20092017
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Fingerprint The Fingerprint is created by mining the titles and abstracts of the person's research outputs and projects/funding awards to create an index of weighted terms from discipline-specific thesauri.

  • 4 Similar Profiles
TNF-Related Apoptosis-Inducing Ligand Receptors Medicine & Life Sciences
Tumor Necrosis Factor Receptors Medicine & Life Sciences
Ligands Medicine & Life Sciences
Hydrogels Chemical Compounds
Tissue engineering Chemical Compounds
Methionine Medicine & Life Sciences
Dimers Chemical Compounds
Tumor Necrosis Factor-alpha Medicine & Life Sciences

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Research Output 2009 2017

6 Citations (Scopus)

An Innovative High-Throughput Screening Approach for Discovery of Small Molecules That Inhibit TNF Receptors

Lo, C. H., Vunnam, N., Lewis, A. K., Chiu, T. L., Brummel, B. E., Schaaf, T. M., Grant, B. D., Bawaskar, P., Thomas, D. D. & Sachs, J. N., Sep 1 2017, In : SLAS Discovery. 22, 8, p. 950-961 12 p.

Research output: Contribution to journalArticle

Open Access
Tumor Necrosis Factor Receptors
Screening
triclabendazole
Throughput
Ligands
1 Citation (Scopus)

Death Receptor 5 Activation Is Energetically Coupled to Opening of the Transmembrane Domain Dimer

Vunnam, N., Campbell-Bezat, C. K., Lewis, A. K. & Sachs, J. N., Jul 25 2017, In : Biophysical journal. 113, 2, p. 381-392 12 p.

Research output: Contribution to journalArticle

TNF-Related Apoptosis-Inducing Ligand Receptors
Fluorescence Resonance Energy Transfer
Ligands
Tumor Necrosis Factor Receptors
Lipid Bilayers
2 Citations (Scopus)

Minimal Nucleation State of α-Synuclein Is Stabilized by Dynamic Threonine-Water Networks

Romo, T. D., Lewis, A. K., Braun, A. R., Grossfield, A. & Sachs, J. N., Sep 20 2017, In : ACS Chemical Neuroscience. 8, 9, p. 1859-1864 6 p.

Research output: Contribution to journalArticle

Synucleins
Threonine
Nucleation
Water
Facings
6 Citations (Scopus)

Piecing it together: Unraveling the elusive structure-function relationship in single-pass membrane receptors

Valley, C. C., Lewis, A. K. & Sachs, J. N., Sep 1 2017, In : Biochimica et Biophysica Acta - Biomembranes. 1859, 9, p. 1398-1416 19 p.

Research output: Contribution to journalReview article

Chemical activation
Membranes
Tumor Necrosis Factor Receptors
Structural Models
Oligomerization
6 Citations (Scopus)

Death Receptor 5 Networks Require Membrane Cholesterol for Proper Structure and Function

Lewis, A. K., Valley, C. C., Peery, S. L., Brummel, B., Braun, A. R., Karim, C. B. & Sachs, J. N., Dec 4 2016, In : Journal of Molecular Biology. 428, 24, p. 4843-4855 13 p.

Research output: Contribution to journalArticle

TNF-Related Apoptosis-Inducing Ligand Receptors
Cholesterol
Membranes
Dimerization
Tumor Necrosis Factor Receptors