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Research Output 2002 2018

2018

Mitochondria remodeling in cancer

Dornfeld, K. J. & Skildum, A. J., Mar 21 2018, Mitochondrial Biology and Experimental Therapeutics. Springer International Publishing, p. 153-191 39 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Mitochondria
Metabolism
Cells
Neoplasms
Nutrients
2017
4 Citations (Scopus)

A tRNA fragment, tRF5-Glu, regulates BCAR3 expression and proliferation in ovarian cancer cells

Zhou, K., Diebel, K. W., Holy, J. M., Skildum, A. J., Odean, E., Hicks, D. A., Schotl, B., Abrahante - Llorens, J. E., Spillman, M. A. & Bemis, L. T., Jan 1 2017, In : Oncotarget. 8, 56, p. 95377-95391 15 p.

Research output: Contribution to journalArticle

Open Access
RNA, Transfer, Glu
Transfer RNA
Ovarian Neoplasms
Estrogens
Breast Neoplasms

Development of an interdisciplinary pre-matriculation program designed to promote medical students' self efficacy

Wirta Kosobuski, A., Whitney, A., Skildum, A. J. & Prunuske, A. J., Jan 1 2017, In : Medical Education Online. 22, 1, 1272835.

Research output: Contribution to journalArticle

self-efficacy
medical student
student
school
confidence
1 Citation (Scopus)

Development of an interdisciplinary pre-matriculation program designed to promote medical students' self efficacy

Wirta Kosobuski, A., Whitneyb, A., Skildum, A. J. & Prunuske, A. J., Jan 1 2017, In : Medical Education Online. 22, 1, 1272835.

Research output: Contribution to journalArticle

Self Efficacy
Medical Students
self-efficacy
medical student
Students
2015
3 Citations (Scopus)

Altered regulation of PDK4 expression promotes antiestrogen resistance in human breast cancer cells

Walter, W., Thomalla, J., Bruhn, J., Fagan, D. H., Zehowski, C., Yee, D. & Skildum, A. J., Dec 1 2015, In : SpringerPlus. 4, 1, p. 1-13 13 p., 689.

Research output: Contribution to journalArticle

Estrogen Receptor Modulators
MCF-7 Cells
Breast Neoplasms
Pyruvic Acid
Oxidoreductases
4 Citations (Scopus)

Aspartate facilitates mitochondrial function, growth arrest and survival during doxorubicin exposure

Dornfeld, K., Madden, M., Skildum, A. & Wallace, K. B., Jan 1 2015, In : Cell Cycle. 14, 20, p. 3282-3291 10 p.

Research output: Contribution to journalArticle

Aspartic Acid
Doxorubicin
Growth
Saccharomyces cerevisiae
Amino Acids
12 Citations (Scopus)

Stimulating basal mitochondrial respiration decreases doxorubicin apoptotic signaling in H9c2 cardiomyoblasts

Deus, C. M., Zehowski, C., Nordgren, K., Wallace, K. B., Skildum, A. & Oliveira, P. J., Aug 6 2015, In : Toxicology. 334, p. 1-11 11 p.

Research output: Contribution to journalArticle

Doxorubicin
Respiration
troglitazone
Cytotoxicity
Peroxisome Proliferator-Activated Receptors
12 Citations (Scopus)
Cytosine
Metabolites
Methylation
Epigenomics
Histones
2014
3 Citations (Scopus)

Just-in-Time Remediation of Medical Students During the Preclinical Years

Prunuske, A. J. & Skildum, A. J., Mar 1 2014, In : Medical Science Educator. 24, 1, p. 103-109 7 p.

Research output: Contribution to journalArticle

Medical Students
medical student
Students
student
Medical Schools
2012
61 Citations (Scopus)

Mitochondrial remodeling in cancer metabolism and survival: Potential for new therapies

Barbosa, I. A., Machado, N. G., Skildum, A. J., Scott, P. M. & Oliveira, P. J., Aug 1 2012, In : Biochimica et Biophysica Acta - Reviews on Cancer. 1826, 1, p. 238-254 17 p.

Research output: Contribution to journalReview article

Neoplasms
Organelles
Mitochondria
Therapeutics
Carcinogenesis
2011
15 Citations (Scopus)
troglitazone
Estrogen Receptor Modulators
Doxorubicin
Breast Neoplasms
Neoplasms
2009
7 Citations (Scopus)

Short-term prophylactic tamoxifen reduces the incidence of antiestrogen-resistant/estrogen receptor-positive/progesterone receptor-negative mammary tumors

Rose-Hellekant, T., Skildum, A. J., Zhdankin, O., Greene, A. L., Regal, R. R., Kundel, K. D. & Kundel, D. W., May 1 2009, In : Cancer Prevention Research. 2, 5, p. 496-502 7 p.

Research output: Contribution to journalArticle

Estrogen Receptor Modulators
Progesterone Receptors
Tamoxifen
Estrogen Receptors
Breast Neoplasms
2008
18 Citations (Scopus)

Bioactive polybrominated diphenyl ethers from the marine sponge Dysidea sp.

Zhang, H., Skildum, A. J., Stromquist, E., Rose-Hellekant, T. & Leng, C. C., Feb 1 2008, In : Journal of Natural Products. 71, 2, p. 262-264 3 p.

Research output: Contribution to journalArticle

Dysidea
Federated States of Micronesia
Micronesia
Halogenated Diphenyl Ethers
polybrominated diphenyl ethers
2007
20 Citations (Scopus)

Functional ablation of pRb activates Cdk2 and causes antiestrogen resistance in human breast cancer cells

Varma, H., Skildum, A. J. & Conrad, S. E., Dec 5 2007, In : PLoS One. 2, 12, e1256.

Research output: Contribution to journalArticle

Estrogen Receptor Modulators
cyclin-dependent kinase
Ablation
breast neoplasms
Cells
59 Citations (Scopus)
Phosphorylation
Cell growth
Progestins
Progesterone Receptors
Epidermal Growth Factor
2005
69 Citations (Scopus)

Integration of progesterone receptor mediated rapid signaling and nuclear actions in breast cancer cell models: Role of mitogen-activated protein kinases and cell cycle regulators

Faivre, E., Skildum, A. J., Pierson-Mullany, L. & Lange, C. A., Jan 1 2005, In : Steroids. 70, 5-7 SPEC. ISS., p. 418-426 9 p.

Research output: Contribution to journalArticle

Progesterone Receptors
Mitogen-Activated Protein Kinases
Cell Cycle
Cells
Breast Neoplasms
93 Citations (Scopus)

Progesterone receptors induce cell cycle progression via activation of mitogen-activated protein kinases

Skildum, A. J., Faivre, E. & Lange, C. A., Feb 1 2005, In : Molecular Endocrinology. 19, 2, p. 327-339 13 p.

Research output: Contribution to journalArticle

Progesterone Receptors
Mitogen-Activated Protein Kinases
Progestins
Cell Cycle
Mitogen-Activated Protein Kinase 3
2003
9 Citations (Scopus)

Cross-talk between growth factor and progesterone receptor signaling pathways: Implications for breast cancer cell growth

Pierson-Mullany, L. K., Skildum, A. J., Faivre, E. & Lange, C. A., Jan 1 2003, In : Breast Disease. 18, p. 21-31 11 p.

Research output: Contribution to journalReview article

Growth Factor Receptors
Progesterone Receptors
Breast Neoplasms
Progestins
Growth
2002
29 Citations (Scopus)

The cyclin-dependent kinase inhibitor p21WAF1/Cip1 is an antiestrogen-regulated inhibitor of Cdk4 in human breast cancer cells

Skildum, A. J., Mukherjee, S. & Conrad, S. E., Feb 15 2002, In : Journal of Biological Chemistry. 277, 7, p. 5145-5152 8 p.

Research output: Contribution to journalArticle

Estrogen Receptor Modulators
Cyclin-Dependent Kinases
MCF-7 Cells
Cells
Breast Neoplasms