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Benjamin J Hackel

20042023
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  • 1 Similar Profiles
Fibronectins Medicine & Life Sciences
Scaffolds Chemical Compounds
Yeasts Medicine & Life Sciences
Libraries Medicine & Life Sciences
Yeast Chemical Compounds
Ligands Medicine & Life Sciences
Molecular imaging Engineering & Materials Science
Photoacoustic effect Chemical Compounds

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Projects 2013 2023

Engineering Synthetic Ligands with Potent Allosteric Inhibition of Tumornecrosis Factor Receptors

Hackel, B. J.

NIH NATL INST OF BIOMEDICAL IM

9/15/19 → 6/30/23

Project: Research project

Ligands

Protein engineered inhibitors of TNF Receptor activation: new therapeutics and new technology

Sachs, J. N. & Hackel, B. J.

NIH Nat'l Inst of Allergy & Infect Dis

2/1/19 → 1/31/21

Project: Research project

Tumor Necrosis Factor Receptors
Technology
Proteins
Therapeutics

Copolymer-based sarcolemma stabilization for protecting

Metzger, J. M., Bates, F. S. & Hackel, B. J.

NIH NIAMS NATL INST OF ARTHRIT

5/1/18 → 4/30/23

Project: Research project

Sarcolemma
Skeletal Muscle

Indirect Detection of Cell-Bound Biomarkers via Syntheti

Hackel, B. J.

AMERICAN CANCER SOCIETY, INC.

7/1/17 → 6/30/21

Project: Research project

Biomarkers

Engineering Gp2 as a small ligand scaffold

Hackel, B. J. & Patel, M. R.

NIH NATL INST OF BIOMEDICAL IM

7/1/17 → 3/31/21

Project: Research project

Scaffolds
Ligands

Research Output 2004 2020

  • 52 Article
  • 6 Conference contribution
  • 3 Chapter
  • 2 Review article

Ligand Engineering via Yeast Surface Display and Adherent Cell Panning

Stern, L. A., Lown, P. S. & Hackel, B. J., Jan 1 2020, In : Methods in molecular biology (Clifton, N.J.). 2070, p. 303-320 18 p.

Research output: Contribution to journal › Article

Yeasts
Ligands
Genotype
Phenotype
Antigens
1 Citation (Scopus)

Affibody-Indocyanine Green Based Contrast Agent for Photoacoustic and Fluorescence Molecular Imaging of B7-H3 Expression in Breast Cancer

Bam, R., Laffey, M., Nottberg, K., Lown, P. S., Hackel, B. J. & Wilson, K. E., Jun 19 2019, In : Bioconjugate Chemistry. 30, 6, p. 1677-1689 13 p.

Research output: Contribution to journal › Article

Molecular imaging
Molecular Imaging
Indocyanine Green
Photoacoustic effect
Optical Imaging

Biophysical characterization platform informs protein scaffold evolvability

Golinski, A. W., Holec, P. V., Mischler, K. M. & Hackel, B. J., Jan 1 2019, In : ACS Combinatorial Science.

Research output: Contribution to journal › Article

Open Access
Scaffolds
Proteins
Antibody Binding Sites
Molecular recognition
Fungal Proteins

Cardiac Muscle Membrane Stabilization in Myocardial Reperfusion Injury

Houang, E. M., Bartos, J. A., Hackel, B. J., Lodge, T. P., Yannopoulos, D., Bates, F. S. & Metzger, J. M., Apr 1 2019, In : JACC: Basic to Translational Science. 4, 2, p. 275-287 13 p.

Research output: Contribution to journal › Review article

Open Access
Myocardial Reperfusion Injury
Myocardium
Membranes
Muscles
Heart Diseases
2 Citations (Scopus)

Cellular-Based Selections Aid Yeast-Display Discovery of Genuine Cell-Binding Ligands: Targeting Oncology Vascular Biomarker CD276

Stern, L. A., Lown, P. S., Kobe, A. C., Abou-Elkacem, L., Willmann, J. K. & Hackel, B. J., Mar 11 2019, In : ACS Combinatorial Science. 21, 3, p. 207-222 16 p.

Research output: Contribution to journal › Article

Oncology
Biomarkers
Yeast
Display devices
Ligands