Beau R Webber

20112025

Research output per year

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Research Output

  • 22 Article
  • 3 Comment/debate
  • 1 Review article
  • 1 Other contribution
2020

A Genetically Engineered Primary Human Natural Killer Cell Platform for Cancer Immunotherapy

Pomeroy, E. J., Hunzeker, J. T., Kluesner, M. G., Lahr, W. S., Smeester, B. A., Crosby, M. R., Lonetree, C. L., Yamamoto, K., Bendzick, L., Miller, J. S., Geller, M. A., Walcheck, B., Felices, M., Webber, B. R., Starr, T. K. & Moriarity, B. S., Jan 8 2020, In : Molecular Therapy. 28, 1

Research output: Contribution to journalArticle

Base Editor Correction of COL7A1 in Recessive Dystrophic Epidermolysis Bullosa Patient-Derived Fibroblasts and iPSCs

Osborn, M. J., Newby, G. A., McElroy, A. N., Knipping, F., Nielsen, S. C., Riddle, M. J., Xia, L., Chen, W., Eide, C. R., Webber, B. R., Wandall, H. H., Dabelsteen, S., Blazar, B. R., Liu, D. R. & Tolar, J., Feb 2020, In : Journal of Investigative Dermatology. 140, 2, p. 338-347.e5

Research output: Contribution to journalArticle

4 Scopus citations
2019
Open Access

Erratum: Correction: Rapid DNA replication origin licensing protects stem cell pluripotency (eLife (2017) 6 PII: e49040)

Matson, J. P., Dumitru, R., Coryell, P., Baxley, R. M., Chen, W., Twaroski, K., Webber, B. R., Tolar, J., Bielinsky, A. K., Purvis, J. E. & Cook, J. G., Jun 5 2019, In : eLife. 8

Research output: Contribution to journalComment/debate

Open Access

Highly efficient multiplex human T cell engineering without double-strand breaks using Cas9 base editors

Webber, B. R., Lonetree, C. L., Kluesner, M. G., Johnson, M. J., Pomeroy, E. J., Diers, M. D., Lahr, W. S., Draper, G. M., Slipek, N. J., Smeester, B. S., Lovendahl, K. N., McElroy, A. N., Gordon, W. R., Osborn, M. J. & Moriarity, B. S., Dec 1 2019, In : Nature communications. 10, 1, 5222.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations
2018

Crispr/cas9-based cellular engineering for targeted gene overexpression

Osborn, M. J., Lees, C. J., McElroy, A. N., Merkel, S. C., Eide, C. R., Mathews, W., Feser, C. J., Tschann, M., McElmury, R. T., Webber, B. R., Kim, C. J., Blazar, B. R. & Tolar, J., Apr 2018, In : International journal of molecular sciences. 19, 4, 946.

Research output: Contribution to journalArticle

Open Access
7 Scopus citations

EditR: A Method to Quantify Base Editing from Sanger Sequencing

Kluesner, M. G., Nedveck, D. A., Lahr, W. S., Garbe, J. R., Abrahante, J. E., Webber, B. R. & Moriarity, B. S., Jun 1 2018, In : The CRISPR journal. 1, p. 239-250 12 p.

Research output: Contribution to journalArticle

Open Access

Engineering of Primary Human B cells with CRISPR/Cas9 Targeted Nuclease

Johnson, M. J., Laoharawee, K., Lahr, W. S., Webber, B. R. & Moriarity, B. S., Dec 1 2018, In : Scientific reports. 8, 1, 12144.

Research output: Contribution to journalArticle

Open Access
8 Scopus citations

Highly multiplexed genome engineering using CRISPR/Cas9 gRNA arrays

Kurata, M., Wolf, N. K., Lahr, W. S., Weg, M. T., Kluesner, M. G., Lee, S., Hui, K., Shiraiwa, M., Webber, B. R. & Moriarity, B. S., Sep 2018, In : PloS one. 13, 9, e0198714.

Research output: Contribution to journalArticle

Open Access
8 Scopus citations
2017
Open Access
5 Scopus citations

Aryl hydrocarbon receptor inhibition promotes hematolymphoid development from human pluripotent stem cells

Angelos, M. G., Ruh, P. N., Webber, B. R., Blum, R. H., Ryan, C. D., Bendzick, L., Shim, S., Yingst, A. M., Tufa, D. M., Verneris, M. R. & Kaufman, D. S., Jun 29 2017, In : Blood. 129, 26, p. 3428-3439 12 p.

Research output: Contribution to journalArticle

Open Access
13 Scopus citations

CRISPR/Cas9-mediated correction of the FANCD1 Gene in primary patient cells

Skvarova Kramarzova, K., Osborn, M. J., Webber, B. R., Defeo, A. P., McElroy, A. N., Kim, C. J. & Tolar, J., Jun 14 2017, In : International journal of molecular sciences. 18, 6, 1269.

Research output: Contribution to journalArticle

Open Access
10 Scopus citations

Dermatopontin in Bone Marrow Extracellular Matrix Regulates Adherence but Is Dispensable for Murine Hematopoietic Cell Maintenance

Kramer, A. C., Blake, A. L., Taisto, M. E., Lehrke, M. J., Webber, B. R. & Lund, T. C., Sep 12 2017, In : Stem Cell Reports. 9, 3, p. 770-778 9 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Rapid DNA replication origin licensing protects stem cell pluripotency

Matson, J. P., Dumitru, R., Coryell, P., Baxley, R. M., Chen, W., Twaroski, K., Webber, B. R., Tolar, J., Bielinsky, A. K., Purvis, J. E. & Cook, J. G., Nov 17 2017, In : eLife. 6, e30473.

Research output: Contribution to journalArticle

Open Access
16 Scopus citations

Rapid generation of Col7a1 mouse model of recessive dystrophic epidermolysis bullosa and partial rescue via immunosuppressive dermal mesenchymal stem cells

Webber, B. R., O'Connor, K. T., Mc Elmurry, R. T., Durgin, E. N., Eide, C. R., Lees, C. J., Riddle, M. J., Mathews, W. E., Frank, N. Y., Kluth, M. A., Ganss, C., Moriarity, B. S., Frank, M. H., Osborn, M. J. & Tolar, J., Oct 1 2017, In : Laboratory Investigation. 97, 10, p. 1218-1224 7 p.

Research output: Contribution to journalArticle

Open Access
7 Scopus citations
2016
Open Access
14 Scopus citations

Evaluation of TCR gene editing achieved by TALENs, CRISPR/Cas9, and megaTAL nucleases

Osborn, M. J., Webber, B. R., Knipping, F., Lonetree, C. L., Tennis, N., DeFeo, A. P., McElroy, A. N., Starker, C. G., Lee, C., Merkel, S., Lund, T. C., Kelly-Spratt, K. S., Jensen, M. C., Voytas, D. F., Von Kalle, C., Schmidt, M., Gabriel, R., Hippen, K. L., Miller, J. S., Scharenberg, A. M. & 2 others, Tolar, J. & Blazar, B. R., Mar 1 2016, In : Molecular Therapy. 24, 3, p. 570-581 12 p.

Research output: Contribution to journalArticle

Open Access
75 Scopus citations
2015

Fanconi anemia gene editing by the CRISPR/Cas9 system

Osborn, M. J., Gabriel, R., Webber, B. R., Defeo, A. P., McElroy, A. N., Jarjour, J., Starker, C. G., Wagner, J. E., Joung, J. K., Voytas, D. F., Von Kalle, C., Schmidt, M., Blazar, B. R. & Tolar, J., Feb 1 2015, In : Human gene therapy. 26, 2, p. 114-126 13 p.

Research output: Contribution to journalArticle

72 Scopus citations

From marrow to matrix: Novel gene and cell therapies for epidermolysis bullosa

Webber, B. R. & Tolar, J., Jun 1 2015, In : Molecular Therapy. 23, 6, p. 987-992 6 p.

Research output: Contribution to journalReview article

7 Scopus citations

In vitro T-cell generation from adult, embryonic, and induced pluripotent stem cells: Many roads to one destination

Smith, M. J., Webber, B. R., Mohtashami, M., Stefanski, H. E., Zúñiga-Pflücker, J. C. & Blazar, B. R., Nov 2015, In : Stem Cells. 33, 11, p. 3174-3180 7 p.

Research output: Contribution to journalArticle

6 Scopus citations

Trp53 haploinsufficiency modifies EGFR-driven peripheral nerve sheath tumorigenesis

Rahrmann, E. P., Moriarity, B. S., Otto, G. M., Watson, A. L., Choi, K., Collins, M. H., Wallace, M., Webber, B. R., Forster, C. L., Rizzardi, A. E., Schmechel, S. C., Ratner, N. & Largaespada, D. A., Jul 2014, In : American Journal of Pathology. 184, 7, p. 2082-2098 17 p.

Research output: Contribution to journalArticle

20 Scopus citations
2013

DNA methylation of Runx1 regulatory regions correlates with transition from primitive to definitive hematopoietic potential in vitro and in vivo

Webber, B. R., Iacovino, M., Choi, S. H., Tolar, J., Kyba, M. & Blazar, B. R., Jan 1 2013, In : Blood. 122, 17, p. 2978-2986 9 p.

Research output: Contribution to journalArticle

13 Scopus citations

TALEN-based gene correction for epidermolysis bullosa

Osborn, M. J., Starker, C. G., McElroy, A. N., Webber, B. R., Riddle, M. J., Xia, L., Defeo, A. P., Gabriel, R., Schmidt, M., Von Kalle, C., Carlson, D. F., Maeder, M. L., Joung, J. K., Wagner, J. E., Voytas, D. F., Blazar, B. R. & Tolar, J., Jun 2013, In : Molecular Therapy. 21, 6, p. 1151-1159 9 p.

Research output: Contribution to journalArticle

168 Scopus citations
2011
63 Scopus citations