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Benjamin J Hackel

20042023
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Fingerprint The Fingerprint is created by mining the titles and abstracts of the person's research outputs and projects/funding awards to create an index of weighted terms from discipline-specific thesauri.

Fibronectins Medicine & Life Sciences
Scaffolds Chemical Compounds
Yeasts Medicine & Life Sciences
Libraries Medicine & Life Sciences
Yeast Chemical Compounds
Ligands Medicine & Life Sciences
Molecular imaging Engineering & Materials Science
Photoacoustic effect Chemical Compounds

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Projects 2013 2023

Engineering Synthetic Ligands with Potent Allosteric Inhibition of Tumornecrosis Factor Receptors

Hackel, B. J.

NIH NATL INST OF BIOMEDICAL IM

9/15/19 → 6/30/23

Project: Research project

Ligands

Protein engineered inhibitors of TNF Receptor activation: new therapeutics and new technology

Sachs, J. N. & Hackel, B. J.

NIH Nat'l Inst of Allergy & Infect Dis

2/1/19 → 1/31/21

Project: Research project

Tumor Necrosis Factor Receptors
Technology
Proteins
Therapeutics

Copolymer-based sarcolemma stabilization for protecting

Metzger, J. M., Bates, F. S. & Hackel, B. J.

NIH NIAMS NATL INST OF ARTHRIT

5/1/18 → 4/30/23

Project: Research project

Sarcolemma
Skeletal Muscle

Indirect Detection of Cell-Bound Biomarkers via Syntheti

Hackel, B. J.

AMERICAN CANCER SOCIETY, INC.

7/1/17 → 6/30/21

Project: Research project

Biomarkers

Engineering Gp2 as a small ligand scaffold

Hackel, B. J. & Patel, M. R.

NIH NATL INST OF BIOMEDICAL IM

7/1/17 → 3/31/21

Project: Research project

Scaffolds
Ligands

Research Output 2004 2020

  • 51 Article
  • 6 Conference contribution
  • 4 Chapter
  • 2 Review article

Ligand Engineering via Yeast Surface Display and Adherent Cell Panning

Stern, L. A., Lown, P. S. & Hackel, B. J., Jan 1 2020, Methods in Molecular Biology. Humana Press Inc., p. 303-320 18 p. (Methods in Molecular Biology; vol. 2070).

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Yeasts
Ligands
Genotype
Phenotype
Antigens
3 Citations (Scopus)

Affibody-Indocyanine Green Based Contrast Agent for Photoacoustic and Fluorescence Molecular Imaging of B7-H3 Expression in Breast Cancer

Bam, R., Laffey, M., Nottberg, K., Lown, P. S., Hackel, B. J. & Wilson, K. E., Jun 19 2019, In : Bioconjugate Chemistry. 30, 6, p. 1677-1689 13 p.

Research output: Contribution to journal › Article

Molecular imaging
Molecular Imaging
Indocyanine Green
Photoacoustic effect
Optical Imaging

Biophysical characterization platform informs protein scaffold evolvability

Golinski, A. W., Holec, P. V., Mischler, K. M. & Hackel, B. J., Jan 1 2019, In : ACS Combinatorial Science.

Research output: Contribution to journal › Article

Open Access
Scaffolds
Proteins
Antibody Binding Sites
Molecular recognition
Fungal Proteins
1 Citation (Scopus)

Cardiac Muscle Membrane Stabilization in Myocardial Reperfusion Injury

Houang, E. M., Bartos, J. A., Hackel, B. J., Lodge, T. P., Yannopoulos, D., Bates, F. S. & Metzger, J. M., Apr 1 2019, In : JACC: Basic to Translational Science. 4, 2, p. 275-287 13 p.

Research output: Contribution to journal › Review article

Open Access
Myocardial Reperfusion Injury
Myocardium
Membranes
Muscles
Heart Diseases
3 Citations (Scopus)

Cellular-Based Selections Aid Yeast-Display Discovery of Genuine Cell-Binding Ligands: Targeting Oncology Vascular Biomarker CD276

Stern, L. A., Lown, P. S., Kobe, A. C., Abou-Elkacem, L., Willmann, J. K. & Hackel, B. J., Mar 11 2019, In : ACS Combinatorial Science. 21, 3, p. 207-222 16 p.

Research output: Contribution to journal › Article

Oncology
Biomarkers
Yeast
Display devices
Ligands