Projects per year
Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 2 Zero Hunger
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SDG 3 Good Health and Well-being
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SDG 9 Industry, Innovation, and Infrastructure
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Collaborations and top research areas from the last five years
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Engineered cell specificity via avidity
Hackel, B. (PI) & Sarkar, C. (PI)
NIH NATIONAL INST OF BIOMEDICAL IM
5/1/26 → 2/28/30
Project: Research project
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Natural killer cell mediated targeting of IGF1R and IR-A in hormone receptor positive breast cancer
Hackel, B. (PI)
8/1/25 → 7/31/28
Project: Research project
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Human iPSC-Derived Chimeric Antigen Receptor Macrophages to Modulate Inflammation and Combat Tau-Induced Pathology
Crane, A. T. (PI), Hackel, B. (PI), Li, L. (PI), Liu, P. (PI), Sachs, J. N. (PI) & Webber, B. R. (PI)
NIH NATIONAL INSTITUTE ON AGING
1/15/25 → 12/31/26
Project: Research project
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Engineering Immune Engagers
Hackel, B. (PI) & Walsh, M. A. (CoI)
NATIONAL INSTITUTES OF HEALTH (NIH)
8/26/24 → 8/25/28
Project: Research project
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Engineering Protein Developability
Hackel, B. (PI) & Martiniani, S. (CoI)
NIH NIGMS NATL INST OF GENERAL
9/1/22 → 5/31/27
Project: Research project
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Engineered B7-H3 Binding in Modular Gp2 Miniproteins
Harthorn, A., Windsor, H. K., Schmitz, Z., Cheung, N., Agwaramgbo, E. & Hackel, B. J., Jul 2026, In: Biotechnology and bioengineering. 123, 7, p. 1871-1881 11 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Engineering a β-Sheet Enables Bispecific Binding in Single VHH Domains
Torres, S., Windsor, H. K., Beaudry, C., Girton, J., Cheung, N. T., Kuo, T. H., Lobb, R. R. & Hackel, B. J., Jun 19 2026, In: ACS Synthetic Biology. 15, 6, p. 2377-2389 13 p.Research output: Contribution to journal › Article › peer-review
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Engineering isoform-selective miniprotein binders to the fetal form of the insulin receptor
Walsh, M. A., Blanchard, P. L., Zhang, X., Cheung, N. T., Yee, D. & Hackel, B. J., 2026, In: Protein Engineering, Design and Selection. 39, gzag025.Research output: Contribution to journal › Article › peer-review
Open Access -
Engineering Murine Cross-Reactivity Into an Affibody to Human Death Receptor 5
Kuo, T. H., Vunnam, N., Sachs, J. N. & Hackel, B. J., Jul 2026, In: Biotechnology and bioengineering. 123, 7, p. 1783-1798 16 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Engineering Affibody Binders to Death Receptor 5 and Tumor Necrosis Factor Receptor 1 With Improved Stability
Nielsen, G. H., Sachs, J. N. & Hackel, B. J., Jun 2025, In: Biotechnology and bioengineering. 122, 6, p. 1386-1396 11 p.Research output: Contribution to journal › Article › peer-review
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