Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
-
SDG 3 Good Health and Well-being
Fingerprint
- 1 Similar Profiles
Collaborations and top research areas from the last five years
-
A novel approach to restore functional TDP43 for the treatment of FTD and ALS
Sachs, J. N. (PI), Braun, A. R. (CoI), Chen, L. (CoI), Dutton, J. R. (CoI) & Nathan Kochen, N. (Graduate Student)
NIH NATIONAL INSTITUTE ON AGING
5/1/25 → 4/30/27
Project: Research project
-
Advanced multiplexing technologies with innovative Dual-Channel Dark-FRET biosensors for dynamic monitoring of alpha-synuclein pathophysiology: From cellular to in vivo models
Sachs, J. N. (PI), Braun, A. R. (Co-Principal Investigator), Chen, L. (Co-Principal Investigator) & Dutton, J. R. (Co-Principal Investigator)
NATIONAL INSTITUTES OF HEALTH (NIH)
7/15/24 → 4/30/26
Project: Research project
-
Understanding the remodeling of lipid bilayers induced b
Braun, A. R. (PI), Lee, M. K. (CoI), Sachs, J. N. (CoI) & Thomas, D. D. (CoI)
NATIONAL INSTITUTES OF HEALTH (NIH)
5/29/12 → 7/31/14
Project: Research project
-
Fluorescence Lifetime-Based FRET Biosensors for Monitoring N Terminal Domain-Dependent Interactions of TDP-43 in Living Cells: A Novel Approach for ALS and FTD Drug Discovery
Nathan Kochen, N., Murray, M., Zafari, S., Vunnam, N., Liao, E. E., Chen, L., Braun, A. R. & Sachs, J. N., Jul 2 2025, In: ACS Chemical Neuroscience. 16, 13, p. 2450-2462 13 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Link opens in a new tab Scopus citations -
Post-translational modification sites are present in hydrophilic cavities of alpha-synuclein, tau, FUS, and TDP-43 fibrils: A molecular dynamics study
Kochen, N. N., Seaney, D., Vasandani, V., Murray, M., Braun, A. R. & Sachs, J. N., Jul 2024, In: Proteins: Structure, Function and Bioinformatics. 92, 7, p. 854-864 11 p.Research output: Contribution to journal › Article › peer-review
Open Access2 Link opens in a new tab Scopus citations -
Advancements in a FRET Biosensor for Live-Cell Fluorescence-Lifetime High-Throughput Screening of Alpha-Synuclein
Braun, A. R., Kochen, N. N., Yuen, S. L., Liao, E. E., Cornea, R. L., Thomas, D. D. & Sachs, J. N., Jan 1 2023, In: ASN Neuro. 15Research output: Contribution to journal › Article › peer-review
Open Access7 Link opens in a new tab Scopus citations -
pH Effects Can Dominate Chemical Shift Perturbations in 1H,15N-HSQC NMR Spectroscopy for Studies of Small Molecule/α-Synuclein Interactions
Pandey, A. K., Buchholz, C. R., Nathan Kochen, N., Pomerantz, W. C. K., Braun, A. R. & Sachs, J. N., Feb 15 2023, In: ACS Chemical Neuroscience. 14, 4, p. 800-808 9 p.Research output: Contribution to journal › Article › peer-review
Open Access10 Link opens in a new tab Scopus citations -
Proteasomal Stimulation by MK886 and Its Derivatives Can Rescue Tau-Induced Neurite Pathology
Liao, E. E., Yang, M., Nathan Kochen, N., Vunnam, N., Braun, A. R., Ferguson, D. M. & Sachs, J. N., Oct 2023, In: Molecular neurobiology. 60, 10, p. 6133-6144 12 p.Research output: Contribution to journal › Article › peer-review
Open Access10 Link opens in a new tab Scopus citations