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Brent Koehn

20022019
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Graft vs Host Disease Medicine & Life Sciences
T-Lymphocytes Medicine & Life Sciences
Grafts Chemical Compounds
T-cells Chemical Compounds
Immunotherapy Medicine & Life Sciences
Myeloid Cells Medicine & Life Sciences
Inflammasomes Medicine & Life Sciences
Transplantation Medicine & Life Sciences

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Projects 2010 2011

Tolerogenic Programming of CD8 T cells for Tumor Escape

Koehn, B.

AMERICAN CANCER SOCIETY, INC.

4/1/10 → 6/30/11

Project: Research project

Tumor Escape
T-Lymphocytes

Research Output 2002 2019

Dendritic Cell Expression of Retinal Aldehyde Dehydrogenase-2 Controls Graft-versus-Host Disease Lethality

Thangavelu, G., Lee, Y. C., Loschi, M., Melanie Schaechter, K., Feser, C. J., Koehn, B., Nowak, E. C., Zeiser, R., Serody, J. S., Murphy, W. J., Munn, D. H., Chambon, P., Noelle, R. J. & Blazar, B. R., May 1 2019, In : Journal of Immunology. 202, 9, p. 2795-2805 11 p.

Research output: Contribution to journal › Article

Retinal Dehydrogenase
Aldehyde Dehydrogenase
Graft vs Host Disease
Tretinoin
Dendritic Cells
20 Citations (Scopus)

Activation of p53 in Immature Myeloid Precursor Cells Controls Differentiation into Ly6c+CD103+ Monocytic Antigen-Presenting Cells in Tumors

Sharma, M. D., Rodriguez, P. C., Koehn, B., Baban, B., Cui, Y., Guo, G., Shimoda, M., Pacholczyk, R., Shi, H., Lee, E. J., Xu, H., Johnson, T. S., He, Y., Mergoub, T., Venable, C., Bronte, V., Wolchok, J. D., Blazar, B. R. & Munn, D. H., Jan 16 2018, In : Immunity. 48, 1, p. 91-106.e6

Research output: Contribution to journal › Article

Antigen-Presenting Cells
Myeloid Cells
Immunotherapy
Cell Differentiation
Cross-Priming
1 Citation (Scopus)

The vimentin intermediate filament network restrains regulatory T cell suppression of graft-versus-host disease

McDonald-Hyman, C. S., Muller, J. T., Loschi, M., Thangavelu, G., Saha, A., Kumari, S., Reichenbach, D. K., Smith, M. J., Zhang, G., Koehn, B., Lin, J., Mitchell, J. S., Fife, B. T., Panoskaltsis-Mortari, A., Feser, C. J., Kirchmeier, A. K., Osborn, M. J., Hippen, K. L., Kelekar, A., Serody, J. S. & 6 others, Turka, L. A., Munn, D. H., Chi, H., Neubert, T. A., Dustin, M. L. & Blazar, B. R., Oct 1 2018, In : Journal of Clinical Investigation. 128, 10, p. 4604-4621 18 p.

Research output: Contribution to journal › Article

Intermediate Filaments
Graft vs Host Disease
Vimentin
Regulatory T-Lymphocytes
Protein Kinase C
8 Citations (Scopus)

Role of myeloid-derived suppressor cells in allogeneic hematopoietic cell transplantation

Koehn, B. & Blazar, B. R., Aug 1 2017, In : Journal of Leukocyte Biology. 102, 2, p. 335-341 7 p.

Research output: Contribution to journal › Review article

Cell Transplantation
Graft vs Host Disease
Hematopoietic Stem Cell Transplantation
Myeloid Cells
Inflammation
41 Citations (Scopus)

Peri-alloHCT IL-33 administration expands recipient T-regulatory cells that protect mice against acute GVHD

Matta, B. M., Reichenbach, D. K., Zhang, X., Mathews, L., Koehn, B., Dwyer, G. K., Lott, J. M., Uhl, F. M., Pfeifer, D., Feser, C. J., Smith, M. J., Liu, Q., Zeiser, R., Blazar, B. R. & Turnquist, H. R., Jul 21 2016, In : Blood. 128, 3, p. 427-439 13 p.

Research output: Contribution to journal › Article

Cell Transplantation
Graft vs Host Disease
Regulatory T-Lymphocytes
Grafts
Transplantation (surgical)