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Fingerprint The Fingerprint is created by mining the titles and abstracts of the person's research outputs and projects/funding awards to create an index of weighted terms from discipline-specific thesauri.

Autophagy Medicine & Life Sciences
Apoptosis Medicine & Life Sciences
Noxae Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Cells Chemical Compounds
Cytochromes c Medicine & Life Sciences
Proteins Medicine & Life Sciences
Caspase 9 Medicine & Life Sciences

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Projects 2004 2017

T-Lymphocytes
Glucose
nucleic acids
proteins
Leukemia
Cell Death
Proteins
Noxae
Leukemia
Oxidative Stress
Proteins
Noxae
Transgenic Mice
Glucose
Proteins

Research Output 1983 2018

  • 36 Article
  • 6 Review article
  • 4 Comment/debate
  • 1 Conference contribution
20 Citations (Scopus)

The purinergic receptor P2RX7 directs metabolic fitness of long-lived memory CD8 + T cells

Borges Da Silva, H., Beura, L. K., Wang, H., Hanse, E. A., Gore, R., Scott, M. C., Walsh, D. A., Block, K. E., Fonseca, R., Yan, Y., Hippen, K. L., Blazar, B. R., Masopust, D., Kelekar, A., Vulchanova, L., Hogquist, K. A. & Jameson, S. C., Jul 12 2018, In : Nature. 559, 7713, p. 264-268 5 p.

Research output: Contribution to journalArticle

Open Access
Purinergic Receptors
T-Lymphocytes
Adenosine Triphosphate
Immune System
Immunologic Memory

The vimentin intermediate filament network restrains regulatory T cell suppression of graft-versus-host disease

McDonald-Hyman, C., Muller, J. T., Loschi, M., Thangavelu, G., Saha, A., Kumari, S., Reichenbach, D. K., Smith, M. J., Zhang, G., Koehn, B., Lin, J., Mitchell, J. S., Fife, B. T., Panoskaltsis-Mortari, A., Feser, C. J., Kirchmeier, A. K., Osborn, M. J., Hippen, K. L., Kelekar, A., Serody, J. S. & 6 othersTurka, L. A., Munn, D. H., Chi, H., Neubert, T. A., Dustin, M. L. & Blazar, B. R., Oct 1 2018, In : Journal of Clinical Investigation. 128, 10, p. 4604-4621 18 p.

Research output: Contribution to journalArticle

Intermediate Filaments
Graft vs Host Disease
Vimentin
Regulatory T-Lymphocytes
Protein Kinase C
13 Citations (Scopus)

Cytosolic malate dehydrogenase activity helps support glycolysis in actively proliferating cells and cancer

Hanse, E. A., Ruan, C., Kachman, M., Wang, D., Lowman, X. H. & Kelekar, A., Jul 6 2017, In : Oncogene. 36, 27, p. 3915-3924 10 p.

Research output: Contribution to journalArticle

Open Access
Malate Dehydrogenase
Glycolysis
NAD
Glucose
Carbon
3 Citations (Scopus)

Erratum: Heme Binding Biguanides Target Cytochrome P450-Dependent Cancer Cell Mitochondria (Cell Chemical Biology (2017) 24(10) (1259–1275.e6) (S2451945617302830)(10.1016/j.chembiol.2017.08.009))

Guo, Z., Sevrioukova, I. F., Denisov, I. G., Zhang, X., Chiu, T. L., Thomas, D. G., Hanse, E. A., Cuellar, R. A. D., Grinkova, Y. V., Langenfeld, V. W., Swedien, D. S., Stamschror, J. D., Alvarez, J., Luna, F., Galván, A., Bae, Y. K., Wulfkuhle, J. D., Gallagher, R. I., Petricoin, E. F., Norris, B. & 17 othersFlory, C. M., Schumacher, R. J., O'Sullivan, M. G., Cao, Q., Chu, H., Lipscomb, J. D., Atkins, W. M., Gupta, K., Kelekar, A., Blair, I. A., Capdevila, J. H., Falck, J. R., Sligar, S. G., Poulos, T. L., Georg, G. I., Ambrose, E. & Potter, D. A., Oct 19 2017, In : Cell Chemical Biology. 24, 10, 1 p.

Research output: Contribution to journalComment/debate

Biguanides
Mitochondria
Heme
Cytochrome P-450 Enzyme System
Cell Biology
3 Citations (Scopus)

Heme Binding Biguanides Target Cytochrome P450-Dependent Cancer Cell Mitochondria

Guo, Z., Sevrioukova, I. F., Denisov, I. G., Zhang, X., Chiu, T. L., Thomas, D. G., Hanse, E. A., Cuellar, R. A. D., Grinkova, Y. V., Langenfeld, V. W., Swedien, D. S., Stamschror, J. D., Alvarez, J., Luna, F., Galván, A., Bae, Y. K., Wulfkuhle, J. D., Gallagher, R. I., Petricoin, E. F., Norris, B. & 17 othersFlory, C. M., Schumacher, R. J., O'Sullivan, M. G., Cao, Q., Chu, H., Lipscomb, J. D., Atkins, W. M., Gupta, K., Kelekar, A., Blair, I. A., Capdevila, J. H., Falck, J. R., Sligar, S. G., Poulos, T. L., Georg, G. I., Ambrose, E. & Potter, D. A., Oct 19 2017, In : Cell Chemical Biology. 24, 10, p. 1259-1275.e6

Research output: Contribution to journalArticle

Open Access
Biguanides
Cytochrome P-450 CYP3A
Mitochondria
Heme
Cytochrome P-450 Enzyme System