Projects per year
Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Research Interest Keywords
- Crystallography
- Drug Design
- Medicinal Chemistry
- structural biology
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Caspase-2 Probe Compounds
Ashe, K. H., Finzel, B. C. & Nelson, K.
NIH NAT'L INSTITUTE ON AGING (NIA)
2/15/19 → 11/30/23
Project: Research project
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Chemical probes as allosteric modulators of CK2 alpha prime targeting Huntington's disease
Walters, M. A., Finzel, B. C. & Nelson, K.
NIH NAT INST OF NEURO DISORDERS & STROKE
2/15/21 → 1/31/23
Project: Research project
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Scaffold Discovery for Caspase-2 by Fragment Screening
Walters, M. A., Finzel, B. C. & Hawkinson, J.
NIH NAT'L INSTITUTE ON AGING (NIA)
4/1/17 → 3/31/19
Project: Research project
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Anthrax Toxin Lethal Factor Inhibition Study
Ambrose, E. A., Finzel, B. C., Hook, D., Johnson, R. L. & Walters, M. A.
NIH Nat'l Inst of Allergy & Infect Dis
7/6/09 → 6/30/15
Project: Research project
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Characterization of caspase-2 inhibitors based on specific sites of caspase-2-mediated proteolysis
Bresinsky, M., Strasser, J. M., Hubmann, A., Vallaster, B., McCue, B., Fuller, J. L., Singh, G., Nelson, K., Cuellar, M. E., Finzel, B. C., Ashe, K. H., Walters, M. A. & Pockes, S., Sep 2022, In: Archiv der Pharmazie. 355, 9, 2200095.Research output: Contribution to journal › Article › peer-review
Open Access -
Structural Characterization of the Human Cytosolic Malate Dehydrogenase I
McCue, W. M. & Finzel, B. C., Jan 11 2022, In: ACS Omega. 7, 1, p. 207-214 8 p.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Structure-Based Design and Biological Evaluation of Novel Caspase-2 Inhibitors Based on the Peptide AcVDVAD-CHO and the Caspase-2-Mediated Tau Cleavage Sequence YKPVD314
Bresinsky, M., Strasser, J. M., Vallaster, B., Liu, P., McCue, B., Fuller, J., Hubmann, A., Singh, G., Nelson, K., Cuellar, M. E., Wilmot, C. M., Finzel, B. C., Ashe, K. H., Walters, M. A. & Pockes, S., Jan 14 2022, In: ACS Pharmacology and Translational Science. 5, 1, p. 20-40 21 p.Research output: Contribution to journal › Article › peer-review
5 Scopus citations -
Inhibition of HINT1 Modulates Spinal Nociception and NMDA Evoked Behavior in Mice
Shah, R. M., Peterson, C., Strom, A., Dillenburg, M., Finzel, B., Kitto, K. F., Fairbanks, C., Wilcox, G. & Wagner, C. R., Oct 16 2019, In: ACS Chemical Neuroscience. 10, 10, p. 4385-4393 9 p.Research output: Contribution to journal › Article › peer-review
9 Scopus citations -
Structure and Functional Characterization of Human Histidine Triad Nucleotide-Binding Protein 1 Mutations Associated with Inherited Axonal Neuropathy with Neuromyotonia
Shah, R. M., Maize, K. M., West, H. T., Strom, A. M., Finzel, B. C. & Wagner, C. R., Aug 17 2018, In: Journal of Molecular Biology. 430, 17, p. 2709-2721 13 p.Research output: Contribution to journal › Article › peer-review
Open Access7 Scopus citations