If you made any changes in Pure these will be visible here soon.

Research Output

  • 40 Article
  • 1 Conference contribution
  • 1 Review article
Filter
Article
2020

Multi-omic analysis of subtype evolution and heterogeneity in high-grade serous ovarian carcinoma

Geistlinger, L., Oh, S., Ramos, M., Schiffer, L., LaRue, R. S., Henzler, C. M., Munro, S. A., Daughters, C., Nelson, A. C., Winterhoff, B. J., Chang, Z., Talukdar, S., Shetty, M., Mullany, S. A., Morgan, M., Parmigiani, G., Birrer, M. J., Qin, L-X., Riester, M., Starr, T. K. & 1 others, Waldron, L., Aug 3 2020, In : Cancer Research.

Research output: Contribution to journalArticle

Neonatal respiratory failure due to novel compound heterozygous mutations in the ABCA3 lipid transporter

Oltvai, Z. N., Smith, E. A., Wiens, K., Nogee, L. M., Luquette, M., Nelson, A. C. & Wikenheiser-Brokamp, K. A., Jun 1 2020, In : Cold Spring Harbor Molecular Case Studies. 6, 3

Research output: Contribution to journalArticle

Open Access

Pale (Clear) Cell Acanthoma of the Palate

Argyris, P. P., Ho, D., Nelson, A. C. & Koutlas, I. G., Jun 1 2020, In : Head and Neck Pathology. 14, 2, p. 535-541 7 p.

Research output: Contribution to journalArticle

Postpartum breast cancer progression is driven by semaphorin 7a-mediated invasion and survival

Tarullo, S. E., Hill, R. C., Hansen, K. C., Behbod, F., Borges, V. F., Nelson, A. C. & Lyons, T. R., Feb 4 2020, In : Oncogene. 39, 13, p. 2772-2785 14 p.

Research output: Contribution to journalArticle

1 Scopus citations

RAS internal tandem duplication disrupts GTPase-activating protein (GAP) binding to activate oncogenic signaling

Nelson, A. C., Turbyville, T. J., Dharmaiah, S., Rigby, M., Yang, R., Wang, T-Y., Columbus, J., Stephens, R., Taylor, T., Sciacca, D., Onsongo, G., Sarver, A., Subramanian, S., Nissley, D. V., Simanshu, D. K. & Lou, E., Jul 10 2020, In : The Journal of biological chemistry. 295, 28, p. 9335-9348 14 p.

Research output: Contribution to journalArticle

Tissue-resident macrophages promote extracellular matrix homeostasis in the mammary gland stroma of nulliparous mice

Wang, Y., Chaffee, T. S., Larue, R. S., Huggins, D. N., Witschen, P. M., Ibrahim, A. M., Nelson, A. C., Machado, H. L. & Schwertfeger, K. L., Jun 2020, In : eLife. 9, p. 1-27 27 p., e57438.

Research output: Contribution to journalArticle

Open Access
Open Access
2019

Analyses of molecular and histopathologic features and expression of PRAME by immunohistochemistry in mucosal melanomas

Toyama, A., Siegel, L., Nelson, A. C., Najmuddin, M., Bu, L., LaRue, R., Henzler, C., Caicedo-Granados, E., Giubellino, A. & Li, F., Dec 1 2019, In : Modern Pathology. 32, 12, p. 1727-1733 7 p.

Research output: Contribution to journalArticle

Open Access

JAK/STAT inhibition in macrophages promotes therapeutic resistance by inducing expression of protumorigenic factors

Irey, E. A., Lassiter, C. M., Brady, N. J., Chuntova, P., Wang, Y., Knutson, T. P., Henzler, C., Chaffee, T. S., Vogel, R. I., Nelson, A. C., Farrar, M. A. & Schwertfeger, K. L., Jun 18 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 25, p. 12442-12451 10 p.

Research output: Contribution to journalArticle

Open Access
6 Scopus citations

Next generation sequencing for clinical diagnostics: Five year experience of an academic laboratory

Hartman, P., Beckman, K. B., Silverstein, K. A., Yohe, S. L., Schomaker, M., Henzler, C., Onsongo, G., Lam, H. C., Munro, S. A., Daniel, J., Billstein, B., Deshpande, A., Hauge, A., Mroz, P. A., Lee, W., Holle, J., Wiens, K., Karnuth, K., Kemmer, T., Leary, M. & 6 others, Michel, S., Pohlman, L., Thayanithy, V., Nelson, A. C., Bower, M. & Thyagarajan, B., Jun 2019, In : Molecular Genetics and Metabolism Reports. 19, 100464.

Research output: Contribution to journalArticle

Open Access
5 Scopus citations

Solitary oral epidermolytic acanthoma: Case report of a rarely diagnosed entity

Argyris, P. P., Slama, Z. M., Nelson, A. C. & Koutlas, I. G., Dec 2019, In : Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology. 128, 6, p. e208-e213

Research output: Contribution to journalArticle

Somatic Mosaicism in a Male Patient With X-linked Alport Syndrome

Bu, L., Chen, J., Nelson, A. C., Katz, A., Kashtan, C. E., Kim, Y. & Pierpont, M. E., Jul 2019, In : Kidney International Reports. 4, 7, p. 1031-1035 5 p.

Research output: Contribution to journalArticle

Open Access
2018

Chemotherapy-Induced Tunneling Nanotubes Mediate Intercellular Drug Efflux in Pancreatic Cancer

Desir, S., O'Hare, P., Vogel, R. I., Sperduto, W., Sarkari, A., Dickson, E. L., Wong, P., Nelson, A. C., Fong, Y., Steer, C. J., Subramanian, S. & Lou, E., Dec 1 2018, In : Scientific reports. 8, 1, 9484.

Research output: Contribution to journalArticle

Open Access
23 Scopus citations

Genomics of clonal evolution in a case of essential thrombocythemia

Rashidi, A., Nelson, A. C., Linden, M. A., Weisdorf, D. J., Dolan, M. M. & Ustun, C., Feb 1 2018, In : Leukemia and Lymphoma. 59, 2, p. 497-500 4 p.

Research output: Contribution to journalArticle

1 Scopus citations

Optimal detection of clinically relevant mutations in colorectal carcinoma: Sample pooling overcomes intra-tumoral heterogeneity

Nelson, A. C., Boone, J., Cartwright, D., Thyagarajan, B., Kincaid, R., Lambert, A. P., Karnuth, K., Henzler, C. & Yohe, S., Feb 1 2018, In : Modern Pathology. 31, 2, p. 343-349 7 p.

Research output: Contribution to journalArticle

Open Access
6 Scopus citations

Optimization of a microfluidics-based next generation sequencing assay for clinical oncology diagnostics

Henzler, C., Schomaker, M., Yang, R., Lambert, A. P., Larue, R., Kincaid, R., Beckman, K., Kemmer, T., Wilson, J., Yohe, S., Thyagarajan, B. & Nelson, A. C., May 1 2018, In : Annals of Translational Medicine. 6, 9, p. 162-162

Research output: Contribution to journalArticle

2017

Buccal epithelial cells display somatic, bone marrow-derived CALR mutation

Gilles, S. R., Baughn, L. B., Schomaker, M. L., Courville, E. L., Nelson, A. C. & Sachs, Z., Nov 28 2017, In : Blood Advances. 1, 25, p. 2302-2306 5 p.

Research output: Contribution to journalArticle

Open Access
Open Access
4 Scopus citations
2016

ADAM17 in tumor associated leukocytes regulates inflammatory mediators and promotes mammary tumor formation

Bohrer, L. R., Chaffee, T. S., Chuntova, P., Brady, N. J., Witschen, P. M., Kemp, S. E., Nelson, A. C., Walcheck, B. & Schwertfeger, K. L., Jul 2016, In : Genes and Cancer. 7, 7-8, p. 240-253 14 p.

Research output: Contribution to journalArticle

Open Access

Complete and sustained response of adult medulloblastoma to first-line sonic hedgehog inhibition with vismodegib

Lou, E., Schomaker, M., Wilson, J. D., Ahrens, M., Dolan, M. & Nelson, A. C., Oct 2 2016, In : Cancer Biology and Therapy. 17, 10, p. 1010-1016 7 p.

Research output: Contribution to journalArticle

Open Access
9 Scopus citations
Open Access
22 Scopus citations

EBV-negative monomorphic B-cell post-transplant lymphoproliferative disorders are pathologically distinct from EBV-positive cases and frequently contain TP53 mutations

Courville, E. L., Yohe, S., Chou, D., Nardi, V., Lazaryan, A., Thakral, B., Nelson, A. C., Ferry, J. A. & Sohani, A. R., Oct 1 2016, In : Modern Pathology. 29, 10, p. 1200-1211 12 p.

Research output: Contribution to journalArticle

9 Scopus citations

Semaphorin 7a exerts pleiotropic effects to promote breast tumor progression

Black, S. A., Nelson, A. C., Gurule, N. J., Futscher, B. W. & Lyons, T. R., Sep 29 2016, In : Oncogene. 35, 39, p. 5170-5178 9 p.

Research output: Contribution to journalArticle

Open Access
23 Scopus citations
2015

Criteria for Clinical Reporting of Variants from a Broad Target Capture NGS Assay without Sanger Verification.

Nelson, A. C., Bower, M., Baughn, L., Henzler, C., Onsongo, G., Silverstein, K. A., Schomaker, M., Deshpande, A., Beckman, K., Yohe, S. L. & Thyagarajan, B., 2015, In : JSM Biomarkers. 2, 1

Research output: Contribution to journalArticle

Epiregulin contributes to breast tumorigenesis through regulating matrix metalloproteinase 1 and promoting cell survival

Farooqui, M., Bohrer, L. R., Brady, N. J., Chuntova, P., Kemp, S. E., Wardwell, C. T., Nelson, A. C. & Schwertfeger, K. L., Jul 29 2015, In : Molecular Cancer. 14, 1, 138.

Research output: Contribution to journalArticle

11 Scopus citations
7 Scopus citations

Localized juvenile spongiotic gingival hyperplasia featuring unusual p16INK4A labeling and negative human papillomavirus status by polymerase chain reaction

Argyris, P. P., Nelson, A. C., Papanakou, S., Merkourea, S., Tosios, K. I. & Koutlas, I. G., Jan 1 2015, In : Journal of Oral Pathology and Medicine. 44, 1, p. 37-44 8 p.

Research output: Contribution to journalArticle

11 Scopus citations
24 Scopus citations
2014

Pulmonary tumor thrombotic microangiopathy associated with right ventricular rupture and hemopericardium: A case report

Kamouh, A., Nelson, A. C., Vats, S., Powell, R. & Missov, E., Jun 2014, In : Journal of Cardiology Cases. 9, 6, p. 230-232 3 p.

Research output: Contribution to journalArticle

2013

Recurrent anaplastic medulloblastoma in cerebrospinal fluid after autologous hematopoietic stem cell transplant

Nelson, A. C., Singh, C., Clark, H. B. & Pambuccian, S. E., Nov 1 2013, In : Diagnostic Cytopathology. 41, 11, p. 980-985 6 p.

Research output: Contribution to journalArticle

2 Scopus citations
2012
8 Scopus citations
2010

AKT regulates BRCA1 stability in response to hormone signaling

Nelson, A. C., Lyons, T. R., Young, C. D., Hansen, K. C., Anderson, S. M. & Holt, J. T., May 5 2010, In : Molecular and Cellular Endocrinology. 319, 1-2, p. 129-142 14 p.

Research output: Contribution to journalArticle

19 Scopus citations

Impact of RING and BRCT domain mutations on BRCA1 protein stability, localization and recruitment to DNA damage

Nelson, A. C. & Holt, J. T., Jul 2010, In : Radiation research. 174, 1, p. 1-13 13 p.

Research output: Contribution to journalArticle

18 Scopus citations
2009

Oestrogen-mediated phosphorylation and stabilization of BRCA2 protein in breast

Malone, J. L., Nelson, A. C., Lieberman, R., Anderson, S. & Holt, J. T., Feb 2009, In : Journal of Pathology. 217, 3, p. 380-388 9 p.

Research output: Contribution to journalArticle

14 Scopus citations
2000

DNA repair is activated in early stages of p53-induced apoptosis

Geske, F. J., Nelson, A. C., Lieberman, R., Strange, R., Sun, T. & Gerschenson, L. E., Apr 2000, In : Cell Death and Differentiation. 7, 4, p. 393-401 9 p.

Research output: Contribution to journalArticle

43 Scopus citations