Research Output per year
Research Output 2006 2018
Article
93
Citations
(Scopus)
CYP2B6 Genotype Alters Abstinence Rates in a Bupropion Smoking Cessation Trial
Lee, A. M., Jepson, C., Hoffmann, E., Epstein, L., Hawk, L. W., Lerman, C. & Tyndale, R. F., Sep 15 2007, In : Biological Psychiatry. 62, 6, p. 635-641 7 p.Research output: Contribution to journal › Article
Bupropion
Smoking Cessation
Genotype
Placebos
Therapeutics
35
Citations
(Scopus)
CYP2B6 genotype does not alter nicotine metabolism, plasma levels, or abstinence with nicotine replacement therapy
Lee, A. M., Jepson, C., Shields, P. G., Benowitz, N., Lerman, C. & Tyndale, R. F., Jun 1 2007, In : Cancer Epidemiology Biomarkers and Prevention. 16, 6, p. 1312-1314 3 p.Research output: Contribution to journal › Article
N Demethylating Oxidoreductases
Inhalation Administration
Nicotinic Agonists
Cutaneous Administration
Aryl Hydrocarbon Hydroxylases
36
Citations
(Scopus)
CYP2B6 is expressed in African Green monkey brain and is induced by chronic nicotine treatment
Lee, A. M., Miksys, S., Palmour, R. & Tyndale, R. F., Mar 1 2006, In : Neuropharmacology. 50, 4, p. 441-450 10 p.Research output: Contribution to journal › Article
Cercopithecus aethiops
Nicotine
Brain
Haplorhini
Bupropion
11
Citations
(Scopus)
Deletion of Prkcz Increases Intermittent Ethanol Consumption in Mice
Lee, A. M., Zou, M. E., Lim, J. P., Stecher, J., Mcmahon, T. & Messing, R. O., Jan 1 2014, In : Alcoholism: Clinical and Experimental Research. 38, 1, p. 170-178 9 p.Research output: Contribution to journal › Article
Protein Kinase C
Ethanol
Drinking
Proteins
PC12 Cells
55
Citations
(Scopus)
Induction of the drug metabolizing enzyme CYP2D in monkey brain by chronic nicotine treatment
Mann, A., Miksys, S., Lee, A., Mash, D. C. & Tyndale, R. F., Dec 1 2008, In : Neuropharmacology. 55, 7, p. 1147-1155 9 p.Research output: Contribution to journal › Article
Nicotine
Haplorhini
Cytochrome P-450 CYP2D6
Brain
Enzymes
19
Citations
(Scopus)
In vivo and in vitro characterization of chlorzoxazone metabolism and hepatic CYP2E1 levels in African green monkeys: Induction by chronic nicotine treatment
Lee, A. M., Yue, J. & Tyndale, R. F., Aug 31 2006, In : Drug Metabolism and Disposition. 34, 9, p. 1508-1515 8 p.Research output: Contribution to journal › Article
Chlorzoxazone
Cercopithecus aethiops
Cytochrome P-450 CYP2E1
Nicotine
Metabolism
3
Citations
(Scopus)
Novel Small-Molecule Inhibitors of Protein Kinase C Epsilon Reduce Ethanol Consumption in Mice
Blasio, A., Wang, J., Wang, D., Varodayan, F. P., Pomrenze, M. B., Miller, J., Lee, A. M., McMahon, T., Gyawali, S., Wang, H. Y., Roberto, M., McHardy, S., Pleiss, M. A. & Messing, R. O., Aug 1 2018, In : Biological Psychiatry. 84, 3, p. 193-201 9 p.Research output: Contribution to journal › Article
Open Access
Protein Kinase C-epsilon
Ethanol
Alcohol Drinking
Sucrose
Phosphotransferases
16
Citations
(Scopus)
Phenobarbital increases monkey in vivo nicotine disposition and induces liver and brain CYP2B6 protein
Lee, A. M., Miksys, S. & Tyndale, R. F., Jul 22 2006, In : British Journal of Pharmacology. 148, 6, p. 786-794 9 p.Research output: Contribution to journal › Article
Phenobarbital
Nicotine
Haplorhini
Liver
Brain
9
Citations
(Scopus)
Phenobarbital induces monkey brain CYP2E1 protein but not hepatic CYP2E1, in vitro or in vivo chlorzoxazone metabolism
Lee, A. M., Joshi, M., Yue, J. & Tyndale, R. F., Dec 15 2006, In : European Journal of Pharmacology. 552, 1-3, p. 151-158 8 p.Research output: Contribution to journal › Article
Chlorzoxazone
Cytochrome P-450 CYP2E1
Phenobarbital
Haplorhini
Liver
9
Citations
(Scopus)
PKCε phosphorylates α4β2 nicotinic ACh receptors and promotes recovery from desensitization
Lee, A. M., Wu, D. F., Dadgar, J., Wang, D., McMahon, T. & Messing, R. O., Sep 1 2015, In : British Journal of Pharmacology. 172, 17, p. 4430-4441 12 p.Research output: Contribution to journal › Article
Nicotinic Receptors
Cholinergic Receptors
Phosphorylation
Induced Hypothermia
Synaptosomes
157
Citations
(Scopus)
Prkcz null mice show normal learning and memory
Lee, A. M., Kanter, B. R., Wang, D., Lim, J. P., Zou, M. E., Qiu, C., McMahon, T., Dadgar, J., Fischbach-Weiss, S. C. & Messing, R. O., Jan 17 2013, In : Nature. 493, 7432, p. 416-419 4 p.Research output: Contribution to journal › Article
Protein Kinase C
Learning
Peptides
Cocaine
Long-Term Memory
17
Citations
(Scopus)
Protein kinase C epsilon modulates nicotine consumption and dopamine reward signals in the nucleus accumbens
Lee, A. M. & Messing, R. O., Oct 20 2011, In : Proceedings of the National Academy of Sciences of the United States of America. 108, 38, p. 16080-16085 6 p.Research output: Contribution to journal › Article
Protein Kinase C-epsilon
Nucleus Accumbens
Nicotine
Reward
Dopamine
1
Citation
(Scopus)
The nicotinic receptor drug sazetidine-A reduces alcohol consumption in mice without affecting concurrent nicotine consumption
Touchette, J. C., Maertens, J. J., Mason, M. M., O'Rourke, K. Y. & Lee, A. M., May 1 2018, In : Neuropharmacology. 133, p. 63-74 12 p.Research output: Contribution to journal › Article
Nicotinic Receptors
Nicotine
Alcohol Drinking
Pharmaceutical Preparations
Alcohols
5
Citations
(Scopus)
Voluntary co-consumption of alcohol and nicotine: Effects of abstinence, intermittency, and withdrawal in mice
O'Rourke, K. Y., Touchette, J. C., Hartell, E. C., Bade, E. J. & Lee, A. M., Oct 1 2016, In : Neuropharmacology. 109, p. 236-246 11 p.Research output: Contribution to journal › Article
Nicotine
Alcohol Drinking
Alcohols
Alcohol Abstinence
Pharmaceutical Preparations