1982 …2020

Research output per year

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Research Output

2006

Suppression of natural killer cell-mediated bone marrow cell rejection by CD4+CD25+ regulatory T cells

Barao, I., Hanash, A. M., Hallett, W., Welniak, L. A., Sun, K., Redelman, D., Blazar, B. R., Levy, R. B. & Murphy, W. J., Apr 4 2006, In : Proceedings of the National Academy of Sciences of the United States of America. 103, 14, p. 5460-5465 6 p.

Research output: Contribution to journalArticle

112 Scopus citations

Suppressor function of umbilical cord blood-derived CD4 +CD25+ T-regulatory cells exposed to graft-versus-host disease drugs

Porter, S. B., Liu, B., Rogosheske, J., Levine, B. L., June, C. H., Kohl, V. K., Wagner, J. E., Miller, J. S. & Blazar, B. R., Jul 2006, In : Transplantation. 82, 1, p. 23-29 7 p.

Research output: Contribution to journalArticle

18 Scopus citations

Tolerance induction by third-party "off-the-shelf" CD4 +CD25+ Treg cells

Steiner, D., Brunicki, N., Blazar, B. R., Bachar-Lustig, E. & Reisner, Y., Jan 1 2006, In : Experimental Hematology. 34, 1, p. 66-71 6 p.

Research output: Contribution to journalArticle

38 Scopus citations

Trans-presentation of donor-derived interleukin 15 is necessary for the rapid onset of acute graft-versus-host disease but not for graft-versus-tumor activity

Blaser, B. W., Schwind, N. R., Karol, S., Chang, D., Shin, S., Roychowdhury, S., Becknell, B., Ferketich, A. K., Kusewitt, D. F., Blazar, B. R. & Caligiuri, M. A., Oct 1 2006, In : Blood. 108, 7, p. 2463-2469 7 p.

Research output: Contribution to journalArticle

23 Scopus citations
2005

Absence of host tumor necrosis factor receptor 1 attenuates manifestations of idiopathic pneumonia syndrome

Shukla, M., Yang, S., Milla, C., Panoskaltsis-Mortari, A., Blazar, B. R. & Haddad, I. Y., May 2005, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 288, 5 32-5, p. L942-L949

Research output: Contribution to journalArticle

19 Scopus citations

Activation of thymic regeneration in mice and humans following androgen blockade

Sutherland, J. S., Goldberg, G. L., Hammett, M. V., Uldrich, A. P., Berzins, S. P., Heng, T. S., Blazar, B. R., Millar, J. L., Malin, M. A., Chidgey, A. P. & Boyd, R. L., Aug 15 2005, In : Journal of Immunology. 175, 4, p. 2741-2753 13 p.

Research output: Contribution to journalArticle

320 Scopus citations

Alpha phenyl-tert-butyl nitrone (PBN) protects syngeneic marrow transplant recipients from the lethal cytokine syndrome occurring after agonistic CD40 antibody administration

Gendelman, M., Halligan, N., Komorowski, R., Logan, B., Murphy, W. J., Blazar, B. R., Pritchard, K. A. & Drobyski, W. R., Jan 1 2005, In : Blood. 105, 1, p. 428-431 4 p.

Research output: Contribution to journalArticle

9 Scopus citations

Analysis of the underlying cellular mechanisms of anti-CD154-induced graft tolerance: The interplay of clonal anergy and immune regulation

Quezada, S. A., Bennett, K., Blazar, B. R., Rudensky, A. Y., Sakaguchi, S. & Noelle, R. J., Jul 15 2005, In : Journal of Immunology. 175, 2, p. 771-779 9 p.

Research output: Contribution to journalArticle

71 Scopus citations
53 Scopus citations

Bone marrow transplantation and approaches to avoid graft-versus-host disease (GVHD)

Blazar, B. R. & Murphy, W. J., Sep 29 2005, In : Philosophical Transactions of the Royal Society B: Biological Sciences. 360, 1461, p. 1747-1767 21 p.

Research output: Contribution to journalReview article

56 Scopus citations

CD4+CD25+ regulatory T-cell lines from human cord blood have functional and molecular properties of T-cell anergy

Li, L., Godfrey, W. R., Porter, S. B., Ge, Y., June, C. H., Blazar, B. R. & Boussiotis, V. A., Nov 2005, In : Blood. 106, 9, p. 3068-3073 6 p.

Research output: Contribution to journalArticle

115 Scopus citations

Cord blood CD4+CD25+-derived T regulatory cell lines express FoxP3 protein and manifest potent suppressor function

Godfrey, W. R., Spoden, D. J., Ge, Y. G., Baker, S. R., Liu, B., Levine, B. L., June, C. H., Blazar, B. R. & Porter, S. B., Jan 15 2005, In : Blood. 105, 2, p. 750-758 9 p.

Research output: Contribution to journalArticle

235 Scopus citations

Critical role for CCR5 in the function of donor CD4+CD25 + regulatory T cells during acute graft-versus-host disease

Wysocki, C. A., Jiang, Q., Panoskaltsis-Mortari, A., Taylor, P. A., McKinnon, K. P., Su, L., Blazar, B. R. & Serody, J. S., Nov 2005, In : Blood. 106, 9, p. 3300-3307 8 p.

Research output: Contribution to journalArticle

195 Scopus citations

Differential effects of proteasome inhibition by bortezomib on murine acute graft-versus-host disease (GVHD): Delayed administration of bortezomib results in increased GVHD-dependent gastrointestinal toxicity

Sun, K., Wilkins, D. E. C., Anver, M. R., Sayers, T. J., Panoskaltsis-Mortari, A., Blazar, B. R., Welniak, L. A. & Murphy, W. J., Nov 2005, In : Blood. 106, 9, p. 3293-3299 7 p.

Research output: Contribution to journalArticle

109 Scopus citations

Diminished neo-antigen response to keyhole limpet hemocyanin (KLH) vaccines in patients after treatment with chemotherapy or hematopoietic cell transplantation

Miller, J. S., Curtsinger, J., Berthold, M., Malvey, K., Bliss, R. L., Le, C. T., Fautsch, S. K., Dudek, A. Z., Blazar, B. R. & Panoskaltsis-Mortari, A., Nov 1 2005, In : Clinical Immunology. 117, 2, p. 144-151 8 p.

Research output: Contribution to journalArticle

19 Scopus citations

Distinct roles for donor- and host-derived antigen-presenting cells and costimulatory molecules in murine chronic graft-versus-host disease: Requirements depend on target organ

Anderson, B. E., McNiff, J. M., Jain, D., Blazar, B. R., Shlomchik, W. D. & Shlomchik, M. J., Mar 1 2005, In : Blood. 105, 5, p. 2227-2234 8 p.

Research output: Contribution to journalArticle

172 Scopus citations
26 Scopus citations
31 Scopus citations

Leukocyte migration and graft-versus-host disease

Wysocki, C. A., Panoskaltsis-Mortari, A., Blazar, B. R. & Serody, J. S., Jun 1 2005, In : Blood. 105, 11, p. 4191-4199 9 p.

Research output: Contribution to journalReview article

224 Scopus citations

Natural history of pulmonary complications in children after bone marrow transplantation

Eikenberry, M., Bartakova, H., Defor, T., Haddad, I. Y., Ramsay, N. K. C., Blazar, B. R., Milla, C. E. & Cornfield, D. N., Jan 1 2005, In : Biology of Blood and Marrow Transplantation. 11, 1, p. 56-64 9 p.

Research output: Contribution to journalArticle

55 Scopus citations

Outcome of CNS and pulmonary enteroviral infections after hematopoietic cell transplantation [2]

Tan, P. L., Verneris, M. R., Charnas, L. R., Reck, S. J., Van Burik, J. A. H. & Blazar, B. R., Jul 1 2005, In : Pediatric Blood and Cancer. 45, 1, p. 74-75 2 p.

Research output: Contribution to journalLetter

8 Scopus citations

Real-time in vivo imaging of stem cells following transgenesis by transposition

Tolar, J., Osborn, M., Bell, S., McElmurry, R., Xia, L., Riddle, M., Panoskaltsis-Mortari, A., Jiang, Y., McIvor, R. S., Contag, C. H., Yant, S. R., Kay, M. A., Verfaillie, C. M. & Blazar, B. R., Jul 1 2005, In : Molecular Therapy. 12, 1, p. 42-48 7 p.

Research output: Contribution to journalArticle

32 Scopus citations

Receptors and counterreceptors involved in NK-B cell interactions

Gao, N., Dang, T., Dunnick, W. A., Collins, J. T., Blazar, B. R. & Yuan, D., Apr 1 2005, In : Journal of Immunology. 174, 7, p. 4113-4119 7 p.

Research output: Contribution to journalArticle

27 Scopus citations

Regulatory T cells

Blazar, B. R. & Taylor, P. A., Feb 1 2005, In : Biology of Blood and Marrow Transplantation. 11, 2 SUPPL. 2, p. 46-49 4 p.

Research output: Contribution to journalArticle

26 Scopus citations

Successful adoptive transfer and in vivo expansion of human haploidentical NK cells in patients with cancer

Miller, J. S., Soignier, Y., Panoskaltsis-Mortari, A., McNearney, S. A., Yun, G. H., Fautsch, S. K., McKenna, D., Le, C., Defor, T. E., Burns, L. J., Orchard, P. J., Blazar, B. R., Wagner, J. E., Slungaard, A., Weisdorf, D. J., Okazaki, I. J. & McGlave, P. B., Apr 15 2005, In : Blood. 105, 8, p. 3051-3057 7 p.

Research output: Contribution to journalArticle

1043 Scopus citations

Targeting of inducible costimulator (ICOS) expressed on alloreactive T cells down-regulates graft-versus-host disease (GVHD) and facilitates engraftment of allogeneic bone marrow (BM)

Taylor, P. A., Panoskaltsis-Mortari, A., Freeman, G. J., Sharpe, A. H., Noelle, R. J., Rudensky, A. Y., Mak, T. W., Serody, J. S. & Blazar, B. R., Apr 15 2005, In : Blood. 105, 8, p. 3372-3380 9 p.

Research output: Contribution to journalArticle

88 Scopus citations

The E. Donnall Thomas lecture: Manipulating and visualizing T-cell alloresponses

Blazar, B. R., Sep 2005, In : Biology of Blood and Marrow Transplantation. 11, 9, p. 651-656 6 p.

Research output: Contribution to journalReview article

1 Scopus citations

Transplantation of 2 partially HLA-matched umbilical cord blood units to enhance engraftment in adults with hematologic malignancy

Barker, J. N., Weisdorf, D. J., DeFor, T. E., Blazar, B. R., McGlave, P. B., Miller, J. S., Verfaillie, C. M. & Wagner, J. E., Feb 1 2005, In : Blood. 105, 3, p. 1343-1347 5 p.

Research output: Contribution to journalArticle

698 Scopus citations

Tumor-induced mechanical hyperalgesia involves CGRP receptors and altered innervation and vascularization of DsRed2 fluorescent hindpaw tumors

Wacnik, P. W., Baker, C. M., Herron, M. J., Kren, B. T., Blazar, B. R., Wilcox, G. L., Hordinsky, M. K., Beitz, A. J. & Ericson, M. E., May 2005, In : Pain. 115, 1-2, p. 95-106 12 p.

Research output: Contribution to journalArticle

40 Scopus citations
2004

An absence of CCR5 on donor cells results in acceleration of acute graft-vs-host disease

Welniak, L. A., Wang, Z., Sun, K., Kuziel, W., Anver, M. R., Blazar, B. R. & Murphy, W. J., Mar 2004, In : Experimental Hematology. 32, 3, p. 318-324 7 p.

Research output: Contribution to journalArticle

55 Scopus citations

A novel system for simultaneous in vivo tracking and biological assessment of leukemia cells and ex vivo generated leukemia-reactive cytotoxic T cells

Sauer, M. G., Ericson, M. E., Weigel, B. J., Herron, M. J., Panoskaltsis-Mortari, A., Kren, B. T., Levine, B. L., Serody, J. S., June, C. H., Taylor, P. A. & Blazar, B. R., Jun 1 2004, In : Cancer Research. 64, 11, p. 3914-3921 8 p.

Research output: Contribution to journalArticle

26 Scopus citations

B7 Expression on T Cells Down-Regulates Immune Responses through CTLA-4 Ligation via R-T Interactions

Taylor, P. A., Lees, C. J., Fournier, S., Allison, J. P., Sharpe, A. H. & Blazar, B. R., Jan 1 2004, In : Journal of Immunology. 172, 1, p. 34-39 6 p.

Research output: Contribution to journalArticle

108 Scopus citations

CD30/CD30 ligand (CD153) interaction regulates CD4+ T cell-mediated graft-versus-host disease

Blazar, B. R., Levy, R. B., Mak, T. W., Panoskaltsis-Mortari, A., Muta, H., Jones, M., Roskos, M., Serody, J. S., Yagita, H., Podack, E. R. & Taylor, P. A., Sep 1 2004, In : Journal of Immunology. 173, 5, p. 2933-2941 9 p.

Research output: Contribution to journalArticle

61 Scopus citations

Differential roles for CCR5 expression on donor T cells during graft-versus-host disease based on pretransplant conditioning

Wysocki, C. A., Burkett, S. B., Panoskaltsis-Mortari, A., Kirby, S. L., Luster, A. D., McKinnon, K., Blazar, B. R. & Serody, J. S., Jul 15 2004, In : Journal of Immunology. 173, 2, p. 845-854 10 p.

Research output: Contribution to journalArticle

100 Scopus citations
10 Scopus citations

Endothelial cell expression of tissue factor in sickle mice is augmented by hypoxia/reoxygenation and inhibited by lovastatin

Solovey, A., Kollander, R., Shet, A., Milbauer, L. C., Choong, S., Panoskaltsis-Mortari, A., Blazar, B. R., Kelm, R. J. & Hebbel, R. P., Aug 1 2004, In : Blood. 104, 3, p. 840-846 7 p.

Research output: Contribution to journalArticle

146 Scopus citations

Erratum: Inhibition of acute graft-versus-host disease with retention of graft-versus-tumor effects by the proteasome inhibitor bortezomib (Proceedings of the National Academy of Sciences of the United States of America (May 25, 2004) 101, 21 (8120-8125))

Sun, K., Welniak, L. A., Panoskaltsis-Mortari, A., O'Shaughnessy, M. J., Liu, H., Barao, I., Riordan, W., Sitcheran, R., Wysocki, C., Serody, J. S., Blazar, B. R., Sayers, T. J. & Murphy, W. J., Aug 24 2004, In : Proceedings of the National Academy of Sciences of the United States of America. 101, 34, 1 p.

Research output: Contribution to journalComment/debate

1 Scopus citations

Erratum: B7 expression on T cells down-regulates immune responses through CTLA-4 ligation via R-T interactions (Journal of Immunology (2004) 172 (34-39))

Taylor, P. A., Lees, C. J., Fournier, S., Allison, J. P., Sharpe, A. H. & Blazar, B. R., Aug 1 2004, In : Journal of Immunology. 173, 3, 1 p.

Research output: Contribution to journalComment/debate

Ex vivo depletion of alloreactive cells based on CFSE dye dilution, activation antigen selection, and dendritic cell stimulation

Godfrey, W. R., Krampf, M. R., Taylor, P. A. & Blazar, B. R., Feb 1 2004, In : Blood. 103, 3, p. 1158-1165 8 p.

Research output: Contribution to journalArticle

72 Scopus citations

Human plasmacytoid dendritic cells activated by CpG oligodeoxynucleotides induce the generation of CD4+CD25+ regulatory T cells

Moseman, E. A., Liang, X., Dawson, A. J., Panoskaltsis-Mortari, A., Krieg, A. M., Liu, Y. J., Blazar, B. R. & Chen, W., Oct 1 2004, In : Journal of Immunology. 173, 7, p. 4433-4442 10 p.

Research output: Contribution to journalArticle

505 Scopus citations

Inhibition of acute graft-versus-host disease with retention of graft-versus-tumor effects by the proteasome inhibitior bortezomib

Sun, K., Welniak, L. A., Panoskaltsis-Mortari, A., O'Shaughnessy, M. J., Liu, H., Barao, I., Riordan, W., Sitcheran, R., Wysocki, C., Serody, J. S., Blazar, B. R., Sayers, T. J. & Murphy, W. J., May 21 2004, In : Proceedings of the National Academy of Sciences of the United States of America. 101, 21, p. 8120-8125 6 p.

Research output: Contribution to journalArticle

220 Scopus citations

In vitro-expanded human CD4+CD25+ T-regulatory cells can markedly inhibit allogeneic dendritic cell-stimulated MLR cultures

Godfrey, W. R., Ge, Y. G., Spoden, D. J., Levine, B. L., June, C. H., Blazar, B. R. & Porter, S. B., Jul 15 2004, In : Blood. 104, 2, p. 453-461 9 p.

Research output: Contribution to journalArticle

250 Scopus citations

In vivo imaging of graft-versus-host-disease in mice

Panoskaltsis-Mortari, A., Price, A., Hermanson, J. R., Taras, E., Lees, C., Serody, J. S. & Blazar, B. R., May 1 2004, In : Blood. 103, 9, p. 3590-3598 9 p.

Research output: Contribution to journalArticle

113 Scopus citations

Ligation of CD137 receptor prevents and reverses established anergy of CD8+ cytolytic T lymphocytes in vivo

Wilcox, R. A., Tamada, K., Flies, D. B., Zhu, G., Chapoval, A. I., Blazar, B. R., Kast, W. M. & Chen, L., Jan 1 2004, In : Blood. 103, 1, p. 177-184 8 p.

Research output: Contribution to journalArticle

75 Scopus citations

L-selectinhi but not the L-selectinlo CD4 +25+ T-regulatory cells are potent inhibitors of GVHD and BM graft rejection

Taylor, P. A., Panoskaltsis-Mortari, A., Swedin, J. M., Lucas, P. J., Gress, R. E., Levine, B. L., June, C. H., Serody, J. S. & Blazar, B. R., Dec 1 2004, In : Blood. 104, 12, p. 3804-3812 9 p.

Research output: Contribution to journalArticle

278 Scopus citations

mAbs to Bacillus anthracis capsular antigen for immunoprotection in anthrax and detection of antigenemia

Kozel, T. R., Murphy, W. J., Brandt, S., Blazar, B. R., Lovchik, J. A., Thorkildson, P., Percival, A. & Lyons, C. R., Apr 6 2004, In : Proceedings of the National Academy of Sciences of the United States of America. 101, 14, p. 5042-5047 6 p.

Research output: Contribution to journalArticle

88 Scopus citations

Myeloperoxidase deficiency enhances inflammation after allogeneic marrow transplantation

Milla, C., Yang, S., Cornfield, D. N., Brennan, M. L., Hazen, S. L., Panoskaltsis-Mortari, A., Blazar, B. R. & Haddad, I. Y., Oct 2004, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 287, 4 31-4, p. L706-L714

Research output: Contribution to journalArticle

40 Scopus citations

Palifermin for oral mucositis after intensive therapy for hematologic cancers

Spielberger, R., Stiff, P., Bensinger, W., Gentile, T., Weisdorf, D., Kewalramani, T., Shea, T., Yanovich, S., Hansen, K., Noga, S., McCarty, J., LeMaistre, F., Sung, E. C., Blazar, B. R., Elhardt, D., Chen, M. G. & Emmanouilides, C., Dec 16 2004, In : New England Journal of Medicine. 351, 25, p. 2590-2598 9 p.

Research output: Contribution to journalArticle

671 Scopus citations

Post-BMT lung injury occurs independently of the expression of CCL2 or its receptor, CCR2, on host cells

Panoskaltsis-Mortari, A., Hermanson, J. R., Taras, E., Wangensteen, O. D., Charo, I. F., Rollins, B. J. & Blazar, B. R., Feb 2004, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 286, 2 30-2, p. L284-L292

Research output: Contribution to journalArticle

10 Scopus citations

Thrombopoietin cooperates with FLT3-ligand in the generation of plasmacytoid dendritic cell precursors from human hematopoietic progenitors

Chen, W., Antonenko, S., Sederstrom, J. M., Liang, X., Chan, A. S. H., Kanzler, H., Blom, B., Blazar, B. R. & Liu, Y. J., Apr 1 2004, In : Blood. 103, 7, p. 2547-2553 7 p.

Research output: Contribution to journalArticle

97 Scopus citations