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Brent Koehn

20022019
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Graft vs Host Disease Medicine & Life Sciences
T-Lymphocytes Medicine & Life Sciences
Grafts Chemical Compounds
T-cells Chemical Compounds
Inflammasomes Medicine & Life Sciences
Myeloid Cells Medicine & Life Sciences
Transplantation Medicine & Life Sciences
Regulatory T-Lymphocytes Medicine & Life Sciences

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Projects 2010 2011

Tolerogenic Programming of CD8 T cells for Tumor Escape

Koehn, B.

AMERICAN CANCER SOCIETY, INC.

4/1/10 → 6/30/11

Project: Research project

Tumor Escape
T-Lymphocytes

Research Output 2002 2019

1 Citation (Scopus)

Danger-associated extracellular ATP counters MDSC therapeutic efficacy in acute GVHD

Koehn, B. H., Saha, A., McDonald-Hyman, C., Loschi, M., Thangavelu, G., Ma, L., Zaiken, M., Dysthe, J., Krepps, W., Panthera, J., Hippen, K., Jameson, S. C., Miller, J. S., Cooper, M. A., Farady, C. J., Iwawaki, T., Ting, J. P. Y., Serody, J. S., Murphy, W. J., Hill, G. R. & 5 others, Murray, P. J., Bronte, V., Munn, D. H., Zeiser, R. & Blazar, B. R., Nov 7 2019, In : Blood. 134, 19, p. 1670-1682 13 p.

Research output: Contribution to journal › Article

Inflammasomes
Graft vs Host Disease
Interleukin-1
Grafts
Adenosine Triphosphate
1 Citation (Scopus)

Dendritic Cell Expression of Retinal Aldehyde Dehydrogenase-2 Controls Graft-versus-Host Disease Lethality

Thangavelu, G., Lee, Y. C., Loschi, M., Melanie Schaechter, K., Feser, C. J., Koehn, B., Nowak, E. C., Zeiser, R., Serody, J. S., Murphy, W. J., Munn, D. H., Chambon, P., Noelle, R. J. & Blazar, B. R., May 1 2019, In : Journal of Immunology. 202, 9, p. 2795-2805 11 p.

Research output: Contribution to journal › Article

Retinal Dehydrogenase
Aldehyde Dehydrogenase
Graft vs Host Disease
Tretinoin
Dendritic Cells
25 Citations (Scopus)

Activation of p53 in Immature Myeloid Precursor Cells Controls Differentiation into Ly6c+CD103+ Monocytic Antigen-Presenting Cells in Tumors

Sharma, M. D., Rodriguez, P. C., Koehn, B. H., Baban, B., Cui, Y., Guo, G., Shimoda, M., Pacholczyk, R., Shi, H., Lee, E. J., Xu, H., Johnson, T. S., He, Y., Mergoub, T., Venable, C., Bronte, V., Wolchok, J. D., Blazar, B. R. & Munn, D. H., Jan 16 2018, In : Immunity. 48, 1, p. 91-106.e6

Research output: Contribution to journal › Article

Open Access
Antigen-Presenting Cells
Myeloid Cells
Immunotherapy
Cell Differentiation
Cross-Priming
4 Citations (Scopus)

The vimentin intermediate filament network restrains regulatory T cell suppression of graft-versus-host disease

McDonald-Hyman, C. S., Muller, J. T., Loschi, M., Thangavelu, G., Saha, A., Kumari, S., Reichenbach, D. K., Smith, M. J., Zhang, G., Koehn, B., Lin, J., Mitchell, J. S., Fife, B. T., Panoskaltsis-Mortari, A., Feser, C. J., Kirchmeier, A. K., Osborn, M. J., Hippen, K. L., Kelekar, A., Serody, J. S. & 6 others, Turka, L. A., Munn, D. H., Chi, H., Neubert, T. A., Dustin, M. L. & Blazar, B. R., Oct 1 2018, In : Journal of Clinical Investigation. 128, 10, p. 4604-4621 18 p.

Research output: Contribution to journal › Article

Open Access
Intermediate Filaments
Graft vs Host Disease
Vimentin
Regulatory T-Lymphocytes
Protein Kinase C
11 Citations (Scopus)

Role of myeloid-derived suppressor cells in allogeneic hematopoietic cell transplantation

Koehn, B. H. & Blazar, B. R., Aug 2017, In : Journal of Leukocyte Biology. 102, 2, p. 335-341 7 p.

Research output: Contribution to journal › Review article

Open Access
Cell Transplantation
Graft vs Host Disease
Hematopoietic Stem Cell Transplantation
Myeloid Cells
Inflammation