Projects per year
Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Collaborations and top research areas from the last five years
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Discovery and validation of single cell biomarkers for clinical outcome in sickle cell disease
Wood, D. K. (PI), Datta, Y. H. (CoI), Gupta, A. O. (CoI) & Vercellotti, G. M. (CoI)
NIH NAT'L HEART, LUNG, AND BLOOD INSTITU
12/15/24 → 11/30/25
Project: Research project
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GenoKrabbe: A Comprehensive Genotype-Phenotype Database for Krabbe Disease
Orchard, P. J. (PI), Gupta, A. O. (CoI), Pillai, N. (CoI), Braun, J. A. (Other Role) & Shanley, R. M. (Other Role)
ROSENAU FAMILY RESEARCH FOUNDATION
11/1/24 → 10/31/27
Project: Research project
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A multi-center, randomized, active controlled clinical trial to evaluate the efficacy and safety of OTL-203 in subjects with mucopolysaccharidosis type I, Hurler syndrome (MPS-IH) compared to standard of care with allogeneic hematopoietic stem cell trans
Gupta, A. O. (PI)
8/14/23 → 8/30/33
Project: Research project
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Collection of Gene Mutations for Laboratory Quality Assurance: Newborn Screening Accuracy Project
Gupta, A. O. (PI) & Pillai, N. (CoI)
SEQUOIA FOUNDATION, CENTERS FOR DISEASE CONTROL & PREVENTION
5/15/23 → 5/14/28
Project: Research project
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Insights From Minnesota on Newborn Screening for Adrenoleukodystrophy: A 5-Year Update
Rayannavar, A., Billington, C. J., Tryon, R., Kaye, T., Gupta, A. O., Lund, T. C., Lteif, A., Adriatico, K., Orchard, P. J., Miller, B. S. & Pillai, N. R., 2025, (Accepted/In press) In: American Journal of Medical Genetics, Part A.Research output: Contribution to journal › Article › peer-review
Open Access -
Developmental delay can precede neurologic regression in early onset metachromatic leukodystrophy
Adang, L. A., Groeschel, S., Grzyb, C., D'Aiello, R., Gavazzi, F., Sherbini, O., Bronner, N., Patel, A., Vincent, A., Sevagamoorthy, A., Mutua, S., Muirhead, K., Schmidt, J., Pizzino, A., Yu, E., Jin, D., Eichler, F., Fraser, J. L., Emrick, L. & Van Haren, K. & 28 others, , Aug 2024, In: Molecular Genetics and Metabolism. 142, 4, 108521.Research output: Contribution to journal › Article › peer-review
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Diffusion Tensor Imaging in Boys with Adrenoleukodystrophy: Identification of Cerebral Disease and Association with Neurocognitive Outcomes
Pierpont, E. I., Labounek, R., Gupta, A., Lund, T., Orchard, P. J., Dobyns, W. B., Bondy, M., Paulson, A., Metz, A., Shanley, R., Wozniak, J. R., Mueller, B. A., Loes, D., Nascene, D. & Nestrasil, I., Aug 16 2024, In: Neurology. 103, 5, e209764.Research output: Contribution to journal › Article › peer-review
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Hematologic Cancer after Gene Therapy for Cerebral Adrenoleukodystrophy
Duncan, C. N., Bledsoe, J. R., Grzywacz, B. J., Beckman, A., Bonner, M., Eichler, F. S., Kühl, J. S., Harris, M. H., Slauson, S., Colvin, R. A., Prasad, V. K., Downey, G. F., Pierciey, F. J., Kinney, M. A., Foos, M., Lodaya, A., Floro, N., Parsons, G., Dietz, A. C. & Gupta, A. O. & 3 others, , Oct 10 2024, In: New England Journal of Medicine. 391, 14, p. 1287-1301 15 p.Research output: Contribution to journal › Article › peer-review
13 Scopus citations -
International Society for Cell & Gene Therapy Stem Cell Engineering Committee report on the current state of hematopoietic stem and progenitor cell–based genomic therapies and the challenges faced
Gupta, A. O., Azul, M., Bhoopalan, S. V., Abraham, A., Bertaina, A., Bidgoli, A., Bonfim, C., DeZern, A., Li, J., Louis, C. U., Purtill, D., Ruggeri, A., Boelens, J. J., Prockop, S. & Sharma, A., Nov 2024, In: Cytotherapy. 26, 11, p. 1411-1420 10 p.Research output: Contribution to journal › Article › peer-review
2 Scopus citations