1982 …2020

Research output per year

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Research Output

2007

The host immune response is essential for the beneficial effect of adult stem cells after myocardial ischemia

Tolar, J., Wang, X., Braunlin, E., McElmurry, R. T., Nakamura, Y., Bell, S., Xia, L., Zhang, J., Hu, Q., Panoskaltsis-Mortari, A., Zhang, J. & Blazar, B. R., Apr 1 2007, In : Experimental Hematology. 35, 4, p. 682-690 9 p.

Research output: Contribution to journalArticle

14 Scopus citations

The unexpected effect of cyclosporin A on CD56+CD16- and CD56+CD16+ natural killer cell subpopulations

Wang, H., Grzywacz, B., Sukovich, D., McCullar, V., Cao, Q., Lee, A. B., Blazar, B. R., Cornfield, D. N., Miller, J. S. & Verneris, M. R., Sep 1 2007, In : Blood. 110, 5, p. 1530-1539 10 p.

Research output: Contribution to journalArticle

109 Scopus citations
417 Scopus citations
2008

CD28 costimulation is essential for human T regulatory expansion and function

Golovina, T. N., Mikheeva, T., Suhoski, M. M., Aqui, N. A., Tai, V. C., Shan, X., Liu, R., Balcarcel, R. R., Fisher, N., Levine, B. L., Carroll, R. G., Warner, N., Blazar, B. R., June, C. H. & Riley, J. L., Aug 15 2008, In : Journal of Immunology. 181, 4, p. 2855-2868 14 p.

Research output: Contribution to journalArticle

117 Scopus citations

Circulating anticoagulant glycosaminoglycans in mucopolysaccharidosis type I

Tolar, J., Orchard, P. J., Key, N. S. & Blazar, B. R., May 2008, In : Journal of Thrombosis and Haemostasis. 6, 5, p. 893-895 3 p.

Research output: Contribution to journalArticle

5 Scopus citations

Combination Therapy Using IL-2 and Anti-CD25 Results in Augmented Natural Killer Cell-Mediated Antitumor Responses

Hallett, W. H. D., Ames, E., Álvarez, M., Barao, I., Taylor, P. A., Blazar, B. R. & Murphy, W. J., Oct 2008, In : Biology of Blood and Marrow Transplantation. 14, 10, p. 1088-1099 12 p.

Research output: Contribution to journalArticle

33 Scopus citations

Cytotoxic T cells reactive to an immunodominant leukemia-associated antigen can be specifically primed and expanded by combining a specific priming step with nonspecific large-scale expansion

Ghosh, A., Wolenski, M., Klein, C., Welte, K., Blazar, B. R. & Sauer, M. G., Feb 2008, In : Journal of Immunotherapy. 31, 2, p. 121-131 11 p.

Research output: Contribution to journalArticle

12 Scopus citations

Dendritic cell programming by cytomegalovirus stunts naive T cell responses via the PD-L1/PD-1 pathway

Benedict, C. A., Loewendorf, A., Garcia, Z., Blazar, B. R. & Janssen, E. M., Apr 1 2008, In : Journal of Immunology. 180, 7, p. 4836-4847 12 p.

Research output: Contribution to journalArticle

67 Scopus citations

Effects of donor T-cell trafficking and priming site on graft-versus-host disease induction by naive and memory phenotype CD4 T cells

Anderson, B. E., Taylor, P. A., McNiff, J. M., Jain, D., Demetris, A. J., Panoskaltsis-Mortari, A., Ager, A., Blazar, B. R., Shlomchik, W. D. & Shlomchik, M. J., May 15 2008, In : Blood. 111, 10, p. 5242-5251 10 p.

Research output: Contribution to journalArticle

59 Scopus citations

Expanded nonhuman primate Tregs exhibit a unique gene expression signature and potently downregulate alloimmune responses

Anderson, A., Martens, C. L., Hendrix, R., Stempora, L. L., Miller, W. P., Hamby, K., Russell, M., Strobert, E., Blazar, B. R., Pearson, T. C., Larsen, C. P. & Kean, L. S., Nov 2008, In : American Journal of Transplantation. 8, 11, p. 2252-2264 13 p.

Research output: Contribution to journalArticle

18 Scopus citations

Indoleamine 2,3-dioxygenase is a critical regulator of acute graft-versus-host disease lethality

Jasperson, L. K., Bucher, C., Panoskaltsis-Mortari, A., Taylor, P. A., Mellor, A. L., Munn, D. H. & Blazar, B. R., Mar 15 2008, In : Blood. 111, 6, p. 3257-3265 9 p.

Research output: Contribution to journalArticle

112 Scopus citations

Induction of transplantation tolerance by combining non-myeloablative conditioning with delivery of alloantigen by T cells

Tian, C., Yuan, X., Bagley, J., Blazar, B. R., Sayegh, M. H. & Iacomini, J., May 1 2008, In : Clinical Immunology. 127, 2, p. 130-137 8 p.

Research output: Contribution to journalArticle

8 Scopus citations

In situ identification of allospecific B cells using pentamers

Panoskaltsis-Mortari, A., Taylor, P. A., Riddle, M. J., Shlomchik, M. A. & R.Blazar, B., Apr 1 2008, In : Blood. 111, 7, p. 3904-3905 2 p.

Research output: Contribution to journalLetter

2 Scopus citations
75 Scopus citations
47 Scopus citations

Memory T cells in GVHD and GVL.

Anderson, B. E., Zheng, H., Taylor, P. A., Matte-Martone, C., McNiff, J. M., Jain, D., Demetris, A. J., Panoskaltsis-Mortari, A., Ager, A., Blazar, B. R., Shlomchik, M. J. & Shlomchik, W. D., Jan 2008, In : Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation. 14, 1 Suppl 1, p. 19-20 2 p.

Research output: Contribution to journalReview article

12 Scopus citations

Outgrowth of CD4low/negCD25+ T cells with suppressor function in CD4+CD25+ T cell cultures upon polyclonal stimulation ex vivo

Vogtenhuber, C., O'Shaughnessy, M. J., Vignali, D. A. A. & Blazar, B. R., Dec 15 2008, In : Journal of Immunology. 181, 12, p. 8767-8775 9 p.

Research output: Contribution to journalArticle

10 Scopus citations

Regulatory and conventional CD4+ T cells show differential effects correlating with PD-1 and B7-H1 expression after immunotherapy

Alderson, K. L., Zhou, Q., Berner, V., Wilkins, D. E. C., Weiss, J. M., Blazar, B. R., Welniak, L. A., Wiltrout, R. H., Redelman, D. & Murphy, W. J., Mar 1 2008, In : Journal of Immunology. 180, 5, p. 2981-2988 8 p.

Research output: Contribution to journalArticle

21 Scopus citations

Response: The role of G-CSF on the risk of graft-versus-host disease after donor lymphocyte infusions

Miller, J. S. & Blazar, B. R., May 15 2008, In : Blood. 111, 10, p. 5256-5257 2 p.

Research output: Contribution to journalLetter

Sleeping beauty transposon-mediated engineering of human primary T cells for therapy of CD19+ lymphoid malignancies

Huang, X., Guo, H., Kang, J., Choi, S., Zhou, T. C., Tammana, S., Lees, C. J., Li, Z. Z., Milone, M., Levine, B. L., Tolar, J., June, C. H., McIvor, R. S., Wagner, J. E., Blazar, B. R. & Zhou, X., Mar 2008, In : Molecular Therapy. 16, 3, p. 580-589 10 p.

Research output: Contribution to journalArticle

99 Scopus citations

Targeting of the CNS in MPS-IH using a nonviral transferrin-α-L-iduronidase fusion gene product

Osborn, M. J., McElmurry, R. T., Peacock, B., Tolar, J. & Blazar, B. R., Aug 1 2008, In : Molecular Therapy. 16, 8, p. 1459-1466 8 p.

Research output: Contribution to journalArticle

35 Scopus citations

The indoleamine 2,3-dioxygenase pathway is essential for human plasmacytoid dendritic cell-induced adaptive T regulatory cell generation

Chen, W., Liang, X., Peterson, A. J., Munn, D. H. & Blazar, B. R., Jan 1 2008, In : Journal of Immunology. 181, 8, p. 5396-5404 9 p.

Research output: Contribution to journalArticle

306 Scopus citations

Thymic stromal lymphopoietin is not necessary or sufficient to mediate the thymopoietic effects of keratinocyte growth factor [8]

Guimond, M., Leonard, W. J., Spolski, R., Rossi, S. W., Veenstra, R. G., Hollander, G. A., Mackall, C. L. & Blazar, B. R., Jan 15 2008, In : Blood. 111, 2, p. 969-970 2 p.

Research output: Contribution to journalLetter

4 Scopus citations

TLR agonists regulate alloresponses and uncover a critical role for donor APCs in allogeneic bone marrow rejection

Taylor, P. A., Ehrhardt, M. J., Lees, C. J., Panoskaltsis-Mortari, A., Krieg, A. M., Sharpe, A. H., Murphy, W. J., Serody, J. S., Hemmi, H., Akira, S., Levy, R. B. & Blazar, B. R., Oct 15 2008, In : Blood. 112, 8, p. 3508-3516 9 p.

Research output: Contribution to journalArticle

57 Scopus citations

Transgene expression and silencing in a tick cell line: A model system for functional tick genomics

Kurtti, T. J., Mattila, J. T., Herron, M. J., Felsheim, R. F., Baldridge, G. D., Burkhardt, N. Y., Blazar, B. R., Hackett, P. B., Meyer, J. M. & Munderloh, U. G., Oct 2008, In : Insect Biochemistry and Molecular Biology. 38, 10, p. 963-968 6 p.

Research output: Contribution to journalArticle

18 Scopus citations

Transient blockade of the inducible costimulator pathway generates long-term tolerance to factor VIII after nonviral gene transfer into hemophilia A mice

Peng, B., Ye, P., Blazar, B. R., Freeman, G. J., Rawlings, D. J., Ochs, H. D. & Miao, C. H., Sep 1 2008, In : Blood. 112, 5, p. 1662-1672 11 p.

Research output: Contribution to journalArticle

47 Scopus citations

Umbilical cord blood regulatory T-cell expansion and functional effects of tumor necrosis factor receptor family members OX40 and 4-1BB expressed on artificial antigen-presenting cells

Hippen, K. L., Harker-Murray, P., Porter, S. B., Merkel, S. C., Londer, A., Taylor, D. K., Bina, M., Panoskaltsis-Mortari, A., Rubinstein, P., Van Rooijen, N., Golovina, T. N., Suhoski, M. M., Miller, J. S., Wagner, J. E., June, C. H., Riley, J. L. & Blazar, B. R., Oct 1 2008, In : Blood. 112, 7, p. 2847-2857 11 p.

Research output: Contribution to journalArticle

109 Scopus citations
33 Scopus citations
2009

Acute graft-versus-host disease: From the bench to the bedside

Socié, G. & Blazar, B. R., Nov 12 2009, In : Blood. 114, 20, p. 4327-4336 10 p.

Research output: Contribution to journalArticle

198 Scopus citations
148 Scopus citations

Altered B-cell homeostasis and excess BAFF in human chronic graft-versus-host disease

Sarantopoulos, S., Stevenson, K. E., Kim, H. T., Cutler, C. S., Bhuiya, N. S., Schowalter, M., Ho, V. T., Alyea, E. P., Koreth, J., Blazar, B. R., Soiffer, R. J., Antin, J. H. & Ritz, J., 2009, In : Blood. 113, 16, p. 3865-3874 10 p.

Research output: Contribution to journalArticle

204 Scopus citations

Amelioration of epidermolysis bullosa by transfer of wild-type bone marrow cells

Tolar, J., Akemi, I. Y., Riddle, M., McElmurry, R. T., Osborn, M., Xia, L., Lund, T., Slattery, C., Uitto, J., Christiano, A. M., Wagner, J. E. & Blazar, B. R., Jan 29 2009, In : Blood. 113, 5, p. 1167-1174 8 p.

Research output: Contribution to journalArticle

122 Scopus citations

Depletion of endogenous tumor-associated regulatory T cells improves the efficacy of adoptive cytotoxic T-cell immunotherapy in murine acute myeloid leukemia

Zhou, Q., Bucher, C., Munger, M. E., Highfill, S. L., Tolar, J., Munn, D. H., Levine, B. L., Riddle, M., June, C. H., Vallera, D. A., Weigel, B. J. & Blazar, B. R., Oct 29 2009, In : Blood. 114, 18, p. 3793-3802 10 p.

Research output: Contribution to journalArticle

81 Scopus citations

Donor T cells primed on leukemia lysate-pulsed recipient APCs mediate strong graft-versus-leukemia effects across MHC barriers in full chimeras

Ghosh, A., Koestner, W., Hapke, M., Schlaphoff, V., Länger, F., Baumann, R., Koenecke, C., Cornberg, M., Welte, K., Blazar, B. R. & Sauer, M. G., 2009, In : Blood. 113, 18, p. 4440-4448 9 p.

Research output: Contribution to journalArticle

14 Scopus citations

Engineering lymphocyte subsets: Tools, trials and tribulations

June, C. H., Blazar, B. R. & Riley, J. L., Oct 2009, In : Nature Reviews Immunology. 9, 10, p. 704-716 13 p.

Research output: Contribution to journalReview article

160 Scopus citations

Expression of telomerase and telomere length are unaffected by either age or limb regeneration in Danio rerio

Lund, T. C., Glass, T. J., Tolar, J. & Blazar, B. R., Nov 6 2009, In : PloS one. 4, 11, e7688.

Research output: Contribution to journalArticle

38 Scopus citations

Ex vivo expanded non-human primate regulatory t cells suppress xeno-antigenic responses through both cytokine-and contact-dependent pathways

Johnson, J. L., Hennessy, E. A., Pahuja, A., Graham, M., Blazar, B. R., Hering, B. J. & Bansal-Pakala, P., 2009, In : Xenotransplantation. 16, 5, p. 387 1 p.

Research output: Contribution to journalArticle

Ex vivo inhibition of NF-κB signaling in alloreactive T-cells prevents graft-versus-host disease

O'Shaughnessy, M. J., Vogtenhuber, C., Sun, K., Sitcheran, R., Baldwin, A. S., Murphy, W. J., Dang, L., Jaffee, B., Palmer, E., Serody, J. S. & Blazar, B. R., Mar 2009, In : American Journal of Transplantation. 9, 3, p. 452-462 11 p.

Research output: Contribution to journalArticle

14 Scopus citations
6 Scopus citations

Genetic trickery - Escape of leukemia from immune attack

Barrett, J. & Blazar, B. R., Jul 30 2009, In : New England Journal of Medicine. 361, 5, p. 524-525 2 p.

Research output: Contribution to journalEditorial

5 Scopus citations

Human T Regulatory Cell Therapy: Take a Billion or So and Call Me in the Morning

Riley, J. L., June, C. H. & Blazar, B. R., May 22 2009, In : Immunity. 30, 5, p. 656-665 10 p.

Research output: Contribution to journalReview article

324 Scopus citations

IL-21 blockade reduces graft-versus-host disease mortality by supporting inducible T regulatory cell generation

Bucher, C., Koch, L., Vogtenhuber, C., Goren, E., Munger, M., Panoskaltsis-Mortari, A., Sivakumar, P. & Blazar, B. R., Dec 17 2009, In : Blood. 114, 26, p. 5375-5384 10 p.

Research output: Contribution to journalArticle

104 Scopus citations
36 Scopus citations

Inactivation of the adenosine A2A receptor protects apolipoprotein E-deficient mice from atherosclerosis

Wang, H., Zhang, W., Zhu, C., Bucher, C., Blazar, B. R., Zhang, C., Chen, J. F., Linden, J., Wu, C. & Huo, Y., Jul 1 2009, In : Arteriosclerosis, thrombosis, and vascular biology. 29, 7, p. 1046-1052 7 p.

Research output: Contribution to journalArticle

50 Scopus citations

Inducing the tryptophan catabolic pathway, indoleamine 2,3-dioxygenase (IDO), for suppression of graft-versus-host disease (GVHD) lethality

Koch, L. K., Bucher, C., Panoskaltsis-Mortari, A., Mellor, A. L., Munn, D. H. & Blazar, B. R., Dec 3 2009, In : Blood. 114, 24, p. 5062-5070 9 p.

Research output: Contribution to journalArticle

98 Scopus citations

In vitro differentiated TH17 cells mediate lethal acute graft-versus-host disease with severe cutaneous and pulmonary pathologic manifestations

Carlson, M. J., West, M. L., Coghill, J. M., Panoskaltsis-Mortari, A., Blazar, B. R. & Serody, J. S., Feb 5 2009, In : Blood. 113, 6, p. 1365-1374 10 p.

Research output: Contribution to journalArticle

219 Scopus citations
16 Scopus citations

Multipotent adult progenitor cells can suppress graft-versus-host disease via prostaglandin E2 synthesis and only if localized to sites of allopriming

Highfill, S. L., Kelly, R. M., O'Shaughnessy, M. J., Zhou, Q., Xia, L., Panoskaltsis-Mortari, A., Taylor, P. A., Tolar, J. & Blazar, B. R., 2009, In : Blood. 114, 3, p. 693-701 9 p.

Research output: Contribution to journalArticle

48 Scopus citations

Myeloablative hematopoietic cell transplantation for acute lymphoblastic leukemia: Analysis of graft sources and long-term outcome

Tomblyn, M. B., Arora, M., Baker, K. S., Blazar, B. R., Brunstein, C. G., Burns, L. J., Defor, T. E., Dusenbery, K. E., Kaufman, D. S., Kersey, J. H., MacMillan, M. L., McGlave, P. B., Miller, J. S., Orchard, P. J., Slungaard, A., Tomblyn, M. R., Vercellotti, G. M., Verneris, M. R., Wagner, J. E. & Weisdorf, D. J., Aug 1 2009, In : Journal of Clinical Oncology. 27, 22, p. 3634-3641 8 p.

Research output: Contribution to journalArticle

63 Scopus citations
100 Scopus citations