Amer Alam

20052020
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Fingerprint The Fingerprint is created by mining the titles and abstracts of the person's research outputs and projects/funding awards to create an index of weighted terms from discipline-specific thesauri.

  • 7 Similar Profiles
Cations Medicine & Life Sciences
Ions Medicine & Life Sciences
Cyclic Nucleotide-Gated Cation Channels Medicine & Life Sciences
Binding Sites Medicine & Life Sciences
Molecular Sequence Data Medicine & Life Sciences
Transcobalamins Medicine & Life Sciences
P-Glycoprotein Medicine & Life Sciences
Nucleotides Medicine & Life Sciences

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Research Output 2005 2020

Measuring Lipid Transfer Protein Activity Using Bicelle-Dilution Model Membranes

Gao, Y-G., Le, T. M. L., Zhai, X., Boldyrev, I. A., Mishra, S. K., Tischer, A., Murayama, T., Nishida, A., Molotkovsky, J. G., Alam, A. & Brown, R. E., Jan 23 2020, In : Analytical Chemistry.

Research output: Contribution to journalArticle

Structure of the human lipid exporter ABCB4 in a lipid environment

Olsen, J. A., Alam, A., Kowal, J., Stieger, B. & Locher, K. P., Jan 1 2020, In : Nature Structural and Molecular Biology. 27, 1, p. 62-70 9 p.

Research output: Contribution to journalArticle

Adenosine Triphosphate
Lipids
Bile Canaliculi
Chemical and Drug Induced Liver Injury
ATP-Binding Cassette Transporters
20 Citations (Scopus)

Structural insight into substrate and inhibitor discrimination by human P-glycoprotein

Alam, A., Kowal, J., Broude, E., Roninson, I. & Locher, K. P., Feb 15 2019, In : Science. 363, 6428, p. 753-756 4 p.

Research output: Contribution to journalArticle

P-Glycoprotein
Paclitaxel
Pharmaceutical Preparations
Nucleotides
Cryoelectron Microscopy
30 Citations (Scopus)

Structure of a zosuquidar and UIC2-bound human-mouse chimeric ABCB1

Alam, A., Küng, R., Kowal, J., McLeod, R. A., Tremp, N., Broude, E. V., Roninson, I. B., Stahlberg, H. & Locher, K. P., Feb 27 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 9, p. E1973-E1982

Research output: Contribution to journalArticle

Open Access
Nucleotides
ATP-Binding Cassette Transporters
Poisons
P-Glycoprotein
Membrane Lipids
8 Citations (Scopus)

Structural basis of transcobalamin recognition by human CD320 receptor

Alam, A., Woo, J. S., Schmitz, J., Prinz, B., Root, K., Chen, F., Bloch, J. S., Zenobi, R. & Locher, K. P., Jul 14 2016, In : Nature communications. 7, 12100.

Research output: Contribution to journalArticle

Open Access
Transcobalamins
affinity
vitamins
solid phases
thermal stability