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Research Output 1982 2019

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Article
2019
4 Citations (Scopus)

CRISPR/Cas9 methodology for the generation of knockout deletions in caenorhabditis elegans

Au, V., Li-Leger, E., Raymant, G., Flibotte, S., Chen, G., Martin, K., Fernando, L., Doell, C., Rosell, F. I., Wang, S., Edgley, M. L., Rougvie, A. E., Hutter, H. & Moerman, D. G., Jan 1 2019, In : G3: Genes, Genomes, Genetics. 9, 1, p. 135-144 10 p.

Research output: Contribution to journalArticle

Clustered Regularly Interspaced Short Palindromic Repeats
Caenorhabditis elegans
Open Reading Frames
Guide RNA
Gene Knockout Techniques
3 Citations (Scopus)

Recompleting the Caenorhabditis elegans genome

Yoshimura, J., Ichikawa, K., Shoura, M. J., Artiles, K. L., Gabdank, I., Wahba, L., Smith, C. L., Edgley, M. L., Rougvie, A. E., Fire, A. Z., Morishita, S. & Schwarz, E. M., Jan 1 2019, In : Genome research. 29, 6, p. 1009-1022 14 p.

Research output: Contribution to journalArticle

Open Access
Caenorhabditis elegans
Genome
Tandem Repeat Sequences
Systems Biology
Genomics
2016
4 Citations (Scopus)

Analysis of a lin-42/period null allele implicates all three isoforms in regulation of caenorhabditis elegans molting and developmental timing

Edelman, T. L. B., McCulloch, K. A., Barr, A., Frøkjær-Jensen, C., Jorgensen, E. M. & Rougvie, A. E., Jan 1 2016, In : G3: Genes, Genomes, Genetics. 6, 12, p. 4077-4086 10 p.

Research output: Contribution to journalArticle

Molting
Caenorhabditis elegans
Protein Isoforms
Alleles
Phenotype
2015
13 Citations (Scopus)

The C. Elegans hypodermis couples progenitor cell quiescence to the dietary state

Fukuyama, M., Kontani, K., Katada, T. & Rougvie, A. E., May 4 2015, In : Current Biology. 25, 9, p. 1241-1248 8 p.

Research output: Contribution to journalArticle

Subcutaneous Tissue
stem cells
Stem Cells
Amino Acids
Ethanol
2014
9 Citations (Scopus)
Caenorhabditis elegans
MicroRNAs
Gene Components
3' Untranslated Regions
Cell Lineage
2012
42 Citations (Scopus)

C. Elegans AMPKs promote survival and arrest germline development during nutrient stress

Fukuyama, M., Sakuma, K., Park, R., Kasuga, H., Nagaya, R., Atsumi, Y., Shimomura, Y., Takahashi, S., Kajiho, H., Rougvie, A. E., Kontani, K. & Katada, T., Oct 15 2012, In : Biology Open. 1, 10, p. 929-936 8 p.

Research output: Contribution to journalArticle

AMP-activated protein kinase
AMP-Activated Protein Kinases
Stem cells
diapause
Nutrients
2010
18 Citations (Scopus)

The C. elegans developmental timing protein LIN-42 regulates diapause in response to environmental cues

Tennessen, J. M., Opperman, K. J. & Rougvie, A. E., Oct 15 2010, In : Development. 137, 20, p. 3501-3511 11 p.

Research output: Contribution to journalArticle

environmental cue
diapause
ligand
Cues
Larva
2006
96 Citations (Scopus)

C. elegans DAF-18/PTEN Mediates Nutrient-Dependent Arrest of Cell Cycle and Growth in the Germline

Fukuyama, M., Rougvie, A. E. & Rothman, J. H., Apr 18 2006, In : Current Biology. 16, 8, p. 773-779 7 p.

Research output: Contribution to journalArticle

Signal transduction
Caenorhabditis elegans
Chromosomes
Cell Cycle Checkpoints
diapause
45 Citations (Scopus)

Novel heterochronic functions of the Caenorhabditis elegans period-related protein LIN-42

Tennessen, J. M., Gardner, H. F., Volk, M. L. & Rougvie, A. E., Jan 1 2006, In : Developmental Biology. 289, 1, p. 30-43 14 p.

Research output: Contribution to journalArticle

Caenorhabditis elegans Proteins
Period Circadian Proteins
Gonads
Vulva
Myoblasts
2005
78 Citations (Scopus)

Regulatory mutations of mir-48, a C. elegans let-7 family microRNA, cause developmental timing defects

Li, M., Jones-Rhoades, M. W., Lau, N. C., Bartel, D. P. & Rougvie, A. E., Sep 1 2005, In : Developmental Cell. 9, 3, p. 415-422 8 p.

Research output: Contribution to journalArticle

MicroRNAs
Genes
Alleles
Point Mutation
Defects
2003
128 Citations (Scopus)

Chromosome cohesion is regulated by a clock gene paralogue TIM-1

Chan, R. C., Chan, A., Jeon, M., Wu, T. F., Pasqualone, D., Rougvie, A. E. & Meyer, B. J., Jun 26 2003, In : Nature. 423, 6943, p. 1002-1009 8 p.

Research output: Contribution to journalArticle

Chromosomes
Genes
Chromosome Pairing
Caenorhabditis elegans
Circadian Clocks
270 Citations (Scopus)

The Caenorhabditis elegans hunchback-like gene lin-57/hbl-1 controls developmental time and is regulated by microRNAs

Abrahante, J. E., Daul, A. L., Li, M., Volk, M. L., Tennessen, J. M., Miller, E. A. & Rougvie, A. E., May 1 2003, In : Developmental Cell. 4, 5, p. 625-637 13 p.

Research output: Contribution to journalArticle

Caenorhabditis elegans
Neurology
MicroRNAs
Nervous System
Genes
2001
91 Citations (Scopus)

Control of developmental timing in animals

Rougvie, A. E., Sep 1 2001, In : Nature Reviews Genetics. 2, 9, p. 690-701 12 p.

Research output: Contribution to journalArticle

Caenorhabditis elegans
RNA
Double-Stranded RNA
double-stranded RNA
RNA Interference
1999
125 Citations (Scopus)

Similarity of the C. elegans developmental timing protein LIN-42 to circadian rhythm proteins

Jeon, M., Gardner, H. F., Miller, E. A., Deshler, J. & Rougvie, A. E., Nov 5 1999, In : Science. 286, 5442, p. 1141-1146 6 p.

Research output: Contribution to journalArticle

Circadian Rhythm
Molting
Messenger RNA
Subcutaneous Tissue
Caenorhabditis elegans
18 Citations (Scopus)

The LIN-29 transcription factor is required for proper morphogenesis of the Caenorhabditis elegans male tail

Euling, S., Bettinger, J. C. & Rougvie, A. E., Feb 15 1999, In : Developmental Biology. 206, 2, p. 142-156 15 p.

Research output: Contribution to journalArticle

Caenorhabditis elegans
Morphogenesis
Tail
Transcription Factors
Vulva
1998
51 Citations (Scopus)
Gene Fusion
Caenorhabditis elegans
Green Fluorescent Proteins
Collagen
Genes
1997
28 Citations (Scopus)

The terminal differentiation factor LIN-29 is required for proper vulval morphogenesis and egg laying in Caenorhabditis elegans

Bettinger, J. C., Euling, S. & Rougvie, A. E., Dec 2 1997, In : Development. 124, 21, p. 4333-4342 10 p.

Research output: Contribution to journalArticle

Vulva
morphogenesis
Caenorhabditis elegans
Morphogenesis
Ovum
1996
89 Citations (Scopus)

Stage-specific accumulation of the terminal differentiation factor LIN-29 during Caenorhabditis elegans development

Bettinger, J. C., Lee, K. & Rougvie, A. E., Aug 23 1996, In : Development. 122, 8, p. 2517-2527 11 p.

Research output: Contribution to journalArticle

Subcutaneous Tissue
Caenorhabditis elegans
loss of function
molt
Cell Nucleus
1995
100 Citations (Scopus)

The heterochronic gene lin-29 encodes a zinc finger protein that controls a terminal differentiation event in Caenorhabditis elegans

Rougvie, A. E. & Ambros, V., Jan 1 1995, In : Development. 121, 8, p. 2491-2500 10 p.

Research output: Contribution to journalArticle

Zinc Fingers
Caenorhabditis elegans
zinc
Subcutaneous Tissue
protein
1991
21 Citations (Scopus)

Chapter 14 Protein—DNA Cross-Linking as a Means to Determine the Distribution of Proteins on DNA in Vivo

Gilmour, D. S., Rougvie, A. E. & Lis, J. T., Jan 1 1991, In : Methods in cell biology. 35, C, p. 369-381 13 p.

Research output: Contribution to journalArticle

DNA
Proteins
Drosophila
Type I DNA Topoisomerase
RNA Polymerase II
13 Citations (Scopus)
Yeast Artificial Chromosomes
Molting
Molecular Cloning
Cell Differentiation
Cosmids
1990
130 Citations (Scopus)

Postinitiation transcriptional control in Drosophila melanogaster

Rougvie, A. E. & Lis, J. T., Jan 1 1990, In : Molecular and Cellular Biology. 10, 11, p. 6041-6045 5 p.

Research output: Contribution to journalArticle

Drosophila melanogaster
Drosophila
Genes
RNA Polymerase II
Shock
1988
421 Citations (Scopus)

The RNA polymerase II molecule at the 5′ end of the uninduced hsp70 gene of D. melanogaster is transcriptionally engaged

Rougvie, A. E. & Lis, J. T., Sep 9 1988, In : Cell. 54, 6, p. 795-804 10 p.

Research output: Contribution to journalArticle

RNA Polymerase II
Hot Temperature
Genes
Genetic Promoter Regions
Molecules
1982
10 Citations (Scopus)

Glutamate dehydrogenase catalyzes the reduction of a Schiff base (delta 1-pyrroline-2-carboxylic acid) by NADPH.

Fisher, H. F., Srinivasan, R. & Rougvie, A. E., Nov 25 1982, In : Journal of Biological Chemistry. 257, 22, p. 13208-13210 3 p.

Research output: Contribution to journalArticle

Glutamate Dehydrogenase
Schiff Bases
Carboxylic Acids
NADP
Enzymes