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Research Output 1982 2019

2019
2 Citations (Scopus)
Natural Killer Cells
Ovarian Neoplasms
Cytokines
Immunosuppressive Agents
Ascites
Biosensing Techniques
Tumor Biomarkers
Computer programming
Biosensors
Ovarian Neoplasms
Open Access
Chemotherapy
Neoplastic Stem Cells
Macrophages
Stem cells
Sarcoma

Simultaneous measurement of 92 serum protein biomarkers for the development of a multiprotein classifier for ovarian cancer detection

Skubitz, A. P., Boylan, K. L., Geschwind, K., Cao, Q., Starr, T., Geller, M. A., Celestino, J., Bast, R. C., Lu, K. H. & Koopmeiners, J., Mar 1 2019, In : Cancer Prevention Research. 12, 3, p. 171-183 13 p.

Research output: Contribution to journalArticle

Ovarian Neoplasms
Blood Proteins
Biomarkers
Proteins
Sensitivity and Specificity
2018
Open Access
Papanicolaou Test
Microbiota
Fixatives
Protein Databases
Proteins
2017
2 Citations (Scopus)

A multiplex platform for the identification of ovarian cancer biomarkers

Boylan, K. L., Geschwind, K., Koopmeiners, J., Geller, M. A., Starr, T. & Skubitz, A. P., Oct 10 2017, In : Clinical Proteomics. 14, 1, 34.

Research output: Contribution to journalArticle

Open Access
Biomarkers
Tumor Biomarkers
Ovarian Neoplasms
Assays
ROC Curve
11 Citations (Scopus)

Ectodomain shedding of the cell adhesion molecule Nectin-4 in ovarian cancer is mediated by ADAM10 and ADAM17

Buchanan, P. C., Boylan, K. L., Walcheck, B., Heinze, R., Geller, M. A., Argenta, P. A. & Skubitz, A. P., Apr 14 2017, In : Journal of Biological Chemistry. 292, 15, p. 6339-6351 13 p.

Research output: Contribution to journalArticle

Open Access
Cell Adhesion Molecules
Ovarian Neoplasms
Ascites
Disintegrins
Metalloproteases
27 Citations (Scopus)

IL-15 super-agonist (ALT-803) enhances natural killer (NK) cell function against ovarian cancer

Felices, M., Chu, S., Kodal, B., Bendzick, L., Ryan, C., Lenvik, A. J., Boylan, K. L. M., Wong, H. C., Skubitz, A. P. N., Miller, J. S. & Geller, M. A., Jun 1 2017, In : Gynecologic Oncology. 145, 3, p. 453-461 9 p.

Research output: Contribution to journalArticle

Open Access
Interleukin-15
Natural Killer Cells
Ovarian Neoplasms
Ascites
ALT-803

Management of Patient Samples

Berliner, K. E. & Skubitz, A. P., Nov 17 2017, Principles and Practice of Clinical Research. Elsevier, p. 559-569 11 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Specimen Handling
Research
Reproducibility of Results
Research Personnel
Outcome Assessment (Health Care)
1 Citation (Scopus)

Principles of cryopreservation

Hubel, A. & Skubitz, A. P., Jul 6 2017, Biobanking of Human Biospecimens: Principles and Practice. Springer International Publishing, p. 1-21 21 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Cryopreservation
Freezing
Therapeutics
6 Citations (Scopus)

The expression of Nectin-4 on the surface of ovarian cancer cells alters their ability to adhere, migrate, aggregate, and proliferate

Boylan, K. L., Buchanan, P. C., Manion, R. D., Shukla, D. M., Braumberger, K., Bruggemeyer, C. & Skubitz, A. P., Jan 1 2017, In : Oncotarget. 8, 6, p. 9717-9738 22 p.

Research output: Contribution to journalArticle

Open Access
Ovarian Neoplasms
nectins
Cell Line
Epithelial-Mesenchymal Transition
Cell Adhesion Molecules
2016
3 Citations (Scopus)
Gastrointestinal Stromal Tumors
Gene expression
Tumors
Genes
Gene Expression
6 Citations (Scopus)

Preservation of Biospecimens at Ambient Temperature: Special Focus on Nucleic Acids and Opportunities for the Biobanking Community

Muller, R., Betsou, F., Barnes, M. G., Harding, K., Bonnet, J., Kofanova, O., Crowe, J. H., Benson, E., Bulla, A., Chuaqui, R., Clements, J. A., Coppola, D., De Souza, Y., De Wilde, A., Eliason, J., Glazer, B., Grizzle, W., Gunter, E., Hodgkinson, V., Hubel, A. & 11 othersKokkat, T., Koppandi, I., Mackenzie-Dodds, J., Pugh, R., Rajasekhar, V., Shea, K., Skubitz, A., Sobel, M., Somiari, S., Tybring, G. & Valyi-Nagy, K., Apr 1 2016, In : Biopreservation and Biobanking. 14, 2, p. 89-98 10 p.

Research output: Contribution to journalArticle

Nucleic Acids
Biological Preservation
Temperature
Accreditation
Risk Management
2014
5 Citations (Scopus)
Cytology
Papanicolaou Test
Feasibility Studies
Proteomics
Mass spectrometry
4 Citations (Scopus)

Expression of FAP, ADAM12, WISP1, and SOX11 is heterogeneous in aggressive fibromatosis and spatially relates to the histologic features of tumor activity

Misemer, B. S., Skubitz, A. P. N., Carlos Manivel, J., Schmechel, S. C., Cheng, E. Y., Henriksen, J. C., Koopmeiners, J. S., Corless, C. L. & Skubitz, K. M., Feb 1 2014, In : Cancer medicine. 3, 1, p. 81-90 10 p.

Research output: Contribution to journalArticle

Aggressive Fibromatosis
Neoplasms
Immunohistochemistry
Chromatin
Proteins
6 Citations (Scopus)

Gene expression identifies heterogeneity of metastatic behavior among high-grade non-translocation associated soft tissue sarcomas

Skubitz, K. M., Skubitz, A. P., Xu, W. W., Luo, X., Lagarde, P., Coindre, J. M. & Chibon, F., Jun 20 2014, In : Journal of Translational Medicine. 12, 1, 176.

Research output: Contribution to journalArticle

Gene expression
Sarcoma
Tissue
Gene Expression
Cluster Analysis
43 Citations (Scopus)

Storage of human biospecimens: Selection of the optimal storage temperature

Hubel, A., Spindler, R. & Skubitz, A. P. N., Jun 1 2014, In : Biopreservation and Biobanking. 12, 3, p. 165-175 11 p.

Research output: Contribution to journalReview article

Temperature
Biomarkers
Tissue
Literature
Fluids
2013
57 Citations (Scopus)

Identification of evidence-based biospecimen quality-control tools: A report of the international society for biological and environmental repositories (ISBER) biospecimen science working group

Betsou, F., Gunter, E., Clements, J., De Souza, Y., Goddard, K. A. B., Guadagni, F., Yan, W., Skubitz, A., Somiari, S., Yeadon, T. & Chuaqui, R., Jan 1 2013, In : Journal of Molecular Diagnostics. 15, 1, p. 3-16 14 p.

Research output: Contribution to journalArticle

Quality Control
CD40 Ligand
Serum
Vascular Endothelial Growth Factor A
Reference Values
7 Citations (Scopus)

Isothermal vitrification methodology development for non-cryogenic storage of archival human sera

Less, R., Boylan, K. L., Skubitz, A. P. & Aksan, A., Apr 1 2013, In : Cryobiology. 66, 2, p. 176-185 10 p.

Research output: Contribution to journalArticle

Vitrification
vitrification
Trehalose
Dextrans
Serum
44 Citations (Scopus)

Targeting CD133 in an in vivo ovarian cancer model reduces ovarian cancer progression

Skubitz, A. P. N., Taras, E. P., Boylan, K. L. M., Waldron, N. N., Oh, S., Panoskaltsis-Mortari, A. & Vallera, D. A., Sep 1 2013, In : Gynecologic Oncology. 130, 3, p. 579-587 9 p.

Research output: Contribution to journalArticle

Neoplastic Stem Cells
Ovarian Neoplasms
Neoplasms
Immunotoxins
Recurrence
2012
29 Citations (Scopus)

Development of the ISBER best practices for repositories: Collection, storage, retrieval and distribution of biological materials for research

Campbell, L. D., Betsou, F., Garcia, D. L., Giri, J. G., Pitt, K. E., Pugh, R. S., Sexton, K. C., Skubitz, A. P. N. & Somiari, S. B., Apr 1 2012, In : Biopreservation and Biobanking. 10, 2, p. 232-233 2 p.

Research output: Contribution to journalComment/debate

Biological materials
13 Citations (Scopus)

Establishment, Characterization and Downstream Application of Primary Ovarian Cancer Cells Derived from Solid Tumors

Sueblinvong, T., Ghebre, R. G., Iizuka, Y., Pambuccian, S. E., Vogel, R. I., Skubitz, A. P. & Bazzaro, M., Nov 30 2012, In : PLoS One. 7, 11, e50519.

Research output: Contribution to journalArticle

ovarian neoplasms
Ovarian Neoplasms
Tumors
Cells
neoplasms
14 Citations (Scopus)

Gene expression identifies heterogeneity of metastatic propensity in high-grade soft tissue sarcomas

Skubitz, K. M., Francis, P., Skubitz, A. P., Luo, X. & Nilbert, M., Sep 1 2012, In : Cancer. 118, 17, p. 4235-4243 9 p.

Research output: Contribution to journalArticle

Sarcoma
Gene Expression
Genes
Cluster Analysis
Aggressive Fibromatosis

Management of Patient Samples and Specimens

Pitt, K. E. & Skubitz, A. P., Dec 1 2012, Principles and Practice of Clinical Research. Elsevier Inc., p. 509-517 9 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

156 Citations (Scopus)

Quantitative comparison of immunohistochemical staining measured by digital image analysis versus pathologist visual scoring

Rizzardi, A. E., Johnson, A. T., Vogel, R. I., Pambuccian, S. E., Henriksen, J., Skubitz, A. P., Metzger, G. & Schmechel, S. C., Apr 19 2012, In : Diagnostic Pathology. 7, 1, 42.

Research output: Contribution to journalArticle

Staining and Labeling
Software
Carcinoma
Paraffin
Formaldehyde
13 Citations (Scopus)

Short-term stability study of RNA at room temperature

Mathay, C., Yan, W., Chuaqui, R., Skubitz, A. P. N., Jeon, J. P., Fall, N., Betsou, F. & Barnes, M., Dec 1 2012, In : Biopreservation and Biobanking. 10, 6, p. 532-542 11 p.

Research output: Contribution to journalArticle

RNA Stability
RNA
Temperature
Real-Time Polymerase Chain Reaction
Recovery
7 Citations (Scopus)

Stabilization of tissue specimens for pathological examination and biomedical research

Unhale, S. A., Skubitz, A. P., Solomon, R. & Hubel, A., Dec 1 2012, In : Biopreservation and Biobanking. 10, 6, p. 493-500 8 p.

Research output: Contribution to journalArticle

Biomedical Research
Stabilization
Tissue
Tissue Preservation
Formaldehyde
68 Citations (Scopus)

Standard preanalytical coding for biospecimens: Review and implementation of the sample PREanalytical Code (SPREC)

Lehmann, S., Guadagni, F., Moore, H., Ashton, G., Barnes, M., Benson, E., Clements, J., Koppandi, I., Coppola, D., Demiroglu, S. Y., Desouza, Y., De Wilde, A., Duker, J., Eliason, J., Glazer, B., Harding, K., Jeon, J. P., Kessler, J., Kokkat, T., Nanni, U. & 6 othersShea, K., Skubitz, A., Somiari, S., Tybring, G., Gunter, E. & Betsou, F., Aug 1 2012, In : Biopreservation and Biobanking. 10, 4, p. 366-374 9 p.

Research output: Contribution to journalReview article

Informatics
Glossaries
Documentation
Communication
Research
5 Citations (Scopus)

The ISBER Best Practices: Insight from the Editors of the Third Edition

Vaught, J., Campbell, L. D., Betsou, F., Garcia, D. L., Pugh, R. S., Sexton, K. C. & Skubitz, A. P. N., Apr 1 2012, In : Biopreservation and Biobanking. 10, 2, p. 76-78 3 p.

Research output: Contribution to journalArticle

Practice Guidelines
2011
5 Citations (Scopus)

Biorepository proficiency testing for the quality control of biospecimens for the global biobanking community

Poloni, F., Ashton, G., Coppola, D., De Souza, Y., De Wilde, A. M., Douglas, J., Eliason, J., Guadagni, F., Gunter, E., Kofanova, O., Lehmann, S., Mathay, C., Shea, K., Sobel, M. E., Tybring, G., Zink, M., Betsou, F., Barnes, M., De Witt, B., Glazer, B. & 5 othersJeon, J. P., Larson, C., Peeters, B., Skubitz, A. & Yan, W., Dec 1 2011, In : Biopreservation and Biobanking. 9, 4, p. 415-417 3 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)

Claudin 4 is differentially expressed between ovarian cancer subtypes and plays a role in spheroid formation

Boylan, K. L., Misemer, B., DeRycke, M. S., Andersen, J. D., Harrington, K. M., Kalloger, S. E., Gilks, C. B., Pambuccian, S. E. & Skubitz, A. P., Jan 1 2011, In : International journal of molecular sciences. 12, 2, p. 1334-1358 25 p.

Research output: Contribution to journalArticle

Claudin-4
spheroids
Ovarian Neoplasms
cancer
Tissue
14 Citations (Scopus)

Mathematical prognostic biomarker models for treatment response and survival in epithelial ovarian cancer

Nikas, J. B., Boylan, K. L. M., Skubitz, A. P. N. & Low, W. C., Nov 14 2011, In : Cancer Informatics. 10, p. 233-247 15 p.

Research output: Contribution to journalArticle

Biomarkers
Drug Therapy
Survival
Gene Regulatory Networks
Survivors
31 Citations (Scopus)

State of the art in preservation of fluid biospecimens

Hubel, A., Aksan, A., Skubitz, A. P., Wendt, C. H. & Zhong, X., Sep 1 2011, In : Biopreservation and Biobanking. 9, 3, p. 237-244 8 p.

Research output: Contribution to journalArticle

Biomarkers
Fluids
Stabilization
Bronchoalveolar Lavage Fluid
Cerebrospinal fluid
3 Citations (Scopus)
Endothelial cells
Peptides
Neutrophils
Adhesion
Endothelial Cells
2010
50 Citations (Scopus)

Identification of candidate biomarkers in ovarian cancer serum by depletion of highly abundant proteins and differential in-gel electrophoresis

Andersen, J. D., Boylan, K. L., Xue, F. S., Anderson, L. B., Witthuhn, B. A., Markowski, T. W., Higgins, L. & Skubitz, A. P., Feb 1 2010, In : Electrophoresis. 31, 4, p. 599-610 12 p.

Research output: Contribution to journalArticle

Biomarkers
Electrophoresis
Ovarian Neoplasms
Gels
Serum
48 Citations (Scopus)

Leucine-rich alpha-2-glycoprotein-1 is upregulated in sera and tumors of ovarian cancer patients

Andersen, J. D., Boylan, K. L., Jemmerson, R., Geller, M. A., Misemer, B., Harrington, K. M., Weivoda, S., Witthuhn, B. A., Argenta, P. A., Vogel, R. I. & Skubitz, A. P., Oct 14 2010, In : Journal of Ovarian Research. 3, 1, 21.

Research output: Contribution to journalArticle

Leucine
Ovarian Neoplasms
Glycoproteins
Serum
Neoplasms
88 Citations (Scopus)

Nectin 4 overexpression in ovarian cancer tissues and serum: Potential role as a serum biomarker

DeRycke, M. S., Pambuccian, S. E., Gilks, C. B., Kalloger, S. E., Ghidouche, A., Lopez, M., Bliss, R. L., Geller, M. A., Argenta, P. A., Harrington, K. M. & Skubitz, A. P., Nov 1 2010, In : American Journal of Clinical Pathology. 134, 5, p. 835-845 11 p.

Research output: Contribution to journalArticle

Ovarian Neoplasms
Biomarkers
Serum
Female Genital Diseases
Reverse Transcriptase Polymerase Chain Reaction
31 Citations (Scopus)

Quantitative proteomic analysis by iTRAQ® for the identification of candidate biomarkers in ovarian cancer serum

Boylan, K. L., Andersen, J. D., Anderson, L. B., Higgins, L. & Skubitz, A. P., Jun 14 2010, In : Proteome Science. 8, 31.

Research output: Contribution to journalArticle

Biomarkers
Proteomics
Ovarian Neoplasms
Blood Proteins
Serum
119 Citations (Scopus)

Standard preanalytical coding for biospecimens; Defining the sample PREanalytical code

Betsou, F., Lehmann, S., Ashton, G., Barnes, M., Benson, E. E., Coppola, D., Desouza, Y., Eliason, J., Glazer, B., Guadagni, F., Harding, K., Horsfall, D. J., Kleeberger, C., Nanni, U., Prasad, A., Shea, K., Skubitz, A., Somiari, S. & Gunter, E., Apr 1 2010, In : Cancer Epidemiology Biomarkers and Prevention. 19, 4, p. 1004-1011 8 p.

Research output: Contribution to journalComment/debate

Database Management Systems
Research
Biomarkers
2009
75 Citations (Scopus)

Human biospecimen research: Experimental protocol and quality control tools

Betsou, F., Barnes, R., Burke, T., Coppola, D., DeSouza, Y., Eliason, J., Glazer, B., Horsfall, D., Kleeberger, C., Lehmann, S., Prasad, A., Skubitz, A., Somiari, S. & Gunter, E., Apr 1 2009, In : Cancer Epidemiology Biomarkers and Prevention. 18, 4, p. 1017-1025 9 p.

Research output: Contribution to journalComment/debate

Biological Specimen Banks
Specimen Handling
Quality Control
Biomedical Research
Research Design
29 Citations (Scopus)
Endothelial cells
Neutrophils
Adhesion
Endothelial Cells
Tumors
21 Citations (Scopus)

S100A1 expression in ovarian and endometrial endometrioid carcinomas is a prognostic indicator of relapse-free survival

DeRycke, M. S., Andersen, J. D., Harrington, K. M., Pambuccian, S. E., Kalloger, S. E., Boylan, K. L., Argenta, P. A. & Skubitz, A. P., Dec 1 2009, In : American journal of clinical pathology. 132, 6, p. 846-856 11 p.

Research output: Contribution to journalArticle

Endometrioid Carcinoma
Endometrial Neoplasms
Ovarian Neoplasms
Recurrence
Survival
2008
26 Citations (Scopus)

Early detection of ovarian cancer using group biomarkers

Tchagang, A. B., Tewfik, A. H., DeRycke, M. S., Skubitz, K. M. & Skubitz, A. P., Jan 1 2008, In : Molecular Cancer Therapeutics. 7, 1, p. 27-37 11 p.

Research output: Contribution to journalArticle

Early Detection of Cancer
Ovarian Neoplasms
Biomarkers
Gene Expression
Genes
36 Citations (Scopus)
Transcriptome
Gene expression
Sarcoma
Tumors
Genes
2007
9 Citations (Scopus)

Group-biomarkers identification in ovarian carcinoma

Tchagang, A. B., Tewfik, A. H., Skubitz, A. P. & Skubitz, K. M., Aug 6 2007, 2007 IEEE International Conference on Acoustics, Speech and Signal Processing, ICASSP '07. Vol. 1. 4217086

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Biomarkers
Tissue
Genes
Gene expression
Statistical methods
2006

A differential biclustering algorithm for comparative analysis of gene expression

Tchagang, A. B., Tewfik, A. H., Skubitz, A. P. & Skubitz, K. M., Dec 1 2006, In : European Signal Processing Conference.

Research output: Contribution to journalArticle

Gene expression
Genes
Parallel algorithms
Tissue
3 Citations (Scopus)

Analysis of order preserving genes biclusters

Tchagang, A. B., Tewfik, A. H. & Skubitz, A. P., Dec 1 2006, 2006 IEEE International Workshop on Genomic Signal Processing and Statstics, GENSIPS 2006. p. 101-102 2 p. 4161797

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Gene Order
Genes
Gene
Ovarian Cancer
DNA Microarray
25 Citations (Scopus)

Differential gene expression identifies subgroups of ovarian carcinoma

Skubitz, A. P., Pambuccian, S. E., Argenta, P. A. & Skubitz, K. M., Jan 1 2006, In : Translational Research. 148, 5, p. 223-248 26 p.

Research output: Contribution to journalArticle

Gene expression
Genes
Carcinoma
Gene Expression
Tissue
30 Citations (Scopus)

Differential gene expression identifies subgroups of renal cell carcinoma

Skubitz, K. M., Zimmerman, W., Kammerer, R., Pambuccian, S. & Skubitz, A. P. N., May 1 2006, In : Journal of Laboratory and Clinical Medicine. 147, 5, p. 250-267 18 p.

Research output: Contribution to journalArticle

Renal Cell Carcinoma
Gene expression
Genes
Cells
Gene Expression
89 Citations (Scopus)

Disaggregation and invasion of ovarian carcinoma ascites spheroids

Burleson, K. M., Boente, M. P., Pambuccian, S. E. & Skubitz, A. P., Jan 24 2006, In : Journal of Translational Medicine. 4, 6.

Research output: Contribution to journalArticle

Ascites
Monolayers
Assays
Carcinoma
Tumors