1978 …2018

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2018

Morphine worsens the severity and prevents pancreatic regeneration in mouse models of acute pancreatitis

Barlass, U., Dutta, R., Cheema, H., George, J., Sareen, A., Dixit, A., Yuan, Z., Giri, B., Meng, J., Banerjee, S., Banerjee, S., Dudeja, V., Dawra, R. K., Roy, S. & Saluja, A. K., Apr 2018, In : Gut. 67, 4, p. 719-727 9 p.

Research output: Contribution to journalArticle

17 Scopus citations

NFκB-mediated invasiveness in CD133 + pancreatic TICs is regulated by autocrine and paracrine activation of IL1 signaling

Nomura, A., Gupta, V. K., Dauer, P., Sharma, N. S., Dudeja, V., Merchant, N., Saluja, A. K. & Banerjee, S., Jan 2018, In : Molecular Cancer Research. 16, 1, p. 162-172 11 p.

Research output: Contribution to journalArticle

Open Access
13 Scopus citations
2017

Cannabis-Induced Acute Pancreatitis: A Systematic Review

Barkin, J. A., Nemeth, Z., Saluja, A. K. & Barkin, J. S., Sep 1 2017, In : Pancreas. 46, 8, p. 1035-1038 4 p.

Research output: Contribution to journalArticle

15 Scopus citations

Downregulation of Sp1 by Minnelide leads to decrease in HSP70 and decrease in tumor burden of Gastric cancer

Arora, N., Alsaied, O., Dauer, P., Majumder, K., Modi, S., Giri, B., Dudeja, V., Banerjee, S., Von Hoff, D. & Saluja, A., Feb 2017, In : PloS one. 12, 2, e0171827.

Research output: Contribution to journalArticle

Open Access
9 Scopus citations

Inhibition of hypoxic response decreases stemness and reduces tumorigenic signaling due to impaired assembly of HIF1 transcription complex in pancreatic cancer

McGinn, O., Gupta, V. K., Dauer, P., Arora, N., Sharma, N., Nomura, A., Dudeja, V., Saluja, A. & Banerjee, S., Dec 1 2017, In : Scientific reports. 7, 1, 7872.

Research output: Contribution to journalArticle

Open Access
7 Scopus citations

Inhibition of Sp1 prevents ER homeostasis and causes cell death by lysosomal membrane permeabilization in pancreatic cancer

Dauer, P., Gupta, V. K., McGinn, O., Nomura, A., Sharma, N. S., Arora, N., Giri, B., Dudeja, V., Saluja, A. K. & Banerjee, S., Dec 1 2017, In : Scientific reports. 7, 1, 1564.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations

Minnelide Inhibits Androgen Dependent, Castration Resistant Prostate Cancer Growth by Decreasing Expression of Androgen Receptor Full Length and Splice Variants

Isharwal, S., Modi, S., Arora, N., Uhlrich, C., Giri, B., Barlass, U., Soubra, A., Chugh, R., Dehm, S. M., Dudeja, V., Saluja, A., Banerjee, S. & Konety, B., May 1 2017, In : Prostate. 77, 6, p. 584-596 13 p.

Research output: Contribution to journalArticle

8 Scopus citations

Modulation of post-translational modifications in β-catenin and LRP6 inhibits Wnt signaling pathway in pancreatic cancer

Garg, B., Giri, B., Majumder, K., Dudeja, V., Banerjee, S. & Saluja, A., Mar 1 2017, In : Cancer Letters. 388, p. 64-72 9 p.

Research output: Contribution to journalArticle

18 Scopus citations

The 47th annual meeting of the American pancreatic association

Go, V. L. W., Fernandez, M. D., Carney, J. B. & Saluja, A. K., Jan 1 2017, In : Pancreas. 46, 6, p. 732-734 3 p.

Research output: Contribution to journalArticle

2016

American pancreatic association 2015 vay liang and frisca go award for lifetime achievement, APA distinguished service award, and other awardees

Go, V. L. W., Brudvik, E. A., Carney, J. B. & Saluja, A. K., Mar 4 2016, In : Pancreas. 45, 4, p. 489-492 4 p.

Research output: Contribution to journalArticle

1 Scopus citations

A Novel Immunocompetent Mouse Model of Pancreatic Cancer with Robust Stroma: a Valuable Tool for Preclinical Evaluation of New Therapies

Majumder, K., Arora, N., Modi, S., Chugh, R., Nomura, A., Giri, B., Dawra, R., Ramakrishnan, S., Banerjee, S., Saluja, A. & Dudeja, V., Jan 1 2016, In : Journal of Gastrointestinal Surgery. 20, 1, p. 53-65 13 p.

Research output: Contribution to journalArticle

12 Scopus citations

Chronic Pancreatitis in the 21st Century - Research Challenges and Opportunities

Uc, A., Andersen, D. K., Bellin, M. D., Bruce, J. I., Drewes, A. M., Engelhardt, J. F., Forsmark, C. E., Lerch, M. M., Lowe, M. E., Neuschwander-Tetri, B. A., O'Keefe, S. J., Palermo, T. M., Pasricha, P., Saluja, A. K., Singh, V. K., Szigethy, E. M., Whitcomb, D. C., Yadav, D. & Conwell, D. L., Nov 1 2016, In : Pancreas. 45, 10, p. 1365-1375 11 p.

Research output: Contribution to journalArticle

22 Scopus citations

Comprehensive analysis of microRNA signature of mouse pancreatic acini: Overexpression of miR-21-3p in acute pancreatitis

Dixit, A. K., Sarver, A. E., Yuan, Z., George, J., Barlass, U., Cheema, H., Sareen, A., Banerjee, S., Dudeja, V., Dawra, R., Subramanian, S. & Saluja, A. K., Jan 1 2016, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 311, 5, p. G974-G980

Research output: Contribution to journalArticle

Open Access
11 Scopus citations

Control of Apoptosis in Treatment and Biology of Pancreatic Cancer

Modi, S., Kir, D., Banerjee, S. & Saluja, A., Feb 1 2016, In : Journal of Cellular Biochemistry. 117, 2, p. 279-288 10 p.

Research output: Contribution to journalArticle

6 Scopus citations

Impaired synthesis of stromal components in response to minnelide improves vascular function, drug delivery, and survival in pancreatic cancer

Banerjee, S., Modi, S., McGinn, O., Zhao, X., Dudeja, V., Ramakrishnan, S. & Saluja, A. K., Jan 15 2016, In : Clinical Cancer Research. 22, 2, p. 415-425 11 p.

Research output: Contribution to journalArticle

Open Access
30 Scopus citations

Inhibition of NF-kappa B pathway leads to deregulation of epithelial-mesenchymal transition and neural invasion in pancreatic cancer

Nomura, A., Majumder, K., Giri, B., Dauer, P., Dudeja, V., Roy, S., Banerjee, S. & Saluja, A. K., Dec 1 2016, In : Laboratory Investigation. 96, 12, p. 1268-1278 11 p.

Research output: Contribution to journalArticle

26 Scopus citations

Microenvironment mediated alterations to metabolic pathways confer increased chemo-resistance in CD133+ tumor initiating cells

Nomura, A., Dauer, P., Gupta, V., McGinn, O., Arora, N., Majumdar, K., Uhlrich, C., Dalluge, J., Dudeja, V., Saluja, A. & Banerjee, S., Jan 1 2016, In : Oncotarget. 7, 35, p. 56324-56337 14 p.

Research output: Contribution to journalArticle

Open Access
20 Scopus citations

Minnelide Overcomes Oxaliplatin Resistance by Downregulating the DNA Repair Pathway in Pancreatic Cancer

Modi, S., Kir, D., Giri, B., Majumder, K., Arora, N., Dudeja, V., Banerjee, S. & Saluja, A. K., Jan 1 2016, In : Journal of Gastrointestinal Surgery. 20, 1, p. 13-24 12 p.

Research output: Contribution to journalArticle

13 Scopus citations

Release of Cathepsin B in Cytosol Causes Cell Death in Acute Pancreatitis

Talukdar, R., Sareen, A., Zhu, H., Yuan, Z., Dixit, A., Cheema, H., George, J., Barlass, U., Sah, R., Garg, S. K., Banerjee, S., Garg, P., Dudeja, V., Dawra, R. & Saluja, A. K., Oct 1 2016, In : Gastroenterology. 151, 4, p. 747-758.e5

Research output: Contribution to journalArticle

29 Scopus citations
2015

CD133 initiates tumors, induces epithelial-mesenchymal transition and increases metastasis in pancreatic cancer

Nomura, A., Banerjee, S., Chugh, R., Dudeja, V., Yamamoto, M., Vickers, S. M. & Saluja, A. K., Jan 1 2015, In : Oncotarget. 6, 10, p. 8313-8322 10 p.

Research output: Contribution to journalArticle

55 Scopus citations

Minnelide effectively eliminates CD133+ side population in pancreatic cancer

Nomura, A., McGinn, O., Dudeja, V., Sangwan, V., Saluja, A. K. & Banerjee, S., Nov 23 2015, In : Molecular Cancer. 14, 1, 200.

Research output: Contribution to journalArticle

14 Scopus citations

Minutes of the business meeting of the American pancreatic association, Friday, November 7, 2014, Kohala Coast, Hawaii

Pandol, S. J., Maitra, A., Freeman, M. L., Saluja, A. K., Conwell, D. L., Castillo, C. F. D., Sahin-Tóth, M. & Go, V. L. W., Jan 1 2015, In : Pancreas. 44, 8, p. 1176-1177 2 p.

Research output: Contribution to journalArticle

Primary and liver metastasis-derived cell lines from Kras G12D; Trp53 R172H; Pdx-1 cre animals undergo apoptosis in response to triptolide

Sangwan, V., Banerjee, S., Jensen, K. M., Chen, Z., Chugh, R., Dudeja, V., Vickers, S. M. & Saluja, A. K., May 25 2015, In : Pancreas. 44, 4, p. 583-589 7 p.

Research output: Contribution to journalArticle

16 Scopus citations

Targeting HSF1 disrupts HSP90 chaperone function in chronic lymphocytic leukemia

Ganguly, S., Home, T., Yacoub, A., Kambhampati, S., Shi, H., Dandawate, P., Padhye, S., Saluja, A. K., McGuirk, J. & Rao, R., Jan 1 2015, In : Oncotarget. 6, 31, p. 31767-31779 13 p.

Research output: Contribution to journalArticle

13 Scopus citations

Triptolide abrogates growth of colon cancer and induces cell cycle arrest by inhibiting transcriptional activation of E2F

Oliveira, A. R., Beyer, G., Chugh, R., Skube, S. J., Majumder, K., Banerjee, S., Sangwan, V., Li, L., Dawra, R. K., Subramanian, S., Saluja, A. K. & Dudeja, V., Jun 28 2015, In : Laboratory Investigation. 95, 6, p. 648-659 12 p.

Research output: Contribution to journalArticle

30 Scopus citations

Triptolide and its prodrug minnelide suppress Hsp70 and inhibit in vivo growth in a xenograft model of mesothelioma

Jacobson, B. A., Chen, E. Z., Tang, S., Belgum, H. S., McCauley, J. A., Evenson, K. A., Etchison, R. G., Jay-Dixon, J., Patel, M. R., Raza, A., Saluja, A. K., D’Cunha, J. & Kratzke, R. A., Jan 1 2015, In : Genes and Cancer. 6, 3-4, p. 144-152 9 p.

Research output: Contribution to journalArticle

13 Scopus citations

Triptolide enhances the tumoricidal activity of TRAIL against renal cell carcinoma

Brincks, E. L., Kucaba, T. A., James, B. R., Murphy, K. A., Schwertfeger, K. L., Sangwan, V., Banerjee, S., Saluja, A. K. & Griffith, T. S., Dec 1 2015, In : FEBS Journal. 282, 24, p. 4747-4765 19 p.

Research output: Contribution to journalArticle

11 Scopus citations
2014

CD133+ tumor initiating cells in a syngenic murine model of pancreatic cancer respond to minnelide

Banerjee, S., Nomura, A., Sangwan, V., Chugh, R., Dudeja, V., Vickers, S. M. & Saluja, A. K., May 1 2014, In : Clinical Cancer Research. 20, 9, p. 2388-2399 12 p.

Research output: Contribution to journalArticle

38 Scopus citations

Endoplasmic reticulum stress is chronically activated in chronic pancreatitis

Sah, R. P., Garg, S. K., Dixit, A. K., Dudeja, V., Dawra, R. K. & Saluja, A. K., Oct 3 2014, In : Journal of Biological Chemistry. 289, 40, p. 27551-27561 11 p.

Research output: Contribution to journalArticle

42 Scopus citations

Inhibition of epithelial ovarian cancer by Minnelide, a water-soluble pro-drug

Rivard, C., Geller, M. A., Schnettler, E., saluja, M., Vogel, R. I., Saluja, A. K. & Ramakrishnan, S., Nov 1 2014, In : Gynecologic oncology. 135, 2, p. 318-324 7 p.

Research output: Contribution to journalArticle

11 Scopus citations

Minutes of the business meeting of the American Pancreatic Association, Friday, November 1, 2013, Miami, Florida

Freeman, M., Pandol, S. J., Liddle, R. A., Saluja, A. K., Fernandez-Del Castillo, C., Maitra, A., Sahin-Toth, M. & Go, V. L. W., Nov 10 2014, In : Pancreas. 43, 8, p. 1141-1142 2 p.

Research output: Contribution to journalArticle

Sorafenib and triptolide as combination therapy for hepatocellular carcinoma

Alsaied, O., Sangwan, V., Banerjee, S., Krosch, T. C., Chugh, R., Saluja, A. K., Vickers, S. M. & Jensen, E. H., Aug 2014, In : Surgery (United States). 156, 2, p. 270-279 10 p.

Research output: Contribution to journalArticle

46 Scopus citations

Triptolide activates unfolded protein response leading to chronic ER stress in pancreatic cancer cells

Mujumdar, N., Banerjee, S., Chen, Z., Sangwan, V., Chugh, R., Dudeja, V., Yamamoto, M., Vickers, S. M. & Saluja, A. K., Jun 1 2014, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 306, 11, p. G1011-G1020

Research output: Contribution to journalArticle

31 Scopus citations

Triptolide sensitizes pancreatic cancer cells to TRAIL-induced activation of the Death Receptor pathway

Chen, Z., Sangwan, V., Banerjee, S., Chugh, R., Dudeja, V., Vickers, S. M. & Saluja, A. K., Jan 1 2014, In : Cancer Letters. 348, 1-2, p. 156-166 11 p.

Research output: Contribution to journalArticle

45 Scopus citations

Wild-type p53 reactivation by small-molecule Minnelide™ in human papillomavirus (HPV)-positive head and neck squamous cell carcinoma

Caicedo-Granados, E. E., Lin, R., Fujisawa, C., Yueh, B., Sangwan, V. & Saluja, A. K., Dec 1 2014, In : Oral Oncology. 50, 12, p. 1149-1156 8 p.

Research output: Contribution to journalArticle

9 Scopus citations
2013

Advances in acute and chronic pancreatitis: From development to inflammation and repair

Pasca Di Magliano, M., Forsmark, C., Freedman, S., Hebrok, M., Pasricha, P. J., Saluja, A., Stanger, B. Z., Holt, J., Serrano, J., James, S. P. & Rustgi, A. K., Jan 2013, In : Gastroenterology. 144, 1, p. e1-e4

Research output: Contribution to journalArticle

11 Scopus citations

Cerulein-induced chronic pancreatitis does not require intra-acinar activation of trypsinogen in mice

Sah, R. P., Dudeja, V., Dawra, R. K. & Saluja, A. K., May 2013, In : Gastroenterology. 144, 5, p. 1076-1085.e2

Research output: Contribution to journalArticle

54 Scopus citations

Minnelide: A Novel Therapeutic That Promotes Apoptosis in Non-Small Cell Lung Carcinoma In Vivo

Rousalova, I., Banerjee, S., Sangwan, V., Evenson, K., McCauley, J. A., Kratzke, R., Vickers, S. M., Saluja, A. & D'Cunha, J., Oct 15 2013, In : PloS one. 8, 10, e77411.

Research output: Contribution to journalArticle

33 Scopus citations

Minnelide reduces tumor burden in preclinical models of osteosarcoma

Banerjee, S., Thayanithy, V., Sangwan, V., Mackenzie, T. N., Saluja, A. K. & Subramanian, S., Jul 28 2013, In : Cancer Letters. 335, 2, p. 412-420 9 p.

Research output: Contribution to journalArticle

40 Scopus citations

Minutes of the business meeting of the American Pancreatic Association, Friday, November 2, 2012, Miami, Florida.

Liddle, R. A., Freeman, M., Simeone, D. M., Saluja, A. K., Castillo, C. F. D., Maitra, A., Pandol, S. J. & Go, V. L. W., Nov 1 2013, In : Pancreas. 42, 8, p. 1333-1334 2 p.

Research output: Contribution to journalArticle

MiR-204 mediated loss of Myeloid cell leukemia-1 results in pancreatic cancer cell death

Chen, Z., Sangwan, V., Banerjee, S., Mackenzie, T., Dudeja, V., Li, X., Wang, H., Vickers, S. M. & Saluja, A. K., Sep 11 2013, In : Molecular Cancer. 12, 1, 105.

Research output: Contribution to journalArticle

46 Scopus citations

Relevance of animal models of pancreatic cancer and pancreatitis to human disease

Saluja, A. K. & Dudeja, V., Jun 2013, In : Gastroenterology. 144, 6, p. 1194-1198 5 p.

Research output: Contribution to journalArticle

30 Scopus citations

Triptolide-induced cell death in Pancreatic cancer is mediated by O-GlcNAc modification of transcription factor Sp1

Banerjee, S., Sangwan, V., McGinn, O., Chugh, R., Dudeja, V., Vickers, S. M. & Saluja, A. K., Nov 22 2013, In : Journal of Biological Chemistry. 288, 47, p. 33927-33938 12 p.

Research output: Contribution to journalArticle

Triptolide induces the expression of miR-142-3p: A negative regulator of heat shock protein 70 and pancreatic cancer cell proliferation

MacKenzie, T. N., Mujumdar, N., Banerjee, S., Sangwan, V., Sarver, A., Vickers, S., Subramanian, S. & Saluja, A. K., Jul 1 2013, In : Molecular Cancer Therapeutics. 12, 7, p. 1266-1275 10 p.

Research output: Contribution to journalArticle

84 Scopus citations

Triptolide-mediated cell death in neuroblastoma occurs by both apoptosis and autophagy pathways and results in inhibition of nuclear factor-kappa B activity

Krosch, T. C. K., Sangwan, V., Banerjee, S., Mujumdar, N., Dudeja, V., Saluja, A. K. & Vickers, S. M., Apr 1 2013, In : American Journal of Surgery. 205, 4, p. 387-396 10 p.

Research output: Contribution to journalArticle

38 Scopus citations
2012

A preclinical evaluation of minnelide as a therapeutic agent against pancreatic cancer

Chugh, R., Sangwan, V., Patil, S. P., Dudeja, V., Dawra, R. K., Banerjee, S., Schumacher, R. J., Blazar, B. R., Georg, G. I., Vickers, S. M. & Saluja, A. K., Oct 17 2012, In : Science Translational Medicine. 4, 156, 156ra139.

Research output: Contribution to journalArticle

160 Scopus citations

MUC1c regulates cell survival in pancreatic cancer by preventing lysosomal permeabilization

Banerjee, S., Mujumdar, N., Dudeja, V., Mackenzie, T., Krosch, T. K., Sangwan, V., Vickers, S. M. & Saluja, A. K., Aug 13 2012, In : PloS one. 7, 8, e43020.

Research output: Contribution to journalArticle

14 Scopus citations
2011

Insulin degradation by acinar cell proteases creates a dysfunctional environment for human islets before/after transplantation: Benefits of α-1 antitrypsin treatment

Loganathan, G., Dawra, R. K., Pugazhenthi, S., Guo, Z., Soltani, S. M., Wiseman, A., Sanders, M. A., Papas, K. K., Velayutham, K., Saluja, A. K., Sutherland, D. E. R., Hering, B. J. & Balamurugan, A. N., Dec 15 2011, In : Transplantation. 92, 11, p. 1222-1230 9 p.

Research output: Contribution to journalArticle

22 Scopus citations

Intra-acinar trypsinogen activation mediates early stages of pancreatic injury but not inflammation in mice with acute pancreatitis

Dawra, R. K., Sah, R. P., Dudeja, V., Rishi, L., Talukdar, R., Garg, P. & Saluja, A. K., Dec 2011, In : Gastroenterology. 141, 6, p. 2210-2217.e2

Research output: Contribution to journalArticle

131 Scopus citations

Myricetin induces pancreatic cancer cell death via the induction of apoptosis and inhibition of the phosphatidylinositol 3-kinase (PI3K) signaling pathway

Phillips, P. A., Sangwan, V., Borja-Cacho, D., Dudeja, V., Vickers, S. M. & Saluja, A. K., Sep 28 2011, In : Cancer Letters. 308, 2, p. 181-188 8 p.

Research output: Contribution to journalArticle

74 Scopus citations