Brian Herman

Willing to speak to media

1977 …2020

Research output per year

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Research Output

2016

Caspase-2 resides in the mitochondria and mediates apoptosis directly from the mitochondrial compartment

Lopez-Cruzan, M., Sharma, R., Tiwari, M., Karbach, S., Holstein, D., Martin, C. R., Lechleiter, J. D. & Herman, B., Dec 12 2016, In : Cell Death Discovery. 2, 1, 16005.

Research output: Contribution to journalArticle

Open Access
12 Scopus citations

Erratum: Caspase-2 modulates osteoclastogenesis through down-regulating oxidative stress (Bone (2015) 76 (40–48) (S8756328215000848) (10.1016/j.bone.2015.03.006))

Callaway, D. A., Riquelme, M. A., Sharma, R., Lopez-Cruzan, M., Herman, B. A. & Jiang, J. X., Dec 1 2016, In : Bone. 93, p. 233-234 2 p.

Research output: Contribution to journalComment/debate

2015

Caspase-2 modulates osteoclastogenesis through down-regulating oxidative stress

Callaway, D. A., Riquelme, M. A., Sharma, R., Lopez-Cruzan, M., Herman, B. A. & Jiang, J. X., Jul 1 2015, In : Bone. 76, p. 40-48 9 p.

Research output: Contribution to journalArticle

5 Scopus citations
2014

A nonapoptotic role for CASP2/caspase 2: Modulation of autophagy

Tiwari, M., Sharma, L. K., Vanegas, D., Callaway, D. A., Bai, Y., Lechleiter, J. D. & Herman, B., Jun 2014, In : Autophagy. 10, 6, p. 1054-1070 17 p.

Research output: Contribution to journalArticle

35 Scopus citations

Caspase-2 maintains bone homeostasis by inducing apoptosis of oxidatively-damaged osteoclasts

Sharma, R., Callaway, D., Vanegas, D., Bendele, M., Lopez-Cruzan, M., Horn, D., Guda, T., Fajardo, R., Abboud-Werner, S. & Herman, B., Apr 1 2014, In : PloS one. 9, 4, e93696.

Research output: Contribution to journalArticle

14 Scopus citations
2013

Loss of caspase-2 accelerates age-dependent alterations in mitochondrial production of reactive oxygen species

Lopez-Cruzan, M. & Herman, B., Apr 1 2013, In : Biogerontology. 14, 2, p. 121-130 10 p.

Research output: Contribution to journalArticle

10 Scopus citations

Single-Cell Microscopic Techniques for Studying Toxic Injury

Lemasters, J. J., Nieminen, A. L., Chacon, E., Bond, J. M., Harper, I., Reece, J. M. & Herman, B., Jan 1 2013, In Vitro Toxicity Indicators. Elsevier Inc., Vol. 1. p. 438-455 18 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2012

Guidelines for the use and interpretation of assays for monitoring autophagy

Klionsky, D. J., Abdalla, F. C., Abeliovich, H., Abraham, R. T., Acevedo-Arozena, A., Adeli, K., Agholme, L., Agnello, M., Agostinis, P., Aguirre-Ghiso, J. A., Ahn, H. J., Ait-Mohamed, O., Ait-Si-Ali, S., Akematsu, T., Akira, S., Al-Younes, H. M., Al-Zeer, M. A., Albert, M. L., Albin, R. L., Alegre-Abarrategui, J. & 1,249 others, Aleo, M. F., Alirezaei, M., Almasan, A., Almonte-Becerril, M., Amano, A., Amaravadi, R., Amarnath, S., Amer, A. O., Andrieu-Abadie, N., Anantharam, V., Ann, D. K., Anoopkumar-Dukie, S., Aoki, H., Apostolova, N., Arancia, G., Aris, J. P., Asanuma, K., Asare, N. Y. O., Ashida, H., Askanas, V., Askew, D. S., Auberger, P., Baba, M., Backues, S. K., Baehrecke, E. H., Bahr, B. A., Bai, X. Y., Bailly, Y., Baiocchi, R., Baldini, G., Balduini, W., Ballabio, A., Bamber, B. A., Bampton, E. T. W., Bánhegyi, G., Bartholomew, C. R., Bassham, D. C., Bast, R. C., Batoko, H., Bay, B. H., Beau, I., Béchet, D. M., Begley, T. J., Behl, C., Behrends, C., Bekri, S., Bellaire, B., Bendall, L. J., Benetti, L., Berliocchi, L., Bernardi, H., Bernassola, F., Besteiro, S., Bhatia-Kissova, I., Bi, X., Biard-Piechaczyk, M., Blum, J. S., Boise, L. H., Bonaldo, P., Boone, D. L., Bornhauser, B. C., Bortoluci, K. R., Bossis, I., Bost, F., Bourquin, J. P., Boya, P., Boyer-Guittaut, M., Bozhkov, P. V., Brady, N. R., Brancolini, C., Brech, A., Brenman, J. E., Brennand, A., Bresnick, E. H., Brest, P., Bridges, D., Bristol, M. L., Brookes, P. S., Brown, E. J., Brumell, J. H., Brunetti-Pierri, N., Brunk, U. T., Bulman, D. E., Bultman, S. J., Bultynck, G., Burbulla, L. F., Bursch, W., Butchar, J. P., Buzgariu, W., Bydlowski, S. P., Cadwell, K., Cahová, M., Cai, D., Cai, J., Cai, Q., Calabretta, B., Calvo-Garrido, J., Camougrand, N., Campanella, M., Campos-Salinas, J., Candi, E., Cao, L., Caplan, A. B., Carding, S. R., Cardoso, S. M., Carew, J. S., Carlin, C. R., Carmignac, V., Carneiro, L. A. M., Carra, S., Caruso, R. A., Casari, G., Casas, C., Castino, R., Cebollero, E., Cecconi, F., Celli, J., Chaachouay, H., Chae, H. J., Chai, C. Y., Chan, D. C., Chan, E. Y., Chang, R. C. C., Che, C. M., Chen, C. C., Chen, G. C., Chen, G. Q., Chen, M., Chen, Q., Chen, S. S. L., Chen, W., Chen, X., Chen, X., Chen, X., Chen, Y. G., Chen, Y., Chen, Y., Chen, Y. J., Chen, Z., Cheng, A., Cheng, C. H. K., Cheng, Y., Cheong, H., Cheong, J. H., Cherry, S., Chess-Williams, R., Cheung, Z. H., Chevet, E., Chiang, H. L., Chiarelli, R., Chiba, T., Chin, L. S., Chiou, S. H., Chisari, F. V., Cho, C. H., Cho, D. H., Choi, A. M. K., Choi, D., Choi, K. S., Choi, M. E., Chouaib, S., Choubey, D., Choubey, V., Chu, C. T., Chuang, T. H., Chueh, S. H., Chun, T., Chwae, Y. J., Chye, M. L., Ciarcia, R., Ciriolo, M. R., Clague, M. J., Clark, R. S. B., Clarke, P. G. H., Clarke, R., Codogno, P., Coller, H. A., Colombo, M. I., Comincini, S., Condello, M., Condorelli, F., Cookson, M. R., Coombs, G. H., Coppens, I., Corbalan, R., Cossart, P., Costelli, P., Costes, S., Coto-Montes, A., Couve, E., Coxon, F. P., Cregg, J. M., Crespo, J. L., Cronjé, M. J., Cuervo, A. M., Cullen, J. J., Czaja, M. J., D'Amelio, M., Darfeuille-Michaud, A., Davids, L. M., Davies, F. E., De Felici, M., De Groot, J. F., De Haan, C. A. M., De Martino, L., De Milito, A., De Tata, V., Debnath, J., Degterev, A., Dehay, B., Delbridge, L. M. D., Demarchi, F., Deng, Y. Z., Dengjel, J., Dent, P., Denton, D., Deretic, V., Desai, S. D., Devenish, R. J., Di Gioacchino, M., Di Paolo, G., Di Pietro, C., Díaz-Araya, G., Díaz-Laviada, I., Diaz-Meco, M. T., Diaz-Nido, J., Dikic, I., Dinesh-Kumar, S. P., Ding, W. X., Distelhorst, C. W., Diwan, A., Djavaheri-Mergny, M., Dokudovskaya, S., Dong, Z., Dorsey, F. C., Dosenko, V., Dowling, J. J., Doxsey, S., Dreux, M., Drew, M. E., Duan, Q., Duchosal, M. A., Duff, K., Dugail, I., Durbeej, M., Duszenko, M., Edelstein, C. L., Edinger, A. L., Egea, G., Eichinger, L., Eissa, N. T., Ekmekcioglu, S., El-Deiry, W. S., Elazar, Z., Elgendy, M., Ellerby, L. M., Er Eng, K., Engelbrecht, A. M., Engelender, S., Erenpreisa, J., Escalante, R., Esclatine, A., Eskelinen, E. L., Espert, L., Espina, V., Fan, H., Fan, J., Fan, Q. W., Fan, Z., Fang, S., Fang, Y., Fanto, M., Fanzani, A., Farkas, T., Farré, J. C., Faure, M., Fechheimer, M., Feng, C. G., Feng, J., Feng, Q., Feng, Y., Fésüs, L., Feuer, R., Figueiredo-Pereira, M. E., Fimia, G. M., Fingar, D. C., Finkbeiner, S., Finkel, T., Finley, K. D., Fiorito, F., Fisher, E. A., Fisher, P. B., Flajolet, M., Florez-McClure, M. L., Florio, S., Fon, E. A., Fornai, F., Fortunato, F., Fotedar, R., Fowler, D. H., Fox, H. S., Franco, R., Frankel, L. B., Fransen, M., Fuentes, J. M., Fueyo, J., Fujii, J., Fujisaki, K., Fujita, E., Fukuda, M., Furukawa, R. H., Gaestel, M., Gailly, P., Gajewska, M., Galliot, B., Galy, V., Ganesh, S., Ganetzky, B., Ganley, I. G., Gao, F. B., Gao, G. F., Gao, J., Garcia, L., Garcia-Manero, G., Garcia-Marcos, M., Garmyn, M., Gartel, A. L., Gatti, E., Gautel, M., Gawriluk, T. R., Gegg, M. E., Geng, J., Germain, M., Gestwicki, J. E., Gewirtz, D. A., Ghavami, S., Ghosh, P., Giammarioli, A. M., Giatromanolaki, A. N., Gibson, S. B., Gilkerson, R. W., Ginger, M. L., Ginsberg, H. N., Golab, J., Goligorsky, M. S., Golstein, P., Gomez-Manzano, C., Goncu, E., Gongora, C., Gonzalez, C. D., Gonzalez, R., González-Estévez, C., González-Polo, R. A., Gonzalez-Rey, E., Gorbunov, N. V., Gorski, S., Goruppi, S., Gottlieb, R. A., Gozuacik, D., Granato, G. E., Grant, G. D., Green, K. N., Gregorc, A., Gros, F., Grose, C., Grunt, T. W., Gual, P., Guan, J. L., Guan, K. L., Guichard, S. M., Gukovskaya, A. S., Gukovsky, I., Gunst, J., Gustafsson, A. B., Halayko, A. J., Hale, A. N., Halonen, S. K., Hamasaki, M., Han, F., Han, T., Hancock, M. K., Hansen, M., Harada, H., Harada, M., Hardt, S. E., Harper, J. W., Harris, A. L., Harris, J., Harris, S. D., Hashimoto, M., Haspel, J. A., Hayashi, S. I., Hazelhurst, L. A., He, C., He, Y. W., Hébert, M. J., Heidenreich, K. A., Helfrich, M. H., Helgason, G. V., Henske, E. P., Herman, B., Herman, P. K., Hetz, C., Hilfiker, S., Hill, J. A., Hocking, L. J., Hofman, P., Hofmann, T. G., Höhfeld, J., Holyoake, T. L., Hong, M. H., Hood, D. A., Hotamisligil, G. S., Houwerzijl, E. J., Høyer-Hansen, M., Hu, B., Hu, C. A. A., Hu, H. M., Hua, Y., Huang, C., Huang, J., Huang, S., Huang, W. P., Huber, T. B., Huh, W. K., Hung, T. H., Hupp, T. R., Hur, G. M., Hurley, J. B., Hussain, S. N. A., Hussey, P. J., Hwang, J. J., Hwang, S., Ichihara, A., Ilkhanizadeh, S., Inoki, K., Into, T., Iovane, V., Iovanna, J. L., Ip, N. Y., Isaka, Y., Ishida, H., Isidoro, C., Isobe, K. I., Iwasaki, A., Izquierdo, M., Izumi, Y., Jaakkola, P. M., Jäättelä, M., Jackson, G. R., Jackson, W. T., Janji, B., Jendrach, M., Jeon, J. H., Jeung, E. B., Jiang, H., Jiang, H., Jiang, J. X., Jiang, M., Jiang, Q., Jiang, X., Jiménez, A., Jin, M., Jin, S., Joe, C. O., Johansen, T., Johnson, D. E., Johnson, G. V. W., Jones, N. L., Joseph, B., Joseph, S. K., Joubert, A. M., Juhász, G., Juillerat-Jeanneret, L., Jung, C. H., Jung, Y. K., Kaarniranta, K., Kaasik, A., Kabuta, T., Kadowaki, M., Kagedal, K., Kamada, Y., Kaminskyy, V. O., Kampinga, H. H., Kanamori, H., Kang, C., Kang, K. B., Il Kang, K., Kang, R., Kang, Y. A., Kanki, T., Kanneganti, T. D., Kanno, H., Kanthasamy, A. G., Kanthasamy, A., Karantza, V., Kaushal, G. P., Kaushik, S., Kawazoe, Y., Ke, P. Y., Kehrl, J. H., Kelekar, A., Kerkhoff, C., Kessel, D. H., Khalil, H., Kiel, J. A. K. W., Kiger, A. A., Kihara, A., Kim, D. R., Kim, D. H., Kim, D. H., Kim, E. K., Kim, H. R., Kim, J. S., Kim, J. H., Kim, J. C., Kim, J. K., Kim, P. K., Kim, S. W., Kim, Y. S., Kim, Y., Kimchi, A., Kimmelman, A. C., King, J. S., Kinsella, T. J., Kirkin, V., Kirshenbaum, L. A., Kitamoto, K., Kitazato, K., Klein, L., Klimecki, W. T., Klucken, J., Knecht, E., Ko, B. C. B., Koch, J. C., Koga, H., Koh, J. Y., Koh, Y. H., Koike, M., Komatsu, M., Kominami, E., Kong, H. J., Kong, W. J., Korolchuk, V. I., Kotake, Y., Koukourakis, M. I., Kouri Flores, J. B., Kovács, A. L., Kraft, C., Krainc, D., Krämer, H., Kretz-Remy, C., Krichevsky, A. M., Kroemer, G., Krüger, R., Krut, O., Ktistakis, N. T., Kuan, C. Y., Kucharczyk, R., Kumar, A., Kumar, R., Kumar, S., Kundu, M., Kung, H. J., Kurz, T., Kwon, H. J., La Spada, A. R., Lafont, F., Lamark, T., Landry, J., Lane, J. D., Lapaquette, P., Laporte, J. F., László, L., Lavandero, S., Lavoie, J. N., Layfield, R., Lazo, P. A., Le, W., Le Cam, L., Ledbetter, D. J., Lee, A. J. X., Lee, B. W., Lee, G. M., Lee, J., Lee, J. H., Lee, M., Lee, M. S., Lee, S. H., Leeuwenburgh, C., Legembre, P., Legouis, R., Lehmann, M., Lei, H. Y., Lei, Q. Y., Leib, D. A., Leiro, J., Lemasters, J. J., Lemoine, A., Lesniak, M. S., Lev, D., Levenson, V. V., Levine, B., Levy, E., Li, F., Li, J. L., Li, L., Li, S., Li, W., Li, X. J., Li, Y. B., Li, Y. P., Liang, C., Liang, Q., Liao, Y. F., Liberski, P. P., Lieberman, A., Lim, H. J., Lim, K. L., Lim, K., Lin, C. F., Lin, F. C., Lin, J., Lin, J. D., Lin, K., Lin, W. W., Lin, W. C., Lin, Y. L., Linden, R., Lingor, P., Lippincott-Schwartz, J., Lisanti, M. P., Liton, P. B., Liu, B., Liu, C. F., Liu, K., Liu, L., Liu, Q. A., Liu, W., Liu, Y. C., Liu, Y., Lockshin, R. A., Lok, C. N., Lonial, S., Loos, B., Lopez-Berestein, G., López-Otín, C., Lossi, L., Lotze, M. T., Lõw, P., Lu, B., Lu, B., Lu, B., Lu, Z., Luciano, F., Lukacs, N. W., Lund, A. H., Lynch-Day, M. A., Ma, Y., Macian, F., MacKeigan, J. P., Macleod, K. F., Madeo, F., Maiuri, L., Maiuri, M. C., Malagoli, D., Malicdan, M. C. V., Malorni, W., Man, N., Mandelkow, E. M., Manon, S., Manov, I., Mao, K., Mao, X., Mao, Z., Marambaud, P., Marazziti, D., Marcel, Y. L., Marchbank, K., Marchetti, P., Marciniak, S. J., Marcondes, M., Mardi, M., Marfe, G., Mariño, G., Markaki, M., Marten, M. R., Martin, S. J., Martinand-Mari, C., Martinet, W., Martinez-Vicente, M., Masini, M., Matarrese, P., Matsuo, S., Matteoni, R., Mayer, A., Mazure, N. M., McConkey, D. J., McConnell, M. J., McDermott, C., McDonald, C., McInerney, G. M., McKenna, S. L., McLaughlin, B., McLean, P. J., McMaster, C. R., McQuibban, G. A., Meijer, A. J., Meisler, M. H., Meléndez, A., Melia, T. J., Melino, G., Mena, M. A., Menendez, J. A., Menna-Barreto, R. F. S., Menon, M. B., Menzies, F. M., Mercer, C. A., Merighi, A., Merry, D. E., Meschini, S., Meyer, C. G., Meyer, T. F., Miao, C. Y., Miao, J. Y., Michels, P. A. M., Michiels, C., Mijaljica, D., Milojkovic, A., Minucci, S., Miracco, C., Miranti, C. K., Mitroulis, I., Miyazawa, K., Mizushima, N., Mograbi, B., Mohseni, S., Molero, X., Mollereau, B., Mollinedo, F., Momoi, T., Monastyrska, I., Monick, M. M., Monteiro, M. J., Moore, M. N., Mora, R., Moreau, K., Moreira, P. I., Moriyasu, Y., Moscat, J., Mostowy, S., Mottram, J. C., Motyl, T., Moussa, C. E. H., Müller, S., Muller, S., Münger, K., Münz, C., Murphy, L. O., Murphy, M. E., Musarò, A., Mysorekar, I., Nagata, E., Nagata, K., Nahimana, A., Nair, U., Nakagawa, T., Nakahira, K., Nakano, H., Nakatogawa, H., Nanjundan, M., Naqvi, N. I., Narendra, D. P., Narita, M., Navarro, M., Nawrocki, S. T., Nazarko, T. Y., Nemchenko, A., Netea, M. G., Neufeld, T. P., Ney, P. A., Nezis, I. P., Nguyen, H. P., Nie, D., Nishino, I., Nislow, C., Nixon, R. A., Noda, T., Noegel, A. A., Nogalska, A., Noguchi, S., Notterpek, L., Novak, I., Nozaki, T., Nukina, N., Nürnberger, T., Nyfeler, B., Obara, K., Oberley, T. D., Oddo, S., Ogawa, M., Ohashi, T., Okamoto, K., Oleinick, N. L., Oliver, F. J., Olsen, L. J., Olsson, S., Opota, O., Osborne, T. F., Ostrander, G. K., Otsu, K., Ou, J. H. J., Ouimet, M., Overholtzer, M., Ozpolat, B., Paganetti, P., Pagnini, U., Pallet, N., Palmer, G. E., Palumbo, C., Pan, T., Panaretakis, T., Pandey, U. B., Papackova, Z., Papassideri, I., Paris, I., Park, J., Park, O. K., Parys, J. B., Parzych, K. R., Patschan, S., Patterson, C., Pattingre, S., Pawelek, J. M., Peng, J., Perlmutter, D. H., Perrotta, I., Perry, G., Pervaiz, S., Peter, M., Peters, G. J., Petersen, M., Petrovski, G., Phang, J. M., Piacentini, M., Pierre, P., Pierrefite-Carle, V., Pierron, G., Pinkas-Kramarski, R., Piras, A., Piri, N., Platanias, L. C., Pöggeler, S., Poirot, M., Poletti, A., Poüs, C., Pozuelo-Rubio, M., Prætorius-Ibba, M., Prasad, A., Prescott, M., Priault, M., Produit-Zengaffinen, N., Progulske-Fox, A., Proikas-Cezanne, T., Przedborski, S., Przyklenk, K., Puertollano, R., Puyal, J., Qian, S. B., Qin, L., Qin, Z. H., Quaggin, S. E., Raben, N., Rabinowich, H., Rabkin, S. W., Rahman, I., Rami, A., Ramm, G., Randall, G., Randow, F., Rao, V. A., Rathmell, J. C., Ravikumar, B., Ray, S. K., Reed, B. H., Reed, J. C., Reggiori, F., Régnier-Vigouroux, A., Reichert, A. S., Reiners, J. J., Reiter, R. J., Ren, J., Revuelta, J. L., Rhodes, C. J., Ritis, K., Rizzo, E., Robbins, J., Roberge, M., Roca, H., Roccheri, M. C., Rocchi, S., Rodemann, H. P., De Córdoba, S. R., Rohrer, B., Roninson, I. B., Rosen, K., Rost-Roszkowska, M. M., Rouis, M., Rouschop, K. M. A., Rovetta, F., Rubin, B. P., Rubinsztein, D. C., Ruckdeschel, K., Rucker, E. B., Rudich, A., Rudolf, E., Ruiz-Opazo, N., Russo, R., Rusten, T. E., Ryan, K. M., Ryter, S. W., Sabatini, D. M., Sadoshima, J., Saha, T., Saitoh, T., Sakagami, H., Sakai, Y., Salekdeh, G. H., Salomoni, P., Salvaterra, P. M., Salvesen, G., Salvioli, R., Sanchez, A. M. J., Sánchez-Alcázar, J. A., Sánchez-Prieto, R., Sandri, M., Sankar, U., Sansanwal, P., Santambrogio, L., Saran, S., Sarkar, S., Sarwal, M., Sasakawa, C., Sasnauskiene, A., Sass, M., Sato, K., Sato, M., Schapira, A. H. V., Scharl, M., Schätzl, H. M., Scheper, W., Schiaffino, S., Schneider, C., Schneider, M. E., Schneider-Stock, R., Schoenlein, P. V., Schorderet, D. F., Schüller, C., Schwartz, G. K., Scorrano, L., Sealy, L., Seglen, P. O., Segura-Aguilar, J., Seiliez, I., Seleverstov, O., Sell, C., Seo, J. B., Separovic, D., Setaluri, V., Setoguchi, T., Settembre, C., Shacka, J. J., Shanmugam, M., Shapiro, I. M., Shaulian, E., Shaw, R. J., Shelhamer, J. H., Shen, H. M., Shen, W. C., Sheng, Z. H., Shi, Y., Shibuya, K., Shidoji, Y., Shieh, J. J., Shih, C. M., Shimada, Y., Shimizu, S., Shintani, T., Shirihai, O. S., Shore, G. C., Sibirny, A. A., Sidhu, S. B., Sikorska, B., Silva-Zacarin, E. C. M., Simmons, A., Simon, A. K., Simon, H. U., Simone, C., Simonsen, A., Sinclair, D. A., Singh, R., Sinha, D., Sinicrope, F. A., Sirko, A., Siu, P. M., Sivridis, E., Skop, V., Skulachev, V. P., Slack, R. S., Smaili, S. S., Smith, D. R., Soengas, M. S., Soldati, T., Song, X., Sood, A. K., Soong, T. W., Sotgia, F., Spector, S. A., Spies, C. D., Springer, W., Srinivasula, S. M., Stefanis, L., Steffan, J. S., Stendel, R., Stenmark, H., Stephanou, A., Stern, S. T., Sternberg, C., Stork, B., Strålfors, P., Subauste, C. S., Sui, X., Sulzer, D., Sun, J., Sun, S. Y., Sun, Z. J., Sung, J. J. Y., Suzuki, K., Suzuki, T., Swanson, M. S., Swanton, C., Sweeney, S. T., Sy, L. K., Szabadkai, G., Tabas, I., Taegtmeyer, H., Tafani, M., Takács-Vellai, K., Takano, Y., Takegawa, K., Takemura, G., Takeshita, F., Talbot, N. J., Tan, K. S. W., Tanaka, K., Tanaka, K., Tang, D., Tang, D., Tanida, I., Tannous, B. A., Tavernarakis, N., Taylor, G. S., Taylor, G. A., Taylor, J. P., Terada, A. S., Terman, A., Tettamanti, G., Thevissen, K., Thompson, C. B., Thorburn, A., Thumm, M., Tian, F., Tian, Y., Tocchini-Valentini, G., Tolkovsky, A. M., Tomino, Y., Tönges, L., Tooze, S. A., Tournier, C., Tower, J., Towns, R., Trajkovic, V., Travassos, L. H., Tsai, T. F., Tschan, M. P., Tsubata, T., Tsung, A., Turk, B., Turner, L. S., Tyagi, S. C., Uchiyama, Y., Ueno, T., Umekawa, M., Umemiya-Shirafuji, R., Unni, V. K., Vaccaro, M. I., Valente, E. M., Van Den Berghe, G., Van Der Klei, I. J., Van Doorn, W. G., Van Dyk, L. F., Van Egmond, M., Van Grunsven, L. A., Vandenabeele, P., Vandenberghe, W. P., Vanhorebeek, I., Vaquero, E. C., Velasco, G., Vellai, T., Vicencio, J. M., Vierstra, R. D., Vila, M., Vindis, C., Viola, G., Viscomi, M. T., Voitsekhovskaja, O. V., Von Haefen, C., Votruba, M., Wada, K., Wade-Martins, R., Walker, C. L., Walsh, C. M., Walter, J., Wan, X. B., Wang, A., Wang, C., Wang, D., Wang, F., Wang, F., Wang, G., Wang, H., Wang, H. G., Wang, H. D., Wang, J., Wang, K., Wang, M., Wang, R. C., Wang, X., Wang, X., Wang, Y. J., Wang, Y., Wang, Z., Wang, Z. C., Wang, Z., Wansink, D. G., Ward, D. M., Watada, H., Waters, S. L., Webster, P., Wei, L., Weihl, C. C., Weiss, W. A., Welford, S. M., Wen, L. P., Whitehouse, C. A., Whitton, J. L., Whitworth, A. J., Wileman, T., Wiley, J. W., Wilkinson, S., Willbold, D., Williams, R. L., Williamson, P. R., Wouters, B. G., Wu, C., Wu, D. C., Wu, W. K. K., Wyttenbach, A., Xavier, R. J., Xi, Z., Xia, P., Xiao, G., Xie, Z., Xie, Z., Xu, D. Z., Xu, J., Xu, L., Xu, X., Yamamoto, A., Yamamoto, A., Yamashina, S., Yamashita, M., Yan, X., Yanagida, M., Yang, D. S., Yang, E., Yang, J. M., Yang, S. Y., Yang, W., Yang, W. Y., Yang, Z., Yao, M. C., Yao, T. P., Yeganeh, B., Yen, W. L., Yin, J. J., Yin, X. M., Yoo, O. J., Yoon, G., Yoon, S. Y., Yorimitsu, T., Yoshikawa, Y., Yoshimori, T., Yoshimoto, K., You, H. J., Youle, R. J., Younes, A., Yu, L., Yu, L., Yu, S. W., Yu, W. H., Yuan, Z. M., Yue, Z., Yun, C. H., Yuzaki, M., Zabirnyk, O., Silva-Zacarin, E., David Zacks, E., Zacksenhaus, L., Zaffaroni, N., Zakeri, Z., Zeh, H. J., Zeitlin, S. O., Zhang, H., Zhang, H. L., Zhang, J., Zhang, J. P., Zhang, L., Zhang, L., Zhang, M. Y., Zhang, X. D., Zhao, M., Zhao, Y. F., Zhao, Y., Zhao, Z. J., Zheng, X., Zhivotovsky, B., Zhong, Q., Zhou, C. Z., Zhu, C., Zhu, W. G., Zhu, X. F., Zhu, X., Zhu, Y., Zoladek, T., Zong, W. X., Zorzano, A., Zschocke, J. & Zuckerbraun, B., Apr 1 2012, In : Autophagy. 8, 4, p. 445-544 100 p.

Research output: Contribution to journalReview article

2447 Scopus citations
2011

A knockout of the caspase 2 gene produces increased resistance of the nigrostriatal dopaminergic pathway to MPTP-induced toxicity

Tiwari, M., Herman, B. & Morgan, W. W., Jun 1 2011, In : Experimental Neurology. 229, 2, p. 421-428 8 p.

Research output: Contribution to journalArticle

3 Scopus citations

Loss of caspase-2-dependent apoptosis induces autophagy after mitochondrial oxidative stress in primary cultures of young adult cortical neurons

Tiwari, M., Lopez-Cruzan, M., Morgan, W. W. & Herman, B., Mar 11 2011, In : Journal of Biological Chemistry. 286, 10, p. 8493-8506 14 p.

Research output: Contribution to journalArticle

53 Scopus citations
2009

FLIM microscopy with a streak camera: Monitoring metabolic processes in living cells and tissues

Krishnan Ramanujan, V., Jo, J. A., Ranjan, R. & Herman, B. A., Jan 1 2009, Flim Microscopy in Biology and Medicine. CRC Press, p. 189-209 21 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2008
11 Scopus citations

Nonlinear scaling analysis of glucose metabolism in normal and cancer cells

Ramanujan, V. K. & Herman, B. A., Dec 1 2008, In : Journal of biomedical optics. 13, 3, 031219.

Research output: Contribution to journalArticle

9 Scopus citations

Spatially resolved fluorescence lifetime mapping of enzyme kinetics in living cells

Ramanujan, V. K., Jo, J. A., Cantu, G. & Herman, B. A., Jun 1 2008, In : Journal of Microscopy. 230, 3, p. 329-338 10 p.

Research output: Contribution to journalArticle

22 Scopus citations
2007

Aging process modulates nonlinear dynamics in liver cell metabolism

Ramanujan, V. K. & Herman, B. A., Jun 29 2007, In : Journal of Biological Chemistry. 282, 26, p. 19217-19226 10 p.

Research output: Contribution to journalArticle

16 Scopus citations

Caspase-2 deficiency enhances aging-related traits in mice

Zhang, Y., Padalecki, S. S., Chaudhuri, A. R., De Waal, E., Goins, B. A., Grubbs, B., Ikeno, Y., Richardson, A., Mundy, G. R. & Herman, B., Feb 1 2007, In : Mechanisms of Ageing and Development. 128, 2, p. 213-221 9 p.

Research output: Contribution to journalArticle

60 Scopus citations

Fluorescence lifetime contrast in small animal imaging

Ramanujan, V. K., Bandyopadhyay, A., Sun, L. Z. & Herman, B. A., Apr 30 2007, Genetically Engineered and Optical Probes for Biomedical Applications IV. 644911. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; vol. 6449).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Mitochondrial dysfunction modulates nonlinear dynamics in liver cell metabolism

Ramanujan, V. K. & Herman, B. A., Aug 31 2007, Complex Dynamics and Fluctuations in Biomedical Photonics IV. 64360G. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; vol. 6436).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2006

ARC protects rat cardiomyocytes against oxidative stress through inhibition of caspase-2 mediated mitochondrial pathway

Zhang, Y. Q. & Herman, B., Oct 1 2006, In : Journal of Cellular Biochemistry. 99, 2, p. 575-588 14 p.

Research output: Contribution to journalArticle

28 Scopus citations

Scaling behavior in mitochondrial redox fluctuations

Ramanujan, V. K., Biener, G. & Herman, B. A., May 2006, In : Biophysical journal. 90, 10, p. L70-L72

Research output: Contribution to journalArticle

17 Scopus citations

Spatio-temporal kinetics of growth hormone receptor signaling in single cells using FRET microscopy

Biener-Ramanujan, E., Ramanujan, V. K., Herman, B. & Gertler, A., Aug 1 2006, In : Growth Hormone and IGF Research. 16, 4, p. 247-257 11 p.

Research output: Contribution to journalArticle

11 Scopus citations

Spectral kinetics ratiometry: A simple approach for real-time monitoring of fluorophore distributions in living cells

Ramanujan, V. K., Biener-Ramanujan, E., Armmer, K., Centonze, V. E. & Herman, B. A., Aug 1 2006, In : Cytometry Part A. 69, 8, p. 912-919 8 p.

Research output: Contribution to journalArticle

8 Scopus citations

Time-resolved nanoscale imaging of biomolecules in living cells and tissues: Prospects for small animal imaging

Krishnan Ramanujan, V., Mireles, J. R. & Herman, B. A., May 8 2006, Proceedings of SPIE - The International Society for Optical Engineering. 608901. (Proceedings of SPIE - The International Society for Optical Engineering; vol. 6089).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2005

Fluorescence resonance energy transfer (FRET) microscopy in living cells as a novel tool for the study of cytokine action

Gertler, A., Biener, E., Ramanujan, K. V., Djiane, J. & Herman, B., Sep 27 2005, In : Journal of Dairy Research. 72, SPEC. ISS., p. 14-19 6 p.

Research output: Contribution to journalReview article

14 Scopus citations

Identification of the hydrophobia strand in the A-B loop of leptin as major binding site III: Implications for large-scale preparation of potent recombinant human and ovine leptin antagonists

Niv-Spector, L., Gonen-Berger, D., Gourdou, I., Biener, E., Gussakovsky, E. E., Benomar, Y., Ramanujan, K. V., Taouis, M., Herman, B., Callebaut, I., Djiane, J. & Gertler, A., Oct 15 2005, In : Biochemical Journal. 391, 2, p. 221-230 10 p.

Research output: Contribution to journalArticle

80 Scopus citations

Monitoring mitochondrial caspase-2 activity in intact cells by streak camera based fluorescence lifetime imaging microscopy

Herman, B. A., Zhang, J. H., Ramanujan, V. K., Lopez-Cruzan, M., Medina, S. & Centonze, V. E., Aug 25 2005, In : Microscopy and Microanalysis. 11, SUPPL. 2, p. 8-9 2 p.

Research output: Contribution to journalArticle

1 Scopus citations

Multiphoton fluorescence lifetime contrast in deep tissue imaging: Prospects in redox imaging and disease diagnosis

Ramanujan, V. K., Zhang, J. H., Biener, E. & Herman, B., Sep 1 2005, In : Journal of biomedical optics. 10, 5, 051407.

Research output: Contribution to journalArticle

46 Scopus citations

Quantitative FRET imaging of leptin receptor oligomerization kinetics in single cells

Ramanujan, V. K., Biener, E., Charlier, M., Daniel, N., Eisenberg, A., Herman, B., Djiane, J. & Gertler, A., Aug 25 2005, In : Microscopy and Microanalysis. 11, SUPPL. 2, p. 10-11 2 p.

Research output: Contribution to journalArticle

1 Scopus citations

Quantitative FRET imaging of leptin receptor oligomerization kinetics in single cells

Biener, E., Charlier, M., Ramanujan, V. K., Daniel, N., Eisenberg, A., Bjørbaek, C., Herman, B., Gertler, A. & Djiane, J., Dec 1 2005, In : Biology of the Cell. 97, 12, p. 905-919 15 p.

Research output: Contribution to journalArticle

33 Scopus citations

Streak Fluorescence Lifetime Imaging Microscopy. A Novel Technology for Quantitative FRET Imaging

Ramanujan, V. K., Zhang, J. H., Centonze, V. E. & Herman, B., Dec 1 2005, Molecular Imaging. Elsevier Inc., p. 227-238 12 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Scopus citations
2004

Detection of mitochondrial caspase activity in real time in situ in live cells

Zhang, Y., Haskins, C., Lopez-Cruzan, M., Zhang, J., Centonze, V. E. & Herman, B., Aug 1 2004, In : Microscopy and Microanalysis. 10, 4, p. 442-448 7 p.

Research output: Contribution to journalArticle

8 Scopus citations

Discrimination of depolarized from polarized mitochondria by confocal fluorescence resonance energy transfer

Elmore, S. P., Nishimura, Y., Qian, T., Herman, B. & Lemasters, J. J., Feb 15 2004, In : Archives of Biochemistry and Biophysics. 422, 2, p. 145-152 8 p.

Research output: Contribution to journalArticle

36 Scopus citations

Microscopic analysis of fluorescence resonance energy transfer (FRET).

Herman, B., Krishnan, R. V. & Centonze, V. E., Aug 3 2004, In : Methods in molecular biology (Clifton, N.J.). 261, p. 351-370 20 p.

Research output: Contribution to journalReview article

28 Scopus citations

Multiphoton FLIM: A reliable FRET detection tool in cell biological applications

Krishnan, R. V., Biener, E., Centonze, V. E., Gertler, A. & Herman, B., Oct 28 2004, In : Proceedings of SPIE - The International Society for Optical Engineering. 5323, p. 63-70 8 p.

Research output: Contribution to journalConference article

1 Scopus citations

Oxidative stress-induced apoptosis is associated with alterations in mitochondrial caspase activity and Bcl-2-dependent alterations in mitochondrial pH (pHm)

Takahashi, A., Masuda, A., Sun, M., Centonze, V. E. & Herman, B., Feb 15 2004, In : Brain Research Bulletin. 62, 6, p. 497-504 8 p.

Research output: Contribution to journalArticle

151 Scopus citations

Transactivation of erbB2 by short and long isoforms of leptin receptors

Eisenberg, A., Biener, E., Charlier, M., Krishnan, R. V., Djiane, J., Herman, B. & Gertler, A., May 7 2004, In : FEBS Letters. 565, 1-3, p. 139-142 4 p.

Research output: Contribution to journalArticle

39 Scopus citations

Transgenic mice overexpressing glutathione peroxidase 4 are protected against oxidative stress-induced apoptosis

Ran, Q., Liang, H., Gu, M., Qi, W., Walter, C. A., Roberts, L. J., Herman, B., Richardson, A. & Van Remmen, H., Dec 31 2004, In : Journal of Biological Chemistry. 279, 53, p. 55137-55146 10 p.

Research output: Contribution to journalArticle

157 Scopus citations
2003

Caspases, apoptosis and aging

Zhang, J. H., Zhang, Y. & Herman, B., Oct 2003, In : Ageing Research Reviews. 2, 4, p. 357-366 10 p.

Research output: Contribution to journalReview article

81 Scopus citations

Development of a multiphoton fluorescence lifetime imaging microscopy system using a streak camera

Krishnan, R. V., Saitoh, H., Terada, H., Centonze, V. E. & Herman, B., May 1 2003, In : Review of Scientific Instruments. 74, 5, p. 2714-2721 8 p.

Research output: Contribution to journalArticle

93 Scopus citations

Fluorescence resonance energy transfer imaging microscopy

Centonze, V. E., Sun, M., Masuda, A., Gerritsen, H. & Herman, B., Jan 1 2003, In : Methods in enzymology. 360, p. 542-560 19 p.

Research output: Contribution to journalArticle

38 Scopus citations

FRET and FLIM microscopy in the study of the role of oxidative stress and apoptosis in aging

Zhang, Y., Zhang, J., Masuda, A., Lopez-Cruzan, M., Centonze, V., Krishnan, R. V. & Herman, B., Sep 4 2003, In : Microscopy and Microanalysis. 9, SUPPL. 2, p. 226-227 2 p.

Research output: Contribution to journalArticle

2 Scopus citations

Multiphoton fluorescence lifetime imaging microscopy (FLIM) using a streak camera

Krishnan, R. V., Saitoh, H., Terada, H., Centonze, V. E. & Herman, B., Sep 29 2003, In : Proceedings of SPIE - The International Society for Optical Engineering. 4963, p. 165-174 10 p.

Research output: Contribution to journalConference article

36 Scopus citations

Probing subtle fluorescence dynamics in cellular proteins by streak camera based fluorescence lifetime imaging microscopy

Krishnan, R. V., Biener, E., Zhang, J. H., Heckel, R. & Herman, B., Dec 1 2003, In : Applied Physics Letters. 83, 22, p. 4658-4660 3 p.

Research output: Contribution to journalArticle

25 Scopus citations

Quantitative imaging of protein-protein interactions by multiphoton fluorescence lifetime imaging microscopy using a streak camera

Krishnan, R. V., Masuda, A., Centonze, V. E. & Herman, B., Jul 1 2003, In : Journal of biomedical optics. 8, 3, p. 362-367 6 p.

Research output: Contribution to journalReview article

64 Scopus citations
2002

Age-associated increases in the activity of multiple caspases in Fisher 344 rat organs

Zhang, Y., Chong, E. & Herman, B., Jun 1 2002, In : Experimental Gerontology. 37, 6, p. 777-789 13 p.

Research output: Contribution to journalArticle

63 Scopus citations

Ageing and apoptosis

Zhang, Y. & Herman, B., Jan 1 2002, In : Mechanisms of Ageing and Development. 123, 4, p. 245-260 16 p.

Research output: Contribution to journalReview article

123 Scopus citations

Apoptosis and successful aging

Zhang, Y. & Herman, B., Mar 31 2002, In : Mechanisms of Ageing and Development. 123, 6, p. 563-565 3 p.

Research output: Contribution to journalEditorial

20 Scopus citations

Fluorescence microscopy.

Herman, B., Feb 1 2002, In : Current protocols in cell biology / editorial board, Juan S. Bonifacino ... [et al.]. Chapter 4

Research output: Contribution to journalReview article

1 Scopus citations

Fluorescence microscopy.

Herman, B., May 2002, In : Current protocols in immunology / edited by John E. Coligan ... [et al.]. Chapter 21, p. Unit 21.2

Research output: Contribution to journalArticle