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Research Output 1982 2019

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Article
2019
3 Citations (Scopus)
Natural Killer Cells
Ovarian Neoplasms
Cytokines
Immunosuppressive Agents
Ascites
1 Citation (Scopus)

Development of a multiplexed giant magnetoresistive biosensor array prototype to quantify ovarian cancer biomarkers

Klein, T., Wang, W., Yu, L., Wu, K., Boylan, K. L., Vogel, R. I., Skubitz, A. P. & Wang, J., Feb 1 2019, In : Biosensors and Bioelectronics. 126, p. 301-307 7 p.

Research output: Contribution to journalArticle

Biosensing Techniques
Tumor Biomarkers
Computer programming
Biosensors
Ovarian Neoplasms

Simultaneous measurement of 92 serum protein biomarkers for the development of a multiprotein classifier for ovarian cancer detection

Skubitz, A. P., Boylan, K. L., Geschwind, K., Cao, Q., Starr, T., Geller, M. A., Celestino, J., Bast, R. C., Lu, K. H. & Koopmeiners, J., Mar 1 2019, In : Cancer Prevention Research. 12, 3, p. 171-183 13 p.

Research output: Contribution to journalArticle

Ovarian Neoplasms
Blood Proteins
Biomarkers
Proteins
Sensitivity and Specificity
2018
Open Access
Papanicolaou Test
Microbiota
Fixatives
Protein Databases
Proteins
2017
3 Citations (Scopus)

A multiplex platform for the identification of ovarian cancer biomarkers

Boylan, K. L., Geschwind, K., Koopmeiners, J., Geller, M. A., Starr, T. & Skubitz, A. P., Oct 10 2017, In : Clinical Proteomics. 14, 1, 34.

Research output: Contribution to journalArticle

Open Access
Biomarkers
Tumor Biomarkers
Ovarian Neoplasms
Assays
ROC Curve
12 Citations (Scopus)

Ectodomain shedding of the cell adhesion molecule Nectin-4 in ovarian cancer is mediated by ADAM10 and ADAM17

Buchanan, P. C., Boylan, K. L., Walcheck, B., Heinze, R., Geller, M. A., Argenta, P. A. & Skubitz, A. P., Apr 14 2017, In : Journal of Biological Chemistry. 292, 15, p. 6339-6351 13 p.

Research output: Contribution to journalArticle

Open Access
Cell Adhesion Molecules
Ovarian Neoplasms
Ascites
Disintegrins
Metalloproteases
29 Citations (Scopus)

IL-15 super-agonist (ALT-803) enhances natural killer (NK) cell function against ovarian cancer

Felices, M., Chu, S., Kodal, B., Bendzick, L., Ryan, C., Lenvik, A. J., Boylan, K. L. M., Wong, H. C., Skubitz, A. P. N., Miller, J. S. & Geller, M. A., Jun 1 2017, In : Gynecologic Oncology. 145, 3, p. 453-461 9 p.

Research output: Contribution to journalArticle

Open Access
Interleukin-15
Natural Killer Cells
Ovarian Neoplasms
Ascites
ALT-803
9 Citations (Scopus)

The expression of Nectin-4 on the surface of ovarian cancer cells alters their ability to adhere, migrate, aggregate, and proliferate

Boylan, K. L., Buchanan, P. C., Manion, R. D., Shukla, D. M., Braumberger, K., Bruggemeyer, C. & Skubitz, A. P., Jan 1 2017, In : Oncotarget. 8, 6, p. 9717-9738 22 p.

Research output: Contribution to journalArticle

Open Access
Ovarian Neoplasms
nectins
Cell Line
Epithelial-Mesenchymal Transition
Cell Adhesion Molecules
2016
3 Citations (Scopus)
Gastrointestinal Stromal Tumors
Gene expression
Tumors
Genes
Gene Expression
7 Citations (Scopus)

Preservation of Biospecimens at Ambient Temperature: Special Focus on Nucleic Acids and Opportunities for the Biobanking Community

Muller, R., Betsou, F., Barnes, M. G., Harding, K., Bonnet, J., Kofanova, O., Crowe, J. H., Benson, E., Bulla, A., Chuaqui, R., Clements, J. A., Coppola, D., De Souza, Y., De Wilde, A., Eliason, J., Glazer, B., Grizzle, W., Gunter, E., Hodgkinson, V., Hubel, A. & 11 others, Kokkat, T., Koppandi, I., Mackenzie-Dodds, J., Pugh, R., Rajasekhar, V., Shea, K., Skubitz, A., Sobel, M., Somiari, S., Tybring, G. & Valyi-Nagy, K., Apr 1 2016, In : Biopreservation and Biobanking. 14, 2, p. 89-98 10 p.

Research output: Contribution to journalArticle

Nucleic Acids
Biological Preservation
Temperature
Accreditation
Risk Management
2014
5 Citations (Scopus)

A feasibility study to identify proteins in the residual Pap test fluid of women with normal cytology by mass spectrometry-based proteomics

Boylan, K. L. M., Afiuni-Zadeh, S., Geller, M. A., Hickey, K., Griffin, T. J., Pambuccian, S. E. & Skubitz, A. P. N., Jul 14 2014, In : Clinical Proteomics. 11, 1, 30.

Research output: Contribution to journalArticle

Cytology
Papanicolaou Test
Feasibility Studies
Proteomics
Mass spectrometry
7 Citations (Scopus)

Expression of FAP, ADAM12, WISP1, and SOX11 is heterogeneous in aggressive fibromatosis and spatially relates to the histologic features of tumor activity

Misemer, B. S., Skubitz, A. P. N., Carlos Manivel, J., Schmechel, S. C., Cheng, E. Y., Henriksen, J. C., Koopmeiners, J. S., Corless, C. L. & Skubitz, K. M., Feb 1 2014, In : Cancer medicine. 3, 1, p. 81-90 10 p.

Research output: Contribution to journalArticle

Aggressive Fibromatosis
Neoplasms
Immunohistochemistry
Chromatin
Proteins
6 Citations (Scopus)

Gene expression identifies heterogeneity of metastatic behavior among high-grade non-translocation associated soft tissue sarcomas

Skubitz, K. M., Skubitz, A. P., Xu, W. W., Luo, X., Lagarde, P., Coindre, J. M. & Chibon, F., Jun 20 2014, In : Journal of Translational Medicine. 12, 1, 176.

Research output: Contribution to journalArticle

Gene expression
Sarcoma
Tissue
Gene Expression
Cluster Analysis
2013
57 Citations (Scopus)

Identification of evidence-based biospecimen quality-control tools: A report of the international society for biological and environmental repositories (ISBER) biospecimen science working group

Betsou, F., Gunter, E., Clements, J., De Souza, Y., Goddard, K. A. B., Guadagni, F., Yan, W., Skubitz, A., Somiari, S., Yeadon, T. & Chuaqui, R., Jan 1 2013, In : Journal of Molecular Diagnostics. 15, 1, p. 3-16 14 p.

Research output: Contribution to journalArticle

Quality Control
CD40 Ligand
Serum
Vascular Endothelial Growth Factor A
Reference Values
7 Citations (Scopus)

Isothermal vitrification methodology development for non-cryogenic storage of archival human sera

Less, R., Boylan, K. L., Skubitz, A. P. & Aksan, A., Apr 1 2013, In : Cryobiology. 66, 2, p. 176-185 10 p.

Research output: Contribution to journalArticle

Vitrification
vitrification
Trehalose
Dextrans
Serum
49 Citations (Scopus)

Targeting CD133 in an in vivo ovarian cancer model reduces ovarian cancer progression

Skubitz, A. P. N., Taras, E. P., Boylan, K. L. M., Waldron, N. N., Oh, S., Panoskaltsis-Mortari, A. & Vallera, D. A., Sep 1 2013, In : Gynecologic oncology. 130, 3, p. 579-587 9 p.

Research output: Contribution to journalArticle

Neoplastic Stem Cells
Ovarian Neoplasms
Neoplasms
Immunotoxins
Recurrence
2012
13 Citations (Scopus)

Establishment, Characterization and Downstream Application of Primary Ovarian Cancer Cells Derived from Solid Tumors

Sueblinvong, T., Ghebre, R. G., Iizuka, Y., Pambuccian, S. E., Vogel, R. I., Skubitz, A. P. & Bazzaro, M., Nov 30 2012, In : PloS one. 7, 11, e50519.

Research output: Contribution to journalArticle

ovarian neoplasms
Ovarian Neoplasms
Tumors
Cells
neoplasms
15 Citations (Scopus)

Gene expression identifies heterogeneity of metastatic propensity in high-grade soft tissue sarcomas

Skubitz, K. M., Francis, P., Skubitz, A. P., Luo, X. & Nilbert, M., Sep 1 2012, In : Cancer. 118, 17, p. 4235-4243 9 p.

Research output: Contribution to journalArticle

Sarcoma
Gene Expression
Genes
Cluster Analysis
Aggressive Fibromatosis
166 Citations (Scopus)

Quantitative comparison of immunohistochemical staining measured by digital image analysis versus pathologist visual scoring

Rizzardi, A. E., Johnson, A. T., Vogel, R. I., Pambuccian, S. E., Henriksen, J., Skubitz, A. P., Metzger, G. & Schmechel, S. C., Apr 19 2012, In : Diagnostic Pathology. 7, 1, 42.

Research output: Contribution to journalArticle

Staining and Labeling
Software
Carcinoma
Paraffin
Formaldehyde
13 Citations (Scopus)

Short-term stability study of RNA at room temperature

Mathay, C., Yan, W., Chuaqui, R., Skubitz, A. P. N., Jeon, J. P., Fall, N., Betsou, F. & Barnes, M., Dec 1 2012, In : Biopreservation and Biobanking. 10, 6, p. 532-542 11 p.

Research output: Contribution to journalArticle

RNA Stability
RNA
Temperature
Real-Time Polymerase Chain Reaction
Recovery
7 Citations (Scopus)

Stabilization of tissue specimens for pathological examination and biomedical research

Unhale, S. A., Skubitz, A. P., Solomon, R. & Hubel, A., Dec 1 2012, In : Biopreservation and Biobanking. 10, 6, p. 493-500 8 p.

Research output: Contribution to journalArticle

Biomedical Research
Stabilization
Tissue
Tissue Preservation
Formaldehyde
6 Citations (Scopus)

The ISBER Best Practices: Insight from the Editors of the Third Edition

Vaught, J., Campbell, L. D., Betsou, F., Garcia, D. L., Pugh, R. S., Sexton, K. C. & Skubitz, A. P. N., Apr 1 2012, In : Biopreservation and Biobanking. 10, 2, p. 76-78 3 p.

Research output: Contribution to journalArticle

Practice Guidelines
2011
5 Citations (Scopus)

Biorepository proficiency testing for the quality control of biospecimens for the global biobanking community

Poloni, F., Ashton, G., Coppola, D., De Souza, Y., De Wilde, A. M., Douglas, J., Eliason, J., Guadagni, F., Gunter, E., Kofanova, O., Lehmann, S., Mathay, C., Shea, K., Sobel, M. E., Tybring, G., Zink, M., Betsou, F., Barnes, M., De Witt, B., Glazer, B. & 5 others, Jeon, J. P., Larson, C., Peeters, B., Skubitz, A. & Yan, W., Dec 1 2011, In : Biopreservation and Biobanking. 9, 4, p. 415-417 3 p.

Research output: Contribution to journalArticle

25 Citations (Scopus)

Claudin 4 is differentially expressed between ovarian cancer subtypes and plays a role in spheroid formation

Boylan, K. L., Misemer, B., DeRycke, M. S., Andersen, J. D., Harrington, K. M., Kalloger, S. E., Gilks, C. B., Pambuccian, S. E. & Skubitz, A. P., Jan 1 2011, In : International journal of molecular sciences. 12, 2, p. 1334-1358 25 p.

Research output: Contribution to journalArticle

Claudin-4
spheroids
Ovarian Neoplasms
cancer
Tissue
16 Citations (Scopus)

Mathematical prognostic biomarker models for treatment response and survival in epithelial ovarian cancer

Nikas, J. B., Boylan, K. L. M., Skubitz, A. P. N. & Low, W. C., Nov 14 2011, In : Cancer Informatics. 10, p. 233-247 15 p.

Research output: Contribution to journalArticle

Biomarkers
Drug Therapy
Survival
Gene Regulatory Networks
Survivors
34 Citations (Scopus)

State of the art in preservation of fluid biospecimens

Hubel, A., Aksan, A., Skubitz, A. P., Wendt, C. H. & Zhong, X., Sep 1 2011, In : Biopreservation and Biobanking. 9, 3, p. 237-244 8 p.

Research output: Contribution to journalArticle

Biomarkers
Fluids
Stabilization
Bronchoalveolar Lavage Fluid
Cerebrospinal fluid
3 Citations (Scopus)

Two new synthetic peptides from the N-domain of CEACAM1 (CD66a) stimulate neutrophil adhesion to endothelial cells.

Skubitz, K. M. & Skubitz, A. P., Jul 5 2011, In : Biopolymers. 96, 1, p. 25-31 7 p.

Research output: Contribution to journalArticle

Endothelial cells
Peptides
Neutrophils
Adhesion
Endothelial Cells
2010
50 Citations (Scopus)

Identification of candidate biomarkers in ovarian cancer serum by depletion of highly abundant proteins and differential in-gel electrophoresis

Andersen, J. D., Boylan, K. L., Xue, F. S., Anderson, L. B., Witthuhn, B. A., Markowski, T. W., Higgins, L. & Skubitz, A. P., Feb 1 2010, In : Electrophoresis. 31, 4, p. 599-610 12 p.

Research output: Contribution to journalArticle

Biomarkers
Electrophoresis
Ovarian Neoplasms
Gels
Serum
49 Citations (Scopus)

Leucine-rich alpha-2-glycoprotein-1 is upregulated in sera and tumors of ovarian cancer patients

Andersen, J. D., Boylan, K. L., Jemmerson, R., Geller, M. A., Misemer, B., Harrington, K. M., Weivoda, S., Witthuhn, B. A., Argenta, P. A., Vogel, R. I. & Skubitz, A. P., Oct 14 2010, In : Journal of Ovarian Research. 3, 1, 21.

Research output: Contribution to journalArticle

Leucine
Ovarian Neoplasms
Glycoproteins
Serum
Neoplasms
94 Citations (Scopus)

Nectin 4 overexpression in ovarian cancer tissues and serum: Potential role as a serum biomarker

DeRycke, M. S., Pambuccian, S. E., Gilks, C. B., Kalloger, S. E., Ghidouche, A., Lopez, M., Bliss, R. L., Geller, M. A., Argenta, P. A., Harrington, K. M. & Skubitz, A. P., Nov 1 2010, In : American Journal of Clinical Pathology. 134, 5, p. 835-845 11 p.

Research output: Contribution to journalArticle

Ovarian Neoplasms
Biomarkers
Serum
Female Genital Diseases
Reverse Transcriptase Polymerase Chain Reaction
32 Citations (Scopus)

Quantitative proteomic analysis by iTRAQ® for the identification of candidate biomarkers in ovarian cancer serum

Boylan, K. L., Andersen, J. D., Anderson, L. B., Higgins, L. & Skubitz, A. P., Jun 14 2010, In : Proteome Science. 8, 31.

Research output: Contribution to journalArticle

Biomarkers
Proteomics
Ovarian Neoplasms
Blood Proteins
Serum
2009
30 Citations (Scopus)
Endothelial cells
Neutrophils
Adhesion
Endothelial Cells
Tumors
23 Citations (Scopus)

S100A1 expression in ovarian and endometrial endometrioid carcinomas is a prognostic indicator of relapse-free survival

DeRycke, M. S., Andersen, J. D., Harrington, K. M., Pambuccian, S. E., Kalloger, S. E., Boylan, K. L., Argenta, P. A. & Skubitz, A. P., Dec 1 2009, In : American journal of clinical pathology. 132, 6, p. 846-856 11 p.

Research output: Contribution to journalArticle

Endometrioid Carcinoma
Endometrial Neoplasms
Ovarian Neoplasms
Recurrence
Survival
2008
26 Citations (Scopus)

Early detection of ovarian cancer using group biomarkers

Tchagang, A. B., Tewfik, A. H., DeRycke, M. S., Skubitz, K. M. & Skubitz, A. P., Jan 1 2008, In : Molecular Cancer Therapeutics. 7, 1, p. 27-37 11 p.

Research output: Contribution to journalArticle

Early Detection of Cancer
Ovarian Neoplasms
Biomarkers
Gene Expression
Genes
37 Citations (Scopus)
Transcriptome
Gene expression
Sarcoma
Tumors
Genes
2006

A differential biclustering algorithm for comparative analysis of gene expression

Tchagang, A. B., Tewfik, A. H., Skubitz, A. P. & Skubitz, K. M., Dec 1 2006, In : European Signal Processing Conference.

Research output: Contribution to journalArticle

Gene expression
Genes
Parallel algorithms
Tissue
27 Citations (Scopus)

Differential gene expression identifies subgroups of ovarian carcinoma

Skubitz, A. P., Pambuccian, S. E., Argenta, P. A. & Skubitz, K. M., Jan 1 2006, In : Translational Research. 148, 5, p. 223-248 26 p.

Research output: Contribution to journalArticle

Gene expression
Genes
Carcinoma
Gene Expression
Tissue
30 Citations (Scopus)

Differential gene expression identifies subgroups of renal cell carcinoma

Skubitz, K. M., Zimmerman, W., Kammerer, R., Pambuccian, S. & Skubitz, A. P. N., May 1 2006, In : Journal of Laboratory and Clinical Medicine. 147, 5, p. 250-267 18 p.

Research output: Contribution to journalArticle

Renal Cell Carcinoma
Gene expression
Genes
Cells
Gene Expression
91 Citations (Scopus)

Disaggregation and invasion of ovarian carcinoma ascites spheroids

Burleson, K. M., Boente, M. P., Pambuccian, S. E. & Skubitz, A. P., Jan 24 2006, In : Journal of Translational Medicine. 4, 6.

Research output: Contribution to journalArticle

Ascites
Monolayers
Assays
Carcinoma
Tumors
2005
29 Citations (Scopus)

Differential gene expression in liposarcoma, lipoma, and adipose tissue

Skubitz, K. M., Cheng, E. Y., Clohisy, D. R., Thompson, R. C. & Skubitz, A. P., Apr 18 2005, In : Cancer Investigation. 23, 2, p. 105-118 14 p.

Research output: Contribution to journalArticle

Liposarcoma
Lipoma
Adipose Tissue
Gene Expression
Sarcoma
101 Citations (Scopus)

Ovarian carcinoma spheroids disaggregate on type I collagen and invade live human mesothelial cell monolayers

Burleson, K. M., Hansen, L. K. & Skubitz, A. P., Jan 1 2005, In : Clinical and Experimental Metastasis. 21, 8, p. 685-697 13 p.

Research output: Contribution to journalArticle

Collagen Type I
Carcinoma
Integrins
Extracellular Matrix Proteins
Ascites
7 Citations (Scopus)
Protein Kinases
Melanoma
Protein-Serine-Threonine Kinases
Adhesion
Immunoprecipitation
2004
32 Citations (Scopus)

Characterization of sarcomas by means of gene expression

Skubitz, K. M. & Skubitz, A. P., Aug 1 2004, In : Journal of Laboratory and Clinical Medicine. 144, 2, p. 78-91 14 p.

Research output: Contribution to journalArticle

Gene expression
Sarcoma
Genes
Gene Expression
Malignant Fibrous Histiocytoma
181 Citations (Scopus)

Differential gene expression in ovarian carcinoma: Identification of potential biomarkers

Hibbs, K., Skubitz, K. M., Pambuccian, S. E., Casey, R. C., Burleson, K. M., Oegema, T. R., Thiele, J. J., Grindle, S. M., Bliss, R. L. & Skubitz, A. P., Jan 1 2004, In : American Journal of Pathology. 165, 2, p. 397-414 18 p.

Research output: Contribution to journalArticle

Biomarkers
Carcinoma
Gene Expression
Genes
Claudin-4
53 Citations (Scopus)

Gene expression in aggressive fibromatosis

Skubitz, K. M. & Skubitz, A. P., Jan 1 2004, In : Journal of Laboratory and Clinical Medicine. 143, 2, p. 89-98 10 p.

Research output: Contribution to journalArticle

Aggressive Fibromatosis
Gene expression
Genes
Gene Expression
Tissue
47 Citations (Scopus)

Gene expression in giant-celltumors

Skubitz, K. M., Cheng, E. Y., Clohisy, D. R., Thompson, R. C. & Skubitz, A. P., Oct 1 2004, In : Journal of Laboratory and Clinical Medicine. 144, 4, p. 193-200 8 p.

Research output: Contribution to journalArticle

Gene expression
Genes
Gene Expression
Bone
Osteoclasts
157 Citations (Scopus)

Ovarian carcinoma ascites spheroids adhere to extracellular matrix components and mesothelial cell monolayers

Burleson, K. M., Casey, R. C., Skubitz, K. M., Pambuccian, S. E., Oegema, T. R. & Skubitz, A. P., Apr 1 2004, In : Gynecologic oncology. 93, 1, p. 170-181 12 p.

Research output: Contribution to journalArticle

Cellular Structures
Ascites
Extracellular Matrix
Carcinoma
Integrins
2003
61 Citations (Scopus)

Cell membrane glycosylation mediates the adhesion, migration, and invasion of ovarian carcinoma cells

Casey, R. C., Oegema, T. R., Skubitz, K. M., Pambuccian, S. E., Grindle, S. M. & Skubitz, A. P., Apr 14 2003, In : Clinical and Experimental Metastasis. 20, 2, p. 143-152 10 p.

Research output: Contribution to journalArticle

Glycosylation
Cell Membrane
Carcinoma
Proteoglycans
Extracellular Matrix
88 Citations (Scopus)

Differential gene expression in leiomyosarcoma

Skubitz, K. M. & Skubitz, A. P., Sep 1 2003, In : Cancer. 98, 5, p. 1029-1038 10 p.

Research output: Contribution to journalArticle

Leiomyosarcoma
Myometrium
Gene Expression
Leiomyoma
Genes
71 Citations (Scopus)

Differential gene expression in uterine leiomyoma

Skubitz, K. M. & Skubitz, A. P., May 1 2003, In : Journal of Laboratory and Clinical Medicine. 141, 5, p. 297-308 12 p.

Research output: Contribution to journalArticle

Leiomyoma
Gene expression
Myometrium
Genes
Gene Expression