Ann M Bode

1990 …2020
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Research Output 1990 2020

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Article
2020

Trichothecin inhibits invasion and metastasis of colon carcinoma associating with SCD-1-mediated metabolite alteration

Liao, C., Li, M., Li, X., Li, N., Zhao, X., Wang, X., Song, Y., Quan, J., Cheng, C., Liu, J., Bode, A. M., Cao, Y. & Luo, X., Feb 2020, In : Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids. 1865, 2, 158540.

Research output: Contribution to journalArticle

Open Access
Stearoyl-CoA Desaturase
Colon
Neoplasm Metastasis
Carcinoma
Neoplasms
2019

3,3’-Diindolylmethane inhibits patient-derived xenograft colon tumor growth by targeting COX1/2 and ERK1/2

Tian, X., Liu, K. D., Zu, X., Ma, F., Li, Z., Lee, M. H., Chen, H., Li, Y., Zhao, Y., Liu, F., Oi, N., Bode, A. M., Dong, Z. & Kim, D. J., Apr 28 2019, In : Cancer Letters. 448, p. 20-30 11 p.

Research output: Contribution to journalArticle

Heterografts
Colon
Growth
Neoplasms
Colonic Neoplasms
Peptides
Membranes
Pharmaceutical Preparations
Amino Acids
Intracellular Membranes

Aurora B kinase as a novel molecular target for inhibition the growth of osteosarcoma

Zhao, Z., Jin, G., Yao, K., Liu, K., Liu, F., Chen, H., Wang, K., Gorja, D. R., Kanamata Reddy, S. R., Bode, A. M., Guo, Z. & Dong, Z., Jun 2019, In : Molecular Carcinogenesis. 58, 6, p. 1056-1067 12 p.

Research output: Contribution to journalArticle

Aurora Kinase B
Osteosarcoma
Growth
Heterografts
Tissue Array Analysis
2 Citations (Scopus)

Cell growth inhibition by 3-deoxysappanchalcone is mediated by directly targeting the TOPK signaling pathway in colon cancer

Zhao, R., Huang, H., Choi, B. Y., Liu, X., Zhang, M., Zhou, S., Song, M., Yin, F., Chen, H., Shim, J. H., Bode, A. M., Dong, Z. & Lee, M. H., Aug 2019, In : Phytomedicine. 61, 152813.

Research output: Contribution to journalArticle

Colonic Neoplasms
Growth
Phosphotransferases
Caesalpinia
Cell Proliferation
1 Citation (Scopus)

EBV(LMP1)-induced metabolic reprogramming inhibits necroptosis through the hypermethylation of the RIP3 promoter

Shi, F., Zhou, M., Shang, L., Du, Q., Li, Y., Xie, L., Liu, X., Tang, M., Luo, X., Fan, J., Zhou, J., Gao, Q., Qiu, S. J., Wu, W., Zhang, X., Bode, A. M. & Cao, Y., Jan 1 2019, In : Theranostics. 9, 9, p. 2424-2438 15 p.

Research output: Contribution to journalArticle

Open Access
Human Herpesvirus 4
Fumarates
Epstein-Barr Virus Infections
Epigenomics
Methylation
1 Citation (Scopus)

Ethyl gallate as a novel ERK1/2 inhibitor suppresses patient-derived esophageal tumor growth

Liu, F., Zu, X., Xie, X., Liu, K., Chen, H., Wang, T., Liu, F., Bode, A. M., Zheng, Y., Dong, Z. & Kim, D. J., Apr 1 2019, In : Molecular Carcinogenesis. 58, 4, p. 533-543 11 p.

Research output: Contribution to journalArticle

Esophageal Neoplasms
Growth
Neoplasms
Cyclin A2
Euphorbia

Fluvastatin inhibits HMG-CoA reductase and prevents non-small cell lung carcinogenesi

Zhang, T., Bai, R., Wang, Q., Wang, K., Li, X., Liu, K., Ryu, J., Wang, T., Chang, X., Ma, W., Bode, A. M., Xia, Q., Song, Y. & Dong, Z., Jan 1 2019, In : Cancer Prevention Research. 12, 12, p. 837-848 12 p.

Research output: Contribution to journalArticle

fluvastatin
Coenzyme A
Hydroxymethylglutaryl CoA Reductases
Non-Small Cell Lung Carcinoma
Oxidoreductases

Gossypetin is a novel MKK3 and MKK6 inhibitor that suppresses esophageal cancer growth in vitro and in vivo

Xie, X., Liu, K., Liu, F., Chen, H., Wang, X., Zu, X., Ma, X., Wang, T., Wu, Q., Zheng, Y., Bode, A. M., Dong, Z. & Kim, D. J., Feb 1 2019, In : Cancer Letters. 442, p. 126-136 11 p.

Research output: Contribution to journalArticle

Esophageal Neoplasms
Growth
MAP Kinase Kinase 3
gossypetin
In Vitro Techniques
2 Citations (Scopus)

Gossypin inhibits gastric cancer growth by direct targeting of AURKA and RSK2

Wang, L., Wang, X., Chen, H., Zu, X., Ma, F., Liu, K., Bode, A. M., Dong, Z. & Kim, D. J., Mar 2019, In : Phytotherapy Research. 33, 3, p. 640-650 11 p.

Research output: Contribution to journalArticle

Aurora Kinase A
Stomach Neoplasms
Growth
flavone
Cyclin A2
2 Citations (Scopus)

Inhibition of LTA4H by bestatin in human and mouse colorectal cancer

Zhao, S., Yao, K., Li, D., Liu, K., Jin, G., Yan, M., Wu, Q., Chen, H., Shin, S. H., Bai, R., Wang, G., Bode, A. M., Dong, Z., Guo, Z. & Dong, Z., Jun 2019, In : EBioMedicine. 44, p. 361-374 14 p.

Research output: Contribution to journalArticle

Open Access
Colorectal Neoplasms
Leukotriene B4
Biomarkers
Leukotriene B4 Receptors
leukotriene A4 hydrolase

Knockdown of Pyruvate Kinase M Inhibits Cell Growth and Migration by Reducing NF-kB Activity in Triple-Negative Breast Cancer Cells

Ma, C., Zu, X., Liu, K., Bode, A. M., Dong, Z., Liu, Z. & Kim, D. J., Sep 30 2019, In : Molecules and cells. 42, 9, p. 628-636 9 p.

Research output: Contribution to journalArticle

Triple Negative Breast Neoplasms
Pyruvate Kinase
NF-kappa B
Cell Movement
Muscles

Lapachol is a novel ribosomal protein S6 kinase 2 inhibitor that suppresses growth and induces intrinsic apoptosis in esophageal squamous cell carcinoma cells

Zu, X., Xie, X., Zhang, Y., Liu, K., Bode, A. M., Dong, Z. & Kim, D. J., Sep 1 2019, In : Phytotherapy Research. 33, 9, p. 2337-2346 10 p.

Research output: Contribution to journalArticle

lapachol
Growth Inhibitors
Apoptosis
Bignoniaceae
Growth
1 Citation (Scopus)

PGC1α/CEBPB/CPT1A axis promotes radiation resistance of nasopharyngeal carcinoma through activating fatty acid oxidation

Du, Q., Tan, Z., Shi, F., Tang, M., Xie, L., Zhao, L., Li, Y., Hu, J., Zhou, M., Bode, A., Luo, X. & Cao, Y., Jun 2019, In : Cancer Science. 110, 6, p. 2050-2062 13 p.

Research output: Contribution to journalArticle

Open Access
Carnitine
Transferases
Fatty Acids
Radiation
Radiotherapy

Protein lysine 43 methylation by EZH1 promotes AML1-ETO transcriptional repression in leukemia

Dou, L., Yan, F., Pang, J., Zheng, D., Li, D., Gao, L., Wang, L., Xu, Y., Shi, J., Wang, Q., Zhou, L., Shen, N., Singh, P., Wang, L., Li, Y., Gao, Y., Liu, T., Chen, C., Al-Kali, A., Litzow, M. R. & 8 others, Chi, Y. I., Bode, A. M., Liu, C., Huang, H., Liu, D., Marcucci, G., Liu, S. & Yu, L., Dec 1 2019, In : Nature communications. 10, 1, 5051.

Research output: Contribution to journalArticle

Open Access
methylation
Methylation
leukemias
lysine
Lysine

Purpurogallin is a novel mitogen-activated protein kinase kinase 1/2 inhibitor that suppresses esophageal squamous cell carcinoma growth in vitro and in vivo

Xie, X., Zu, X., Liu, F., Wang, T., Wang, X., Chen, H., Liu, K., Wang, P., Liu, F., Zheng, Y., Bode, A. M., Dong, Z. & Kim, D. J., Jan 1 2019, In : Molecular Carcinogenesis. 58, 7, p. 1248-1259 12 p.

Research output: Contribution to journalArticle

MAP Kinase Kinase 2
MAP Kinase Kinase 1
Growth
Cyclin A2
G2 Phase Cell Cycle Checkpoints
1 Citation (Scopus)

Scutellarin suppresses patient-derived xenograft tumor growth by directly targeting AKT in esophageal squamous cell carcinoma

Liu, F., Zu, X., Xie, X., Zhang, Y., Liu, K., Chen, H., Wang, I., Bode, A. M., Dong, Z. & Kim, D. J., Jan 1 2019, In : Cancer Prevention Research. 12, 12, p. 849-860 12 p.

Research output: Contribution to journalArticle

Heterografts
Growth
Neoplasms
Proteins
Scutellaria

Targeted therapy of the AKT kinase inhibits esophageal squamous cell carcinoma growth in vitro and in vivo

Liu, X., Song, M., Wang, P., Zhao, R., Chen, H., Zhang, M., Shi, Y., Liu, K., Liu, F., Yang, R., Li, E., Bode, A. M., Dong, Z. & Lee, M. H., Aug 15 2019, In : International Journal of Cancer. 145, 4, p. 1007-1019 13 p.

Research output: Contribution to journalArticle

Open Access
Phosphotransferases
Growth
Heterografts
Therapeutics
Tumor Burden

Targeting the COX1/2-Driven thromboxane A2 pathway suppresses Barrett's esophagus and esophageal adenocarcinoma development

Zhang, T., Wang, Q., Ma, W. Y., Wang, K., Chang, X., Johnson, M. L., Bai, R., Bode, A. M., Foster, N. R., Falk, G. W., Limburg, P. J., Iyer, P. G. & Dong, Z., Nov 2019, In : EBioMedicine. 49, p. 145-156 12 p.

Research output: Contribution to journalArticle

Open Access
Thromboxane A2
Barrett Esophagus
Biopsy
Aspirin
Adenocarcinoma
2018
10 Citations (Scopus)

A vicious loop of fatty acid-binding protein 4 and DNA methyltransferase 1 promotes acute myeloid leukemia and acts as a therapeutic target

Yan, F., Shen, N., Pang, J. X., Zhao, N., Zhang, Y. W., Bode, A. M., Al-Kali, A., Litzow, M. R., Li, B. & Liu, S., Apr 1 2018, In : Leukemia. 32, 4, p. 865-873 9 p.

Research output: Contribution to journalArticle

Fatty Acid-Binding Proteins
Methyltransferases
Acute Myeloid Leukemia
DNA
DNA Methylation
3 Citations (Scopus)

Carnosol suppresses patient-derived gastric tumor growth by targeting RSK2

Wang, L., Zhang, Y., Liu, K., Chen, H., Yang, R., Ma, X., Kim, H. G., Bode, A. M., Kim, D. J. & Dong, Z., Sep 1 2018, In : Oncotarget. 9, 76, p. 34200-34212 13 p.

Research output: Contribution to journalArticle

Stomach
Growth
Stomach Neoplasms
Neoplasms
Origanum
1 Citation (Scopus)

Daily or weekly dosing with EGFR inhibitors, gefitinib and lapatinib, and AKt inhibitor MK2206 in mammary cancer models

Lubet, R. A., Steele, V. E., Juliana, M. M., Bode, A., Moeinpour, F. & Grubbs, C. J., Sep 2018, In : Oncology Reports. 40, 3, p. 1545-1553 9 p.

Research output: Contribution to journalArticle

Open Access
Methylnitrosourea
Breast Neoplasms
Neoplasms
Tumor Burden
vorozole
14 Citations (Scopus)

DNMT1 mediates metabolic reprogramming induced by Epstein-Barr virus latent membrane protein 1 and reversed by grifolin in nasopharyngeal carcinoma

Luo, X., Hong, L., Cheng, C., Li, N., Zhao, X., Shi, F., Liu, J., Fan, J., Zhou, J., Bode, A. M. & Cao, Y., Jun 1 2018, In : Cell Death and Disease. 9, 6, 619.

Research output: Contribution to journalArticle

Open Access
Epigenomics
CpG Islands
Oxidative Phosphorylation
Neoplasms
Human Herpesvirus 4
13 Citations (Scopus)

Epstein-Barr virus encoded latent membrane protein 1 suppresses necroptosis through targeting RIPK1/3 ubiquitination article

Liu, X., Li, Y., Peng, S., Yu, X., Li, W., Shi, F., Luo, X., Tang, M., Tan, Z., Bode, A. M. & Cao, Y., Feb 1 2018, In : Cell Death and Disease. 9, 2, 53.

Research output: Contribution to journalArticle

Open Access
Ubiquitination
Protein Kinases
Membrane Proteins
Human Herpesvirus 4
Cell Death
3 Citations (Scopus)

IDH2 is a novel diagnostic and prognostic serum biomarker for non-small-cell lung cancer

Li, J. J., Li, R., Wang, W., Zhang, B., Song, X., Zhang, C., Gao, Y., Liao, Q., He, Y., You, S., Tan, Z., Luo, X., Li, Y., Tang, M., Weng, X., Yi, W., Peng, S., Liu, S., Tan, Y., Bode, A. M. & 1 others, Cao, Y., May 2018, In : Molecular Oncology. 12, 5, p. 602-610 9 p.

Research output: Contribution to journalArticle

Open Access
Non-Small Cell Lung Carcinoma
Biomarkers
Serum
Lung Neoplasms
Proteins
6 Citations (Scopus)

Losmapimod Overcomes Gefitinib Resistance in Non-small Cell Lung Cancer by Preventing Tetraploidization

Yeung, Y. T., Yin, S., Lu, B., Fan, S., Yang, R., Bai, R., Zhang, C., Bode, A. M., Liu, K. & Dong, Z., Feb 2018, In : EBioMedicine. 28, p. 51-61 11 p.

Research output: Contribution to journalArticle

Non-Small Cell Lung Carcinoma
Cells
Epidermal Growth Factor Receptor
p38 Mitogen-Activated Protein Kinases
Tetraploidy
6 Citations (Scopus)

Pharmacological TLR4 antagonism using topical resatorvid blocks solar UV-induced skin tumorigenesis in SKH-1 mice

Blohm-Mangone, K., Burkett, N. B., Tahsin, S., Myrdal, P. B., Aodah, A., Ho, B., Janda, J., McComas, M., Saboda, K., Roe, D. J., Dong, Z., Bode, A. M., Petricoin, E. F., Calvert, V. S., Curiel-Lewandrowski, C., Alberts, D. S., Wondrak, G. T. & Dickinson, S. E., May 2018, In : Cancer Prevention Research. 11, 5, p. 265-277 13 p.

Research output: Contribution to journalArticle

Toll-Like Receptor 4
Carcinogenesis
Pharmacology
Skin
Skin Neoplasms
3 Citations (Scopus)

RSK2 is required for TRAF6 phosphorylation-mediated colon inflammation

Yao, K., Lee, S. Y., Peng, C., Lim, D. Y., Yamamoto, H., Ryu, J., Lim, T. G., Chen, H., Jin, G., Zhao, Z., Han, Y., Ma, W. Y., Bode, A. M. & Dong, Z., Jun 1 2018, In : Oncogene. 37, 26, p. 3501-3513 13 p.

Research output: Contribution to journalArticle

TNF Receptor-Associated Factor 6
Colon
Phosphorylation
Inflammation
Ubiquitination
8 Citations (Scopus)

Targeting AKT with oridonin inhibits growth of esophageal squamous cell carcinoma in vitro and patient-derived xenografts in vivo

Song, M., Liu, X., Liu, K., Zhao, R., Huang, H., Shi, Y., Zhang, M., Zhou, S., Xie, H., Chen, H., Li, Y., Zheng, Y., Wu, Q., Liu, F., Li, E., Bode, A. M., Dong, Z. & Lee, M. H., Jul 2018, In : Molecular Cancer Therapeutics. 17, 7, p. 1540-1553 14 p.

Research output: Contribution to journalArticle

Heterografts
Growth
Isodon
Caspase 7
Neoplasms
18 Citations (Scopus)

Targeting CPT1A-mediated fatty acid oxidation sensitizes nasopharyngeal carcinoma to radiation therapy

Tan, Z., Xiao, L., Tang, M., Bai, F., Li, J., Li, L., Shi, F., Li, N., Li, Y., Du, Q., Lu, J., Weng, X., Yi, W., Zhang, H., Fan, J., Zhou, J., Gao, Q., Onuchic, J. N., Bode, A. M., Luo, X. & 1 others, Cao, Y., Jan 1 2018, In : Theranostics. 8, 9, p. 2329-2347 19 p.

Research output: Contribution to journalArticle

Open Access
Carnitine
Transferases
Radiotherapy
Fatty Acids
Radiation
3 Citations (Scopus)

Targeting PRPK and TOPK for skin cancer prevention and therapy

Roh, E., Lee, M. H., Zykova, T. A., Zhu, F., Nadas, J., Kim, H. G., Bae, K. B., Li, Y., Cho, Y. Y., Curiel-Lewandrowski, C., Einspahr, J., Dickinson, S. E., Bode, A. M. & Dong, Z., Oct 18 2018, In : Oncogene. 37, 42, p. 5633-5647 15 p.

Research output: Contribution to journalArticle

Lymphokine-Activated Killer Cells
Skin Neoplasms
Protein Kinases
Skin
Hairless Mouse
2 Citations (Scopus)

Targeting prpk function blocks colon cancer metastasis

Zykova, T., Zhu, F., Wang, L., Li, H., Lim, D. Y., Yao, K., Roh, E., Yoon, S. P., Kim, H. G., Bae, K. B., Wen, W., Shin, S. H., Nadas, J., Li, Y., Ma, W., Bode, A. M. & Dong, Z., May 2018, In : Molecular Cancer Therapeutics. 17, 5, p. 1101-1113 13 p.

Research output: Contribution to journalArticle

Colonic Neoplasms
Protein Kinases
Neoplasm Metastasis
Fusidic Acid
Fluorouracil

The Ashitaba (Angelica keiskei) Chalcones 4-hydroxyderricin and xanthoangelol suppress melanomagenesis by targeting BRAF and PI3K

Zhang, T., Wang, Q., Fredimoses, M., Gao, G., Wang, K., Chen, H., Wang, T., Oi, N., Zykova, T. A., Reddy, K., Yao, K., Ma, W., Chang, X., Lee, M. H., Rathore, M. G., Bode, A. M., Ashida, H., Lippman, S. M. & Dong, Z., Oct 2018, In : Cancer Prevention Research. 11, 10, p. 607-619 13 p.

Research output: Contribution to journalArticle

Angelica
Chalcones
Phosphatidylinositol 3-Kinases
Melanoma
Apoptosis
4 Citations (Scopus)

TRAF1 is critical for regulating the BRAF/MEK/ERK pathway in non–small cell lung carcinogenesis

Wang, Q., Gao, G., Zhang, T., Yao, K., Chen, H., Park, M. H., Yamamoto, H., Wang, K., Ma, W., Malakhova, M., Bode, A. M. & Dong, Z., Jul 15 2018, In : Cancer Research. 78, 14, p. 3982-3994 13 p.

Research output: Contribution to journalArticle

MAP Kinase Signaling System
Tumor Necrosis Factor Receptor-Associated Peptides and Proteins
Non-Small Cell Lung Carcinoma
Lung Neoplasms
Carcinogenesis
6 Citations (Scopus)

Veratramine modulates AP-1-dependent gene transcription by directly binding to programmable DNA

Bai, F., Liu, K., Li, H., Wang, J., Zhu, J., Hao, P., Zhu, L., Zhang, S., Shan, L., Ma, W-Y., Bode, A. M., Zhang, W., Li, H. & Dong, Z., Jan 25 2018, In : Nucleic acids research. 46, 2, p. 546-557 12 p.

Research output: Contribution to journalArticle

Open Access
Transcription Factor AP-1
DNA
Genes
Transcription Factors
veratramine
8 Citations (Scopus)

Wild-type IDH2 promotes the Warburg effect and tumor growth through HIF1α in lung cancer

Li, J., He, Y., Tan, Z., Lu, J., Li, L., Song, X., Shi, F., Xie, L., You, S., Luo, X., Li, N., Li, Y., Liu, X., Tang, M., Weng, X., Yi, W., Fan, J., Zhou, J., Qiang, G., Qiu, S. J. & 3 others, Wu, W., Bode, A. M. & Cao, Y., Jan 1 2018, In : Theranostics. 8, 15, p. 4050-4061 12 p.

Research output: Contribution to journalArticle

Open Access
Lung Neoplasms
Growth
Neoplasms
Cell Proliferation
Isocitrate Dehydrogenase
2017
11 Citations (Scopus)

ADA-07 suppresses solar ultraviolet–induced skin carcinogenesis by directly inhibiting TOPK

Gao, G., Zhang, T., Wang, Q., Reddy, K., Chen, H., Yao, K., Wang, K., Roh, E., Zykova, T., Ma, W., Ryu, J., Curiel-Lewandrowski, C., Alberts, D., Dickinson, S. E., Bode, A. M., Xing, Y. & Dong, Z., Sep 2017, In : Molecular Cancer Therapeutics. 16, 9, p. 1843-1854 12 p.

Research output: Contribution to journalArticle

Protein Kinases
Carcinogenesis
Skin Neoplasms
Protein Kinase Inhibitors
Skin
5 Citations (Scopus)

A new functional IDH2 genetic variant is associated with the risk of lung cancer

Li, J., Lu, J., He, Y., Wu, Y., Wu, Y., Song, X., Jiang, Y., Tang, M., Weng, X., Yi, W., Luo, X., Sun, L., Bode, A. M. & Cao, Y., Mar 1 2017, In : Molecular Carcinogenesis. 56, 3, p. 1082-1087 6 p.

Research output: Contribution to journalArticle

Lung Neoplasms
Isocitrate Dehydrogenase
Cell Survival
Healthy Volunteers
Alleles
14 Citations (Scopus)

A Small Molecule Inhibitor of the β-Catenin-TCF4 Interaction Suppresses Colorectal Cancer Growth In Vitro and In Vivo

Shin, S. H., Lim, D. Y., Reddy, K., Malakhova, M., Liu, F., Wang, T., Song, M., Chen, H., Bae, K. B., Ryu, J., Liu, K., Lee, M. H., Bode, A. M. & Dong, Z., Nov 2017, In : EBioMedicine. 25, p. 22-31 10 p.

Research output: Contribution to journalArticle

Transcription Factor 7-Like 2 Protein
Catenins
Colorectal Neoplasms
Molecules
Growth
26 Citations (Scopus)

Fatty acid-binding protein FABP4 mechanistically links obesity with aggressive AML by enhancing aberrant DNA methylation in AML cells

Yan, F., Shen, N., Pang, J. X., Zhang, Y. W., Rao, E. Y., Bode, A. M., Al-Kali, A., Zhang, D. E., Litzow, M. R., Li, B. & Liu, S., Jun 1 2017, In : Leukemia. 31, 6, p. 1434-1442 9 p.

Research output: Contribution to journalArticle

Fatty Acid-Binding Proteins
Myeloid Cells
DNA Methylation
Acute Myeloid Leukemia
Obesity
8 Citations (Scopus)

Herbacetin suppresses cutaneous squamous cell carcinoma and melanoma cell growth by targeting AKT and ODC

Kim, D. J., Lee, M. H., Liu, K. D., Lim, D. Y., Roh, E., Chen, H., Kim, S. H., Shim, J. H., Kim, M. O., Li, W., Ma, F., Fredimoses, M., Bode, A. M. & Dong, Z., Nov 1 2017, In : Carcinogenesis. 38, 11, p. 1136-1146 11 p., bgx082.

Research output: Contribution to journalArticle

Ornithine Decarboxylase
Squamous Cell Carcinoma
Melanoma
Skin
Skin Neoplasms
12 Citations (Scopus)

Inactivation of receptor tyrosine kinases reverts aberrant DNA methylation in acute myeloid leukemia

Shen, N., Yan, F., Pang, J., Zhao, N., Gangat, N., Wu, L., Bode, A. M., Al-Kali, A., Litzow, M. R. & Liu, S., Oct 15 2017, In : Clinical Cancer Research. 23, 20, p. 6254-6267 14 p.

Research output: Contribution to journalArticle

Receptor Protein-Tyrosine Kinases
DNA Methylation
Acute Myeloid Leukemia
Methyltransferases
Leukemia
2 Citations (Scopus)

Lack of chemopreventive efficacy of metformin in rodent models of urinary bladder, head and neck, and colon/intestine cancer

Thompson, M. D., Lubet, R. A., McCormick, D. L., Clapper, M. L., Bode, A. M., Juliana, M. M., Moeinpour, F. & Grubbs, C. J., Jan 1 2017, In : Oncology Letters. 14, 3, p. 3480-3486 7 p.

Research output: Contribution to journalArticle

Open Access
Intestinal Neoplasms
Metformin
Colonic Neoplasms
Rodentia
Urinary Bladder
5 Citations (Scopus)

LTA4H regulates cell cycle and skin carcinogenesis

Oi, N., Yamamoto, H., Langfald, A., Bai, R., Lee, M. H., Bode, A. M. & Dong, Z., Jul 1 2017, In : Carcinogenesis. 38, 7, p. 728-737 10 p., bgx049.

Research output: Contribution to journalArticle

Cell Cycle
Carcinogenesis
Skin Neoplasms
Skin
Cell Cycle Resting Phase
29 Citations (Scopus)

Molecular mechanisms of green tea polyphenols with protective effects against skin photoaging

Roh, E., Kim, J. E., Kwon, J. Y., Park, J. S., Bode, A. M., Dong, Z. & Lee, K. W., May 24 2017, In : Critical Reviews in Food Science and Nutrition. 57, 8, p. 1631-1637 7 p.

Research output: Contribution to journalArticle

photoaging
Skin Aging
Skin effect
Polyphenols
green tea
20 Citations (Scopus)

Neoalbaconol inhibits angiogenesis and tumor growth by suppressing EGFR-mediated VEGF production

Yu, X., Li, W., Deng, Q., You, S., Liu, H., Peng, S., Liu, X., Lu, J., Luo, X., Yang, L., Tang, M., Weng, X., Yi, W., Liu, W., Wu, S., Ding, Z., Feng, T., Zhou, J., Fan, J., Bode, A. M. & 3 others, Dong, Z., Liu, J. & Cao, Y., May 2017, In : Molecular Carcinogenesis. 56, 5, p. 1414-1426 13 p.

Research output: Contribution to journalArticle

Vascular Endothelial Growth Factor A
Growth
Neoplasms
Endothelial Cells
neoalbaconol
9 Citations (Scopus)

Phosphorylation of NFAT3 by CDK3 induces cell transformation and promotes tumor growth in skin cancer

Xiao, T., Zhu, J. J., Huang, S., Peng, C., He, S., Du, J., Hong, R., Chen, X., Bode, A. M., Jiang, W., Dong, Z. & Zheng, D., May 18 2017, In : Oncogene. 36, 20, p. 2835-2845 11 p.

Research output: Contribution to journalArticle

Cyclin-Dependent Kinase 3
Skin Neoplasms
Serine
NFATC Transcription Factors
Phosphorylation
1 Citation (Scopus)

RSK2 phosphorylates T-bet to attenuate colon cancer metastasis and growth

Yao, K., Peng, C., Zhang, Y., Zykova, T. A., Lee, M. H., Lee, S. Y., Rao, E., Chen, H., Ryu, J., Wang, L., Zhang, Y., Gao, G., He, W., Ma, W. Y., Liu, K., Bode, A. M., Dong, Z., Li, B. & Dong, Z., Nov 28 2017, In : Proceedings of the National Academy of Sciences of the United States of America. 114, 48, p. 12791-12796 6 p.

Research output: Contribution to journalArticle

Colonic Neoplasms
Neoplasm Metastasis
Growth
Knockout Mice
Phosphorylation
1 Citation (Scopus)

Serine 347 Phosphorylation by JNKs Negatively Regulates OCT4 Protein Stability in Mouse Embryonic Stem Cells

Bae, K. B., Yu, D. H., Lee, K. Y., Yao, K., Ryu, J., Lim, D. Y., Zykova, T. A., Kim, M. O., Bode, A. M. & Dong, Z., Dec 12 2017, In : Stem Cell Reports. 9, 6, p. 2050-2064 15 p.

Research output: Contribution to journalArticle

Phosphorylation
JNK Mitogen-Activated Protein Kinases
Protein Stability
Stem cells
Induced Pluripotent Stem Cells
2 Citations (Scopus)

Small molecule inhibitors of mesotrypsin from a structurebased docking screen

Kayode, O., Huang, Z., Soares, A. S., Caulfield, T. R., Dong, Z., Bode, A. M. & Radisky, E. S., May 2017, In : PloS one. 12, 5, e0176694.

Research output: Contribution to journalArticle

Diminazene
diminazene
crystal structure
Crystal structure
Trypsin