Projects per year
Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Research Interest Keywords
- Aneuploidy, Polyploidy, Genome Plasticity, Antifungal Drug Resistance, Rates of Adaptive Evolution
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Collaborations and top research areas from the last five years
Projects
- 5 Active
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Polyploidy: Integration across scales and biological systems
Selmecki, A. M. (PI)
UNIVERSITY OF FLORIDA, THE NATIONAL SCIENCE FOUNDATION
6/1/24 → 5/31/30
Project: Research project
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An Interdisciplinary Training Program to Transform Graduate Education In Genetics and Genomics
Greenstein, D. I. (PI), Albert, F. W. (CoI), O'Connor, M. B. (CoI) & Selmecki, A. M. (CoI)
NIH NIGMS NATL INST OF GENERAL
7/1/21 → 6/30/26
Project: Research project
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Genome Plasticity in Fungal Adaptation and Pathogenesis
Selmecki, A. M. (PI)
11/1/20 → 10/31/27
Project: Research project
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Genomic Research Capacity Building for Cryptococcosis Translational Studies
Nielsen, K. (PI) & Selmecki, A. M. (CoI)
NIH NAT INST OF NEURO DISORDERS & STROKE
9/1/20 → 7/31/25
Project: Research project
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Aneuploidy and Acquired Antifungal Drug Resistance in Candida species
Selmecki, A. M. (PI)
NIH Nat'l Inst of Allergy & Infect Dis
12/1/19 → 11/30/25
Project: Research project
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Addendum: A small molecule produced by Lactobacillus species blocks Candida albicans filamentation by inhibiting a DYRK1-family kinase
MacAlpine, J., Daniel-Ivad, M., Liu, Z., Yano, J., Revie, N. M., Todd, R. T., Stogios, P. J., Sanchez, H., O'Meara, T. R., Tompkins, T. A., Savchenko, A., Selmecki, A., Veri, A. O., Andes, D. R., Fidel, P. L., Robbins, N., Nodwell, J., Whitesell, L. & Cowen, L. E., Aug 1 2024, In: Nature communications. 15, 1, p. 6440 1 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Aneuploidy Can Be an Evolutionary Diversion on the Path to Adaptation
Kohanovski, I., Pontz, M., Zande, P. V., Selmecki, A., Dahan, O., Pilpel, Y., Yona, A. H. & Ram, Y., Mar 1 2024, In: Molecular biology and evolution. 41, 3, msae052.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Erg251 has complex and pleiotropic effects on sterol composition, azole susceptibility, filamentation, and stress response phenotypes
Zhou, X., Hilk, A., Solis, N. V., Pereira De Sa, N., Hogan, B. M., Bierbaum, T. A., Del Poeta, M., Filler, S. G., Burrack, L. S. & Selmecki, A., Jul 2024, In: PLoS pathogens. 20, 7, e1012389.Research output: Contribution to journal › Article › peer-review
Open Access -
Single-cell detection of copy number changes reveals dynamic mechanisms of adaptation to antifungals in Candida albicans
Zhou, X., Hilk, A., Solis, N. V., Scott, N., Beach, A., Soisangwan, N., Billings, C. L., Burrack, L. S., Filler, S. G. & Selmecki, A., Nov 2024, In: Nature Microbiology. 9, 11, p. 2923-2938 16 p.Research output: Contribution to journal › Article › peer-review
2 Scopus citations -
Step-wise evolution of azole resistance through copy number variation followed by KSR1 loss of heterozygosity in Candida albicans
Zande, P. V., Gautier, C., Kawar, N., Maufrais, C., Metzner, K., Wash, E., Beach, A. K., Bracken, R., Maciel, E. I., de Sá, N. P., Fernandes, C. M., Solis, N. V., Del Poeta, M., Filler, S. G., Berman, J., Ene, I. V. & Selmecki, A., Aug 2024, In: PLoS pathogens. 20, 8 August, e1012497.Research output: Contribution to journal › Article › peer-review
Open Access
Datasets
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De novo assemblies for the manuscrip "Candida albicans isolates contain frequent heterozygous structural variants and transposable elements within genes and centromeres"
Selmecki, A. M., Ursula, O., Todd, R. T., Soisangwan, N., Kemp, B., Guyer, A. & Beach, A., ZENODO, Jun 12 2024
DOI: 10.5281/zenodo.11623082, https://zenodo.org/records/11623082
Dataset