1980 …2023
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Personal profile

Research interests

  • Crystallography
  • Drug Design
  • Medicinal Chemistry
  • structural biology

Fingerprint The Fingerprint is created by mining the titles and abstracts of the person's research outputs and projects/funding awards to create an index of weighted terms from discipline-specific thesauri.

  • 4 Similar Profiles
Enzymes Medicine & Life Sciences
Biotin Medicine & Life Sciences
Proteins Medicine & Life Sciences
Mycobacterium tuberculosis Medicine & Life Sciences
Crystal structure Chemical Compounds
Ligands Medicine & Life Sciences
Transaminases Medicine & Life Sciences
Crystallization Chemical Compounds

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Projects 2009 2023

Caspase 2

Scaffold Discovery for Caspase-2 by Fragment Screening

Walters, M. A., Finzel, B. C. & Hawkinson, J.

NIH NAT'L INSTITUTE ON AGING (NIA)

4/1/173/31/19

Project: Research project

Caspase 2

Anthrax Toxin Lethal Factor Inhibition Study

Ambrose, E. A., Finzel, B. C., Hook, D., Johnson, R. L. & Walters, M. A.

NIH Nat'l Inst of Allergy & Infect Dis

7/6/096/30/15

Project: Research project

Research Output 1980 2019

Inhibition of HINT1 Modulates Spinal Nociception and NMDA Evoked Behavior in Mice

Shah, R. M., Peterson, C., Strom, A., Dillenburg, M., Finzel, B., Kitto, K. F., Fairbanks, C., Wilcox, G. & Wagner, C. R., Oct 16 2019, In : ACS Chemical Neuroscience. 10, 10, p. 4385-4393 9 p.

Research output: Contribution to journalArticle

Nociception
N-Methylaspartate
Opioid Analgesics
N-Methyl-D-Aspartate Receptors
Aptitude
1 Citation (Scopus)

Structure and Functional Characterization of Human Histidine Triad Nucleotide-Binding Protein 1 Mutations Associated with Inherited Axonal Neuropathy with Neuromyotonia

Shah, R. M., Maize, K. M., West, H. T., Strom, A. M., Finzel, B. C. & Wagner, C. R., Aug 17 2018, In : Journal of Molecular Biology. 430, 17, p. 2709-2721 13 p.

Research output: Contribution to journalArticle

Isaacs Syndrome
Mutation
Enzymes
Adenosine Monophosphate
Histidine
2 Citations (Scopus)

A Crystal Structure Based Guide to the Design of Human Histidine Triad Nucleotide Binding Protein 1 (hHint1) Activated ProTides

Maize, K. M., Shah, R., Strom, A., Kumarapperuma, S., Zhou, A., Wagner, C. R. & Finzel, B. C., Nov 6 2017, In : Molecular pharmaceutics. 14, 11, p. 3987-3997 11 p.

Research output: Contribution to journalArticle

Nucleosides
nucleoside phosphotransferase
Prodrugs
Nucleotides
Calorimetry
8 Citations (Scopus)
Protons
Trajectories
Catalysis
Proton transfer
Enzymes
4 Citations (Scopus)
Neuralgia
Histidine
Analgesia
Opioid Analgesics
Metal ions