Atsushi Asakura

1987 …2021

Research output per year

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Article
2020

Transcriptional and cytopathological hallmarks of FSHD in chronic DUX4-expressing mice

Bosnakovski, D., Shams, A. S., Yuan, C., da Silva, M. T., Ener, E. T., Baumann, C. W., Lindsay, A. J., Verma, M., Asakura, A., Lowe, D. A. & Kyba, M., May 1 2020, In : Journal of Clinical Investigation. 130, 5, p. 2465-2477 13 p.

Research output: Contribution to journalArticle

Open Access
2019

Increasing myosin light chain 3f (MLC3f) protects against a decline in contractile velocity

Kim, J. H., Graber, T. G., Liu, H., Asakura, A. & Thompson, L. D. V., Apr 2019, In : PloS one. 14, 4, e0214982.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Inhibition of FLT1 ameliorates muscular dystrophy phenotype by increased vasculature in a mouse model of Duchenne muscular dystrophy

Verma, M., Shimizu-Motohashi, Y., Asakura, Y., Ennen, J. P., Bosco, J., Zhou, Z., Fong, G. H., Josiah, S., Keefe, D. & Asakura, A., Jan 1 2019, In : PLoS genetics. 15, 12, e1008468.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Tbx1 regulates inherited metabolic and myogenic abilities of progenitor cells derived from slow- and fast-type muscle

Motohashi, N., Uezumi, A., Asakura, A., Ikemoto-Uezumi, M., Mori, S., Mizunoe, Y., Takashima, R., Miyagoe-Suzuki, Y., Takeda, S. & Shigemoto, K., Jun 1 2019, In : Cell Death and Differentiation. 26, 6, p. 1024-1036 13 p.

Research output: Contribution to journalArticle

3 Scopus citations
2018

Cellular localization of the cell cycle inhibitor Cdkn1c controls growth arrest of adult skeletal muscle stem cells

Mademtzoglou, D., Asakura, Y., Borok, M. J., Alonso-Martin, S., Mourikis, P., Kodaka, Y., Mohan, A., Asakura, A. & Relaix, F., Oct 2018, In : eLife. 7, e33337.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations

Cry2 Is Critical for Circadian Regulation of Myogenic Differentiation by Bclaf1-Mediated mRNA Stabilization of Cyclin D1 and Tmem176b

Lowe, M., Lage, J., Paatela, E., Munson, D., Hostager, R., Yuan, C., Katoku-Kikyo, N., Ruiz-Estevez, M., Asakura, Y., Staats, J., Qahar, M., Lohman, M., Asakura, A. & Kikyo, N., Feb 20 2018, In : Cell reports. 22, 8, p. 2118-2132 15 p.

Research output: Contribution to journalArticle

Open Access
6 Scopus citations

Muscle Satellite Cell Cross-Talk with a Vascular Niche Maintains Quiescence via VEGF and Notch Signaling

Verma, M., Asakura, Y., Murakonda, B. S. R., Pengo, T., Latroche, C., Chazaud, B., McLoon, L. K. & Asakura, A., Oct 4 2018, In : Cell Stem Cell. 23, 4, p. 530-543.e9

Research output: Contribution to journalArticle

Open Access
30 Scopus citations

Promotion of Myoblast Differentiation by Fkbp5 via Cdk4 Isomerization

Ruiz-Estevez, M., Staats, J., Paatela, E., Munson, D., Katoku-Kikyo, N., Yuan, C., Asakura, Y., Hostager, R., Kobayashi, H., Asakura, A. & Kikyo, N., Nov 27 2018, In : Cell reports. 25, 9, p. 2537-2551.e8

Research output: Contribution to journalArticle

Open Access
3 Scopus citations
2017

Loss of MyoD Promotes Fate Transdifferentiation of Myoblasts Into Brown Adipocytes

Wang, C., Liu, W., Nie, Y., Qaher, M., Horton, H. E., Yue, F., Asakura, A. & Kuang, S., Feb 1 2017, In : EBioMedicine. 16, p. 212-223 12 p.

Research output: Contribution to journalArticle

Open Access
18 Scopus citations

Spin infection enables efficient gene delivery to muscle stem cells

Kodaka, Y., Asakura, Y. & Asakura, A., Jan 1 2017, In : BioTechniques. 63, 2, p. 72-76 5 p.

Research output: Contribution to journalArticle

Open Access
2016

Skeletal muscle tissue clearing for LacZ and fluorescent reporters, and immunofluorescence staining

Verma, M., Murkonda, B. S., Asakura, Y. & Asakura, A., Jan 1 2016, In : Methods in Molecular Biology. 1460, p. 129-140 12 p.

Research output: Contribution to journalArticle

5 Scopus citations
2015

Pregnancy-induced amelioration of muscular dystrophy phenotype in mdx mice via muscle membrane stabilization effect of glucocorticoid

Yuko, S. M., Yoko, A., Norio, M., Nandkishore, R. B., Michael, G. B. & Atsushi, A., Mar 16 2015, In : PloS one. 10, 3, e0120325.

Research output: Contribution to journalArticle

2 Scopus citations
2014

Grand challenges in the field of stem cell research

Asakura, A., Feb 13 2014, In : Frontiers in Cell and Developmental Biology. 2, FEB, 2.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

Isolation, culture, and transplantation of muscle satellite cells

Motohashi, N., Asakura, Y. & Asakura, A., Apr 8 2014, In : Journal of Visualized Experiments. 85, e50846.

Research output: Contribution to journalArticle

49 Scopus citations
2012

Constitutive Notch Activation Upregulates Pax7 and promotes the self-renewal of skeletal muscle satellite cells

Wen, Y., Bi, P., Liu, W., Asakura, A., Keller, C. & Kuang, S., Jun 15 2012, In : Molecular and cellular biology. 32, 12, p. 2300-2311 12 p.

Research output: Contribution to journalArticle

146 Scopus citations

Increased angiogenesis and improved left ventricular function after transplantation of myoblasts lacking the MyoD gene into infarcted myocardium

Nakamura, Y., Asakura, Y., Piras, B. A., Hirai, H., Tastad, C. T., Verma, M., Christ, A. J., Zhang, J., Yamazaki, T., Yoshiyama, M. & Asakura, A., Jul 25 2012, In : PloS one. 7, 7, e41736.

Research output: Contribution to journalArticle

12 Scopus citations

Myosin light chain 3f attenuates age-induced decline in contractile velocity in MHC type II single muscle fibers

Kim, J. H., Torgerud, W. S., Mosser, K. H. H., Hirai, H., Watanabe, S., Asakura, A. & Thompson, L. V., Apr 1 2012, In : Aging cell. 11, 2, p. 203-212 10 p.

Research output: Contribution to journalArticle

12 Scopus citations
2011
4 Scopus citations

MyoD gene suppression by Oct4 is required for reprogramming in myoblasts to produce induced pluripotent stem cells

Watanabe, S., Hirai, H., Asakura, Y., Tastad, C., Verma, M., Keller, C., Dutton, J. R. & Asakura, A., Mar 1 2011, In : STEM CELLS. 29, 3, p. 505-516 12 p.

Research output: Contribution to journalArticle

31 Scopus citations
2010

Flt-1 haploinsufficiency ameliorates muscular dystrophy phenotype by developmentally increased vasculature in mdx mice

Verma, M., Asakura, Y., Hirai, H., Watanabe, S., Tastad, C., Fong, G. H., Ema, M., Call, J. A., Lowe, D. A. & Asakura, A., Aug 12 2010, In : Human molecular genetics. 19, 21, p. 4145-4159 15 p., ddq334.

Research output: Contribution to journalArticle

31 Scopus citations

MyoD regulates apoptosis of myoblasts through microRNA-mediated down-regulation of Pax3

Hirai, H., Verma, M., Watanabe, S., Tastad, C., Asakura, Y. & Asakura, A., Oct 18 2010, In : Journal of Cell Biology. 191, 2, p. 347-365 19 p.

Research output: Contribution to journalArticle

116 Scopus citations

Post-mitotic role of nucleostemin as a promoter of skeletal muscle cell differentiation

Hirai, H., Romanova, L., Kellner, S., Verma, M., Rayner, S., Asakura, A. & Kikyo, N., Jan 1 2010, In : Biochemical and Biophysical Research Communications. 391, 1, p. 299-304 6 p.

Research output: Contribution to journalArticle

10 Scopus citations
2007

Hematopoietic potential cells in skeletal muscle

Asakura, A., Oct 1 2007, In : Cell Research. 17, 10, p. 836-838 3 p.

Research output: Contribution to journalArticle

1 Scopus citations

Increased survival of muscle stem cells lacking the MyoD gene after transplantation into regenerating skeletal muscle

Asakura, A., Hirai, H., Kablar, B., Morita, S., Ishibashi, J., Piras, B. A., Christ, A. J., Verma, M., Vineretsky, K. A. & Rudnicki, M. A., Oct 16 2007, In : Proceedings of the National Academy of Sciences of the United States of America. 104, 42, p. 16552-16557 6 p.

Research output: Contribution to journalArticle

82 Scopus citations

Resident endothelial precursors in muscle, adipose, and dermis contribute to postnatal vasculogenesis

Grenier, G., Scim̀e, A., Le Grand, F., Asakura, A., Perez-Iratxeta, C., Andrade-Navarro, M. A., Labosky, P. A. & Rudnicki, M. A., Dec 1 2007, In : STEM CELLS. 25, 12, p. 3101-3110 10 p.

Research output: Contribution to journalArticle

66 Scopus citations

Xenotransplantation of long-term-cultured swine bone marrow-derived mesenchymal stem cells

Nakamura, Y., Wang, X., Xu, C., Asakura, A., Yoshiyama, M., From, A. H. L. & Zhang, J., Mar 1 2007, In : STEM CELLS. 25, 3, p. 612-620 9 p.

Research output: Contribution to journalArticle

64 Scopus citations
2005

MyoD induces myogenic differentiation through cooperation of its NH 2- and COOH-terminal regions

Ishibashi, J., Perry, R. L., Asakura, A. & Rudnicki, M. A., Nov 7 2005, In : Journal of Cell Biology. 171, 3, p. 471-482 12 p.

Research output: Contribution to journalArticle

100 Scopus citations
2004

MyoD enhances BMP7-induced osteogenic differentiation of myogenic cell cultures

Komaki, M., Asakura, A., Rudnicki, M. A., Sodek, J. & Cheifetz, S., Mar 15 2004, In : Journal of cell science. 117, 8, p. 1457-1468 12 p.

Research output: Contribution to journalArticle

19 Scopus citations

STE20-like kinase SLK displays myofiber type specificity and is involved in C2C12 myoblast differentiation

Storbeck, C. J., Daniel, K., Zhang, Y. H., Lunde, J., Scime, A., Asakura, A., Jasmin, B., Korneluk, R. G. & Sabourin, L. A., Apr 1 2004, In : Muscle and Nerve. 29, 4, p. 553-564 12 p.

Research output: Contribution to journalArticle

17 Scopus citations
2002

Myogenic specification of side population cells in skeletal muscle

Asakura, A., Seale, P., Girgis-Gabardo, A. & Rudnicki, M. A., Oct 14 2002, In : Journal of Cell Biology. 159, 1, p. 123-134 12 p.

Research output: Contribution to journalArticle

553 Scopus citations

Side population cells from diverse adult tissues are capable of in vitro hematopoietic differentiation

Asakura, A. & Rudnicki, M. A., Nov 1 2002, In : Experimental Hematology. 30, 11, p. 1339-1345 7 p.

Research output: Contribution to journalArticle

274 Scopus citations
2001

Muscle satellite cells are multipotential stem cells that exhibit myogenic, osteogenic, and adipogenic differentiation

Asakura, A., Komaki, M. & Rudnicki, M. A., Oct 2001, In : Differentiation. 68, 4-5, p. 245-253 9 p.

Research output: Contribution to journalArticle

585 Scopus citations

NeuroD2 is necessary for development and survival of central nervous system neurons

Olson, J. M., Asakura, A., Snider, L., Hawkes, R., Strand, A., Stoeck, J., Hallahan, A., Pritchard, J. & Tapscott, S. J., Jun 1 2001, In : Developmental Biology. 234, 1, p. 174-187 14 p.

Research output: Contribution to journalArticle

96 Scopus citations
1999

Reduced differentiation potential of primary MyoD-/- myogenic cells derived from adult skeletal muscle

Sabourin, L. A., Girgis-Gabardo, A., Scale, P., Asakura, A. & Rudnicki, M. A., Feb 22 1999, In : Journal of Cell Biology. 144, 4, p. 631-643 13 p.

Research output: Contribution to journalArticle

239 Scopus citations
1998

Apoptosis of epaxial myotome in Danforth's shorttail (Sd) mice in somites that form following notochord degeneration

Asakura, A. & Tapscott, S. J., Nov 15 1998, In : Developmental Biology. 203, 2, p. 276-289 14 p.

Research output: Contribution to journalArticle

28 Scopus citations

MyoD and Myf-5 define the specification of musculature of distinct embryonic origin

Kablar, B., Asakura, A., Krastel, K., Ying, C., May, L. L., Goldhamer, D. J. & Rudnicki, M. A., Jan 1 1998, In : Biochemistry and Cell Biology. 76, 6, p. 1079-1091 13 p.

Research output: Contribution to journalArticle

61 Scopus citations
1997

MyoD and Myf-5 differentially regulate the development of limb versus trunk skeletal muscle

Kablar, B., Krastel, K., Ying, C., Asakura, A., Tapscott, S. J. & Rudnicki, M. A., Dec 1 1997, In : Development. 124, 23, p. 4729-4738 10 p.

Research output: Contribution to journalArticle

216 Scopus citations
1996

neuroD2 and neuroD3: Distinct expression patterns and transcriptional activation potentials within the neuroD gene family

McCormick, M. B., Tamimi, R. M., Snider, L., Asakura, A., Bergstrom, D. & Tapscott, S. J., Jan 1 1996, In : Molecular and cellular biology. 16, 10, p. 5792-5800 9 p.

Research output: Contribution to journalArticle

140 Scopus citations
1995

The Regulation of MyoD Gene Expression: Conserved Elements Mediate Expression in Embryonic Axial Muscle

Asakura, A., Lyons, G. E. & Tapscott, S. J., Oct 1995, In : Developmental Biology. 171, 2, p. 386-398 13 p.

Research output: Contribution to journalArticle

95 Scopus citations
1993

MyoD and myogenin act on the chicken myosin light-chain 1 gene as distinct transcriptional factors

Asakura, A., Fujisawa-Sehara, A., Komiya, T., Nabeshima, Y. & Nabeshima, Y. I., Jan 1 1993, In : Molecular and cellular biology. 13, 11, p. 7153-7162 10 p.

Research output: Contribution to journalArticle

39 Scopus citations
1992

Differential trans-activation of muscle-specific regulatory elements including the mysosin light chain box by chicken MyoD, myogenin, and MRF4

Fujisawa-Sehara, A., Nabeshima, Y., Komiya, T., Uetsuki, T., Asakura, A. & Nabeshima, Y. I., Jan 1 1992, In : Journal of Biological Chemistry. 267, 14, p. 10031-10038 8 p.

Research output: Contribution to journalArticle

48 Scopus citations

Positive and negative gene regulation in muscle.

Nabeshima, Y., Uetsuki, T., Komiya, T., Nabeshima, Y., Asakura, A., Kamijo, K., Yagami, T. & Fujisawa-Sehara, A., 1992, In : Symposia of the Society for Experimental Biology. 46, p. 343-353 11 p.

Research output: Contribution to journalArticle

1987

Is Nebulin the Product of Duchenne Muscular Dystrophy Gene?

Sugita, H., Nonaka, I., Itoh, Y., Asakura, A., Hu, D. H., Kimura, S. & Maruyama, K., Jan 1 1987, In : Proceedings of the Japan Academy Series B: Physical and Biological Sciences. 63, 3, p. 107-110 4 p.

Research output: Contribution to journalArticle

Open Access
24 Scopus citations