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Research Output 1998 2019

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2019

The anti-parasitic agent suramin and several of its analogues are inhibitors of the DNA binding protein Mcm10

Paulson, C. N., John, K., Baxley, R. M., Kurniawan, F., Orellana, K., Francis, R., Sobeck, A., Eichman, B. F., Chazin, W. J., Aihara, H., Georg, G. I., Hawkinson, J. E. & Bielinsky, A. K., Aug 1 2019, In : Open biology. 9, 8, 190117.

Research output: Contribution to journalArticle

Open Access
Minichromosome Maintenance Proteins
Suramin
DNA-Binding Proteins
Fluorescence Polarization
Surface Plasmon Resonance
2017
7 Citations (Scopus)

FANCI and FANCD2 have common as well as independent functions during the cellular replication stress response

Thompson, E. L., Yeo, J. E., Lee, E. A., Kan, Y., Raghunandan, M., Wiek, C., Hanenberg, H., Schärer, O. D., Hendrickson, E. A. & Sobeck, A., Jan 1 2017, In : Nucleic acids research. 45, 20, p. 11837-11857 21 p.

Research output: Contribution to journalArticle

Open Access
Fanconi Anemia
Fanconi Anemia Complementation Group D2 Protein
Chromatin
Fanconi Anemia Complementation Group Proteins
Null Lymphocytes
2015
35 Citations (Scopus)

FANCD2, FANCJ and BRCA2 cooperate to promote replication fork recovery independently of the Fanconi Anemia core complex

Raghunandan, M., Chaudhury, I., Kelich, S. L., Hanenberg, H. & Sobeck, A., Feb 1 2015, In : Cell Cycle. 14, 3, p. 342-353 12 p.

Research output: Contribution to journalArticle

Fanconi Anemia
Chromatin
Aphidicolin
DNA Repair
Fanconi Anemia Complementation Group Proteins
35 Citations (Scopus)

FANCI Regulates Recruitment of the FA Core Complex at Sites of DNA Damage Independently of FANCD2

Castella, M., Jacquemont, C., Thompson, E. L., Yeo, J. E., Cheung, R. S., Huang, J. W., Sobeck, A., Hendrickson, E. A. & Taniguchi, T., Jan 1 2015, In : PLoS genetics. 11, 10, e1005563.

Research output: Contribution to journalArticle

Fanconi Anemia
anemia
DNA damage
DNA Damage
DNA
46 Citations (Scopus)

Regulation of the Rev1-pol ζ complex during bypass of a DNA interstrand cross-link

Budzowska, M., Graham, T. G. W., Sobeck, A., Waga, S. & Walter, J. C., Jan 1 2015, In : EMBO Journal. 34, 14, p. 1971-1985 15 p.

Research output: Contribution to journalArticle

DNA-Directed DNA Polymerase
Mutagenesis
DNA
Repair
DNA Replication
2014
46 Citations (Scopus)

CtIP mediates replication fork recovery in a FANCD2-regulated manner

Yeo, J. E., Lee, E. H., Hendrickson, E. A. & Sobeck, A., Jul 2014, In : Human molecular genetics. 23, 14, p. 3695-3705 11 p., ddu078.

Research output: Contribution to journalArticle

Fanconi Anemia
Proteins
Recombinational DNA Repair
Fanconi Anemia Complementation Group D2 Protein
DNA Repair-Deficiency Disorders
39 Citations (Scopus)
Aphidicolin
Fanconi Anemia
Chromatin
Fanconi Anemia Complementation Group D2 Protein
Exonucleases
2013
58 Citations (Scopus)

FANCD2 regulates BLM complex functions independently of FANCI to promote replication fork recovery

Chaudhury, I., Sareen, A., Raghunandan, M. & Sobeck, A., Jul 1 2013, In : Nucleic acids research. 41, 13, p. 6444-6459 16 p.

Research output: Contribution to journalArticle

Fanconi Anemia Complementation Group Proteins
Replication Protein A
Bloom Syndrome
Fanconi Syndrome
Fanconi Anemia
2012
37 Citations (Scopus)

Fanconi anemia proteins FANCD2 and FANCI exhibit different DNA damage responses during S-phase

Sareen, A., Chaudhury, I., Adams, N. & Sobeck, A., Sep 1 2012, In : Nucleic acids research. 40, 17, p. 8425-8439 15 p.

Research output: Contribution to journalArticle

Fanconi Anemia Complementation Group Proteins
Fanconi Anemia
S Phase
DNA Damage
Ataxia Telangiectasia
2009
28 Citations (Scopus)

A novel cell-free screen identifies a potent inhibitor of the fanconi anemia pathway

Lanclais, I., Sobeck, A., Stone, S., LaChapelle, A. & Hoatlin, M. E., Feb 15 2009, In : International Journal of Cancer. 124, 4, p. 783-792 10 p.

Research output: Contribution to journalArticle

Fanconi Anemia
Naphthoquinones
Cisplatin
Xenopus
DNA Damage
141 Citations (Scopus)

Human RAD50 Deficiency in a Nijmegen Breakage Syndrome-like Disorder

Waltes, R., Kalb, R., Gatei, M., Kijas, A. W., Stumm, M., Sobeck, A., Wieland, B., Varon, R., Lerenthal, Y., Lavin, M. F., Schindler, D. & Dörk, T., May 15 2009, In : American Journal of Human Genetics. 84, 5, p. 605-616 12 p.

Research output: Contribution to journalArticle

Nijmegen Breakage Syndrome
Ataxia Telangiectasia Mutated Proteins
G1 Phase Cell Cycle Checkpoints
Phenotype
Ataxia Telangiectasia
28 Citations (Scopus)

The Fanconi anemia protein FANCM is controlled by FANCD2 and the ATR/ATM pathways

Sobeck, A., Stone, S., Landais, I., de Graaf, B. & Hoatlin, M. E., Sep 18 2009, In : Journal of Biological Chemistry. 284, 38, p. 25560-25568 9 p.

Research output: Contribution to journalArticle

Fanconi Anemia Complementation Group Proteins
Automatic teller machines
DNA Damage
Fanconi Anemia
DNA
2008
128 Citations (Scopus)

RMI, a new OB-fold complex essential for Bloom syndrome protein to maintain genome stability

Xu, D., Guo, R., Sobeck, A., Bachrati, C. Z., Yang, J., Enomoto, T., Brown, G. W., Hoatlin, M. E., Hickson, I. D. & Wang, W., Oct 15 2008, In : Genes and Development. 22, 20, p. 2843-2855 13 p.

Research output: Contribution to journalArticle

Sister Chromatid Exchange
Genomic Instability
Bloom Syndrome
Oligonucleotides
Proteins
2007
30 Citations (Scopus)

DNA structure-induced recruitment and activation of the Fanconi anemia pathway protein FANCD2

Sobeck, A., Stone, S. & Hoatlin, M. E., Jun 1 2007, In : Molecular and cellular biology. 27, 12, p. 4283-4292 10 p.

Research output: Contribution to journalArticle

Fanconi Anemia Complementation Group Proteins
Fanconi Anemia
DNA
Xenopus laevis
DNA Replication
7 Citations (Scopus)

Identification, developmental expression and regulation of the Xenopus ortholog of human FANCG/XRCC9

Stone, S., Sobeck, A., van Kogelenberg, M., de Graaf, B., Joenje, H., Christian, J. & Hoatlin, M. E., Jul 1 2007, In : Genes to Cells. 12, 7, p. 841-851 11 p.

Research output: Contribution to journalArticle

Xenopus
Fanconi Anemia
Protein Isoforms
Leucine Zippers
Bone Neoplasms
2006
82 Citations (Scopus)

Fanconi anemia proteins are required to prevent accumulation of replication-associated DNA double-strand breaks

Sobeck, A., Stone, S., Costanzo, V., De Graaf, B., Reuter, T., De Winter, J., Wallisch, M., Akkari, Y., Olson, S., Wang, W., Joenje, H., Christian, J. L., Lupardus, P. J., Cimprich, K. A., Gautier, J. & Hoatlin, M. E., Jan 1 2006, In : Molecular and cellular biology. 26, 2, p. 425-437 13 p.

Research output: Contribution to journalArticle

Fanconi Anemia Complementation Group Proteins
Double-Stranded DNA Breaks
Mitomycin
Chromatin
DNA Breaks
2005
137 Citations (Scopus)

BLAP75, an essential component of Bloom's syndrome protein complexes that maintain genome integrity

Yin, J., Sobeck, A., Xu, C., Meetei, A. R., Hoatlin, M., Li, L. & Wang, W., Apr 6 2005, In : EMBO Journal. 24, 7, p. 1465-1476 12 p.

Research output: Contribution to journalArticle

Small Interfering RNA
Genes
Bloom Syndrome
Genome
Dwarfism
2004
53 Citations (Scopus)

The Fanconi anemia gene product FANCF is a flexible adaptor protein

Léveillé, F., Blom, E., Medhurst, A. L., Bier, P., Laghmani, E. H., Johnson, M., Rooimans, M. A., Sobeck, A., Waisfisz, Q., Arwert, F., Patel, K. J., Hoatlin, M. E., Joenje, H. & De Winter, J. P., Sep 17 2004, In : Journal of Biological Chemistry. 279, 38, p. 39421-39430 10 p.

Research output: Contribution to journalArticle

Fanconi Anemia Complementation Group Proteins
Fanconi Anemia
Fanconi Anemia Complementation Group F Protein
Genes
Amino Acids
1999
38 Citations (Scopus)

Sequence analysis of the ATM gene in 20 patients with RTOG grade 3 or 4 acute and/or late tissue radiation side effects

Oppitz, U., Bernthaler, U., Schindler, D., Sobeck, A., Hoehn, H., Platzer, M., Rosenthal, A. & Flentje, M., Jul 15 1999, In : International Journal of Radiation Oncology Biology Physics. 44, 5, p. 981-988 8 p.

Research output: Contribution to journalArticle

asynchronous transfer mode
Radiation Effects
genes
mutations
Sequence Analysis
1998

Infection of mice with mycobacterium bovis-bacillus calmette-guerin (BCG) suppresses allergen-induced airway eosinophilia

Erb, K. J., Holloway, J. W., Sobeck, A., Moll, H. & Le-Gros, G., Dec 1 1998, In : Pneumologie. 52, 7, p. 420-421 2 p.

Research output: Contribution to journalArticle

Eosinophilia
Mycobacterium bovis
Allergens
Infection
351 Citations (Scopus)

Infection of mice with Mycobacterium bovis-Bacillus Calmette-Guerin (BCG) suppresses allergen-induced airway eosinophilia

Erb, K. J., Holloway, J. W., Sobeck, A., Moll, H. & Le Gros, G., Feb 16 1998, In : Journal of Experimental Medicine. 187, 4, p. 561-569 9 p.

Research output: Contribution to journalArticle

Eosinophilia
Mycobacterium bovis
Allergens
Ovalbumin
Infection