Projects per year
Personal profile
Research interests
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Research Interest Keywords
- drug discovery
- microbial genetics
- metabolomics
- tuberculosis
- microbiology
- drug mechanism
- metabolism
- drug resistance
- tb
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Collaborations and top research areas from the last five years
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Targeting trans-translation to kill M. tuberculosis non-replicating persistent cells
Baughn, A. (PI), Jia, Z. (Other Role), Rather, M. A. (Other Role) & Schacht, N. A. (Other Role)
THE UNIVERSITY OF TEXAS AT AUSTIN, NATIONAL INSTITUTES OF HEALTH (NIH)
11/1/24 → 10/31/26
Project: Research project
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Biomimetic Peptide Aerosols for Rapid Clearance of Pulmonary MDR Tuberculosis
Baughn, A. (PI)
PENNSYLVANIA STATE UNIVERSITY, NATIONAL INSTITUTES OF HEALTH (NIH)
11/19/21 → 10/31/25
Project: Research project
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The impact of pyrazinamide on metabolism in Mycobacterium tuberculosis
Baughn, A. (PI)
NIH Nat'l Inst of Allergy & Infect Dis
3/10/21 → 2/28/26
Project: Research project
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Targeting trans-translation to kill M. tuberculosis non-replicating persistent cells
Baughn, A. (PI)
PENNSYLVANIA STATE UNIVERSITY, NATIONAL INSTITUTES OF HEALTH (NIH)
11/1/21 → 4/30/24
Project: Research project
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Identification of novel dual-acting bactericidal drug targets for tuberculosis treatment
Baughn, A. (PI) & Aldrich, C. (CoI)
FUJITA HEALTH UNIVERSITY, GLOBAL HEALTH INNOVATIVE TECHNOLOGY FUND
7/6/21 → 1/31/25
Project: Research project
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A trans-Translation Inhibitor is Potentiated by Zinc and Kills Mycobacterium tuberculosis and Nontuberculous Mycobacteria
Varshney, A., Jia, Z., Howe, M. D., Keiler, K. C. & Baughn, A. D., May 9 2025, In: ACS Infectious Diseases. 11, 5, p. 1140-1152 13 p.Research output: Contribution to journal › Article › peer-review
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Lead Informed Artificial Intelligence Mining of Antitubercular Host Defense Peptides
Biswas, D., Benson, S., Matunis, A., Gebretsadik, G., Wertz, A., StPierre, B. J., Schacht, N., Yan, Y., Gebremichael, H. Y., Wong, P. K., Baughn, A. D. & Medina, S. H., May 12 2025, In: Biomacromolecules. 26, 5, p. 3167-3179 13 p.Research output: Contribution to journal › Article › peer-review
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A Nucleophilic Activity-Based Probe Enables Profiling of PLP-Dependent Enzymes
Brody, S. I., Buonomo, J. A., Orimoloye, M. O., Jia, Z., Sharma, S., Brown, C. D., Baughn, A. D. & Aldrich, C. C., Apr 3 2023, In: ChemBioChem. 24, 7, e202200669.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Unique genomic sequences in a novel Mycobacterium avium subsp. hominissuis lineage enable fine scale transmission route tracing during pig movement
Komatsu, T., Ohya, K., Ota, A., Nishiuchi, Y., Yano, H., Matsuo, K., Odoi, J. O., Suganuma, S., Sawai, K., Hasebe, A., Asai, T., Yanai, T., Fukushi, H., Wada, T., Yoshida, S., Ito, T., Arikawa, K., Kawai, M., Ato, M. & Baughn, A. D. & 2 others, , Jun 2023, In: One Health. 16, 100559.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Cephem-Pyrazinoic Acid Conjugates: Circumventing Resistance in Mycobacterium tuberculosis
Cole, M. S., Howe, M. D., Buonomo, J. A., Sharma, S., Lamont, E. A., Brody, S. I., Mishra, N. K., Minato, Y., Thiede, J. M., Baughn, A. D. & Aldrich, C. C., Sep 12 2022, In: Chemistry - A European Journal. 28, 51, e202200995.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations
Datasets
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TnSeq of Himar1 transposon library of Mycobacterium tuberculosis H37Rv grown in vitro (on Mtb YM rich or Mtb minimal).
Minato, Y. & Baughn, A., Data Repository for the University of Minnesota, 2019
DOI: 10.13020/c37f-nv41, http://hdl.handle.net/11299/203632
Dataset