahue, R. E., Blazar, B. R., Dunbar, C. E. & Douek, D. C., Jul 1 2007, In : Blood. 110, 1, p. 441-449 9 p.

Research output: Contribution to journalArticle

81 Scopus citations

Lymphodepletion followed by donor lymphocyte infusion (DLI) causes significantly more acute graft-versus-host disease than DLI alone

Miller, J. S., Weisdorf, D. J., Burns, L. J., Slungaard, A., Wagner, J. E., Verneris, M. R., Cooley, S., Wangen, R., Fautsch, S. K., Nicklow, R., DeFor, T. & Blazar, B. R., Oct 1 2007, In : Blood. 110, 7, p. 2761-2763 3 p.

Research output: Contribution to journalArticle

68 Scopus citations

PDL1 is required for peripheral transplantation tolerance and protection from chronic allograft rejection

Tanaka, K., Albin, M. J., Yuan, X., Yamaura, K., Habicht, A., Murayama, T., Grimm, M., Waaga, A. M., Ueno, T., Padera, R. F., Yagita, H., Azuma, M., Shin, T., Blazar, B. R., Rothstein, D. M., Sayegh, M. H. & Najafian, N., Oct 15 2007, In : Journal of Immunology. 179, 8, p. 5204-5210 7 p.

Research output: Contribution to journalArticle

111 Scopus citations

Plasmacytoid dendritic cells from mouse tumor-draining lymph nodes directly activate mature Tregs via indoleamine 2,3-dioxygenase

Sharma, M. D., Baban, B., Chandler, P., Hou, D. Y., Singh, N., Yagita, H., Azuma, M., Blazar, B. R., Mellor, A. L. & Munn, D. H., Sep 4 2007, In : Journal of Clinical Investigation. 117, 9, p. 2570-2582 13 p.

Research output: Contribution to journalArticle

568 Scopus citations

Preformed antibody, not primed T cells, is the initial and major barrier to bone marrow engraftment in allosensitized recipients

Taylor, P. A., Ehrhardt, M. J., Roforth, M. M., Swedin, J. M., Panoskaltsis-Mortari, A., Serody, J. S. & Blazar, B. R., Feb 1 2007, In : Blood. 109, 3, p. 1307-1315 9 p.

Research output: Contribution to journalArticle

81 Scopus citations
44 Scopus citations

Sarcoma derived from cultured mesenchymal stem cells

Tolar, J., Nauta, A. J., Osborn, M. J., Mortari, A. P., McElmurry, R. T., Bell, S., Xia, L., Zhou, N., Riddle, M., Schroeder, T. M., Westendorf, J. J., McIvor, R. S., Hogendoorn, P. C. W., Szuhai, K., Oseth, L., Hirsch, B., Yant, S. R., Kay, M. A., Peister, A., Prockop, D. J. & 2 others, Fibbe, W. E. & Blazar, B. R., Feb 2007, In : STEM CELLS. 25, 2, p. 371-379 9 p.

Research output: Contribution to journalArticle

503 Scopus citations

Striking dichotomy of PD-L1 and PD-L2 pathways in regulating alloreactive CD4+ and CD8+ T cells in vivo

Habicht, A., Kewalaramani, R., Vu, M. D., Demirci, G., Blazar, B. R., Sayegh, M. H. & Li, X. C., Dec 2007, In : American Journal of Transplantation. 7, 12, p. 2683-2692 10 p.

Research output: Contribution to journalArticle

39 Scopus citations

Sustained thymopoiesis and improvement in functional immunity induced by exogenous KGF administration in murine models of aging

Min, D., Panoskaltsis-Mortari, A., Kuro-o, M., Holländer, G. A., Blazar, B. R. & Weinberg, K. I., Mar 15 2007, In : Blood. 109, 6, p. 2529-2537 9 p.

Research output: Contribution to journalArticle

148 Scopus citations

The host immune response is essential for the beneficial effect of adult stem cells after myocardial ischemia

Tolar, J., Wang, X., Braunlin, E., McElmurry, R. T., Nakamura, Y., Bell, S., Xia, L., Zhang, J., Hu, Q., Panoskaltsis-Mortari, A., Zhang, J. & Blazar, B. R., Apr 1 2007, In : Experimental Hematology. 35, 4, p. 682-690 9 p.

Research output: Contribution to journalArticle

14 Scopus citations

The unexpected effect of cyclosporin A on CD56+CD16- and CD56+CD16+ natural killer cell subpopulations

Wang, H., Grzywacz, B., Sukovich, D., McCullar, V., Cao, Q., Lee, A. B., Blazar, B. R., Cornfield, D. N., Miller, J. S. & Verneris, M. R., Sep 1 2007, In : Blood. 110, 5, p. 1530-1539 10 p.

Research output: Contribution to journalArticle

109 Scopus citations
416 Scopus citations
2006

Adeno-associated virus-mediated delivery of a mutant endostatin in combination with carboplatin treatment inhibits orthotopic growth of ovarian cancer and improves long-term survival

Subramanian, I. V., Nguyen, T. M. B., Truskinovsky, A. M., Tolar, J., Blazar, B. R. & Ramakrishnan, S., Apr 15 2006, In : Cancer Research. 66, 8, p. 4319-4328 10 p.

Research output: Contribution to journalArticle

37 Scopus citations

B cell induction of IL-13 expression in NK cells: Role of CD244 and SLAM-associated protein

Gao, N., Schwartzberg, P., Wilder, J. A., Blazar, B. R. & Yuan, D., Mar 1 2006, In : Journal of Immunology. 176, 5, p. 2758-2764 7 p.

Research output: Contribution to journalArticle

21 Scopus citations
39 Scopus citations

Clinical application of expanded CD4+25+ cells

June, C. H. & Blazar, B. R., Apr 1 2006, In : Seminars in Immunology. 18, 2, p. 78-88 11 p.

Research output: Contribution to journalReview article

75 Scopus citations

Coordinated acquisition of inhibitory and activating receptors and functional properties by developing human natural killer cells

Grzywacz, B., Kataria, N., Sikora, M., Oostendorp, R. A., Dzierzak, E. A., Blazar, B. R., Miller, J. S. & Verneris, M. R., Dec 1 2006, In : Blood. 108, 12, p. 3824-3833 10 p.

Research output: Contribution to journalArticle

105 Scopus citations

Correction of hemophilia as a proof of concept for treatment of monogenic diseases by fetal spleen transplantation

Aronovich, A., Tchorsh, D., Katchman, H., Eventov-Friedman, S., Shezen, E., Martinowitz, U., Blazar, B. R., Cohen, S., Tal, O. & Reisner, Y., Dec 12 2006, In : Proceedings of the National Academy of Sciences of the United States of America. 103, 50, p. 19075-19080 6 p.

Research output: Contribution to journalArticle

22 Scopus citations

Dendritic cells pulsed or fused with AML cellular antigen provide comparable in vivo antitumor protective responses

Weigel, B. J., Panoskaltsis-Mortari, A., Diers, M., Garcia, M., Lees, C., Krieg, A. M., Chen, W. & Blazar, B. R., Oct 1 2006, In : Experimental Hematology. 34, 10, p. 1403-1412 10 p.

Research output: Contribution to journalArticle

25 Scopus citations

Embryonic pig pancreatic tissue transplantation for the treatment of diabetes

Eventov-Friedman, S., Tchorsh, D., Katchman, H., Shezen, E., Aronovich, A., Hecht, G., Dekel, B., Rechavi, G., Blazar, B. R., Feine, I., Tal, O., Freud, E. & Reisner, Y., 2006, In : PLoS Medicine. 3, 7, p. 1165-1177 13 p.

Research output: Contribution to journalArticle

47 Scopus citations

Host factors that impact the biodistribution and persistence of multipotent adult progenitor cells

Tolar, J., O'Shaughnessy, M. J., Panoskaltsis-Mortari, A., McElmurry, R. T., Bell, S., Riddle, M., McIvor, R. S., Yant, S. R., Kay, M. A., Krause, D., Verfaillie, C. M. & Blazar, B. R., May 15 2006, In : Blood. 107, 10, p. 4182-4188 7 p.

Research output: Contribution to journalArticle

65 Scopus citations

Inflammatory cytokines and the development of pulmonary complications after allogeneic hematopoietic cell transplantation in patients with inherited metabolic storage disorders

Kharbanda, S., Panoskaltsis-Mortari, A., Haddad, I. Y., Blazar, B. R., Orchard, P. J., Cornfield, D. N., Grewal, S. S., Peters, C., Regelmann, W. E., Milla, C. E. & Baker, K. S., Apr 1 2006, In : Biology of Blood and Marrow Transplantation. 12, 4, p. 430-437 8 p.

Research output: Contribution to journalArticle

19 Scopus citations
14 Scopus citations

Microbial translocation is a cause of systemic immune activation in chronic HIV infection

Brenchley, J. M., Price, D. A., Schacker, T. W., Asher, T. E., Silvestri, G., Rao, S., Kazzaz, Z., Bornstein, E., Lambotte, O., Altmann, D., Blazar, B. R., Rodriguez, B., Teixeira-Johnson, L., Landay, A., Martin, J. N., Hecht, F. M., Picker, L. J., Lederman, M. M., Deeks, S. G. & Douek, D. C., Dec 1 2006, In : Nature Medicine. 12, 12, p. 1365-1371 7 p.

Research output: Contribution to journalArticle

2323 Scopus citations

Overcoming T cell-mediated rejection of bone marrow allografts by T-regulatory cells: Synergism with veto cells and rapamycin

Steiner, D., Brunicki, N., Bachar-Lustig, E., Taylor, P. A., Blazar, B. R. & Reisner, Y., Jun 1 2006, In : Experimental Hematology. 34, 6, p. 802-808 7 p.

Research output: Contribution to journalArticle

26 Scopus citations

Palifermin reduces patient-reported mouth and throat soreness and improves patient functioning in the hematopoietic stem-cell transplantation setting

Stiff, P. J., Emmanouilides, C., Bensinger, W. I., Gentile, T., Blazar, B., Shea, T. C., Lu, J., Isitt, J., Cesano, A. & Spielberger, R., Nov 20 2006, In : Journal of Clinical Oncology. 24, 33, p. 5186-5193 8 p.

Research output: Contribution to journalArticle

120 Scopus citations

Peyer patches are not required for acute graft-versus-host disease after myeloablative conditioning and murine allogeneic bone marrow transplantation

Welniak, L. A., Kuprash, D. V., Tumanov, A. V., Panoskaltsis-Mortari, A., Blazar, B. R., Sun, K., Nedospasov, S. A. & Murphy, W. J., Jan 1 2006, In : Blood. 107, 1, p. 410-412 3 p.

Research output: Contribution to journalArticle

33 Scopus citations

Phase 1/2 randomized, placebo-control trial of palifermin to prevent graft-versus-host disease (GVHD) after allogeneic hematopoietic stem cell transplantation (HSCT)

Blazar, B. R., Weisdorf, D. J., DeFor, T., Goldman, A., Braun, T., Silver, S. & Ferrara, J. L. M., Nov 1 2006, In : Blood. 108, 9, p. 3216-3222 7 p.

Research output: Contribution to journalArticle

108 Scopus citations

Stable gene transfer and expression in human primary T cells by the Sleeping Beauty transposon system

Huang, X., Wilber, A. C., Bao, L., Tuong, D., Tolar, J., Orchard, P. J., Levine, B. L., June, C. H., McIvor, R. S., Blazar, B. R. & Zhou, X., Jan 15 2006, In : Blood. 107, 2, p. 483-491 9 p.

Research output: Contribution to journalArticle

87 Scopus citations

Suppression of natural killer cell-mediated bone marrow cell rejection by CD4+CD25+ regulatory T cells

Barao, I., Hanash, A. M., Hallett, W., Welniak, L. A., Sun, K., Redelman, D., Blazar, B. R., Levy, R. B. & Murphy, W. J., Apr 4 2006, In : Proceedings of the National Academy of Sciences of the United States of America. 103, 14, p. 5460-5465 6 p.

Research output: Contribution to journalArticle

112 Scopus citations