Alfonso Araque

1991 …2020

Research output per year

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Research Output

2020

Dopamine-Evoked Synaptic Regulation in the Nucleus Accumbens Requires Astrocyte Activity

Corkrum, M., Covelo, A., Lines, J., Bellocchio, L., Pisansky, M., Loke, K., Quintana, R., Rothwell, P. E., Lujan, R., Marsicano, G., Martin, E. D., Thomas, M. J., Kofuji, P. & Araque, A., Mar 18 2020, In : Neuron. 105, 6, p. 1036-1047.e5

Research output: Contribution to journalArticle

5 Scopus citations

G-Protein-Coupled Receptors in Astrocyte–Neuron Communication

Kofuji, P. & Araque, A., Jan 1 2020, (Accepted/In press) In : Neuroscience.

Research output: Contribution to journalReview article

2019

Diversity and Specificity of Astrocyte–neuron Communication

Durkee, C. A. & Araque, A., Jan 1 2019, In : Neuroscience. 396, p. 73-78 6 p.

Research output: Contribution to journalReview article

Open Access
17 Scopus citations

GABA Regulation of Burst Firing in Hippocampal Astrocyte Neural Circuit: A Biophysical Model

Liu, J., McDaid, L., Araque, A., Wade, J., Harkin, J., Karim, S., Henshall, D. C., Connolly, N. M. C., Johnson, A. P., Tyrrell, A. M., Timmis, J., Millard, A. G., Hilder, J. & Halliday, D. M., Jul 23 2019, In : Frontiers in Cellular Neuroscience. 13, 335.

Research output: Contribution to journalArticle

Open Access

G i/o protein-coupled receptors inhibit neurons but activate astrocytes and stimulate gliotransmission

Durkee, C. A., Covelo, A., Lines, J., Kofuji, P., Aguilar, J. & Araque, A., Jun 2019, In : Glia. 67, 6, p. 1076-1093 18 p.

Research output: Contribution to journalArticle

11 Scopus citations

In vivo knockdown of astroglial glutamate transporters GLT-1 and GLAST increases excitatory neurotransmission in mouse infralimbic cortex: Relevance for depressive-like phenotypes

Fullana, M. N., Covelo, A., Bortolozzi, A., Araque, A. & Artigas, F., Nov 2019, In : European Neuropsychopharmacology. 29, 11, p. 1288-1294 7 p.

Research output: Contribution to journalArticle

3 Scopus citations

Role of astrocytes, microglia, and tanycytes in brain control of systemic metabolism

García-Cáceres, C., Balland, E., Prevot, V., Luquet, S., Woods, S. C., Koch, M., Horvath, T. L., Yi, C. X., Chowen, J. A., Verkhratsky, A., Araque, A., Bechmann, I. & Tschöp, M. H., Jan 1 2019, In : Nature neuroscience. 22, 1, p. 7-14 8 p.

Research output: Contribution to journalReview article

26 Scopus citations

Swelling Gliotransmission by SWELL1 Channels

Kofuji, P. & Araque, A., May 22 2019, In : Neuron. 102, 4, p. 711-713 3 p.

Research output: Contribution to journalShort survey

Tau is required for progressive synaptic and memory deficits in a transgenic mouse model of α-synucleinopathy

Singh, B., Covelo, A., Martell-Martínez, H., Nanclares, C., Sherman, M. A., Okematti, E., Meints, J., Teravskis, P. J., Gallardo, C., Savonenko, A. V., Benneyworth, M. A., Lesne, S. E., Liao, D., Araque, A. & Lee, M. K., Oct 1 2019, In : Acta Neuropathologica. 138, 4, p. 551-574 24 p.

Research output: Contribution to journalArticle

Open Access
7 Scopus citations
2018

A53t mutant alpha-synuclein induces tau-dependent postsynaptic impairment independently of neurodegenerative changes

Teravskis, P. J., Covelo, A., Miller, E. C., Singh, B., Martell-Martínez, H. A., Benneyworth, M. A., Gallardo, C., Oxnard, B. R., Araque, A., Lee, M. K. & Liao, D., Nov 7 2018, In : Journal of Neuroscience. 38, 45, p. 9754-9767 14 p.

Research output: Contribution to journalArticle

Open Access
5 Scopus citations

Astroglial CB1 Receptors Determine Synaptic D-Serine Availability to Enable Recognition Memory

Robin, L. M., Oliveira da Cruz, J. F., Langlais, V. C., Martin-Fernandez, M., Metna-Laurent, M., Busquets-Garcia, A., Bellocchio, L., Soria-Gomez, E., Papouin, T., Varilh, M., Sherwood, M. W., Belluomo, I., Balcells, G., Matias, I., Bosier, B., Drago, F., Van Eeckhaut, A., Smolders, I., Georges, F., Araque, A. & 3 others, Panatier, A., Oliet, S. H. R. & Marsicano, G., Jun 6 2018, In : Neuron. 98, 5, p. 935-944.e5

Research output: Contribution to journalArticle

Open Access
32 Scopus citations

Neuronal activity determines distinct gliotransmitter release from a single astrocyte

Covelo, A. & Araque, A., Jan 30 2018, In : eLife. 7, e32237.

Research output: Contribution to journalArticle

Open Access
33 Scopus citations

Stimulating Astrocytes to Remember

Covelo, A. & Araque, A., Jun 28 2018, In : Cell. 174, 1, p. 12-13 2 p.

Research output: Contribution to journalShort survey

Open Access
2 Scopus citations
2017

Insulin regulates astrocytic glucose handling through cooperation with IGF-I

Fernandez, A. M., Hernandez-Garzón, E., Perez-Domper, P., Perez-Alvarez, A., Mederos, S., Matsui, T., Santi, A., Trueba-Saiz, A., García-Guerra, L., Pose-Utrilla, J., Fielitz, J., Olson, E. N., De La Rosa, R. F., Garcia, L. G., Pozo, M. A., Iglesias, T., Araque, A., Soya, H., Perea, G., Martin, E. D. & 1 others, Aleman, I. T., Jan 1 2017, In : Diabetes. 66, 1, p. 64-74 11 p.

Research output: Contribution to journalArticle

Open Access
27 Scopus citations

Neuron–astrocyte signaling is preserved in the aging brain

Gómez-Gonzalo, M., Martin-Fernandez, M., Martínez-Murillo, R., Mederos, S., Hernández-Vivanco, A., Jamison, S., Fernandez, A. P., Serrano, J., Calero, P., Futch, H. S., Corpas, R., Sanfeliu, C., Perea, G. & Araque, A., Apr 1 2017, In : Glia. 65, 4, p. 569-580 12 p.

Research output: Contribution to journalArticle

Open Access
27 Scopus citations

Synapse-specific astrocyte gating of amygdala-related behavior

Martin-Fernandez, M., Jamison, S., Robin, L. M., Zhao, Z., Martin, E. D., Aguilar, J., Benneyworth, M. A., Marsicano, G. & Araque, A., Jan 1 2017, In : Nature neuroscience. 20, 11, p. 1540-1548 9 p.

Research output: Contribution to journalArticle

Open Access
47 Scopus citations

Synapse-specific regulation revealed at single synapses is concealed when recording multiple synapses

Lines, J., Covelo, A., Gómez, R., Liu, L. & Araque, A., Nov 23 2017, In : Frontiers in Cellular Neuroscience. 11, 367.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Synaptic functions of endocannabinoid signaling in health and disease

Araque, A., Castillo, P. E., Manzoni, O. J. & Tonini, R., Sep 15 2017, In : Neuropharmacology. 124, p. 13-24 12 p.

Research output: Contribution to journalReview article

Open Access
64 Scopus citations
2016

Activity-dependent switch of gabaergic inhibition into glutamatergic excitation in astrocyte-neuron networks

Perea, G., Gómez, R., Mederos, S., Covelo, A., Ballesteros, J. J., Schlosser, L., Hernández-Vivanco, A., Martín-Fernández, M., Quintana, R., Rayan, A., Díez, A., Fuenzalida, M., Agarwal, A., Bergles, D. E., Bettler, B., Manahan-Vaughan, D., Martín, E. D., Kirchhoff, F. & Araque, A., Dec 24 2016, In : eLife. 5, DECEMBER2016, e20362.

Research output: Contribution to journalArticle

Open Access
46 Scopus citations

Lateral regulation of synaptic transmission by astrocytes

Covelo, A. & Araque, A., May 26 2016, In : Neuroscience. 323, p. 62-66 5 p.

Research output: Contribution to journalArticle

22 Scopus citations

The insulin-like growth factor I receptor regulates glucose transport by astrocytes

Hernandez-Garzón, E., Fernandez, A. M., Perez-Alvarez, A., Genis, L., Bascuñana, P., Fernandez de la Rosa, R., Delgado, M., Angel Pozo, M., Moreno, E., McCormick, P. J., Santi, A., Trueba-Saiz, A., Garcia-Caceres, C., Tschöp, M. H., Araque, A., Martin, E. D. & Torres Aleman, I., Nov 1 2016, In : Glia. 64, 11, p. 1962-1971 10 p.

Research output: Contribution to journalArticle

Open Access
19 Scopus citations
2015

Circuit-specific signaling in astrocyte-neuron networks in basal ganglia pathways

Martín, R., Bajo-Grañeras, R., Moratalla, R., Perea, G. & Araque, A., Aug 14 2015, In : Science. 349, 6249, p. 730-734 5 p.

Research output: Contribution to journalArticle

109 Scopus citations

Do stars govern our actions? Astrocyte involvement in rodent behavior

Oliveira, J. F., Sardinha, V. M., Guerra-Gomes, S., Araque, A. & Sousa, N., Sep 1 2015, In : Trends in Neurosciences. 38, 9, p. 535-549 15 p.

Research output: Contribution to journalReview article

65 Scopus citations

Endocannabinoids induce lateral long-term potentiation of transmitter release by stimulation of gliotransmission

Gómez-Gonzalo, M., Navarrete, M., Perea, G., Covelo, A., Martín-Fernández, M., Shigemoto, R., Luján, R. & Araque, A., Oct 2015, In : Cerebral Cortex. 25, 10, p. 3699-3712 14 p.

Research output: Contribution to journalArticle

46 Scopus citations
2014

Astrocytes in endocannabinoid signalling

Navarrete, M., Díez, A. & Araque, A., Oct 19 2014, In : Philosophical Transactions of the Royal Society B: Biological Sciences. 369, 1654

Research output: Contribution to journalReview article

44 Scopus citations

Functional MRI in mice lacking IP3-dependent calcium signaling in astrocytes

Jego, P., Pacheco-Torres, J., Araque, A. & Canals, S., Oct 1 2014, In : Journal of Cerebral Blood Flow and Metabolism. 34, 10, p. 1599-1603 5 p.

Research output: Contribution to journalArticle

27 Scopus citations

Glial biology in learning and cognition

Fields, R. D., Araque, A., Johansen-Berg, H., Lim, S. S., Lynch, G., Nave, K. A., Nedergaard, M., Perez, R., Sejnowski, T. & Wake, H., Oct 1 2014, In : Neuroscientist. 20, 5, p. 426-431 6 p.

Research output: Contribution to journalArticle

86 Scopus citations

Gliotransmitters travel in time and space

Araque, A., Carmignoto, G., Haydon, P. G., Oliet, S. H. R., Robitaille, R. & Volterra, A., Feb 19 2014, In : Neuron. 81, 4, p. 728-739 12 p.

Research output: Contribution to journalReview article

464 Scopus citations

Neuron-glia networks: Integral gear of brain function

Perea, G., Sur, M. & Araque, A., Nov 6 2014, In : Frontiers in Cellular Neuroscience. 8, November, p. 1-8 8 p., 378.

Research output: Contribution to journalReview article

114 Scopus citations

Structural and functional plasticity of astrocyte processes and dendritic spine interactions

Perez-Alvarez, A., Navarrete, M., Covelo, A., Martin, E. D. & Araque, A., Sep 17 2014, In : Journal of Neuroscience. 34, 38, p. 12738-12744 7 p.

Research output: Contribution to journalArticle

116 Scopus citations

The Cajal school and the physiological role of astrocytes: A way of thinking

Navarrete, M. & Araque, A., May 19 2014, In : Frontiers in Neuroanatomy. 8, MAY, 33.

Research output: Contribution to journalReview article

22 Scopus citations
2013

Astrocyte calcium signal and gliotransmission in human brain tissue

Navarrete, M., Perea, G., Maglio, L., Pastor, J., García De Sola, R. & Araque, A., May 1 2013, In : Cerebral Cortex. 23, 5, p. 1240-1246 7 p.

Research output: Contribution to journalArticle

70 Scopus citations

Astrocyte-neuron interaction at tripartite synapses

Pérez-Alvarez, A. & Araque, A., Nov 25 2013, In : Current Drug Targets. 14, 11, p. 1220-1224 5 p.

Research output: Contribution to journalArticle

59 Scopus citations

Confocal microscopy for astrocyte in vivo imaging: Recycle and reuse in microscopy

Perez-Alvarez, A., Araque, A. & Martin, E. D., Apr 7 2013, In : Frontiers in Cellular Neuroscience. APR

Research output: Contribution to journalArticle

14 Scopus citations
2012

Astrocytes mediate in vivo cholinergic-induced synaptic plasticity

Navarrete, M., Perea, G., de Sevilla, D. F., Gómez-Gonzalo, M., Núñez, A., Martín, E. D. & Araque, A., Feb 1 2012, In : PLoS biology. 10, 2, e1001259.

Research output: Contribution to journalArticle

220 Scopus citations

Astroglial excitability and gliotransmission: An appraisal of Ca 2+ as a signalling route

Zorec, R., Araque, A., Carmignoto, G., Haydon, P. G., Verkhratsky, A. & Parpura, V., 2012, In : ASN Neuro. 4, 2, p. 103-119 17 p.

Research output: Contribution to journalArticle

183 Scopus citations
2011

Artificial astrocytes improve neural network performance

Porto-Pazos, A. B., Veiguela, N., Mesejo, P., Navarrete, M., Alvarellos, A., Ibáñez, O., Pazos, A. & Araque, A., May 3 2011, In : PloS one. 6, 4, e19109.

Research output: Contribution to journalArticle

48 Scopus citations

Basal synaptic transmission: Astrocytes rule!

Navarrete, M. & Araque, A., Sep 2 2011, In : Cell. 146, 5, p. 675-677 3 p.

Research output: Contribution to journalShort survey

16 Scopus citations

Electrically driven insulation in the central nervous system

Araque, A. & Navarrete, M., Sep 16 2011, In : Science. 333, 6049, p. 1587-1588 2 p.

Research output: Contribution to journalShort survey

5 Scopus citations
2010

Endocannabinoids potentiate synaptic transmission through stimulation of astrocytes

Navarrete, M. & Araque, A., Oct 6 2010, In : Neuron. 68, 1, p. 113-126 14 p.

Research output: Contribution to journalArticle

254 Scopus citations

Glial cells in neuronal network function

Araque, A. & Navarrete, M., Aug 12 2010, In : Philosophical Transactions of the Royal Society B: Biological Sciences. 365, 1551, p. 2375-2381 7 p.

Research output: Contribution to journalReview article

141 Scopus citations

GLIA modulates synaptic transmission

Perea, G. & Araque, A., May 1 2010, In : Brain Research Reviews. 63, 1-2, p. 93-102 10 p.

Research output: Contribution to journalReview article

152 Scopus citations
2009

Astrocyte: Calcium signaling

Deitmer, J. W. & Araque, A., Jan 1 2009, Encyclopedia of Neuroscience. Elsevier Ltd, p. 565-572 8 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

4 Scopus citations

Synaptic information processing by astrocytes

Perea, G. & Araque, A., Jan 1 2009, Astrocytes in (Patho)Physiology of the Nervous System. Springer US, p. 287-300 14 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Scopus citations

Tripartite synapses: astrocytes process and control synaptic information

Perea, G., Navarrete, M. & Araque, A., Aug 1 2009, In : Trends in Neurosciences. 32, 8, p. 421-431 11 p.

Research output: Contribution to journalReview article

856 Scopus citations
2008

Astrocytes process synaptic information

Araque, A., Feb 1 2008, In : Neuron Glia Biology. 4, 1, p. 3-10 8 p.

Research output: Contribution to journalReview article

70 Scopus citations

DREAM mediates cAMP-dependent, Ca2+-induced stimulation of GFAP gene expression and regulates cortical astrogliogenesis

Cebolla, B., Fernández-Pérez, A., Perea, G., Araque, A. & Vallejo, M., Jun 25 2008, In : Journal of Neuroscience. 28, 26, p. 6703-6713 11 p.

Research output: Contribution to journalArticle

34 Scopus citations

Endocannabinoids Mediate Neuron-Astrocyte Communication

Navarrete, M. & Araque, A., Mar 27 2008, In : Neuron. 57, 6, p. 883-893 11 p.

Research output: Contribution to journalArticle

285 Scopus citations
2007

Adenosine released by astrocytes contributes to hypoxia-induced modulation of synaptic transmission

Martín, E. D., Fernández, M., Perea, G., Pascual, O., Haydon, P. G., Araque, A. & Ceña, V., Jan 1 2007, In : Glia. 55, 1, p. 36-45 10 p.

Research output: Contribution to journalArticle

148 Scopus citations

A new hybrid evolutionary mechanism based on unsupervised learning for Connectionist Systems

Porto, A., Araque, A., Rabuñal, J., Dorado, J. & Pazos, A., Oct 1 2007, In : Neurocomputing. 70, 16-18, p. 2799-2808 10 p.

Research output: Contribution to journalArticle

14 Scopus citations