Baolin Wu

20032023

Research output per year

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Research Output

2019

A general statistic to test an optimally weighted combination of common and/or rare variants

Zhang, J., Wu, B., Sha, Q., Zhang, S. & Wang, X., Dec 1 2019, In : Genetic epidemiology. 43, 8, p. 966-979 14 p.

Research output: Contribution to journalArticle

Analysis of 75 candidate SNPs associated with acute rejection in kidney transplant recipients: Validation of rs2910164 in MicroRNA MIR146A

Oetting, W. S., Schladt, D. P., Dorr, C. R., Wu, B., Guan, W., Remmel, R. P., Iklé, D., Mannon, R. B., Matas, A. J., Israni, A. K. & Jacobson, P. A., Aug 1 2019, In : Transplantation. 103, 8, p. 1591-1602 12 p.

Research output: Contribution to journalArticle

2 Scopus citations

Genetic variants associated with immunosuppressant pharmacokinetics and adverse effects in the DeKAF genomics genome-wide association studies

Oetting, W. S., Wu, B., Schladt, D. P., Guan, W., Van Setten, J., Keating, B. J., Iklé, D., Remmel, R. P., Dorr, C. R., Mannon, R. B., Matas, A. J., Israni, A. K. & Jacobson, P. A., Jun 1 2019, In : Transplantation. 103, 6, p. 1131-1139 9 p.

Research output: Contribution to journalArticle

2 Scopus citations
3 Scopus citations

Integrate multiple traits to detect novel trait–gene association using GWAS summary data with an adaptive test approach

Guo, B. & Wu, B., Jul 1 2019, In : Bioinformatics. 35, 13, p. 2251-2257 7 p.

Research output: Contribution to journalArticle

1 Scopus citations

Pleiotropy informed adaptive association test of multiple traits using genome-wide association study summary data

Masotti, M., Guo, B. & Wu, B., Dec 1 2019, In : Biometrics. 75, 4, p. 1076-1085 10 p.

Research output: Contribution to journalArticle

Powerful and efficient SNP-set association tests across multiple phenotypes using GWAS summary data

Guo, B. & Wu, B., Jan 1 2019, In : Bioinformatics. 35, 8, p. 1366-1372 7 p.

Research output: Contribution to journalArticle

1 Scopus citations

Powerful statistical method to detect disease-associated genes using publicly available genome-wide association studies summary data

Zhang, J., Zhao, Z., Guo, X., Guo, B. & Wu, B., Dec 1 2019, In : Genetic epidemiology. 43, 8, p. 941-951 11 p.

Research output: Contribution to journalArticle

1 Scopus citations

Tacrolimus troughs and genetic determinants of metabolism in kidney transplant recipients: A comparison of four ancestry groups

the DeKAF Genomics and GEN03 Investigators, Oct 1 2019, In : American Journal of Transplantation. 19, 10, p. 2795-2804 10 p.

Research output: Contribution to journalArticle

3 Scopus citations
2018

Attempted validation of 44 reported SNPs associated with tacrolimus troughs in a cohort of kidney allograft recipients

Oetting, W. S., Wu, B., Schladt, D. P., Guan, W., Remmel, R. P., Dorr, C., Mannon, R. B., Matas, A. J., Israni, A. K. & Jacobson, P. A., Feb 2018, In : Pharmacogenomics. 19, 3, p. 175-184 10 p.

Research output: Contribution to journalArticle

7 Scopus citations

beta-Glucuronidase Gene Expression in Stool Samples Associated with Chronic Allograft Dysfunction in Kidney Transplants.

Israni, A., Knights, D., Al-Ghalith, G., Muthusamy, A., Wu, B., Oetting, W., Schaldt, D., Remmel, R. & Jacobson, P., 2018, p. 807. 1 p.

Research output: Contribution to conferencePaper

Open Access
1 Scopus citations

Genome-Wide Association Meta-Analysis for Acute Rejection of Kidney Transplants

Israni, A. K., Jacobson, P. A., Guan, W., Dorr, C. R., van Setten, J., de Borst, M. H., Stapleton, C. P., Phelan, P. J., Conlon, P. J., Birdwell, K. A., Reindl-Schwaighofer, R., Heinzel, A., Bakker, S. J., Cavelleri, G., Oetting, W. S., Schladt, D. P., Kwok, P-Y., Eikmans, M., Snieder, H., Wu, B. & 5 others, Bassaganyas, L., Yang, J., van der Most, P. J., Asselbergs, F. W. & Keating, B., 2018, In : Transplantation. 102, p. S27

Research output: Contribution to journalArticle

14 Scopus citations

Reader reaction on the fast small-sample kernel independence test for microbiome community-level association analysis

Guo, B. & Wu, B., Sep 2018, In : Biometrics. 74, 3, p. 1120-1124 5 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Statistical methods to detect novel genetic variants using publicly available GWAS summary data

Guo, B. & Wu, B., Jun 2018, In : Computational Biology and Chemistry. 74, p. 76-79 4 p.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

Tacrolimus Elimination in Four Patients With a CYP3A5*3/*3 CYP3A4*22/*22 Genotype Combination

Scheibner, A., Remmel, R. P., Schladt, D., Oetting, W. S., Guan, W., Wu, B., Dorr, C., Israni, A. & Jacobson, P. A., Jul 2018, In : Pharmacotherapy. 38, 7, p. e46-e52

Research output: Contribution to journalArticle

Open Access
3 Scopus citations
Open Access
5 Scopus citations

Urinary microbiome associated with chronic allograft dysfunction in kidney transplant recipients

Wu, J. F., Muthusamy, A., Al-Ghalith, G. A., Knights, D., Guo, B., Wu, B., Remmel, R. P., Schladt, D. P., Alegre, M. L., Oetting, W. S., Jacobson, P. A. & Israni, A. K., Dec 2018, In : Clinical Transplantation. 32, 12, e13436.

Research output: Contribution to journalArticle

4 Scopus citations

Validation of Genetic Variants Identified in GWAS for Tacrolimus Troughs.

Jacobson, P., Schladt, D., Guan, W., van Setten, J., Remmel, R., Wu, B., Dorr, C., Keating, B., Ikle, D. & Mannon, R., 2018, p. 793. 1 p.

Research output: Contribution to conferencePaper

2017

CRISPR/Cas9 genetic modification of CYP3A5 *3 in HuH-7 human hepatocyte cell line leads to cell lines with increased midazolam and tacrolimus metabolism

Dorr, C. R., Remmel, R. P., Muthusamy, A., Fisher, J., Moriarity, B. S., Yasuda, K., Wu, B., Guan, W., Schuetz, E. G., Oetting, W. S., Jacobson, P. A. & Israni, A. K., Aug 1 2017, In : Drug Metabolism and Disposition. 45, 8, p. 957-965 9 p.

Research output: Contribution to journalArticle

Open Access
10 Scopus citations

Genome-wide association test of multiple continuous traits using imputed SNPs

Wu, B. & Pankow, J. S., Jan 1 2017, In : Statistics and its Interface. 10, 3, p. 379-386 8 p.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Personalized Tacrolimus (TAC) Dosing Using Genetic Variants in Caucasian Kidney Transplant (Tx) Recipients

Margraf, D., Brundage, R., Schladt, D., Guan, W., Wu, B., Remmel, R., Dorr, C., Berglund, D., Mannon, R. & Matas, A., 2017, p. 736. 1 p.

Research output: Contribution to conferenceAbstract

Tacrolimus Dose Variability, CYP3A5 Genotype, and Acute Rejection in African American and European American Kidney Transplant Recipients

Seibert, S. R., Schladt, D., Wu, B., Guan, W., Dorr, C., Berglund, D., Remmel, R., Matas, A., Mannon, R. & Israni, A., 2017, p. 732. 1 p.

Research output: Contribution to conferencePaper

2016

High-Risk Pharmacogenetic (PGx) Variants in Kidney Transplant (tx) Recipients

Berglund, D., Schladt, D., Sanghavi, K., Guan, W., Wu, B., Dorr, C., Remmel, R., Mannon, R., Matas, A. & Oetting, W., 2016, p. 321. 1 p.

Research output: Contribution to conferencePaper

Marked Alterations in Gene Expression in Peripheral Blood Leukocytes of Kidney Transplant (tx) Recipients Following Mycophenolic Acid (MPA) Treatment.

Sanghavi, K., Wu, B., Dorr, C., Muthuswamy, A., Guan, W., Schladt, D., Remmel, R., Ilke, D., Matas, A. & Israni, A., 2016, p. 783. 1 p.

Research output: Contribution to conferencePaper

12 Scopus citations

On Sample Size and Power Calculation for Variant Set-Based Association Tests

Wu, B. & Pankow, J. S., Mar 1 2016, In : Annals of Human Genetics. 80, 2, p. 136-143 8 p.

Research output: Contribution to journalArticle

6 Scopus citations
Open Access
5 Scopus citations

Sequence Kernel Association Test of Multiple Continuous Phenotypes

Wu, B. & Pankow, J. S., Feb 1 2016, In : Genetic epidemiology. 40, 2, p. 91-100 10 p.

Research output: Contribution to journalArticle

Open Access
20 Scopus citations
2015

Concept and design of a genome-wide association genotyping array tailored for transplantation-specific studies

Li, Y. R., van Setten, J., Verma, S. S., Lu, Y., Holmes, M. V., Gao, H., Lek, M., Nair, N., Chandrupatla, H., Chang, B., Karczewski, K. J., Wong, C., Mohebnasab, M., Mukhtar, E., Phillips, R., Tragante, V., Hou, C., Steel, L., Lee, T., Garifallou, J. & 46 others, Guettouche, T., Cao, H., Guan, W., Himes, A., van Houten, J., Pasquier, A., Yu, R., Carrigan, E., Miller, M. B., Schladt, D., Akdere, A., Gonzalez, A., Llyod, K. M., McGinn, D., Gangasani, A., Michaud, Z., Colasacco, A., Snyder, J., Thomas, K., Wang, T., Wu, B., Alzahrani, A. J., Al-Ali, A. K., Al-Muhanna, F. A., Al-Rubaish, A. M., Al-Mueilo, S., Monos, D. S., Murphy, B., Olthoff, K. M., Wijmenga, C., Webster, T., Kamoun, M., Balasubramanian, S., Lanktree, M. B., Oetting, W. S., Garcia-Pavia, P., MacArthur, D. G., de Bakker, P. I. W., Hakonarson, H., Birdwell, K. A., Jacobson, P. A., Ritchie, M. D., Asselbergs, F. W., Israni, A. K., Shaked, A. & Keating, B. J., Oct 1 2015, In : Genome medicine. 7, 1, 90.

Research output: Contribution to journalArticle

32 Scopus citations

Design and implementation of the international genetics and translational research in transplantation network

Keating, B. J., Van Setten, J., Jacobson, P. A., Holmes, M. V., Verma, S. S., Chandrupatla, H. R., Nair, N., Gao, H., Li, Y. R., Chang, B. L., Wong, C., Phillips, R., Cole, B. S., Mukhtar, E., Zhang, W., Cao, H., Mohebnasab, M., Hou, C., Lee, T., Steel, L. & 31 others, Shaked, O., Garifallou, J., Miller, M. B., Karczewski, K. J., Akdere, A., Gonzalez, A., Lloyd, K. M., McGinn, D., Michaud, Z., Colasacco, A., Lek, M., Fu, Y., Pawashe, M., Guettouche, T., Himes, A., Perez, L., Guan, W., Wu, B., Schladt, D., Menon, M., Zhang, Z., Tragante, V., De Jonge, N., Otten, H. G., De Weger, R. A., Van De Graaf, E. A., Baan, C. C., Manintveld, O. C., De Vlaminck, I., Oetting, W. S. & The International Genetics & Translational Research in Transplantation Network (iGeneTRAiN), Oct 23 2015, In : Transplantation. 99, 11, p. 2401-2412 12 p.

Research output: Contribution to journalArticle

32 Scopus citations

Differentially expressed gene transcripts using RNA sequencing from the blood of immunosuppressed kidney allograft recipients

Dorr, C., Wu, B., Guan, W., Muthusamy, A., Sanghavi, K., Schladt, D. P., Maltzman, J. S., Scherer, S. E., Brott, M. J., Matas, A. J., Jacobson, P. A., Oetting, W. S. & Israni, A. K., May 6 2015, In : PloS one. 10, 5, e0125045.

Research output: Contribution to journalArticle

17 Scopus citations

Network-Based Isoform Quantification with RNA-Seq Data for Cancer Transcriptome Analysis

Zhang, W., Chang, J. W., Lin, L., Minn, K., Wu, B., Chien, J., Yong, J., Zheng, H. & Kuang, R., Jan 1 2015, In : PLoS computational biology. 11, 12, e1004465.

Research output: Contribution to journalArticle

5 Scopus citations

Reader reaction on the generalized Kruskal-Wallis test for genetic association studies incorporating group uncertainty

Wu, B. & Guan, W., Jun 1 2015, In : Biometrics. 71, 2, p. 556-557 2 p.

Research output: Contribution to journalArticle

1 Scopus citations
12 Scopus citations

Single nucleotide polymorphisms (SNPs) Associated with Acute Rejection in European American Kidney Transplant Recipients: a Genome Wide Association Study (GWAS)

Israni, A., Dorr, C., Miller, M., Schladt, D., Sanghavi, K., Muthusamy, A., Remmel, R., Guan, W., Wu, B. & Oetting, W., 2015.

Research output: Contribution to conferencePaper

8 Scopus citations
2014

Likelihood-Based Approach to Gene Set Enrichment Analysis with a Finite Mixture Model

Lee, S. M., Wu, B. & Kersey, J. H., Jan 1 2014, In : Statistics in Biosciences. 6, 1, p. 38-54 17 p.

Research output: Contribution to journalArticle

1 Scopus citations

Proteomic profiles in acute respiratory distress syndrome differentiates survivors from non-survivors

Bhargava, M., Becker, T. L., Viken, K. J., Jagtap, P. D., Dey, S., Steinbach, M. S., Wu, B., Kumar, V., Bitterman, P. B., Ingbar, D. H. & Wendt, C. H., Oct 7 2014, In : PloS one. 9, 10, e109713.

Research output: Contribution to journalArticle

25 Scopus citations
2013

A note on statistical method for genotype calling of high-throughput single-nucleotide polymorphism arrays

Yang, J., Zhang, W. & Wu, B., Jun 1 2013, In : Journal of Applied Statistics. 40, 6, p. 1372-1381 10 p.

Research output: Contribution to journalArticle

Empirical null distribution-based modeling of multi-class differential gene expression detection

Cao, X., Wu, B. & Hertz, M. I., Feb 1 2013, In : Journal of Applied Statistics. 40, 2, p. 347-357 11 p.

Research output: Contribution to journalArticle

Network-based Survival Analysis Reveals Subnetwork Signatures for Predicting Outcomes of Ovarian Cancer Treatment

Zhang, W., Ota, T., Shridhar, V., Chien, J., Wu, B. & Kuang, R., Apr 15 2013, In : PLoS computational biology. 9, 3, e1002975.

Research output: Contribution to journalArticle

85 Scopus citations
2 Scopus citations
10 Scopus citations
2 Scopus citations
2012

Signed network propagation for detecting differential gene expressions and DNA copy number variations

Zhang, W., Johnson, N., Wu, B. & Kuang, R., Nov 26 2012, 2012 ACM Conference on Bioinformatics, Computational Biology and Biomedicine, BCB 2012. p. 337-344 8 p. (2012 ACM Conference on Bioinformatics, Computational Biology and Biomedicine, BCB 2012).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

8 Scopus citations

Sparse regularized discriminant analysis with application to microarrays

Li, R. & Wu, B., Aug 1 2012, In : Computational Biology and Chemistry. 39, p. 14-19 6 p.

Research output: Contribution to journalArticle

1 Scopus citations
2011

A permutation test approach to the choice of size k for the nearest neighbors classifier

Lai, Y., Wu, B. & Zhao, H., Oct 1 2011, In : Journal of Applied Statistics. 38, 10, p. 2289-2302 14 p.

Research output: Contribution to journalArticle

2010

LTQ-iQuant: A freely available software pipeline for automated and accurate protein quantification of isobaric tagged peptide data from LTQ instruments

Onsongo, G., Stone, M. D., Van Riper, S. K., Chilton, J., Wu, B., Higgins, L., Lund, T. C., Carlis, J. V. & Griffin, T. J., Oct 1 2010, In : Proteomics. 10, 19, p. 3533-3538 6 p.

Research output: Contribution to journalArticle

21 Scopus citations