Projects per year
Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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SDG 9 Industry, Innovation, and Infrastructure
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- 10 Similar Profiles
Collaborations and top research areas from the last five years
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Multiplex engineered gamma delta T cells for systemic correction of dystrophic epidermolysis bullosa
Webber, B. R. (PI), Ebens, C. (CoI), McKenna, D. H. (CoI), DeFeo, A. P. (Other Role), Johnson, R. A. (Other Role) & Stelljes, E. (Other Role)
8/1/26 → 7/31/30
Project: Research project
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Gene-edited tumor infiltrating lymphocytes for ovarian cancer immunotherapy
Webber, B. R. (PI) & DeFeo, A. P. (Other Role)
MINNESOTA OVARIAN CANCER ALLIANCE
5/1/26 → 4/30/27
Project: Research project
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NKG7-armed tumor infiltrating lymphocyte therapy for metastatic uveal melanoma; Project 2 - Develop engineering strategy and tech transfer support
Webber, B. R. (PI), Moriarity, B. S. (CoI), DeFeo, A. P. (Other Role), Gupta, P. (Other Role) & Johnson, M. J. (Other Role)
MAYO CLINIC ROCHESTER, U.S. DEPARTMENT OF DEFENSE
9/1/25 → 8/31/29
Project: Research project
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Gene-edited tumor infiltrating lymphocytes for ovarian cancer immunotherapy
Webber, B. R. (PI) & DeFeo, A. P. (Other Role)
MINNESOTA OVARIAN CANCER ALLIANCE
7/1/24 → 6/30/26
Project: Research project
Research output
- 14 Article
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Clinical manufacture of CRISPR/Cas9-based cytokine-induced SH2 protein knock-out tumor-infiltrating lymphocytes for gastrointestinal cancers
Johnson, M. J., Sumstad, D., Folsom, T. D., Slipek, N. J., DeFeo, A. P., Growe, M., Kadidlo, D., Thyagarajan, B., Starr, T. K., Lou, E., Choudhry, M., Moriarity, B. S., Webber, B. R. & McKenna, D. H., Oct 2025, In: Cytotherapy. 27, 10, p. 1229-1239 11 p.Research output: Contribution to journal › Article › peer-review
5 Link opens in a new tab Scopus citations -
Non-Viral Engineering of Primary Human T Cells via Homology-Mediated End-Joining Targeted Integration of Large DNA Templates
Johnson, M. J., Defeo, A. P., Slipek, N. J., Folsom, T. D., Henley, T., Choudhry, M. S., Webber, B. R. & Moriarity, B. S., May 2025, In: Journal of Visualized Experiments. 2025-May, 219, e68150.Research output: Contribution to journal › Article › peer-review
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Targeting the intracellular immune checkpoint CISH with CRISPR-Cas9-edited T cells in patients with metastatic colorectal cancer: a first-in-human, single-centre, phase 1 trial
Lou, E., Choudhry, M. S., Starr, T., Folsom, T. D., Bell, J. B., Rathmann, B., DeFeo, A. P., Kim, J., Slipek, N. J., Jin, Z., Sumstad, D., Klebanoff, C. A., Ladner, K., Sarkari, A., McIvor, R. S., Murray, T. A., Miller, J. S., Rao, M., Jensen, E. & Ankeny, J. & 13 others, , May 2025, In: The Lancet Oncology. 26, 5, p. 559-570 12 p.Research output: Contribution to journal › Article › peer-review
48 Link opens in a new tab Scopus citations -
Cas9-induced targeted integration of large DNA payloads in primary human T cells via homology-mediated end-joining DNA repair
Webber, B. R., Johnson, M. J., Skeate, J. G., Slipek, N. J., Lahr, W. S., DeFeo, A. P., Mills, L. J., Qiu, X., Rathmann, B., Diers, M. D., Wick, B., Henley, T., Choudhry, M., Starr, T. K., McIvor, R. S. & Moriarity, B. S., Dec 2024, In: Nature Biomedical Engineering. 8, 12, p. 1553-1570 18 p., 5222.Research output: Contribution to journal › Article › peer-review
Open Access20 Link opens in a new tab Scopus citations -
Correction of Fanconi Anemia Mutations Using Digital Genome Engineering
Sipe, C. J., Kluesner, M. G., Bingea, S. P., Lahr, W. S., Andrew, A. A., Wang, M., DeFeo, A. P., Hinkel, T. L., Laoharawee, K., Wagner, J. E., MacMillan, M. L., Vercellotti, G. M., Tolar, J., Osborn, M. J., McIvor, R. S., Webber, B. R. & Moriarity, B. S., Aug 2022, In: International journal of molecular sciences. 23, 15, 8416.Research output: Contribution to journal › Article › peer-review
Open Access14 Link opens in a new tab Scopus citations