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Research Output 1977 2016

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Article
2015
4 Citations (Scopus)

Caspase-2 modulates osteoclastogenesis through down-regulating oxidative stress

Callaway, D. A., Riquelme, M. A., Sharma, R., Lopez-Cruzan, M., Herman, B. A. & Jiang, J. X., Jul 1 2015, In : Bone. 76, p. 40-48 9 p.

Research output: Contribution to journalArticle

Caspase 2
Osteoclasts
Osteogenesis
Oxidative Stress
Reactive Oxygen Species
2014
30 Citations (Scopus)

A nonapoptotic role for CASP2/caspase 2: Modulation of autophagy

Tiwari, M., Sharma, L. K., Vanegas, D., Callaway, D. A., Bai, Y., Lechleiter, J. D. & Herman, B., Jan 1 2014, In : Autophagy. 10, 6, p. 1054-1070 17 p.

Research output: Contribution to journalArticle

Caspase 2
Autophagy
Up-Regulation
Fibroblasts
AMP-Activated Protein Kinases
13 Citations (Scopus)

Caspase-2 maintains bone homeostasis by inducing apoptosis of oxidatively-damaged osteoclasts

Sharma, R., Callaway, D., Vanegas, D., Bendele, M., Lopez-Cruzan, M., Horn, D., Guda, T., Fajardo, R., Abboud-Werner, S. & Herman, B., Apr 1 2014, In : PLoS One. 9, 4, e93696.

Research output: Contribution to journalArticle

caspase-2
Caspase 2
osteoclasts
Osteoclasts
Oxidative stress
2013
9 Citations (Scopus)

Loss of caspase-2 accelerates age-dependent alterations in mitochondrial production of reactive oxygen species

Lopez-Cruzan, M. & Herman, B., Apr 1 2013, In : Biogerontology. 14, 2, p. 121-130 10 p.

Research output: Contribution to journalArticle

Caspase 2
Reactive Oxygen Species
Hepatocytes
Oxidative Stress
Antimycin A
2011
3 Citations (Scopus)

A knockout of the caspase 2 gene produces increased resistance of the nigrostriatal dopaminergic pathway to MPTP-induced toxicity

Tiwari, M., Herman, B. & Morgan, W. W., Jun 1 2011, In : Experimental Neurology. 229, 2, p. 421-428 8 p.

Research output: Contribution to journalArticle

Caspase 2
1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine
Genes
Neurons
Substantia Nigra
48 Citations (Scopus)

Loss of caspase-2-dependent apoptosis induces autophagy after mitochondrial oxidative stress in primary cultures of young adult cortical neurons

Tiwari, M., Lopez-Cruzan, M., Morgan, W. W. & Herman, B., Mar 11 2011, In : Journal of Biological Chemistry. 286, 10, p. 8493-8506 14 p.

Research output: Contribution to journalArticle

Caspase 2
Rotenone
Oxidative stress
Autophagy
Neurons
2008
11 Citations (Scopus)
AIDS-Related Complex
Oxidative stress
Oxidative Stress
Cells
Apoptosis
9 Citations (Scopus)

Nonlinear scaling analysis of glucose metabolism in normal and cancer cells

Ramanujan, V. K. & Herman, B. A., Dec 1 2008, In : Journal of Biomedical Optics. 13, 3, 031219.

Research output: Contribution to journalArticle

metabolism
Metabolism
glucose
Glucose
cancer
21 Citations (Scopus)

Spatially resolved fluorescence lifetime mapping of enzyme kinetics in living cells

Ramanujan, V. K., Jo, J. A., Cantu, G. & Herman, B. A., Jun 1 2008, In : Journal of Microscopy. 230, 3, p. 329-338 10 p.

Research output: Contribution to journalArticle

Fluorescence
Enzymes
NAD
Photons
Artifacts
2007
15 Citations (Scopus)

Aging process modulates nonlinear dynamics in liver cell metabolism

Ramanujan, V. K. & Herman, B. A., Jun 29 2007, In : Journal of Biological Chemistry. 282, 26, p. 19217-19226 10 p.

Research output: Contribution to journalArticle

Nonlinear Dynamics
Metabolism
Liver
Energy Metabolism
Aging of materials
59 Citations (Scopus)

Caspase-2 deficiency enhances aging-related traits in mice

Zhang, Y., Padalecki, S. S., Chaudhuri, A. R., De Waal, E., Goins, B. A., Grubbs, B., Ikeno, Y., Richardson, A., Mundy, G. R. & Herman, B., Feb 1 2007, In : Mechanisms of Ageing and Development. 128, 2, p. 213-221 9 p.

Research output: Contribution to journalArticle

Caspase 2
Aging of materials
Apoptosis
Animals
Premature Aging
2006
28 Citations (Scopus)

ARC protects rat cardiomyocytes against oxidative stress through inhibition of caspase-2 mediated mitochondrial pathway

Zhang, Y. Q. & Herman, B., Oct 1 2006, In : Journal of Cellular Biochemistry. 99, 2, p. 575-588 14 p.

Research output: Contribution to journalArticle

Caspase 2
AIDS-Related Complex
Oxidative stress
Cardiac Myocytes
Rats
17 Citations (Scopus)

Scaling behavior in mitochondrial redox fluctuations

Ramanujan, V. K., Biener, G. & Herman, B. A., Jan 1 2006, In : Biophysical Journal. 90, 10

Research output: Contribution to journalArticle

NAD
Oxidation-Reduction
Mitochondria
Earthquakes
Nonlinear Dynamics
10 Citations (Scopus)

Spatio-temporal kinetics of growth hormone receptor signaling in single cells using FRET microscopy

Biener-Ramanujan, E., Ramanujan, V. K., Herman, B. & Gertler, A., Aug 1 2006, In : Growth Hormone and IGF Research. 16, 4, p. 247-257 11 p.

Research output: Contribution to journalArticle

Somatotropin Receptors
Fluorescence Resonance Energy Transfer
Dimerization
Growth Hormone
Microscopy
8 Citations (Scopus)

Spectral kinetics ratiometry: A simple approach for real-time monitoring of fluorophore distributions in living cells

Ramanujan, V. K., Biener-Ramanujan, E., Armmer, K., Centonze, V. E. & Herman, B. A., Aug 1 2006, In : Cytometry Part A. 69, 8, p. 912-919 8 p.

Research output: Contribution to journalArticle

Libraries
Photobleaching
Biophysical Phenomena
Mitochondrial Membranes
Caspases
2005
72 Citations (Scopus)

Identification of the hydrophobia strand in the A-B loop of leptin as major binding site III: Implications for large-scale preparation of potent recombinant human and ovine leptin antagonists

Niv-Spector, L., Gonen-Berger, D., Gourdou, I., Biener, E., Gussakovsky, E. E., Benomar, Y., Ramanujan, K. V., Taouis, M., Herman, B., Callebaut, I., Djiane, J. & Gertler, A., Oct 15 2005, In : Biochemical Journal. 391, 2, p. 221-230 10 p.

Research output: Contribution to journalArticle

Rabies
Leptin
Sheep
Binding Sites
Leptin Receptors

Monitoring mitochondrial caspase-2 activity in intact cells by streak camera based fluorescence lifetime imaging microscopy

Herman, B. A., Zhang, J. H., Ramanujan, V. K., Lopez-Cruzan, M., Medina, S. & Centonze, V. E., Aug 25 2005, In : Microscopy and Microanalysis. 11, SUPPL. 2, p. 8-9 2 p.

Research output: Contribution to journalArticle

Streak cameras
streak cameras
Microscopic examination
Fluorescence
microscopy
45 Citations (Scopus)

Multiphoton fluorescence lifetime contrast in deep tissue imaging: Prospects in redox imaging and disease diagnosis

Ramanujan, V. K., Zhang, J. H., Biener, E. & Herman, B., Sep 1 2005, In : Journal of biomedical optics. 10, 5, 051407.

Research output: Contribution to journalArticle

Oxidation-Reduction
Fluorescence
Tissue
Imaging techniques
life (durability)
31 Citations (Scopus)

Quantitative FRET imaging of leptin receptor oligomerization kinetics in single cells

Biener, E., Charlier, M., Ramanujan, V. K., Daniel, N., Eisenberg, A., Bjørbaek, C., Herman, B., Gertler, A. & Djiane, J., Dec 1 2005, In : Biology of the Cell. 97, 12, p. 905-919 15 p.

Research output: Contribution to journalArticle

Leptin Receptors
Fluorescence Resonance Energy Transfer
Leptin
Cell Membrane
Proteins
1 Citation (Scopus)

Quantitative FRET imaging of leptin receptor oligomerization kinetics in single cells

Ramanujan, V. K., Biener, E., Charlier, M., Daniel, N., Eisenberg, A., Herman, B., Djiane, J. & Gertler, A., Aug 25 2005, In : Microscopy and Microanalysis. 11, SUPPL. 2, p. 10-11 2 p.

Research output: Contribution to journalArticle

Oligomerization
Imaging techniques
Kinetics
kinetics
cells
2004
8 Citations (Scopus)

Detection of mitochondrial caspase activity in real time in situ in live cells

Zhang, Y., Haskins, C., Lopez-Cruzan, M., Zhang, J., Centonze, V. E. & Herman, B., Aug 1 2004, In : Microscopy and Microanalysis. 10, 4, p. 442-448 7 p.

Research output: Contribution to journalArticle

proteins
Proteins
cells
Fluorophores
Cell death
33 Citations (Scopus)

Discrimination of depolarized from polarized mitochondria by confocal fluorescence resonance energy transfer

Elmore, S. P., Nishimura, Y., Qian, T., Herman, B. & Lemasters, J. J., Feb 15 2004, In : Archives of Biochemistry and Biophysics. 422, 2, p. 145-152 8 p.

Research output: Contribution to journalArticle

Fluorescence Resonance Energy Transfer
Mitochondria
Fluorescence
Depolarization
Hepatocytes
145 Citations (Scopus)

Oxidative stress-induced apoptosis is associated with alterations in mitochondrial caspase activity and Bcl-2-dependent alterations in mitochondrial pH (pHm)

Takahashi, A., Masuda, A., Sun, M., Centonze, V. E. & Herman, B., Feb 15 2004, In : Brain Research Bulletin. 62, 6, p. 497-504 8 p.

Research output: Contribution to journalArticle

Caspases
Oxidative Stress
Apoptosis
Mitochondria
Cytochromes c
39 Citations (Scopus)

Transactivation of erbB2 by short and long isoforms of leptin receptors

Eisenberg, A., Biener, E., Charlier, M., Krishnan, R. V., Djiane, J., Herman, B. & Gertler, A., May 7 2004, In : FEBS Letters. 565, 1-3, p. 139-142 4 p.

Research output: Contribution to journalArticle

Leptin Receptors
Transcriptional Activation
Protein Isoforms
Leptin
Phosphotransferases
147 Citations (Scopus)

Transgenic mice overexpressing glutathione peroxidase 4 are protected against oxidative stress-induced apoptosis

Ran, Q., Liang, H., Gu, M., Qi, W., Walter, C. A., Roberts, L. J., Herman, B., Richardson, A. & Van Remmen, H., Dec 31 2004, In : Journal of Biological Chemistry. 279, 53, p. 55137-55146 10 p.

Research output: Contribution to journalArticle

phospholipid-hydroperoxide glutathione peroxidase
Oxidative stress
Transgenic Mice
Oxidative Stress
Apoptosis
2003
88 Citations (Scopus)

Development of a multiphoton fluorescence lifetime imaging microscopy system using a streak camera

Krishnan, R. V., Saitoh, H., Terada, H., Centonze, V. E. & Herman, B., May 1 2003, In : Review of Scientific Instruments. 74, 5, p. 2714-2721 8 p.

Research output: Contribution to journalArticle

Streak cameras
streak cameras
Microscopic examination
Fluorescence
microscopy
37 Citations (Scopus)

Fluorescence resonance energy transfer imaging microscopy

Centonze, V. E., Sun, M., Masuda, A., Gerritsen, H. & Herman, B., Jan 1 2003, In : Methods in Enzymology. 360, p. 542-560 19 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

FRET and FLIM microscopy in the study of the role of oxidative stress and apoptosis in aging

Zhang, Y., Zhang, J., Masuda, A., Lopez-Cruzan, M., Centonze, V., Krishnan, R. V. & Herman, B., Sep 4 2003, In : Microscopy and Microanalysis. 9, SUPPL. 2, p. 226-227 2 p.

Research output: Contribution to journalArticle

Oxidative stress
apoptosis
Cell death
Microscopic examination
Aging of materials
34 Citations (Scopus)
STAT1 Transcription Factor
Prolactin Receptors
Placental Lactogen
Somatotropin Receptors
Fluorescence Resonance Energy Transfer
24 Citations (Scopus)

Probing subtle fluorescence dynamics in cellular proteins by streak camera based fluorescence lifetime imaging microscopy

Krishnan, R. V., Biener, E., Zhang, J. H., Heckel, R. & Herman, B., Dec 1 2003, In : Applied Physics Letters. 83, 22, p. 4658-4660 3 p.

Research output: Contribution to journalArticle

streak cameras
temporal resolution
spatial resolution
microscopy
proteins
2002
61 Citations (Scopus)

Age-associated increases in the activity of multiple caspases in Fisher 344 rat organs

Zhang, Y., Chong, E. & Herman, B., Jun 1 2002, In : Experimental Gerontology. 37, 6, p. 777-789 13 p.

Research output: Contribution to journalArticle

Caspases
Liver
Rats
Apoptosis
Caspase 6

Fluorescence microscopy.

Herman, B., May 1 2002, In : Current protocols in immunology / edited by John E. Coligan ... [et al.]. Chapter 21

Research output: Contribution to journalArticle

Fluorescence Microscopy
Fluorescence
Cellular Structures
Light

FRET imaging microscopy

Herman, B., Sun, M., Masuda, A., Gerritsen, H. & Centonze, V., Jan 1 2002, In : Proceedings of SPIE - The International Society for Optical Engineering. 4620, p. 96-105 10 p.

Research output: Contribution to journalArticle

Energy Transfer
resonance fluorescence
Microscopy
Fluorescence
Microscopic examination
28 Citations (Scopus)

Human papillomavirus type 16 E6 and E7 gene variations in Indian cervical cancer

Pillai, M. R., Sreevidya, S., Pollock, B. H., Jayaprakash, P. G. & Herman, B., Jan 1 2002, In : Gynecologic oncology. 87, 3, p. 268-273 6 p.

Research output: Contribution to journalArticle

Human papillomavirus 16
Uterine Cervical Neoplasms
Genes
Mutation
Neoplasms
19 Citations (Scopus)

Polymorphism at codon 72 of p53, human papillomavirus, and cervical cancer in South India

Pillai, M. R., Sreevidya, S., Pollock, B. H., Jayaprakash, P. G. & Herman, B., Dec 19 2002, In : Journal of Cancer Research and Clinical Oncology. 128, 11, p. 627-631 5 p.

Research output: Contribution to journalArticle

Codon
Uterine Cervical Neoplasms
India
Uterine Cervical Dysplasia
Papillomavirus Infections
14 Citations (Scopus)

Preparation and expression of biologically active prolactin and growth hormone receptors and suppressor of cytokine signaling proteins 1, 2, 3, and 6 tagged with cyan and yellow fluorescent proteins

Ben-Yair, L., Slaaby, R., Herman, A., Cohen, Y., Biener, E., Moran, N., Yoshimura, A., Whittaker, J., De Meyts, P., Herman, B. & Gertler, A., Nov 20 2002, In : Protein Expression and Purification. 25, 3, p. 456-464 9 p.

Research output: Contribution to journalArticle

Somatotropin Receptors
Prolactin
Plasmids
HEK293 Cells
Proteins
2000
45 Citations (Scopus)

Differential sensitivity of mouse neural crest cells to ethanol-induced toxicity

Chen, S. Y., Periasamy, A., Yang, B., Herman, B., Jacobson, K. & Sulik, K. K., Jan 1 2000, In : Alcohol. 20, 1, p. 75-81 7 p.

Research output: Contribution to journalArticle

Neural Crest
Toxicity
Ethanol
Membrane Lipids
death
35 Citations (Scopus)
Human papillomavirus 16
Caspases
Keratinocytes
Chemical activation
Apoptosis
1 Citation (Scopus)

Localization of rat liver group IIA phospholipase A2 in secretory pathways: Green fluorescent protein approach

Zhang, Y., Lemasters, J. & Herman, B., Mar 1 2000, In : Microscopy and Microanalysis. 6, 2, p. 150-155 6 p.

Research output: Contribution to journalArticle

Mitochondria
mitochondria
liver
Liver
rats
7 Citations (Scopus)

Quantitative fluorescence microscopy

Centonze, V. E., Takahashi, A., Casanova, E. & Herman, B., Jan 1 2000, In : Journal of Histotechnology. 23, 3, p. 229-234 6 p.

Research output: Contribution to journalArticle

Fluorescence Resonance Energy Transfer
Antibody Specificity
Haptens
Optical Imaging
Fluorescence Microscopy
1999
29 Citations (Scopus)

Confocal microscopy of the mitochondrial permeability transition in necrotic and apoptotic cell death

Lemasters, J. J., Qian, T., Trost, L. C., Herman, B., Cascio, W. E., Bradham, C. A., Brenner, D. A. & Nieminen, A. L., Jan 1 1999, In : Biochemical Society symposium. 66, p. 205-222 18 p.

Research output: Contribution to journalArticle

Confocal microscopy
Cell death
Confocal Microscopy
Cyclosporine
Toxicity
105 Citations (Scopus)

Novel mutant green fluorescent protein protease substrates reveal the activation of specific caspases during apoptosis

Mahajan, N. P., Harrison-Shostak, D. C., Michaux, J. & Herman, B., Jan 1 1999, In : Chemistry and Biology. 6, 6, p. 401-409 9 p.

Research output: Contribution to journalArticle

Mutant Proteins
Caspase 1
Caspases
Green Fluorescent Proteins
Peptide Hydrolases
43 Citations (Scopus)

Secretory group IIA phospholipase A2 generates anti-apoptotic survival signals in kidney fibroblasts

Zhang, Y., Lemasters, J. & Herman, B., Sep 24 1999, In : Journal of Biological Chemistry. 274, 39, p. 27726-27733 8 p.

Research output: Contribution to journalArticle

Group II Phospholipases A2
Fibroblasts
Phospholipases A2
Kidney
Cricetinae
129 Citations (Scopus)

The mitochondrial permeability transition mediates both necrotic and apoptotic death of hepatocytes exposed to Br-A23187

Qian, T., Herman, B. & Lemasters, J. J., Jan 15 1999, In : Toxicology and Applied Pharmacology. 154, 2, p. 117-125 9 p.

Research output: Contribution to journalArticle

Calcimycin
Hepatocytes
Permeability
Cells
Oligomycins
1998
250 Citations (Scopus)

Bcl-2 and bax interactions in mitochondria probed with green fluorescent protein and fluorescence resonance energy transfer

Mahajan, N. P., Linder, K., Berry, G., Gordon, G. W., Heim, R. & Herman, B., Jun 1 1998, In : Nature biotechnology. 16, 6, p. 547-552 6 p.

Research output: Contribution to journalArticle

Fluorescence Resonance Energy Transfer
Mitochondria
Green Fluorescent Proteins
Proteins
Fusion reactions
49 Citations (Scopus)

Mitochondrial Ca2+ transients in cardiac myocytes during the excitation-contraction cycle: Effects of pacing and hormonal stimulation

Ohata, H., Chacon, E., Tesfai, S. A., Harper, I. S., Herman, B. & Lemasters, J. J., Jan 1 1998, In : Journal of Bioenergetics and Biomembranes. 30, 3, p. 207-222 16 p.

Research output: Contribution to journalArticle

Cardiac Myocytes
Mitochondria
Cytosol
Isoproterenol
Confocal Microscopy
783 Citations (Scopus)

Protection against fatal sindbis virus encephalitis by Beclin, a novel Bcl-2-interacting protein

Liang, X. H., Kleeman, L. K., Jiang, H. H., Gordon, G., Goldman, J. E., Berry, G., Herman, B. & Levine, B., Nov 1 1998, In : Journal of Virology. 72, 11, p. 8586-8596 11 p.

Research output: Contribution to journalArticle

Sindbis virus
Sindbis Virus
Encephalitis
encephalitis
mice
654 Citations (Scopus)

Quantitative fluorescence resonance energy transfer measurements using fluorescence microscopy

Gordon, G. W., Berry, G., Liang, X. H., Levine, B. & Herman, B., Jan 1 1998, In : Biophysical journal. 74, 5, p. 2702-2713 12 p.

Research output: Contribution to journalArticle

Fluorescence Resonance Energy Transfer
Fluorescence Microscopy
Tissue Donors
Microscopy
Fluorescence
110 Citations (Scopus)

Regulation of a calcium-dependent tyrosine kinase in vascular smooth muscle cells by angiotensin II and platelet-derived growth factor. Dependence on calcium and the actin cytoskeleton

Brinson, A. E., Harding, T., Diliberto, P. A., He, Y., Li, X., Hunter, D., Herman, B., Earp, H. S. & Graves, L. M., Jan 16 1998, In : Journal of Biological Chemistry. 273, 3, p. 1711-1718 8 p.

Research output: Contribution to journalArticle

Phosphorylation
Platelet-Derived Growth Factor
Actin Cytoskeleton
Vascular Smooth Muscle
Angiotensin II
1129 Citations (Scopus)

The mitochondrial permeability transition in cell death: A common mechanism in necrosis, apoptosis and autophagy

Lemasters, J. J., Nieminen, A. L., Qian, T., Trost, L. C., Elmore, S. P., Nishimura, Y., Crowe, R. A., Cascio, W. E., Bradham, C. A., Brenner, D. A. & Herman, B., Aug 10 1998, In : Biochimica et Biophysica Acta - Bioenergetics. 1366, 1-2, p. 177-196 20 p.

Research output: Contribution to journalArticle

Mitochondria
Autophagy
Cell death
Permeability
Cell Death